Development Level

Tbio 476 | 11,445
Tchem 111 | 1,598
Tclin 91 | 613
Tdark 33 | 6,588

Collection

Ion Channel: IDG Consortium (T... 8 | 99
Kinase: IDG Consortium (Comple... 4 | 37
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 39 | 979
preweaning lethality, incomple... 30 | 499
abnormal behavior 29 | 298
decreased total body fat amoun... 16 | 207
hyperactivity 16 | 148
decreased vertical activity 15 | 208
embryonic lethality prior to t... 15 | 278
abnormal bone structure 13 | 187
embryonic lethality prior to o... 13 | 239
increased total body fat amoun... 12 | 134
abnormal embryo size 11 | 220
decreased body weight 10 | 161
decreased lean body mass 10 | 135
decreased bone mineral content 9 | 151
decreased grip strength 9 | 116
increased circulating chloride... 9 | 41
increased circulating sodium l... 9 | 71
increased lean body mass 9 | 172
decreased circulating choleste... 8 | 93
decreased circulating serum al... 8 | 82
decreased fasted circulating g... 8 | 65
enlarged heart 8 | 210
hypoactivity 8 | 132
increased bone mineral content 8 | 108
abnormal behavioral response t... 7 | 66
abnormal gait 7 | 69
abnormal retina morphology 7 | 71
decreased circulating HDL chol... 7 | 68
impaired glucose tolerance 7 | 75
increased circulating alkaline... 7 | 122
decreased circulating alkaline... 6 | 46
decreased circulating total pr... 6 | 49
decreased startle reflex 6 | 75
increased circulating triglyce... 6 | 42
increased fasted circulating g... 6 | 76
limb grasping 6 | 41
short tibia 6 | 97
tremors 6 | 39
abnormal eye morphology 5 | 68
abnormal heart morphology 5 | 162
abnormal locomotor behavior 5 | 24
cataract 5 | 92
decreased circulating alanine ... 5 | 47
decreased circulating glucose ... 5 | 126
decreased neutrophil cell numb... 5 | 42
edema 5 | 59
increased heart weight 5 | 62
increased mean corpuscular vol... 5 | 92
increased or absent threshold ... 5 | 101
increased startle reflex 5 | 112
prolonged QT interval 5 | 38
prolonged ST segment 5 | 36
small testis 5 | 58
abnormal sleep behavior 4 | 70
abnormal testis morphology 4 | 43
decreased bone mineral density 4 | 126
decreased circulating LDL chol... 4 | 38
decreased circulating aspartat... 4 | 34
decreased circulating insulin ... 4 | 76
decreased mean corpuscular vol... 4 | 79
embryonic growth retardation 4 | 106
improved glucose tolerance 4 | 79
increased lymphocyte cell numb... 4 | 32
increased red blood cell distr... 4 | 34
increased vertical activity 4 | 24
prenatal lethality prior to he... 4 | 87
abnormal coat-hair pigmentatio... 3 | 64
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
abnormal skin morphology 3 | 50
decreased basophil cell number 3 | 16
decreased caudal vertebrae num... 3 | 53
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased mean platelet volume 3 | 25
hemorrhage 3 | 23
hydrometra 3 | 53
increased blood urea nitrogen ... 3 | 48
increased circulating iron lev... 3 | 30
increased erythrocyte cell num... 3 | 39
increased mean platelet volume 3 | 45
increased neutrophil cell numb... 3 | 46
increased prepulse inhibition 3 | 32
male infertility 3 | 123
small superior vagus ganglion 3 | 74
thin ventricular wall 3 | 24
thrombocytosis 3 | 27
abnormal epididymis morphology 2 | 42
abnormal retinal vasculature m... 2 | 27
abnormal vertebrae morphology 2 | 18
decreased hemoglobin content 2 | 68
increased circulating amylase ... 2 | 25
increased circulating bilirubi... 2 | 16
increased circulating free fat... 2 | 20
increased circulating phosphat... 2 | 26
increased circulating potassiu... 2 | 29
increased mean corpuscular hem... 2 | 96
pallor 2 | 34

Disease

Carcinoma 523 | 11,493
medulloblastoma, large-cell 395 | 6,241
glioblastoma 383 | 5,792
atypical teratoid / rhabdoid tumor 360 | 5,112
ependymoma 330 | 4,679
ovarian cancer 323 | 8,520
adult high grade glioma 308 | 3,801
osteosarcoma 306 | 7,950
psoriasis 289 | 6,694
Astrocytoma, Pilocytic 266 | 3,081
group 3 medulloblastoma 265 | 4,104
oligodendroglioma 260 | 2,850
lung cancer 222 | 4,740
astrocytic glioma 221 | 2,597
primitive neuroectodermal tumor 218 | 3,035
Schizophrenia 206 | 1,160
Kidney cancer 203 | 2,613
lung carcinoma 177 | 2,843
Breast cancer 176 | 3,578
Cancer 171 | 2,499
malignant mesothelioma 167 | 3,232
subependymal giant cell astrocytoma 162 | 2,287
Pick disease 155 | 1,894
Bipolar Disorder 149 | 666
intraductal papillary-mucinous adenoma (IPMA) 141 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 137 | 3,291
Alzheimer's disease 136 | 658
invasive ductal carcinoma 134 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 133 | 2,989
pituitary cancer 131 | 1,972
Epilepsy 124 | 792
non-small cell lung cancer 121 | 2,890
lung adenocarcinoma 115 | 2,716
Depressive disorder 113 | 409
Intellectual disability 106 | 1,016
Parkinson's disease 101 | 392
interstitial cystitis 101 | 2,312
group 4 medulloblastoma 100 | 1,855
pancreatic cancer 100 | 2,398
Mental Depression 94 | 333
Seizures 93 | 596
diabetes mellitus 93 | 1,728
colon cancer 91 | 1,478
cystic fibrosis 90 | 1,696
Alcoholic Intoxication, Chronic 87 | 289
Neurodegenerative disease 86 | 414
tuberculosis 85 | 2,010
breast carcinoma 82 | 1,638
Autosomal recessive predisposition 81 | 1,442
ulcerative colitis 77 | 1,819
Autistic Disorder 76 | 364
Toxic encephalopathy 76 | 141
ductal carcinoma in situ 76 | 1,745
Liver cancer 73 | 604
Major Depressive Disorder 70 | 301
Obesity 70 | 678
astrocytoma 70 | 1,146
adrenocortical carcinoma 65 | 1,428
Neuropathy 63 | 261
Amyotrophic lateral sclerosis 60 | 451
Unipolar Depression 60 | 250
Melanoma 59 | 711
Mood Disorders 58 | 184
Down syndrome 57 | 499
Dementia 55 | 175
Dull intelligence 54 | 645
Low intelligence 54 | 645
Mental Retardation 54 | 645
Mental deficiency 54 | 645
Poor school performance 54 | 645
Hypertension 53 | 396
pediatric high grade glioma 53 | 1,064
Skin cancer 51 | 469
Cerebrovascular disease 50 | 238
cutaneous lupus erythematosus 50 | 1,057
juvenile dermatomyositis 50 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 50 | 1,962
Multiple myeloma 49 | 1,332
Rheumatoid arthritis 48 | 1,191
acute quadriplegic myopathy 48 | 1,158
primary pancreatic ductal adenocarcinoma 48 | 1,109
Atopic dermatitis 47 | 952
Multiple Sclerosis 47 | 540
Cognitive delay 46 | 608
Global developmental delay 46 | 608
Mental and motor retardation 46 | 608
Cocaine-Related Disorders 45 | 92
Attention deficit hyperactivity disorder 44 | 278
Muscle hypotonia 44 | 571
Pain agnosia 44 | 104
aldosterone-producing adenoma 44 | 665
spina bifida 44 | 1,074
progressive supranuclear palsy 43 | 676
Brain disease 42 | 96
dermatomyositis 42 | 966
Alcohol dependence 40 | 107
Heart disease 40 | 306
Kidney disease 40 | 430
nasopharyngeal carcinoma 40 | 1,058
Asthma 39 | 385

Tissue

Endocrine System 696 | 18,159
Nervous System 681 | 16,725
Female tissues 675 | 17,400
Digestive Tract 670 | 17,369
Skin and soft tissues 666 | 17,230
Male tissues 660 | 17,142
Liver and Pancreas 648 | 16,750
Blood and immune system 643 | 16,909
Urinary Tract 637 | 16,678
Respiratory system 627 | 16,393
Cardiovascular System 575 | 15,192

Target Family

Non-IDG 425 | 12,091
Enzyme 98 | 4,145
Ion Channel 57 | 344
Kinase 46 | 634
GPCR 43 | 408
Transporter 23 | 473
Transcription Factor 12 | 1,400
Epigenetic 6 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Neuron projection 711 | 711
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182