Development Level

Tbio 595 | 10,625
Tchem 155 | 1,890
Tclin 92 | 602
Tdark 71 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 9 | 102
GPCR: IDG Consortium (Targets) 5 | 127
Kinase: IDG Consortium (Complete/Control) 5 | 37
Kinase: IDG Consortium (Targets) 2 | 125

IMPC Phenotype

preweaning lethality, complete... 34 | 633
abnormal behavior 24 | 226
decreased total body fat amoun... 18 | 186
preweaning lethality, incomple... 18 | 260
decreased grip strength 16 | 123
decreased lean body mass 16 | 195
increased or absent threshold ... 13 | 128
abnormal bone structure 12 | 131
embryonic lethality prior to t... 12 | 187
decreased bone mineral content 11 | 157
hyperactivity 11 | 108
increased circulating sodium l... 11 | 71
increased lean body mass 11 | 107
decreased body weight 10 | 174
decreased circulating HDL chol... 9 | 77
embryonic lethality prior to o... 9 | 148
increased mean corpuscular hem... 9 | 93
abnormal embryo size 8 | 112
abnormal gait 8 | 51
decreased circulating choleste... 8 | 85
decreased fasted circulating g... 8 | 49
increased circulating alkaline... 8 | 119
tremors 8 | 34
decreased bone mineral density 7 | 126
decreased circulating alanine ... 7 | 53
decreased circulating alkaline... 7 | 41
decreased prepulse inhibition 7 | 52
enlarged heart 7 | 111
hypoactivity 7 | 89
increased circulating chloride... 7 | 43
increased fasted circulating g... 7 | 68
increased mean corpuscular vol... 7 | 91
abnormal sleep behavior 6 | 63
decreased circulating glucose ... 6 | 121
decreased circulating insulin ... 6 | 75
decreased circulating total pr... 6 | 41
decreased circulating triglyce... 6 | 83
impaired glucose tolerance 6 | 52
improved glucose tolerance 6 | 56
increased bone mineral content 6 | 92
limb grasping 6 | 35
male infertility 6 | 62
short tibia 6 | 82
abnormal behavioral response t... 5 | 52
decreased body length 5 | 108
decreased circulating serum al... 5 | 79
increased blood urea nitrogen ... 5 | 44
increased body weight 5 | 42
increased circulating calcium ... 5 | 32
persistence of hyaloid vascula... 5 | 22
abnormal hindbrain development 4 | 24
abnormal locomotor activation 4 | 26
abnormal neural tube closure 4 | 37
abnormal retina morphology 4 | 100
absent startle reflex 4 | 15
decreased circulating LDL chol... 4 | 37
decreased circulating amylase ... 4 | 24
decreased circulating aspartat... 4 | 27
decreased circulating chloride... 4 | 32
decreased heart weight 4 | 44
decreased mean corpuscular vol... 4 | 50
decreased startle reflex 4 | 48
decreased vertical activity 4 | 22
hemorrhage 4 | 12
increased circulating choleste... 4 | 53
increased circulating iron lev... 4 | 25
increased grip strength 4 | 83
increased heart weight 4 | 37
increased hemoglobin content 4 | 45
increased startle reflex 4 | 38
increased total body fat amoun... 4 | 57
prenatal lethality prior to he... 4 | 64
abnormal QRS complex 3 | 25
abnormal bone mineralization 3 | 55
abnormal coat-hair pigmentatio... 3 | 54
abnormal heart left ventricle ... 3 | 20
abnormal midbrain development 3 | 22
abnormal skin morphology 3 | 23
abnormal spleen morphology 3 | 36
absent pinna reflex 3 | 21
cardiovascular system phenotyp... 3 | 35
decreased hemoglobin content 3 | 53
decreased pulmonary respirator... 3 | 4
decreased rib number 3 | 59
decreased total retina thickne... 3 | 20
impaired righting response 3 | 19
increased circulating HDL chol... 3 | 63
increased circulating potassiu... 3 | 31
increased exploration in new e... 3 | 56
increased mean corpuscular hem... 3 | 25
increased prepulse inhibition 3 | 21
increased rib number 3 | 41
polycystic kidney 3 | 9
straub tail 3 | 26
abnormal epididymis morphology 2 | 31
abnormal optic disc morphology 2 | 10
increased circulating bilirubi... 2 | 16
increased circulating serum al... 2 | 25
increased erythrocyte cell num... 2 | 26
thrombocytosis 2 | 23

Disease

medulloblastoma, large-cell 487 | 6,234
glioblastoma 445 | 5,572
ovarian cancer 403 | 8,491
osteosarcoma 394 | 7,933
psoriasis 373 | 6,685
atypical teratoid / rhabdoid tumor 371 | 4,369
pilocytic astrocytoma 326 | 3,086
oligodendroglioma 318 | 2,849
primitive neuroectodermal tumor 279 | 3,031
pediatric high grade glioma 265 | 2,712
lung cancer 257 | 4,473
ependymoma 223 | 2,514
lung carcinoma 218 | 2,844
Carcinoma 213 | 2,147
astrocytic glioma 213 | 2,241
malignant mesothelioma 206 | 3,163
subependymal giant cell astrocytoma 204 | 2,287
Pick disease 189 | 1,893
Cancer 185 | 2,346
adult high grade glioma 173 | 2,148
Breast cancer 171 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 170 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 167 | 3,289
pituitary cancer 165 | 1,972
astrocytoma 163 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 162 | 2,988
invasive ductal carcinoma 161 | 2,950
medulloblastoma 147 | 1,524
Schizophrenia 142 | 503
lung adenocarcinoma 142 | 2,714
non-small cell lung cancer 142 | 2,798
Alzheimer's disease 138 | 644
group 4 medulloblastoma 135 | 1,875
posterior fossa group A ependymoma 135 | 1,511
group 3 medulloblastoma 128 | 2,254
interstitial cystitis 122 | 2,299
sonic hedgehog group medulloblastoma 118 | 1,482
colon cancer 113 | 1,475
posterior fossa group B ependymoma 110 | 1,530
Parkinson's disease 109 | 364
pancreatic cancer 109 | 2,300
Epilepsy 107 | 346
cystic fibrosis 102 | 1,670
ulcerative colitis 102 | 2,087
diabetes mellitus 101 | 1,663
Neurodegenerative disease 95 | 383
breast carcinoma 94 | 1,614
ductal carcinoma in situ 94 | 1,745
Intellectual disability 85 | 573
atypical teratoid/rhabdoid tumor 85 | 1,095
Obesity 82 | 616
tuberculosis 80 | 1,563
Autistic Disorder 79 | 320
Toxic encephalopathy 76 | 131
adrenocortical carcinoma 69 | 1,427
Bipolar Disorder 66 | 266
Down syndrome 65 | 548
Multiple myeloma 65 | 1,327
Rheumatoid Arthritis 64 | 1,170
Amyotrophic Lateral Sclerosis 63 | 432
Dementia 61 | 129
pancreatic ductal adenocarcinoma liver metastasis 61 | 1,795
juvenile dermatomyositis 60 | 1,189
acute quadriplegic myopathy 58 | 1,157
spina bifida 58 | 1,064
Neuropathy 57 | 210
cutaneous lupus erythematosus 57 | 1,056
primary pancreatic ductal adenocarcinoma 56 | 1,271
Cerebrovascular disease 54 | 231
dermatomyositis 53 | 966
aldosterone-producing adenoma 51 | 664
gastric carcinoma 51 | 832
Atopic dermatitis 50 | 944
Multiple Sclerosis 50 | 498
nasopharyngeal carcinoma 50 | 1,056
Seizures 49 | 95
progressive supranuclear palsy 49 | 674
Cocaine-Related Disorders 46 | 88
Pain agnosia 45 | 99
Hypertension 44 | 293
Alcohol dependence 43 | 107
non primary Sjogren syndrome sicca 43 | 840
Vascular disease 42 | 281
Kidney disease 41 | 397
Major Depressive Disorder 40 | 106
Waldenstrons macroglobulinemia 40 | 764
Brain disease 39 | 84
Duchenne muscular dystrophy 39 | 602
Heart disease 38 | 279
esophageal adenocarcinoma 38 | 737
Asthma 37 | 349
Migraine 37 | 79
Attention deficit hyperactivity disorder 36 | 156
Endometriosis 36 | 535
fibroadenoma 36 | 557
Status Epilepticus 35 | 85
acute myeloid leukemia 35 | 785
Hyperalgesia 34 | 71
Pain 34 | 70
autosomal dominant Emery-Dreifuss muscular dystrophy 34 | 499

Tissue

Nervous System 901 | 18,560
Female tissues 900 | 18,646
Digestive Tract 897 | 18,472
Endocrine System 897 | 18,511
Urinary Tract 895 | 18,443
Liver and Pancreas 887 | 18,135
Skin and soft tissues 885 | 18,114
Cardiovascular System 881 | 17,957
Blood and immune system 875 | 17,994
Male tissues 869 | 17,968
Respiratory system 857 | 17,483

Target Family

Non-IDG 550 | 11,969
Enzyme 130 | 4,146
Ion Channel 62 | 341
GPCR 54 | 408
Kinase 45 | 634
Transporter 32 | 473
Transcription Factor 16 | 1,400
Epigenetic 11 | 242
oGPCR 10 | 421
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

Compartment GO Term

Neuron part 913 | 913
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 1E HTR1E Tchem GPCR -1.54352 34.9 99
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.13194 126.3 290
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.51625 341.8 227
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
SH3 and multiple ankyrin repeat domains protein 1 SHANK1 Tbio Non-IDG -1.52802 34.3 167
Alternative prion protein PRNP Tbio Non-IDG -3.44085 5471.9 0
Serine/threonine-protein kinase LMTK3 LMTK3 Tbio Kinase -1.18725 16.9 129
Serine protease hepsin HPN Tchem Enzyme -2.46640 312.3 106
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.05975 10.9 48