Development Level

Tbio 68 | 10,625
Tchem 35 | 1,890
Tclin 33 | 602
Tdark 2 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 2 | 102

IMPC Phenotype

abnormal behavior 8 | 226
preweaning lethality, incomple... 6 | 260
increased circulating sodium l... 5 | 71
increased lean body mass 5 | 107
decreased grip strength 4 | 123
decreased lean body mass 4 | 195
preweaning lethality, complete... 4 | 633
decreased body weight 3 | 174
decreased fasted circulating g... 3 | 49
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased circulating chloride... 3 | 43
abnormal behavioral response t... 2 | 52
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal testis morphology 2 | 30
decreased bone mineral content 2 | 157
decreased circulating LDL chol... 2 | 37
decreased prepulse inhibition 2 | 52
enlarged epididymis 2 | 27
enlarged heart 2 | 111
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased erythrocyte cell num... 2 | 26
increased or absent threshold ... 2 | 128
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal kidney morphology 1 | 30
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spine curvature 1 | 7
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
absent testes 1 | 2
corneal opacity 1 | 25
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
increased prepulse inhibition 1 | 21
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
limb grasping 1 | 35
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
shortened RR interval 1 | 19
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 71 | 6,234
glioblastoma 69 | 5,572
psoriasis 60 | 6,685
oligodendroglioma 56 | 2,849
pilocytic astrocytoma 56 | 3,086
osteosarcoma 54 | 7,933
atypical teratoid / rhabdoid tumor 52 | 4,369
Schizophrenia 49 | 503
pediatric high grade glioma 46 | 2,712
primitive neuroectodermal tumor 46 | 3,031
ovarian cancer 44 | 8,491
Cancer 43 | 2,346
lung carcinoma 42 | 2,844
Alzheimer's disease 40 | 644
Parkinson's disease 40 | 364
Epilepsy 39 | 346
lung cancer 36 | 4,473
Pain agnosia 33 | 99
Pick disease 33 | 1,893
astrocytoma 32 | 1,493
Toxic encephalopathy 30 | 131
astrocytic glioma 30 | 2,241
ependymoma 30 | 2,514
diabetes mellitus 29 | 1,663
Migraine 28 | 79
Obesity 28 | 616
subependymal giant cell astrocytoma 28 | 2,287
malignant mesothelioma 27 | 3,163
Seizures 25 | 95
posterior fossa group A ependymoma 25 | 1,511
Bipolar Disorder 24 | 266
Cocaine-Related Disorders 24 | 88
Carcinoma 23 | 2,147
adult high grade glioma 23 | 2,148
Autistic Disorder 22 | 320
Hypertension 22 | 293
Pain 22 | 70
group 3 medulloblastoma 22 | 2,254
medulloblastoma 22 | 1,524
pituitary cancer 22 | 1,972
Alcohol dependence 21 | 107
Neurodegenerative disease 20 | 383
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
sonic hedgehog group medulloblastoma 20 | 1,482
Cerebrovascular disease 19 | 231
Hyperalgesia 19 | 71
invasive ductal carcinoma 19 | 2,950
lung adenocarcinoma 19 | 2,714
posterior fossa group B ependymoma 19 | 1,530
Intellectual disability 18 | 573
Neuropathy 18 | 210
atypical teratoid/rhabdoid tumor 18 | 1,095
non-small cell lung cancer 18 | 2,798
Attention deficit hyperactivity disorder 17 | 156
Breast cancer 17 | 3,098
Huntington's disease 17 | 72
Major Depressive Disorder 17 | 106
Dementia 16 | 129
Diarrhea 16 | 155
Down syndrome 16 | 548
Irritable bowel syndrome 16 | 59
colon cancer 16 | 1,475
Asthma 15 | 349
Substance abuse 15 | 55
cystic fibrosis 15 | 1,670
group 4 medulloblastoma 15 | 1,875
interstitial cystitis 15 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
Hypotension 14 | 53
Kidney disease 14 | 397
Substance Withdrawal Syndrome 14 | 55
Amyotrophic Lateral Sclerosis 13 | 432
Brain disease 13 | 84
Hypertensive disease 13 | 193
Hypoglycemia 13 | 81
Withdrawal disorder 13 | 19
adrenocortical carcinoma 13 | 1,427
Adenoma 12 | 165
Amnestic disorder 12 | 37
Amphetamine-Related Disorders 12 | 74
Endometriosis 12 | 535
Memory Disorders 12 | 36
Nerve Degeneration 12 | 73
aldosterone-producing adenoma 12 | 664
ulcerative colitis 12 | 2,087
Bradycardia 11 | 24
Constipation 11 | 43
Cushing's syndrome 11 | 47
Hyperactive behavior 11 | 31
Hypothyroidism 11 | 89
Pancreatitis 11 | 97
Status Epilepticus 11 | 85
breast carcinoma 11 | 1,614
ductal carcinoma in situ 11 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
tuberculosis 11 | 1,563
Depressive disorder 10 | 48
Narcolepsy 10 | 69
Parkinson Disease 10 | 105

Tissue

Endocrine System 137 | 18,511
Female tissues 137 | 18,646
Nervous System 136 | 18,560
Digestive Tract 135 | 18,472
Skin and soft tissues 135 | 18,114
Liver and Pancreas 134 | 18,135
Cardiovascular System 133 | 17,957
Urinary Tract 133 | 18,443
Blood and immune system 130 | 17,994
Male tissues 128 | 17,968
Respiratory system 125 | 17,483

Target Family

Non-IDG 64 | 11,969
Enzyme 25 | 4,146
Ion Channel 16 | 341
Transporter 13 | 473
GPCR 12 | 408
Kinase 5 | 634
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Neuron projection terminus 138 | 138
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.53667 324.2 196
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
TBC1 domain family member 24 TBC1D24 Tbio Non-IDG -2.22045 137.3 20
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.57398 3724.8 253
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.91847 8071.2 168
Substance-P receptor TACR1 Tclin GPCR -3.09243 1193.3 417
Oxytocin-neurophysin 1 OXT Tbio Non-IDG -4.17412 14677.4 133