Development Level

Tbio 690 | 11,651
Tchem 124 | 1,388
Tclin 97 | 612
Tdark 59 | 6,593

Collection

RFA-RM-18-021 14 | 328
Ion Channel: IDG Consortium (T... 9 | 99
Kinase: IDG Consortium (Comple... 5 | 37
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 51 | 979
abnormal behavior 38 | 298
preweaning lethality, incomple... 36 | 499
decreased total body fat amoun... 20 | 207
hyperactivity 19 | 148
embryonic lethality prior to t... 18 | 278
decreased vertical activity 16 | 208
embryonic lethality prior to o... 15 | 239
increased total body fat amoun... 15 | 134
abnormal bone structure 14 | 187
decreased body weight 14 | 161
increased circulating sodium l... 14 | 71
increased lean body mass 14 | 172
abnormal embryo size 13 | 220
decreased grip strength 13 | 116
decreased bone mineral content 12 | 151
abnormal behavioral response t... 11 | 66
increased bone mineral content 11 | 108
decreased fasted circulating g... 10 | 65
decreased lean body mass 10 | 135
enlarged heart 10 | 210
hypoactivity 10 | 132
impaired glucose tolerance 10 | 75
increased circulating chloride... 10 | 41
increased or absent threshold ... 10 | 101
abnormal gait 9 | 69
decreased circulating choleste... 9 | 93
decreased circulating serum al... 9 | 82
decreased startle reflex 9 | 75
increased fasted circulating g... 9 | 76
short tibia 9 | 97
increased circulating alkaline... 8 | 122
limb grasping 8 | 41
tremors 8 | 39
abnormal heart morphology 7 | 162
abnormal retina morphology 7 | 71
decreased circulating HDL chol... 7 | 68
decreased circulating glucose ... 7 | 126
decreased circulating total pr... 7 | 49
increased heart weight 7 | 62
increased mean corpuscular vol... 7 | 92
increased startle reflex 7 | 112
small testis 7 | 58
abnormal eye morphology 6 | 68
abnormal locomotor behavior 6 | 24
abnormal sleep behavior 6 | 70
decreased bone mineral density 6 | 126
decreased circulating alkaline... 6 | 46
decreased circulating insulin ... 6 | 76
decreased circulating triglyce... 6 | 79
decreased lymphocyte cell numb... 6 | 83
edema 6 | 59
improved glucose tolerance 6 | 79
increased circulating triglyce... 6 | 42
prolonged QT interval 6 | 38
prolonged ST segment 6 | 36
abnormal testis morphology 5 | 43
cataract 5 | 92
convulsive seizures 5 | 13
decreased body length 5 | 101
decreased circulating alanine ... 5 | 47
decreased neutrophil cell numb... 5 | 42
decreased prepulse inhibition 5 | 82
increased prepulse inhibition 5 | 32
male infertility 5 | 123
abnormal coat-hair pigmentatio... 4 | 64
abnormal seminal vesicle morph... 4 | 114
absent startle reflex 4 | 24
decreased circulating LDL chol... 4 | 38
decreased circulating amylase ... 4 | 28
decreased circulating aspartat... 4 | 34
decreased erythrocyte cell num... 4 | 62
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular vol... 4 | 79
embryonic growth retardation 4 | 106
hemorrhage 4 | 23
hydrometra 4 | 53
impaired righting response 4 | 26
increased blood urea nitrogen ... 4 | 48
increased circulating choleste... 4 | 66
increased circulating iron lev... 4 | 30
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular hem... 4 | 96
increased monocyte cell number 4 | 63
increased red blood cell distr... 4 | 34
increased vertical activity 4 | 24
persistence of hyaloid vascula... 4 | 33
prenatal lethality prior to he... 4 | 87
small superior vagus ganglion 4 | 74
abnormal skin morphology 3 | 50
abnormal spleen morphology 3 | 55
decreased hemoglobin content 3 | 68
enlarged kidney 3 | 14
increased body weight 3 | 25
increased circulating calcium ... 3 | 34
increased circulating potassiu... 3 | 29
increased hemoglobin content 3 | 45
increased mean platelet volume 3 | 45
pallor 3 | 34
thrombocytosis 3 | 27

Disease

Carcinoma 710 | 11,493
medulloblastoma, large-cell 511 | 6,241
glioblastoma 486 | 5,792
atypical teratoid / rhabdoid tumor 450 | 5,112
ovarian cancer 435 | 8,520
ependymoma 433 | 4,679
osteosarcoma 425 | 7,950
adult high grade glioma 389 | 3,801
psoriasis 389 | 6,694
group 3 medulloblastoma 340 | 4,104
Astrocytoma, Pilocytic 331 | 3,081
oligodendroglioma 322 | 2,850
lung cancer 292 | 4,740
astrocytic glioma 284 | 2,597
primitive neuroectodermal tumor 283 | 3,035
Kidney cancer 256 | 2,613
Schizophrenia 240 | 1,160
lung carcinoma 231 | 2,843
Breast cancer 219 | 3,578
malignant mesothelioma 215 | 3,232
subependymal giant cell astrocytoma 208 | 2,287
Cancer 201 | 2,499
Pick disease 199 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 182 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 180 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 175 | 2,989
pituitary cancer 173 | 1,972
invasive ductal carcinoma 169 | 2,951
Bipolar Disorder 164 | 666
Alzheimer's disease 155 | 658
non-small cell lung cancer 150 | 2,890
Intellectual disability 149 | 1,016
lung adenocarcinoma 149 | 2,716
Epilepsy 147 | 792
group 4 medulloblastoma 136 | 1,855
pancreatic cancer 134 | 2,398
interstitial cystitis 128 | 2,312
Depressive disorder 122 | 409
Autosomal recessive predisposition 119 | 1,442
Parkinson's disease 115 | 392
colon cancer 113 | 1,478
tuberculosis 112 | 2,010
diabetes mellitus 111 | 1,728
Seizures 110 | 596
cystic fibrosis 107 | 1,696
ulcerative colitis 102 | 1,819
Mental Depression 99 | 333
astrocytoma 99 | 1,146
Liver cancer 98 | 604
breast carcinoma 98 | 1,638
ductal carcinoma in situ 98 | 1,745
Neurodegenerative disease 96 | 414
Obesity 96 | 678
Alcoholic Intoxication, Chronic 95 | 289
Dull intelligence 88 | 645
Low intelligence 88 | 645
Mental Retardation 88 | 645
Mental deficiency 88 | 645
Poor school performance 88 | 645
Autistic Disorder 86 | 364
Toxic encephalopathy 82 | 141
Melanoma 81 | 711
Major Depressive Disorder 76 | 301
adrenocortical carcinoma 74 | 1,428
Multiple myeloma 70 | 1,332
Skin cancer 70 | 469
pediatric high grade glioma 70 | 1,064
Amyotrophic lateral sclerosis 69 | 451
Rheumatoid arthritis 69 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 69 | 1,962
Neuropathy 68 | 261
Cognitive delay 66 | 608
Dementia 66 | 175
Global developmental delay 66 | 608
Mental and motor retardation 66 | 608
Unipolar Depression 66 | 250
Down syndrome 64 | 499
juvenile dermatomyositis 64 | 1,187
Mood Disorders 60 | 184
Muscle hypotonia 59 | 571
spina bifida 59 | 1,074
Hypertension 58 | 396
aldosterone-producing adenoma 58 | 665
Cerebrovascular disease 57 | 238
cutaneous lupus erythematosus 57 | 1,057
primary pancreatic ductal adenocarcinoma 57 | 1,109
acute quadriplegic myopathy 56 | 1,158
progressive supranuclear palsy 56 | 676
Nystagmus 54 | 317
Multiple Sclerosis 53 | 540
dermatomyositis 52 | 966
nasopharyngeal carcinoma 52 | 1,058
Retinitis Pigmentosa 51 | 226
Attention deficit hyperactivity disorder 50 | 278
gastric carcinoma 50 | 807
Atopic dermatitis 49 | 952
Kidney disease 49 | 430
Cocaine-Related Disorders 48 | 92
Cerebellar Ataxia 47 | 304
non primary Sjogren syndrome sicca 47 | 891

Tissue

Endocrine System 945 | 18,159
Nervous System 911 | 16,725
Digestive Tract 909 | 17,369
Female tissues 906 | 17,400
Skin and soft tissues 901 | 17,230
Male tissues 891 | 17,142
Liver and Pancreas 875 | 16,750
Blood and immune system 868 | 16,909
Urinary Tract 857 | 16,678
Respiratory system 841 | 16,393
Cardiovascular System 776 | 15,192

Target Family

Non-IDG 589 | 12,091
Enzyme 141 | 4,145
Ion Channel 65 | 344
Kinase 56 | 634
GPCR 52 | 408
Transporter 32 | 473
Transcription Factor 17 | 1,400
Epigenetic 11 | 242
oGPCR 4 | 421
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

Compartment GO Term

Neuron part 970 | 970
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Contactin-associated protein-like 4 CNTNAP4 Tbio Non-IDG -0.73408 0.00000 148
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Synaptic vesicle 2-related protein SVOP Tdark Non-IDG -0.57678 4.35 90
A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAMTS2 Tbio Enzyme -2.51717 1472.5 133
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Serine/threonine-protein kinase MAK MAK Tchem Kinase -1.20155 15.2 266