Development Level

Tbio 39 | 11,445
Tclin 12 | 613
Tchem 11 | 1,598
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased basophil cell number 2 | 16
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal hair growth 1 | 10
abnormal joint morphology 1 | 23
abnormal limb morphology 1 | 13
abnormal rib morphology 1 | 10
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
absent startle reflex 1 | 24
brachydactyly 1 | 19
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased circulating alkaline... 1 | 46
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
respiratory system phenotype 1 | 2
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 46 | 11,493
ovarian cancer 29 | 8,520
atypical teratoid / rhabdoid tumor 28 | 5,112
ependymoma 27 | 4,679
medulloblastoma, large-cell 27 | 6,241
glioblastoma 26 | 5,792
psoriasis 26 | 6,694
osteosarcoma 23 | 7,950
Neuropathy 21 | 261
lung cancer 21 | 4,740
Autosomal recessive predisposition 20 | 1,442
Astrocytoma, Pilocytic 19 | 3,081
oligodendroglioma 19 | 2,850
Cancer 18 | 2,499
adult high grade glioma 18 | 3,801
astrocytic glioma 18 | 2,597
pituitary cancer 18 | 1,972
Alzheimer's disease 17 | 658
group 3 medulloblastoma 17 | 4,104
Breast cancer 16 | 3,578
Kidney cancer 16 | 2,613
Schizophrenia 16 | 1,160
malignant mesothelioma 16 | 3,232
Congenital myasthenic syndrome 15 | 25
Neurodegenerative disease 15 | 414
Blepharoptosis 14 | 231
invasive ductal carcinoma 14 | 2,951
primitive neuroectodermal tumor 14 | 3,035
Toxic encephalopathy 13 | 141
Bipolar Disorder 12 | 666
Hypoplastic mandible condyle 12 | 275
Intellectual disability 12 | 1,016
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
Pick disease 12 | 1,894
ductal carcinoma in situ 12 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
tuberculosis 12 | 2,010
Dementia 11 | 175
Muscle hypotonia 11 | 571
Myopathy 11 | 185
Parkinson's disease 11 | 392
colon cancer 11 | 1,478
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
subependymal giant cell astrocytoma 11 | 2,287
Congenital Myasthenic Syndromes, Postsynaptic 10 | 11
Liver cancer 10 | 604
Mental Depression 10 | 333
interstitial cystitis 10 | 2,312
lung carcinoma 10 | 2,843
Amyotrophic lateral sclerosis 9 | 451
Arthrogryposis 9 | 54
Deglutition Disorders 9 | 132
Down syndrome 9 | 499
Epilepsy 9 | 792
Feeding difficulties 9 | 127
Myasthenic Syndromes, Congenital 9 | 16
cutaneous lupus erythematosus 9 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Acquired scoliosis 8 | 281
Byzanthine arch palate 8 | 194
Curvature of spine 8 | 282
Depressive disorder 8 | 409
Dull intelligence 8 | 645
Easy fatigability 8 | 18
Heart failure 8 | 162
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Prenatal onset 8 | 139
Respiratory Insufficiency 8 | 132
Respiratory function loss 8 | 121
Seizures 8 | 596
Tires quickly 8 | 18
breast carcinoma 8 | 1,638
dermatomyositis 8 | 966
pancreatic cancer 8 | 2,398
ulcerative colitis 8 | 1,819
Cerebrovascular disease 7 | 238
Cleft Palate 7 | 271
Duchenne muscular dystrophy 7 | 601
Fetal Growth Retardation 7 | 189
Gowers sign 7 | 24
Gowers sign present 7 | 24
Infantile onset 7 | 238
Multiple pterygium syndrome 7 | 18
Muscular dystrophy 7 | 75
Nerve Degeneration 7 | 121
Orbital separation excessive 7 | 244
Ptosis 7 | 48
Status Epilepticus 7 | 98
Uranostaphyloschisis 7 | 167
acute quadriplegic myopathy 7 | 1,158
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962

Tissue

Skin and soft tissues 63 | 17,230
Digestive Tract 62 | 17,369
Endocrine System 62 | 18,159
Male tissues 62 | 17,142
Female tissues 61 | 17,400
Liver and Pancreas 60 | 16,750
Blood and immune system 59 | 16,909
Urinary Tract 59 | 16,678
Nervous System 58 | 16,725
Cardiovascular System 56 | 15,192
Respiratory system 56 | 16,393

Target Family

Non-IDG 35 | 12,091
Enzyme 14 | 4,145
Ion Channel 8 | 344
Kinase 3 | 634
Transporter 3 | 473
Epigenetic 1 | 242
GPCR 1 | 408

Compartment GO Term

Neuromuscular junction 65 | 65
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proline-rich membrane anchor 1 PRIMA1 Tbio Non-IDG -2.20803 151.5 6
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Putative synaptogyrin-2 like protein N/A Tdark Non-IDG -0.69433 7.83 0
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
E3 ubiquitin-protein ligase PDZRN3 PDZRN3 Tbio Enzyme -1.20019 15.7 71
TBC1 domain family member 24 TBC1D24 Tbio Non-IDG -2.24696 145.0 34
F-BAR and double SH3 domains protein 2 FCHSD2 Tbio Non-IDG -1.56117 35.3 75
F-BAR and double SH3 domains protein 1 FCHSD1 Tdark Non-IDG -0.23145 1.99 81
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436