Development Level

Tbio 455 | 11,178
Tchem 124 | 1,885
Tclin 90 | 612
Tdark 32 | 6,569

Collection

Ion Channel: IDG Consortium (T... 8 | 99
Kinase: IDG Consortium (Comple... 4 | 37
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 39 | 979
abnormal behavior 29 | 298
preweaning lethality, incomple... 29 | 499
decreased total body fat amoun... 16 | 207
hyperactivity 16 | 148
decreased vertical activity 15 | 208
embryonic lethality prior to t... 15 | 278
abnormal bone structure 13 | 187
embryonic lethality prior to o... 13 | 239
increased total body fat amoun... 12 | 134
abnormal embryo size 11 | 220
decreased body weight 10 | 161
decreased lean body mass 10 | 135
decreased bone mineral content 9 | 151
decreased grip strength 9 | 116
increased circulating chloride... 9 | 41
increased circulating sodium l... 9 | 71
increased lean body mass 9 | 172
decreased circulating choleste... 8 | 93
decreased circulating serum al... 8 | 82
decreased fasted circulating g... 8 | 65
enlarged heart 8 | 210
hypoactivity 8 | 132
increased bone mineral content 8 | 108
abnormal behavioral response t... 7 | 66
abnormal gait 7 | 69
abnormal retina morphology 7 | 71
decreased circulating HDL chol... 7 | 68
impaired glucose tolerance 7 | 75
increased circulating alkaline... 7 | 122
decreased circulating alkaline... 6 | 46
decreased circulating total pr... 6 | 49
decreased startle reflex 6 | 75
increased circulating triglyce... 6 | 42
increased fasted circulating g... 6 | 76
limb grasping 6 | 41
short tibia 6 | 97
tremors 6 | 39
abnormal eye morphology 5 | 68
abnormal heart morphology 5 | 162
abnormal locomotor behavior 5 | 24
cataract 5 | 92
decreased circulating alanine ... 5 | 47
decreased circulating glucose ... 5 | 126
decreased neutrophil cell numb... 5 | 42
edema 5 | 59
increased heart weight 5 | 62
increased mean corpuscular vol... 5 | 92
increased or absent threshold ... 5 | 101
increased startle reflex 5 | 112
prolonged QT interval 5 | 38
prolonged ST segment 5 | 36
small testis 5 | 58
abnormal sleep behavior 4 | 70
abnormal testis morphology 4 | 43
decreased bone mineral density 4 | 126
decreased circulating LDL chol... 4 | 38
decreased circulating aspartat... 4 | 34
decreased circulating insulin ... 4 | 76
decreased mean corpuscular vol... 4 | 79
embryonic growth retardation 4 | 106
improved glucose tolerance 4 | 79
increased lymphocyte cell numb... 4 | 32
increased red blood cell distr... 4 | 34
increased vertical activity 4 | 24
prenatal lethality prior to he... 4 | 87
abnormal coat-hair pigmentatio... 3 | 64
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
abnormal skin morphology 3 | 50
decreased basophil cell number 3 | 16
decreased caudal vertebrae num... 3 | 53
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased mean platelet volume 3 | 25
hemorrhage 3 | 23
hydrometra 3 | 53
increased circulating iron lev... 3 | 30
increased erythrocyte cell num... 3 | 39
increased mean platelet volume 3 | 45
increased neutrophil cell numb... 3 | 46
increased prepulse inhibition 3 | 32
male infertility 3 | 123
small superior vagus ganglion 3 | 74
thin ventricular wall 3 | 24
thrombocytosis 3 | 27
abnormal epididymis morphology 2 | 42
abnormal retinal vasculature m... 2 | 27
abnormal vertebrae morphology 2 | 18
decreased hemoglobin content 2 | 68
decreased pulmonary respirator... 2 | 5
increased circulating amylase ... 2 | 25
increased circulating bilirubi... 2 | 16
increased circulating free fat... 2 | 20
increased circulating phosphat... 2 | 26
increased circulating potassiu... 2 | 29
increased mean corpuscular hem... 2 | 96
pallor 2 | 34

Disease

Carcinoma 515 | 11,192
medulloblastoma, large-cell 390 | 6,086
glioblastoma 378 | 5,635
atypical teratoid / rhabdoid tumor 355 | 4,971
ependymoma 327 | 4,559
ovarian cancer 319 | 8,297
adult high grade glioma 305 | 3,701
osteosarcoma 302 | 7,766
psoriasis 284 | 6,514
Astrocytoma, Pilocytic 265 | 3,006
group 3 medulloblastoma 261 | 4,002
oligodendroglioma 258 | 2,768
astrocytic glioma 219 | 2,530
lung cancer 217 | 4,607
primitive neuroectodermal tumor 216 | 2,957
Schizophrenia 203 | 1,136
Kidney cancer 202 | 2,548
lung carcinoma 173 | 2,755
Breast cancer 170 | 3,469
Cancer 165 | 2,388
malignant mesothelioma 163 | 3,135
subependymal giant cell astrocytoma 159 | 2,230
Pick disease 152 | 1,856
Bipolar Disorder 147 | 646
intraductal papillary-mucinous adenoma (IPMA) 140 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 136 | 3,204
Alzheimer's disease 133 | 640
invasive ductal carcinoma 132 | 2,867
intraductal papillary-mucinous carcinoma (IPMC) 131 | 2,902
pituitary cancer 128 | 1,915
Epilepsy 120 | 775
non-small cell lung cancer 116 | 2,799
Depressive disorder 111 | 401
lung adenocarcinoma 111 | 2,627
Intellectual disability 103 | 998
group 4 medulloblastoma 99 | 1,806
interstitial cystitis 99 | 2,237
Parkinson's disease 98 | 378
pancreatic cancer 98 | 2,322
Mental Depression 92 | 325
diabetes mellitus 91 | 1,683
Seizures 90 | 584
cystic fibrosis 88 | 1,629
Alcoholic Intoxication, Chronic 87 | 283
colon cancer 87 | 1,428
tuberculosis 85 | 1,963
Neurodegenerative disease 84 | 402
Autosomal recessive predisposition 81 | 1,407
breast carcinoma 79 | 1,589
Autistic Disorder 76 | 358
Toxic encephalopathy 74 | 139
ductal carcinoma in situ 74 | 1,686
ulcerative colitis 74 | 1,765
Liver cancer 72 | 589
Major Depressive Disorder 69 | 293
Obesity 69 | 655
astrocytoma 69 | 1,113
adrenocortical carcinoma 62 | 1,385
Neuropathy 61 | 254
Amyotrophic lateral sclerosis 59 | 437
Melanoma 59 | 689
Unipolar Depression 59 | 244
Mood Disorders 58 | 181
Dementia 54 | 172
Down syndrome 54 | 480
pediatric high grade glioma 53 | 1,035
Dull intelligence 51 | 634
Low intelligence 51 | 634
Mental Retardation 51 | 634
Mental deficiency 51 | 634
Poor school performance 51 | 634
Skin cancer 51 | 451
Hypertension 50 | 372
Multiple myeloma 49 | 1,296
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,911
juvenile dermatomyositis 48 | 1,147
Cerebrovascular disease 47 | 223
Multiple Sclerosis 47 | 527
acute quadriplegic myopathy 47 | 1,133
cutaneous lupus erythematosus 47 | 1,016
primary pancreatic ductal adenocarcinoma 47 | 1,071
Atopic dermatitis 46 | 915
Rheumatoid arthritis 46 | 1,156
Cocaine-Related Disorders 44 | 90
spina bifida 44 | 1,053
Attention deficit hyperactivity disorder 43 | 272
Cognitive delay 43 | 596
Global developmental delay 43 | 596
Mental and motor retardation 43 | 596
aldosterone-producing adenoma 43 | 646
progressive supranuclear palsy 43 | 656
Muscle hypotonia 42 | 562
Brain disease 41 | 95
Pain agnosia 41 | 99
Alcohol dependence 40 | 107
dermatomyositis 40 | 941
Heart disease 39 | 288
Asthma 38 | 370
Vascular disease 38 | 294
nasopharyngeal carcinoma 38 | 1,024

Tissue

Endocrine System 686 | 18,159
Nervous System 671 | 16,725
Female tissues 666 | 17,400
Digestive Tract 661 | 17,369
Skin and soft tissues 657 | 17,230
Male tissues 650 | 17,142
Liver and Pancreas 639 | 16,750
Blood and immune system 634 | 16,909
Urinary Tract 628 | 16,678
Respiratory system 619 | 16,393
Cardiovascular System 567 | 15,192

Target Family

Non-IDG 421 | 12,091
Enzyme 95 | 4,145
Ion Channel 57 | 344
Kinase 46 | 634
GPCR 43 | 408
Transporter 23 | 473
Transcription Factor 9 | 1,400
Epigenetic 6 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Neuron projection 701 | 701
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.72615 44.8 147
Cannabinoid receptor 2 CNR2 Tchem GPCR -2.45761 269.7 345
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
AP2-associated protein kinase 1 AAK1 Tchem Kinase -1.28486 18.8 271
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
Dynamin-like 120 kDa protein, mitochondrial OPA1 Tbio Non-IDG -2.51554 307.1 210
Protein ELFN1 ELFN1 Tdark Non-IDG -0.79239 5.92 49
Synaptic vesicle glycoprotein 2A SV2A Tclin Non-IDG -2.60937 395.1 107