Development Level

Tbio 118 | 11,445
Tchem 32 | 1,598
Tclin 25 | 613
Tdark 13 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

abnormal behavior 10 | 298
preweaning lethality, complete... 10 | 979
abnormal locomotor behavior 6 | 24
hyperactivity 6 | 148
impaired glucose tolerance 6 | 75
increased total body fat amoun... 6 | 134
decreased grip strength 5 | 116
decreased lean body mass 5 | 135
preweaning lethality, incomple... 5 | 499
edema 4 | 59
increased circulating alkaline... 4 | 122
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
decreased circulating alkaline... 3 | 46
decreased circulating glucose ... 3 | 126
decreased fasted circulating g... 3 | 65
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 76
short tibia 3 | 97
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased basophil cell number 2 | 16
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
decreased vertical activity 2 | 208
enlarged stomach 2 | 2
hemorrhage 2 | 23
hypoactivity 2 | 132
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased spleen weight 2 | 10
small thymus 2 | 16
thrombocytosis 2 | 27
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased hemoglobin content 1 | 68
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

Carcinoma 130 | 11,493
atypical teratoid / rhabdoid tumor 103 | 5,112
medulloblastoma, large-cell 103 | 6,241
glioblastoma 102 | 5,792
ependymoma 91 | 4,679
adult high grade glioma 84 | 3,801
Astrocytoma, Pilocytic 79 | 3,081
osteosarcoma 76 | 7,950
ovarian cancer 76 | 8,520
psoriasis 76 | 6,694
oligodendroglioma 73 | 2,850
group 3 medulloblastoma 65 | 4,104
primitive neuroectodermal tumor 65 | 3,035
lung cancer 59 | 4,740
Schizophrenia 56 | 1,160
astrocytic glioma 56 | 2,597
Kidney cancer 52 | 2,613
Cancer 46 | 2,499
Breast cancer 44 | 3,578
pituitary cancer 43 | 1,972
subependymal giant cell astrocytoma 43 | 2,287
Pick disease 42 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
malignant mesothelioma 40 | 3,232
Bipolar Disorder 39 | 666
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
Alzheimer's disease 37 | 658
lung carcinoma 37 | 2,843
Epilepsy 36 | 792
invasive ductal carcinoma 36 | 2,951
Depressive disorder 33 | 409
Neurodegenerative disease 32 | 414
group 4 medulloblastoma 31 | 1,855
Parkinson's disease 30 | 392
diabetes mellitus 28 | 1,728
Mental Depression 27 | 333
Seizures 27 | 596
colon cancer 26 | 1,478
cystic fibrosis 26 | 1,696
non-small cell lung cancer 26 | 2,890
Alcoholic Intoxication, Chronic 25 | 289
astrocytoma 25 | 1,146
interstitial cystitis 25 | 2,312
pancreatic cancer 25 | 2,398
lung adenocarcinoma 24 | 2,716
Down syndrome 23 | 499
Intellectual disability 23 | 1,016
Melanoma 22 | 711
Obesity 22 | 678
Dementia 21 | 175
adrenocortical carcinoma 21 | 1,428
Multiple Sclerosis 20 | 540
Autosomal recessive predisposition 19 | 1,442
Toxic encephalopathy 19 | 141
ulcerative colitis 19 | 1,819
Autistic Disorder 18 | 364
Liver cancer 18 | 604
Major Depressive Disorder 18 | 301
Skin cancer 18 | 469
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
tuberculosis 18 | 2,010
Mood Disorders 17 | 184
pediatric high grade glioma 17 | 1,064
Amyotrophic lateral sclerosis 15 | 451
cutaneous lupus erythematosus 15 | 1,057
progressive supranuclear palsy 15 | 676
Cerebrovascular disease 14 | 238
Hypertension 14 | 396
Neuropathy 14 | 261
Pain agnosia 14 | 104
breast carcinoma 14 | 1,638
Huntington's disease 13 | 76
Multiple myeloma 13 | 1,332
Unipolar Depression 13 | 250
acute quadriplegic myopathy 13 | 1,158
ductal carcinoma in situ 13 | 1,745
spina bifida 13 | 1,074
Alcohol dependence 12 | 107
Asthma 12 | 385
Heart disease 12 | 306
Nerve Degeneration 12 | 121
Parkinsonian Disorders 12 | 56
Vascular disease 12 | 319
juvenile dermatomyositis 12 | 1,187
Cocaine-Related Disorders 11 | 92
Duchenne muscular dystrophy 11 | 601
Dysarthria 11 | 192
Osteoporosis 11 | 363
Pain 11 | 103
non primary Sjogren syndrome sicca 11 | 891
Atopic dermatitis 10 | 952
Brain disease 10 | 96
Constipation 10 | 181
Hyperactive behavior 10 | 91
Hyperalgesia 10 | 83
aldosterone-producing adenoma 10 | 665
gastric carcinoma 10 | 807
Mental and motor retardation 9 | 608
Migraine 9 | 83

Tissue

Endocrine System 186 | 18,159
Female tissues 181 | 17,400
Male tissues 179 | 17,142
Nervous System 178 | 16,725
Digestive Tract 177 | 17,369
Skin and soft tissues 177 | 17,230
Liver and Pancreas 175 | 16,750
Blood and immune system 170 | 16,909
Urinary Tract 170 | 16,678
Respiratory system 159 | 16,393
Cardiovascular System 148 | 15,192

Target Family

Non-IDG 111 | 12,091
Ion Channel 28 | 344
Enzyme 23 | 4,145
Kinase 8 | 634
Transporter 7 | 473
GPCR 5 | 408
Epigenetic 4 | 242
Transcription Factor 2 | 1,400

Compartment GO Term

Neuronal cell body 188 | 188
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Zinc finger protein 677 ZNF677 Tdark Transcription Factor -0.05115 1.13 52
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Zinc finger protein 385A ZNF385A Tbio Non-IDG -0.03141 1.24 99
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100