Development Level

Tbio 75 | 11,445
Tclin 37 | 613
Tchem 33 | 1,598
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 9 | 499
abnormal behavior 8 | 298
increased circulating sodium l... 7 | 71
decreased bone mineral content 4 | 151
decreased fasted circulating g... 4 | 65
hyperactivity 4 | 148
hypoactivity 4 | 132
increased circulating chloride... 4 | 41
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal testis morphology 3 | 43
decreased circulating serum al... 3 | 82
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased neutrophil cell numb... 3 | 42
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased mean corpuscular vol... 3 | 92
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal behavioral response t... 2 | 66
abnormal heart morphology 2 | 162
abnormal sensory capabilities-... 2 | 8
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating total pr... 2 | 49
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased erythrocyte cell num... 2 | 39
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
small testis 2 | 58
tremors 2 | 39
abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
prolonged RR interval 1 | 8
short tibia 1 | 97
small heart 1 | 10
thin ventricular wall 1 | 24

Disease

Carcinoma 97 | 11,493
glioblastoma 81 | 5,792
medulloblastoma, large-cell 79 | 6,241
Schizophrenia 77 | 1,160
ependymoma 74 | 4,679
atypical teratoid / rhabdoid tumor 71 | 5,112
adult high grade glioma 64 | 3,801
psoriasis 64 | 6,694
Astrocytoma, Pilocytic 61 | 3,081
oligodendroglioma 61 | 2,850
Bipolar Disorder 60 | 666
group 3 medulloblastoma 59 | 4,104
Depressive disorder 56 | 409
osteosarcoma 56 | 7,950
Epilepsy 51 | 792
Mental Depression 50 | 333
astrocytic glioma 50 | 2,597
primitive neuroectodermal tumor 50 | 3,035
Alcoholic Intoxication, Chronic 48 | 289
ovarian cancer 48 | 8,520
Alzheimer's disease 47 | 658
Parkinson's disease 47 | 392
Cancer 44 | 2,499
lung carcinoma 44 | 2,843
lung cancer 41 | 4,740
Major Depressive Disorder 39 | 301
Pick disease 38 | 1,894
Toxic encephalopathy 37 | 141
Seizures 35 | 596
Unipolar Depression 35 | 250
Pain agnosia 34 | 104
Hypertension 32 | 396
Mood Disorders 32 | 184
Kidney cancer 30 | 2,613
diabetes mellitus 30 | 1,728
subependymal giant cell astrocytoma 30 | 2,287
Migraine 29 | 83
malignant mesothelioma 29 | 3,232
Obesity 28 | 678
Cocaine-Related Disorders 27 | 92
Intellectual disability 27 | 1,016
Autistic Disorder 25 | 364
pituitary cancer 25 | 1,972
Alcohol dependence 24 | 107
Attention deficit hyperactivity disorder 24 | 278
Breast cancer 24 | 3,578
Autosomal recessive predisposition 23 | 1,442
Pain 23 | 103
Cerebrovascular disease 22 | 238
Hyperalgesia 22 | 83
Neuropathy 22 | 261
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
non-small cell lung cancer 22 | 2,890
Neurodegenerative disease 21 | 414
invasive ductal carcinoma 21 | 2,951
lung adenocarcinoma 21 | 2,716
Dementia 20 | 175
Huntington's disease 19 | 76
Constipation 18 | 181
Brain disease 17 | 96
Diarrhea 17 | 253
astrocytoma 17 | 1,146
colon cancer 17 | 1,478
interstitial cystitis 17 | 2,312
Amyotrophic lateral sclerosis 16 | 451
Asthma 16 | 385
Down syndrome 16 | 499
Irritable bowel syndrome 16 | 60
Substance abuse 16 | 59
cystic fibrosis 16 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
Hyperactive behavior 15 | 91
Hypotension 15 | 82
Infantile onset 15 | 238
Kidney disease 15 | 430
Nerve Degeneration 15 | 121
Hypertensive disease 14 | 292
Status Epilepticus 14 | 98
Substance Withdrawal Syndrome 14 | 55
adrenocortical carcinoma 14 | 1,428
Amnestic disorder 13 | 35
Hypoglycemia 13 | 152
Psychotic Disorders 13 | 151
Withdrawal disorder 13 | 19
group 4 medulloblastoma 13 | 1,855
Adenoma 12 | 167
Amphetamine-Related Disorders 12 | 74
Cocaine Dependence 12 | 51
Dystonia 12 | 164
Hyperkinesis 12 | 32
Memory Disorders 12 | 40
Parkinsonian Disorders 12 | 56
aldosterone-producing adenoma 12 | 665
breast carcinoma 12 | 1,638
tuberculosis 12 | 2,010
ulcerative colitis 12 | 1,819
Endometriosis 11 | 540
ductal carcinoma in situ 11 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962

Tissue

Endocrine System 144 | 18,159
Nervous System 137 | 16,725
Female tissues 136 | 17,400
Skin and soft tissues 135 | 17,230
Digestive Tract 134 | 17,369
Liver and Pancreas 130 | 16,750
Male tissues 128 | 17,142
Urinary Tract 125 | 16,678
Blood and immune system 124 | 16,909
Respiratory system 119 | 16,393
Cardiovascular System 100 | 15,192

Target Family

Non-IDG 67 | 12,091
Enzyme 28 | 4,145
Ion Channel 17 | 344
GPCR 14 | 408
Transporter 13 | 473
Kinase 6 | 634
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Neuron projection terminus 148 | 148
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Histamine H3 receptor HRH3 Tclin GPCR -2.76107 570.2 318
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Neurotensin/neuromedin N NTS Tbio Non-IDG -3.56154 3627.6 183