Development Level

Tbio 26 | 11,178
Tdark 8 | 6,569
Tchem 5 | 1,885

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal nail morphology 1 | 8
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased food intake 1 | 13
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hydrometra 1 | 53
increased body weight 1 | 25
increased circulating iron lev... 1 | 30
increased leukocyte cell numbe... 1 | 47
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Nephronophthisis 35 | 79
Carcinoma 26 | 11,192
Meckel syndrome 24 | 46
Joubert syndrome 23 | 66
ovarian cancer 19 | 8,297
Senior-Loken syndrome 18 | 22
Cystic kidney disease 16 | 25
ependymoma 15 | 4,559
osteosarcoma 15 | 7,766
Autosomal recessive predisposition 14 | 1,407
Polydactyly 14 | 106
Ciliopathy 13 | 71
Cognitive delay 13 | 596
Global developmental delay 13 | 596
Intellectual disability 13 | 998
Mental and motor retardation 13 | 596
Retinal Dystrophies 12 | 32
group 3 medulloblastoma 12 | 4,002
Bardet-Biedl syndrome 11 | 51
Nystagmus 11 | 309
Meckel-Gruber syndrome 10 | 13
medulloblastoma, large-cell 10 | 6,086
psoriasis 10 | 6,514
Cerebellar Ataxia 9 | 302
Dull intelligence 9 | 634
Low Vision 9 | 167
Low intelligence 9 | 634
Mental Retardation 9 | 634
Mental deficiency 9 | 634
Muscle hypotonia 9 | 562
Poor school performance 9 | 634
Renal dysplasia and retinal aplasia (disorder) 9 | 10
Retinal Degeneration 9 | 103
Visual Impairment 9 | 167
lung cancer 9 | 4,607
Apnea 8 | 45
Biparietal narrowing 8 | 28
Cerebellar vermis hypoplasia 8 | 24
Chronic kidney disease stage 5 8 | 31
Decreased width of the skull 8 | 28
Kidney cancer 8 | 2,548
Long face 8 | 71
Obesity 8 | 655
Retinitis Pigmentosa 8 | 223
atypical teratoid / rhabdoid tumor 8 | 4,971
glioblastoma 8 | 5,635
malignant mesothelioma 8 | 3,135
Defective or absent horizontal voluntary eye movements 7 | 24
Familial aplasia of the vermis 7 | 19
Fundus dystrophy 7 | 80
Hypertensive disease 7 | 278
Increase in blood pressure 7 | 118
Kidney Diseases 7 | 110
Low-set, posteriorly rotated ears 7 | 109
Molar tooth sign on MRI 7 | 12
Oculomotor apraxia 7 | 24
Oligohydramnios 7 | 50
Short stature 7 | 514
primitive neuroectodermal tumor 7 | 2,957
Abnormality of retinal pigmentation 6 | 109
Asphyxiating thoracic dystrophy 6 | 44
Autosomal recessive polycystic kidney disease 6 | 41
Caroli disease 6 | 9
Decreased visual acuity, progressive 6 | 35
Leber congenital amaurosis 6 | 68
Maternal oligohydramnios 6 | 29
Multicystic Dysplastic Kidney 6 | 51
Premature Menopause 6 | 29
Progressive visual loss 6 | 35
Retinal pigment epithelial abnormality 6 | 109
Situs Inversus 6 | 61
Ulnar polydactyly of fingers 6 | 46
chronic rhinosinusitis 6 | 505
Arima syndrome 5 | 7
Autosomal dominant polycystic kidney disease 5 | 30
Bardet-Biedl syndrome 1 5 | 22
Bile duct proliferation 5 | 9
Blepharoptosis 5 | 229
Cataract 5 | 290
Coloboma of iris 5 | 37
Congenital cerebral hernia 5 | 20
Electroretinogram abnormal 5 | 94
Gait abnormality 5 | 129
Kidney damage 5 | 25
Lens Opacities 5 | 227
Orofaciodigital syndrome 5 | 21
Pick disease 5 | 1,856
astrocytic glioma 5 | 2,530
invasive ductal carcinoma 5 | 2,867
oligodendroglioma 5 | 2,768
Chubby cheeks 4 | 49
Corneal diameter decreased 4 | 46
Depressed nasal ridge 4 | 48
Feeding difficulties in infancy 4 | 174
Full cheeks 4 | 49
Hypoplastic mandible condyle 4 | 273
Postaxial foot polydactyly 4 | 12
Sclerocornea 4 | 29
Sloping forehead 4 | 46
Talipes 4 | 20

Tissue

Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Skin and soft tissues 39 | 17,230
Female tissues 38 | 17,400
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Urinary Tract 38 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 5 | 634
Enzyme 4 | 4,145
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

Compartment GO Term

NPHP complex 39 | 39
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 423 ZNF423 Tbio Transcription Factor -1.62303 45.3 77
Transmembrane protein 216 TMEM216 Tbio Non-IDG -1.05847 10.9 0
Transmembrane protein 80 TMEM80 Tdark Non-IDG -0.12285 1.23 68
Coiled-coil and C2 domain-containing protein 2A CC2D2A Tbio Non-IDG -1.23748 18.2 17
Polycystic kidney disease and receptor for egg jelly-related protein PKDREJ Tdark Ion Channel -3.42941 2602.1 26
Serologically defined colon cancer antigen 8 SDCCAG8 Tbio Non-IDG -1.14555 14.3 182
Serine/threonine-protein kinase Nek8 NEK8 Tbio Kinase -1.71536 50.9 225
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 RPGRIP1 Tbio Enzyme -1.69109 46.2 64
Ankyrin repeat and SAM domain-containing protein 6 ANKS6 Tbio Non-IDG -0.91541 9.61 90
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59