Development Level

Tbio 13 | 11,445
Tchem 8 | 1,598
Tclin 4 | 613

IMPC Phenotype

decreased lymphocyte cell numb... 2 | 83
increased neutrophil cell numb... 2 | 46
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
enlarged cecum 1 | 5
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

lung cancer 19 | 4,740
psoriasis 19 | 6,694
Arthritis 16 | 290
lung carcinoma 16 | 2,843
Cancer 15 | 2,499
Carcinoma 15 | 11,493
malignant mesothelioma 15 | 3,232
ovarian cancer 15 | 8,520
Inflammatory bowel disease 14 | 151
cystic fibrosis 14 | 1,696
osteosarcoma 14 | 7,950
tuberculosis 14 | 2,010
Astrocytoma, Pilocytic 13 | 3,081
glioblastoma 13 | 5,792
non-small cell lung cancer 13 | 2,890
subependymal giant cell astrocytoma 12 | 2,287
ulcerative colitis 12 | 1,819
Peritonitis 11 | 43
Pneumonia 11 | 174
diabetes mellitus 11 | 1,728
interstitial cystitis 11 | 2,312
invasive ductal carcinoma 11 | 2,951
Asthma 10 | 385
Dermatitis 10 | 157
Hypersensitivity reaction type II disease 10 | 253
Obesity 10 | 678
Rheumatoid arthritis 10 | 1,191
medulloblastoma, large-cell 10 | 6,241
pancreatic cancer 10 | 2,398
Inflammation 9 | 120
Kidney disease 9 | 430
Multiple Sclerosis 9 | 540
cutaneous lupus erythematosus 9 | 1,057
Bipolar Disorder 8 | 666
Liver Cirrhosis, Experimental 8 | 769
Meningitis 8 | 67
Muckle-Wells syndrome 8 | 12
adult high grade glioma 8 | 3,801
group 3 medulloblastoma 8 | 4,104
lung adenocarcinoma 8 | 2,716
Allergic hypersensitivity disease 7 | 126
Arthritis, Rheumatoid 7 | 174
Atherosclerosis 7 | 291
Brain Injuries 7 | 65
Breast cancer 7 | 3,578
Gout 7 | 106
Neoplasm Invasiveness 7 | 161
Salmonellosis 7 | 42
Schizophrenia 7 | 1,160
Vasculitis 7 | 80
atypical teratoid / rhabdoid tumor 7 | 5,112
periodontitis 7 | 293
Amyloidosis 6 | 67
Arthropathy 6 | 43
Common cold 6 | 67
Coronary artery disease 6 | 268
Diarrhea 6 | 253
Endometriosis 6 | 540
Exanthem 6 | 37
Familial cold autoinflammatory syndrome 6 | 10
Fever 6 | 138
Gastritis 6 | 47
Hypersensitivity 6 | 63
Hypertension 6 | 396
Influenza 6 | 142
Leishmaniasis 6 | 47
Liver disease 6 | 237
Lung disease 6 | 142
Malaria 6 | 160
Pancreatitis 6 | 123
Reperfusion Injury 6 | 86
Urticaria 6 | 67
pituitary cancer 6 | 1,972
sarcoidosis 6 | 370
Ankylosing spondylitis 5 | 140
Brain Ischemia 5 | 110
Cerebrovascular disease 5 | 238
Depressive disorder 5 | 409
Dermatologic disorders 5 | 93
Heart disease 5 | 306
Keratitis 5 | 62
Lung Neoplasms 5 | 232
Mastitis 5 | 48
Mental Depression 5 | 333
Necrosis 5 | 53
Neurodegenerative disease 5 | 414
Otitis Media 5 | 52
Perinatal necrotizing enterocolitis 5 | 21
Prostatic Neoplasms 5 | 495
Pulmonary Fibrosis 5 | 106
Skin Diseases 5 | 71
Stomach Neoplasms 5 | 300
Vascular disease 5 | 319
hepatocellular carcinoma 5 | 547
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
mucosa-associated lymphoid tissue lymphoma 5 | 484
pancreatic carcinoma 5 | 562
primary Sjogren syndrome 5 | 735

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 5 | 4,145
Ion Channel 1 | 344

Compartment GO Term

NLRP3 inflammasome complex 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Pyrin MEFV Tbio Non-IDG -3.02735 980.3 176
Caspase-4 CASP4 Tchem Enzyme -2.19377 147.3 520
Interferon-inducible protein AIM2 AIM2 Tbio Non-IDG -2.17906 165.7 439
Cathepsin B CTSB Tchem Enzyme -3.72723 5011.5 448
NACHT, LRR and PYD domains-containing protein 1 NLRP1 Tbio Non-IDG -2.03558 116.5 183
Gasdermin-D GSDMD Tbio Non-IDG -1.55687 34.2 87
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
Interleukin-33 IL33 Tbio Non-IDG -2.86989 870.0 754
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672