Development Level

Tbio 595 | 10,625
Tchem 155 | 1,890
Tclin 92 | 602
Tdark 71 | 7,003

Collection

Eligible Ion Channel Proteins 9 | 117
Eligible non-olfactory GPCR Proteins 8 | 143
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 34 | 633
abnormal behavior 24 | 226
decreased total body fat amoun... 18 | 186
preweaning lethality, incomple... 18 | 260
decreased grip strength 16 | 123
decreased lean body mass 16 | 195
increased or absent threshold ... 13 | 128
abnormal bone structure 12 | 131
embryonic lethality prior to t... 12 | 187
decreased bone mineral content 11 | 157
hyperactivity 11 | 108
increased circulating sodium l... 11 | 71
increased lean body mass 11 | 107
decreased body weight 10 | 174
decreased circulating HDL chol... 9 | 77
embryonic lethality prior to o... 9 | 148
increased mean corpuscular hem... 9 | 93
abnormal embryo size 8 | 112
abnormal gait 8 | 51
decreased circulating choleste... 8 | 85
decreased fasted circulating g... 8 | 49
increased circulating alkaline... 8 | 119
tremors 8 | 34
decreased bone mineral density 7 | 126
decreased circulating alanine ... 7 | 53
decreased circulating alkaline... 7 | 41
decreased prepulse inhibition 7 | 52
enlarged heart 7 | 111
hypoactivity 7 | 89
increased circulating chloride... 7 | 43
increased fasted circulating g... 7 | 68
increased mean corpuscular vol... 7 | 91
abnormal sleep behavior 6 | 63
decreased circulating glucose ... 6 | 121
decreased circulating insulin ... 6 | 75
decreased circulating total pr... 6 | 41
decreased circulating triglyce... 6 | 83
impaired glucose tolerance 6 | 52
improved glucose tolerance 6 | 56
increased bone mineral content 6 | 92
limb grasping 6 | 35
male infertility 6 | 62
short tibia 6 | 82
abnormal behavioral response t... 5 | 52
decreased body length 5 | 108
decreased circulating serum al... 5 | 79
increased blood urea nitrogen ... 5 | 44
increased body weight 5 | 42
increased circulating calcium ... 5 | 32
persistence of hyaloid vascula... 5 | 22
abnormal hindbrain development 4 | 24
abnormal locomotor activation 4 | 26
abnormal neural tube closure 4 | 37
abnormal retina morphology 4 | 100
absent startle reflex 4 | 15
decreased circulating LDL chol... 4 | 37
decreased circulating amylase ... 4 | 24
decreased circulating aspartat... 4 | 27
decreased circulating chloride... 4 | 32
decreased heart weight 4 | 44
decreased mean corpuscular vol... 4 | 50
decreased startle reflex 4 | 48
decreased vertical activity 4 | 22
hemorrhage 4 | 12
increased circulating choleste... 4 | 53
increased circulating iron lev... 4 | 25
increased grip strength 4 | 83
increased heart weight 4 | 37
increased hemoglobin content 4 | 45
increased startle reflex 4 | 38
increased total body fat amoun... 4 | 57
prenatal lethality prior to he... 4 | 64
abnormal QRS complex 3 | 25
abnormal bone mineralization 3 | 55
abnormal coat/hair pigmentatio... 3 | 54
abnormal heart left ventricle ... 3 | 20
abnormal midbrain development 3 | 22
abnormal skin morphology 3 | 23
abnormal spleen morphology 3 | 36
absent pinna reflex 3 | 21
cardiovascular system phenotyp... 3 | 35
decreased hemoglobin content 3 | 53
decreased pulmonary respirator... 3 | 4
decreased rib number 3 | 59
decreased total retina thickne... 3 | 20
impaired righting response 3 | 19
increased circulating HDL chol... 3 | 63
increased circulating potassiu... 3 | 31
increased exploration in new e... 3 | 56
increased mean corpuscular hem... 3 | 25
increased prepulse inhibition 3 | 21
increased rib number 3 | 41
polycystic kidney 3 | 9
straub tail 3 | 26
abnormal epididymis morphology 2 | 31
abnormal optic disc morphology 2 | 10
increased circulating bilirubi... 2 | 16
increased circulating serum al... 2 | 25
increased erythrocyte cell num... 2 | 26
thrombocytosis 2 | 23

Disease

medulloblastoma, large-cell 487 | 6,234
glioblastoma 445 | 5,572
ovarian cancer 402 | 8,484
osteosarcoma 394 | 7,933
psoriasis 373 | 6,685
atypical teratoid / rhabdoid tumor 371 | 4,369
pilocytic astrocytoma 326 | 3,086
oligodendroglioma 318 | 2,849
primitive neuroectodermal tumor 279 | 3,031
pediatric high grade glioma 265 | 2,712
lung cancer 256 | 4,466
ependymoma 223 | 2,514
lung carcinoma 218 | 2,844
Carcinoma 213 | 2,147
astrocytic glioma 213 | 2,241
malignant mesothelioma 206 | 3,162
subependymal giant cell astrocytoma 204 | 2,287
Pick disease 189 | 1,893
Cancer 185 | 2,346
adult high grade glioma 173 | 2,148
Breast cancer 171 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 170 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 167 | 3,289
pituitary cancer 165 | 1,972
astrocytoma 163 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 162 | 2,988
invasive ductal carcinoma 161 | 2,950
medulloblastoma 147 | 1,524
lung adenocarcinoma 142 | 2,713
non-small cell lung cancer 142 | 2,798
Schizophrenia 141 | 501
Alzheimer's disease 138 | 644
group 4 medulloblastoma 135 | 1,875
posterior fossa group A ependymoma 135 | 1,511
group 3 medulloblastoma 128 | 2,254
interstitial cystitis 122 | 2,299
sonic hedgehog group medulloblastoma 118 | 1,482
colon cancer 113 | 1,475
posterior fossa group B ependymoma 110 | 1,530
Parkinson's disease 109 | 364
pancreatic cancer 109 | 2,300
Epilepsy 107 | 346
ulcerative colitis 102 | 2,087
cystic fibrosis 101 | 1,665
diabetes mellitus 101 | 1,663
Neurodegenerative disease 95 | 383
breast carcinoma 94 | 1,614
ductal carcinoma in situ 94 | 1,745
Intellectual disability 85 | 573
atypical teratoid/rhabdoid tumor 85 | 1,095
Obesity 82 | 616
Autistic Disorder 79 | 320
tuberculosis 79 | 1,557
Toxic encephalopathy 76 | 131
adrenocortical carcinoma 69 | 1,427
Bipolar Disorder 66 | 266
Down syndrome 65 | 548
Multiple myeloma 65 | 1,327
Rheumatoid Arthritis 64 | 1,160
Amyotrophic Lateral Sclerosis 63 | 431
Dementia 61 | 129
pancreatic ductal adenocarcinoma liver metastasis 61 | 1,795
juvenile dermatomyositis 60 | 1,189
acute quadriplegic myopathy 58 | 1,157
spina bifida 58 | 1,064
Neuropathy 57 | 210
cutaneous lupus erythematosus 57 | 1,056
primary pancreatic ductal adenocarcinoma 56 | 1,271
Cerebrovascular disease 54 | 231
dermatomyositis 53 | 933
aldosterone-producing adenoma 51 | 664
gastric carcinoma 51 | 832
Atopic dermatitis 50 | 944
Multiple Sclerosis 50 | 498
nasopharyngeal carcinoma 50 | 1,056
Seizures 49 | 95
progressive supranuclear palsy 49 | 674
Cocaine-Related Disorders 46 | 88
Pain agnosia 45 | 99
Hypertension 44 | 287
Alcohol dependence 43 | 107
non primary Sjogren syndrome sicca 43 | 840
Vascular disease 42 | 281
Kidney disease 41 | 396
Major Depressive Disorder 40 | 106
Waldenstrons macroglobulinemia 40 | 765
Brain disease 39 | 83
Duchenne muscular dystrophy 39 | 602
Heart disease 38 | 279
esophageal adenocarcinoma 38 | 737
Asthma 37 | 349
Migraine 37 | 79
Attention deficit hyperactivity disorder 36 | 156
Endometriosis 36 | 535
fibroadenoma 36 | 557
Status Epilepticus 35 | 85
acute myeloid leukemia 35 | 780
Hyperalgesia 34 | 71
Pain 34 | 70
autosomal dominant Emery-Dreifuss muscular dystrophy 34 | 499

Tissue

Nervous System 901 | 18,561
Female tissues 900 | 18,647
Digestive Tract 897 | 18,473
Endocrine System 897 | 18,512
Urinary Tract 895 | 18,444
Liver and Pancreas 887 | 18,136
Skin and soft tissues 885 | 18,115
Cardiovascular System 881 | 17,958
Blood and immune system 875 | 17,995
Male tissues 869 | 17,969
Respiratory system 857 | 17,484

Target Family

Non-IDG 552 | 11,971
Enzyme 130 | 4,146
Ion Channel 62 | 341
GPCR 52 | 406
Kinase 45 | 634
Transporter 32 | 473
Transcription Factor 16 | 1,400
Epigenetic 11 | 242
oGPCR 10 | 421
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

Compartment GO Term

Neuron part 913 | 913
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Protein Smaug homolog 1 SAMD4A Tbio Non-IDG 16.8 58
Stereocilin STRC Tbio Non-IDG 35.9 7
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248