Development Level

Tbio 68 | 10,625
Tchem 35 | 1,890
Tclin 33 | 602
Tdark 2 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

abnormal behavior 8 | 226
preweaning lethality, incomple... 6 | 260
increased circulating sodium l... 5 | 71
increased lean body mass 5 | 107
decreased grip strength 4 | 123
decreased lean body mass 4 | 195
preweaning lethality, complete... 4 | 633
decreased body weight 3 | 174
decreased fasted circulating g... 3 | 49
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased circulating chloride... 3 | 43
abnormal behavioral response t... 2 | 52
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal testis morphology 2 | 30
decreased bone mineral content 2 | 157
decreased circulating LDL chol... 2 | 37
decreased prepulse inhibition 2 | 52
enlarged epididymis 2 | 27
enlarged heart 2 | 111
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased erythrocyte cell num... 2 | 26
increased or absent threshold ... 2 | 128
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal kidney morphology 1 | 30
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spine curvature 1 | 7
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
absent testes 1 | 2
corneal opacity 1 | 25
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
increased prepulse inhibition 1 | 21
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
limb grasping 1 | 35
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
shortened RR interval 1 | 19
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 71 | 6,234
glioblastoma 69 | 5,572
psoriasis 60 | 6,685
oligodendroglioma 56 | 2,849
pilocytic astrocytoma 56 | 3,086
osteosarcoma 54 | 7,933
atypical teratoid / rhabdoid tumor 52 | 4,369
Schizophrenia 49 | 503
pediatric high grade glioma 46 | 2,712
primitive neuroectodermal tumor 46 | 3,031
ovarian cancer 44 | 8,492
Cancer 43 | 2,346
lung carcinoma 42 | 2,844
Alzheimer's disease 40 | 644
Parkinson's disease 40 | 364
Epilepsy 39 | 346
lung cancer 36 | 4,473
Pain agnosia 33 | 99
Pick disease 33 | 1,893
astrocytoma 32 | 1,493
Toxic encephalopathy 30 | 131
astrocytic glioma 30 | 2,241
ependymoma 30 | 2,514
diabetes mellitus 29 | 1,663
Migraine 28 | 79
Obesity 28 | 616
subependymal giant cell astrocytoma 28 | 2,287
malignant mesothelioma 27 | 3,163
Seizures 25 | 95
posterior fossa group A ependymoma 25 | 1,511
Bipolar Disorder 24 | 266
Cocaine-Related Disorders 24 | 88
Carcinoma 23 | 2,147
adult high grade glioma 23 | 2,148
Autistic Disorder 22 | 320
Hypertension 22 | 293
Pain 22 | 70
group 3 medulloblastoma 22 | 2,254
medulloblastoma 22 | 1,524
pituitary cancer 22 | 1,972
Alcohol dependence 21 | 107
Neurodegenerative disease 20 | 383
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
sonic hedgehog group medulloblastoma 20 | 1,482
Cerebrovascular disease 19 | 231
Hyperalgesia 19 | 71
invasive ductal carcinoma 19 | 2,950
lung adenocarcinoma 19 | 2,714
posterior fossa group B ependymoma 19 | 1,530
Intellectual disability 18 | 573
Neuropathy 18 | 210
atypical teratoid/rhabdoid tumor 18 | 1,095
non-small cell lung cancer 18 | 2,798
Attention deficit hyperactivity disorder 17 | 156
Breast cancer 17 | 3,099
Huntington's disease 17 | 72
Major Depressive Disorder 17 | 106
Dementia 16 | 129
Diarrhea 16 | 155
Down syndrome 16 | 548
Irritable bowel syndrome 16 | 59
colon cancer 16 | 1,475
Asthma 15 | 349
Substance abuse 15 | 55
cystic fibrosis 15 | 1,670
group 4 medulloblastoma 15 | 1,875
interstitial cystitis 15 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
Hypotension 14 | 53
Kidney disease 14 | 397
Substance Withdrawal Syndrome 14 | 55
Amyotrophic Lateral Sclerosis 13 | 432
Brain disease 13 | 84
Hypertensive disease 13 | 193
Hypoglycemia 13 | 81
Withdrawal disorder 13 | 19
adrenocortical carcinoma 13 | 1,427
Adenoma 12 | 165
Amnestic disorder 12 | 37
Amphetamine-Related Disorders 12 | 74
Endometriosis 12 | 535
Memory Disorders 12 | 36
Nerve Degeneration 12 | 73
aldosterone-producing adenoma 12 | 664
ulcerative colitis 12 | 2,087
Bradycardia 11 | 24
Constipation 11 | 43
Cushing's syndrome 11 | 47
Hyperactive behavior 11 | 31
Hypothyroidism 11 | 89
Pancreatitis 11 | 97
Status Epilepticus 11 | 85
breast carcinoma 11 | 1,614
ductal carcinoma in situ 11 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
tuberculosis 11 | 1,563
Depressive disorder 10 | 48
Narcolepsy 10 | 69
Parkinson Disease 10 | 105

Tissue

Endocrine System 137 | 18,512
Female tissues 137 | 18,647
Nervous System 136 | 18,561
Digestive Tract 135 | 18,473
Skin and soft tissues 135 | 18,115
Liver and Pancreas 134 | 18,136
Cardiovascular System 133 | 17,958
Urinary Tract 133 | 18,444
Blood and immune system 130 | 17,995
Male tissues 128 | 17,969
Respiratory system 125 | 17,484

Target Family

Non-IDG 64 | 11,969
Enzyme 25 | 4,146
Ion Channel 16 | 341
Transporter 13 | 473
GPCR 12 | 408
Kinase 5 | 634
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Neuron projection terminus 138 | 138
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synapsin-1 SYN1 Tbio Non-IDG -2.85684 687.9 716
Metabotropic glutamate receptor 7 GRM7 Tbio GPCR -2.23649 186.6 266
Short transient receptor potential channel 7 TRPC7 Tbio Ion Channel -2.43795 198.9 193
Tryptophan 5-hydroxylase 1 TPH1 Tclin Enzyme -2.90440 740.7 364
Tachykinin-3 TAC3 Tchem Non-IDG -2.66846 402.5 172
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Sodium- and chloride-dependent glycine transporter 2 SLC6A5 Tchem Transporter -2.28704 183.7 39
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tchem Ion Channel -1.73535 52.7 80
Synaptotagmin-2 SYT2 Tbio Non-IDG -1.91450 69.3 204
Beta-nerve growth factor NGF Tchem Non-IDG -4.00388 10626.8 510