Development Level

Tbio 28 | 11,445
Tdark 8 | 6,588
Tchem 4 | 1,598

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal nail morphology 1 | 8
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased food intake 1 | 13
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hydrometra 1 | 53
increased body weight 1 | 25
increased circulating iron lev... 1 | 30
increased leukocyte cell numbe... 1 | 47
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Nephronophthisis 36 | 80
Carcinoma 26 | 11,493
Meckel syndrome 24 | 46
Joubert syndrome 23 | 66
ovarian cancer 20 | 8,520
Senior-Loken syndrome 18 | 22
Cystic kidney disease 17 | 26
ependymoma 16 | 4,679
osteosarcoma 15 | 7,950
Autosomal recessive predisposition 14 | 1,442
Polydactyly 14 | 107
Ciliopathy 13 | 71
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Intellectual disability 13 | 1,016
Mental and motor retardation 13 | 608
Retinal Dystrophies 12 | 33
group 3 medulloblastoma 12 | 4,104
Bardet-Biedl syndrome 11 | 51
Nystagmus 11 | 317
Meckel-Gruber syndrome 10 | 13
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
Cerebellar Ataxia 9 | 304
Dull intelligence 9 | 645
Low Vision 9 | 174
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Muscle hypotonia 9 | 571
Poor school performance 9 | 645
Renal dysplasia and retinal aplasia (disorder) 9 | 10
Retinal Degeneration 9 | 106
Visual Impairment 9 | 174
lung cancer 9 | 4,740
Apnea 8 | 45
Biparietal narrowing 8 | 28
Cerebellar vermis hypoplasia 8 | 24
Chronic kidney disease stage 5 8 | 31
Decreased width of the skull 8 | 28
Kidney Diseases 8 | 114
Kidney cancer 8 | 2,613
Long face 8 | 71
Obesity 8 | 678
Retinitis Pigmentosa 8 | 226
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
malignant mesothelioma 8 | 3,232
Caroli disease 7 | 10
Defective or absent horizontal voluntary eye movements 7 | 25
Familial aplasia of the vermis 7 | 19
Fundus dystrophy 7 | 83
Hypertensive disease 7 | 292
Increase in blood pressure 7 | 119
Low-set, posteriorly rotated ears 7 | 110
Molar tooth sign on MRI 7 | 12
Oculomotor apraxia 7 | 25
Oligohydramnios 7 | 52
Short stature 7 | 531
primitive neuroectodermal tumor 7 | 3,035
Abnormality of retinal pigmentation 6 | 111
Asphyxiating thoracic dystrophy 6 | 44
Autosomal recessive polycystic kidney disease 6 | 41
Decreased visual acuity, progressive 6 | 36
Leber congenital amaurosis 6 | 69
Maternal oligohydramnios 6 | 31
Multicystic Dysplastic Kidney 6 | 52
Premature Menopause 6 | 31
Progressive visual loss 6 | 36
Retinal pigment epithelial abnormality 6 | 111
Situs Inversus 6 | 65
Ulnar polydactyly of fingers 6 | 47
chronic rhinosinusitis 6 | 512
oligodendroglioma 6 | 2,850
Arima syndrome 5 | 7
Autosomal dominant polycystic kidney disease 5 | 31
Bardet-Biedl syndrome 1 5 | 22
Bile duct proliferation 5 | 9
Blepharoptosis 5 | 231
Cataract 5 | 297
Coloboma of iris 5 | 38
Congenital cerebral hernia 5 | 21
Electroretinogram abnormal 5 | 95
Gait abnormality 5 | 135
Kidney damage 5 | 25
Lens Opacities 5 | 231
Nephronophthisis, familial juvenile 5 | 5
Orofaciodigital syndrome 5 | 21
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
Corneal diameter decreased 4 | 47
Depressed nasal ridge 4 | 51
Full cheeks 4 | 50
Hypoplastic mandible condyle 4 | 275
Sclerocornea 4 | 29
Sloping forehead 4 | 46
Talipes 4 | 20

Tissue

Blood and immune system 40 | 16,909
Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Liver and Pancreas 40 | 16,750
Male tissues 40 | 17,142
Skin and soft tissues 40 | 17,230
Female tissues 39 | 17,400
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Urinary Tract 39 | 16,678
Cardiovascular System 38 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 5 | 634
Enzyme 4 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344

Compartment GO Term

NPHP complex 40 | 40
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 17 TMEM17 Tbio Non-IDG 0.61 0.56 52
Coiled-coil domain-containing protein 28B CCDC28B Tbio Non-IDG -0.62521 3.91 60
Doublecortin domain-containing protein 2 DCDC2 Tbio Non-IDG -1.71331 52.4 209
Protein CC2D2B CC2D2B Tdark Non-IDG 1.04 0.06 18
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Neurexophilin-4 NXPH4 Tbio Non-IDG -1.16543 15.7 125
Coiled-coil and C2 domain-containing protein 2A CC2D2A Tbio Non-IDG -1.23748 18.2 17
Transmembrane protein 80 TMEM80 Tdark Non-IDG -0.12285 1.23 68