Development Level

Tbio 28 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal bone structure 2 | 187
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal motor learning 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 28 | 11,493
Kidney cancer 21 | 2,613
psoriasis 19 | 6,694
Breast cancer 15 | 3,578
acute quadriplegic myopathy 14 | 1,158
Melanoma 11 | 711
Skin cancer 11 | 469
glioblastoma 11 | 5,792
lung adenocarcinoma 11 | 2,716
ovarian cancer 11 | 8,520
osteosarcoma 10 | 7,950
Distal arthrogryposis 9 | 42
Liver cancer 9 | 604
atypical teratoid / rhabdoid tumor 9 | 5,112
colon cancer 9 | 1,478
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
Duchenne muscular dystrophy 8 | 601
Endometrial cancer 8 | 311
adult high grade glioma 8 | 3,801
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung carcinoma 8 | 2,843
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
Myopathy 7 | 185
Primary cutaneous amyloidosis 7 | 29
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
Hypertrophic Cardiomyopathy 6 | 117
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
breast carcinoma 6 | 1,638
group 3 medulloblastoma 6 | 4,104
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
juvenile dermatomyositis 6 | 1,187
Amyotrophic lateral sclerosis 5 | 451
Becker muscular dystrophy 5 | 191
Cardiomyopathy 5 | 116
Dilated cardiomyopathy 5 | 56
Heart disease 5 | 306
Pick disease 5 | 1,894
cystic fibrosis 5 | 1,696
ependymoma 5 | 4,679
ulcerative colitis 5 | 1,819
Amyloidosis 4 | 67
Arthrogryposis 4 | 54
Blepharoptosis 4 | 231
Byzanthine arch palate 4 | 194
Cardiomyopathy, Dilated 4 | 83
Cerebrovascular disease 4 | 238
Epilepsy 4 | 792
Familial isolated dilated cardiomyopathy 4 | 41
Generalized muscle weakness 4 | 57
Hypertension 4 | 396
Kidney disease 4 | 430
LEFT VENTRICULAR NONCOMPACTION 10 4 | 40
LEFT VENTRICULAR NONCOMPACTION 8 4 | 40
MYH-9 related disease 4 | 12
Ophthalmoplegia 4 | 106
Pertussis 4 | 20
Proximal muscle weakness 4 | 47
Proximal neurogenic muscle weakness 4 | 47
Schizophrenia 4 | 1,160
limb girdle muscular dystrophy 2A 4 | 213
subependymal giant cell astrocytoma 4 | 2,287
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Bell Palsy 3 | 58
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Chest Pain 3 | 38
Conduction disorder of the heart 3 | 79
Congestive heart failure 3 | 113
Coronary artery disease 3 | 268
Curvature of spine 3 | 282
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Facial Paresis 3 | 59
Facial muscle weakness of muscles innervated by CN VII 3 | 58
Infantile onset 3 | 238
Long QT syndrome 1 3 | 20
Myocardial Infarction 3 | 151
Polyhydramnios 3 | 108
Sporotrichosis 3 | 10
Toxic encephalopathy 3 | 141
Ventricular arrhythmia 3 | 27
adrenocortical carcinoma 3 | 1,428
hepatocellular carcinoma 3 | 547
non diabetic and post-ischemic heart failure 3 | 200
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 416

Tissue

Endocrine System 32 | 18,159
Skin and soft tissues 32 | 17,230
Digestive Tract 31 | 17,369
Male tissues 30 | 17,142
Blood and immune system 29 | 16,909
Cardiovascular System 29 | 15,192
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Urinary Tract 27 | 16,678
Nervous System 26 | 16,725
Respiratory system 26 | 16,393

Target Family

Non-IDG 29 | 12,091
Kinase 3 | 634

Compartment GO Term

Myosin filament 32 | 32
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin, gamma-enteric smooth muscle ACTG2 Tbio Non-IDG -1.98240 92.4 212
Myosin-15 MYH15 Tbio Non-IDG -0.95780 9.01 40
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Protein unc-45 homolog B UNC45B Tbio Non-IDG -1.54873 42.8 123
Titin TTN Tbio Kinase -3.24415 1743.0 123
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Myosin-8 MYH8 Tbio Non-IDG -1.71003 48.7 39