Development Level

Tbio 76 | 11,445
Tchem 60 | 1,598
Tclin 20 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 5 | 499
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
increased neutrophil cell numb... 4 | 46
short tibia 4 | 97
decreased circulating creatini... 3 | 39
decreased mean corpuscular vol... 3 | 79
enlarged heart 3 | 210
increased lymphocyte cell numb... 3 | 32
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
abnormal midbrain development 2 | 20
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
decreased circulating insulin ... 2 | 76
decreased circulating sodium l... 2 | 22
decreased lymphocyte cell numb... 2 | 83
decreased monocyte cell number 2 | 8
embryonic growth retardation 2 | 106
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating free fat... 2 | 20
increased eosinophil cell numb... 2 | 11
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent seminal vesicle 1 | 4
absent testes 1 | 6
absent vibrissae 1 | 12
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased thermal nociceptive ... 1 | 2
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased large unstained cell... 1 | 5
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
small seminal vesicle 1 | 10
small testis 1 | 58
small uterus 1 | 3
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Cancer 131 | 2,499
psoriasis 104 | 6,694
Carcinoma 101 | 11,493
ovarian cancer 94 | 8,520
lung cancer 88 | 4,740
glioblastoma 81 | 5,792
osteosarcoma 69 | 7,950
tuberculosis 67 | 2,010
diabetes mellitus 64 | 1,728
Arthritis 63 | 290
lung carcinoma 63 | 2,843
malignant mesothelioma 58 | 3,232
ulcerative colitis 58 | 1,819
Asthma 55 | 385
interstitial cystitis 52 | 2,312
medulloblastoma, large-cell 52 | 6,241
Rheumatoid arthritis 51 | 1,191
Kidney disease 49 | 430
Multiple Sclerosis 49 | 540
Inflammatory bowel disease 48 | 151
Lung disease 48 | 142
adult high grade glioma 48 | 3,801
ependymoma 48 | 4,679
Hypersensitivity reaction type II disease 46 | 253
atypical teratoid / rhabdoid tumor 46 | 5,112
Breast cancer 45 | 3,578
Schizophrenia 45 | 1,160
cystic fibrosis 45 | 1,696
Vascular disease 44 | 319
Astrocytoma, Pilocytic 41 | 3,081
subependymal giant cell astrocytoma 41 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
Breast Neoplasms 39 | 445
Mammary Neoplasms 39 | 425
pancreatic cancer 39 | 2,398
Atherosclerosis 38 | 291
Obesity 38 | 678
non-small cell lung cancer 38 | 2,890
cutaneous lupus erythematosus 37 | 1,057
Dermatitis 36 | 157
Pneumonia 36 | 174
Brain Ischemia 35 | 110
Heart disease 35 | 306
Inflammation 35 | 120
Prostatic Neoplasms 35 | 495
Lung Neoplasms 34 | 232
invasive ductal carcinoma 34 | 2,951
Influenza 33 | 142
Reperfusion Injury 32 | 86
Hypertension 31 | 396
Liver Cirrhosis, Experimental 31 | 769
Liver disease 31 | 237
lung adenocarcinoma 31 | 2,716
pituitary cancer 31 | 1,972
Bipolar Disorder 30 | 666
Coronary artery disease 29 | 268
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
Malaria 28 | 160
periodontitis 28 | 293
Anemia 27 | 365
juvenile dermatomyositis 27 | 1,187
primitive neuroectodermal tumor 27 | 3,035
Allergic hypersensitivity disease 26 | 126
Alzheimer's disease 26 | 658
Kidney cancer 26 | 2,613
Stomach Neoplasms 26 | 300
astrocytoma 26 | 1,146
group 3 medulloblastoma 26 | 4,104
oligodendroglioma 26 | 2,850
Arthritis, Rheumatoid 25 | 174
Autosomal recessive predisposition 25 | 1,442
Brain Injuries 25 | 65
Carcinoma, Hepatocellular 25 | 228
Liver carcinoma 25 | 240
Multiple myeloma 25 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
Cerebrovascular disease 24 | 238
Hypertensive disease 24 | 292
Atopic dermatitis 23 | 952
Leishmaniasis 23 | 47
Colonic Neoplasms 22 | 142
Diabetes Mellitus, Experimental 22 | 108
Eye disease 22 | 62
Hyperglycemia 22 | 137
Major Depressive Disorder 22 | 301
Neoplasm Metastasis 22 | 168
Endometriosis 21 | 540
Human immunodeficiency virus infectious disease 21 | 138
Mental Depression 21 | 333
Osteoporosis 21 | 363
acute quadriplegic myopathy 21 | 1,158
breast carcinoma 21 | 1,638
primary pancreatic ductal adenocarcinoma 21 | 1,109
sarcoidosis 21 | 370
Depressive disorder 20 | 409
Hypereosinophilic syndrome 20 | 71
Myocardial Ischemia 20 | 169
Vasculitis 20 | 80
gastric carcinoma 20 | 807
hepatocellular carcinoma 20 | 547

Tissue

Blood and immune system 156 | 16,909
Digestive Tract 154 | 17,369
Liver and Pancreas 154 | 16,750
Male tissues 154 | 17,142
Skin and soft tissues 154 | 17,230
Urinary Tract 153 | 16,678
Female tissues 152 | 17,400
Respiratory system 152 | 16,393
Endocrine System 151 | 18,159
Nervous System 147 | 16,725
Cardiovascular System 142 | 15,192

Target Family

Non-IDG 86 | 12,091
Transcription Factor 23 | 1,400
Kinase 22 | 634
Enzyme 19 | 4,145
Nuclear Receptor 4 | 48
Epigenetic 2 | 242

Compartment GO Term

NF-kappaB complex 156 | 156
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Mitogen-activated protein kinase kinase kinase kinase 4 MAP4K4 Tchem Kinase -2.19064 152.6 547
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
NF-kappa-B inhibitor zeta NFKBIZ Tbio Non-IDG -2.14151 143.2 111
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369