Development Level

Tbio 26 | 10,625
Tdark 8 | 7,003
Tchem 5 | 1,890

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal cervical vertebrae mo... 1 | 4
abnormal nail morphology 1 | 7
abnormal response to tactile s... 1 | 16
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
embryonic lethality prior to t... 1 | 187
enlarged uterus 1 | 3
hydrometra 1 | 13
increased B cell number 1 | 23
increased body weight 1 | 42
increased circulating iron lev... 1 | 25
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased total body fat amoun... 1 | 57
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
small superior vagus ganglion 1 | 20
small testis 1 | 37

Disease

Nephronophthisis 36 | 74
Joubert syndrome 24 | 61
Meckel syndrome 24 | 48
ovarian cancer 21 | 8,484
Senior-Loken syndrome 18 | 21
Cystic kidney disease 15 | 25
osteosarcoma 14 | 7,933
Bardet-Biedl Syndrome 13 | 40
Polydactyly 13 | 93
Ciliopathy 12 | 57
posterior fossa group B ependymoma 12 | 1,530
medulloblastoma, large-cell 10 | 6,234
Meckel-Gruber syndrome 9 | 15
Renal dysplasia and retinal aplasia (disorder) 9 | 10
lung cancer 9 | 4,466
psoriasis 9 | 6,685
Retinitis pigmentosa 8 | 153
glioblastoma 8 | 5,572
group 3 medulloblastoma 8 | 2,254
malignant mesothelioma 8 | 3,162
Asphyxiating thoracic dystrophy 7 | 32
Fundus dystrophy 7 | 77
Obesity 7 | 616
primitive neuroectodermal tumor 7 | 3,031
Carcinoma 6 | 2,147
Caroli disease 6 | 7
Intellectual disability 6 | 573
Leber congenital amaurosis 6 | 72
chronic rhinosinusitis 6 | 512
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
oligodendroglioma 6 | 2,849
Familial aplasia of the vermis 5 | 8
Kidney Diseases 5 | 86
Pick disease 5 | 1,893
Polycystic kidney disease 5 | 54
Situs Inversus 5 | 48
astrocytic glioma 5 | 2,241
atypical teratoid/rhabdoid tumor 5 | 1,095
ependymoma 5 | 2,514
invasive ductal carcinoma 5 | 2,950
pediatric high grade glioma 5 | 2,712
Coloboma 4 | 51
Hydrolethalus syndrome 4 | 128
Orofaciodigital syndrome 4 | 19
atypical teratoid / rhabdoid tumor 4 | 4,369
lung adenocarcinoma 4 | 2,713
non primary Sjogren syndrome sicca 4 | 840
pilocytic astrocytoma 4 | 3,086
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 674
renal-hepatic-pancreatic dysplasia 4 | 8
sonic hedgehog group medulloblastoma 4 | 1,482
Blindness 3 | 84
Breast cancer 3 | 3,094
COACH syndrome 3 | 4
Cogan syndrome 3 | 4
Cystic Kidney Diseases 3 | 6
Kidney disease 3 | 396
Retinal Degeneration 3 | 49
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
astrocytoma 3 | 1,493
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,665
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung carcinoma 3 | 2,844
tuberculosis 3 | 1,557
Acrofacial dysostosis 2 | 8
Attention deficit hyperactivity disorder 2 | 156
Autosomal Recessive Polycystic Kidney Disease 2 | 5
Cerebellar Diseases 2 | 6
Choledochal cyst 2 | 3
Cone dystrophy 2 | 57
Congenital nystagmus 2 | 26
Ellis-Van Creveld syndrome 2 | 18
End stage renal failure 2 | 5
Familial juvenile hyperuricemic nephropathy 2 | 6
Jeune thoracic dystrophy 2 | 9
Liver Cirrhosis 2 | 101
Schizophrenia 2 | 501
Sensenbrenner syndrome 2 | 15
cone-rod dystrophy 2 | 56
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,875
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
primary pancreatic ductal adenocarcinoma 2 | 1,271
urothelial carcinoma 2 | 318
Cholangitis 1 | 20
Dyslexia 1 | 36
Kidney cancer 1 | 118
Obstructive sleep apnea 1 | 28
Oligohydramnios 1 | 18
Otitis externa 1 | 9
Specific language impairment 1 | 31
West Nile encephalitis 1 | 8

Tissue

Blood and immune system 39 | 17,995
Cardiovascular System 39 | 17,958
Digestive Tract 39 | 18,473
Endocrine System 39 | 18,512
Female tissues 39 | 18,647
Liver and Pancreas 39 | 18,136
Male tissues 39 | 17,969
Nervous System 39 | 18,561
Respiratory system 39 | 17,484
Skin and soft tissues 39 | 18,115
Urinary Tract 39 | 18,444

Target Family

Non-IDG 28 | 11,971
Kinase 5 | 634
Enzyme 4 | 4,146
Transcription Factor 2 | 1,400

Compartment GO Term

NPHP complex 39 | 39
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein GLIS2 GLIS2 Tbio Transcription Factor -1.86726 74.7 85
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48
Nephrocystin-1 NPHP1 Tbio Non-IDG -1.70748 50.8 88
Cyclin-dependent kinase-like 3 CDKL3 Tchem Kinase -0.54794 4.96 138
Cyclin-dependent kinase-like 1 CDKL1 Tchem Kinase -0.66241 5.41 233
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.29586 19.6 50
Transmembrane protein 17 TMEM17 Tbio Non-IDG 1.11 0.06 44
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.58209 3.56 33