Development Level

Tbio 43 | 11,445
Tdark 6 | 6,588
Tchem 5 | 1,598
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
decreased grip strength 2 | 116
edema 2 | 59
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal heart morphology 1 | 162
abnormal motor learning 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

Carcinoma 46 | 11,493
Kidney cancer 28 | 2,613
osteosarcoma 28 | 7,950
ovarian cancer 27 | 8,520
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 22 | 5,112
medulloblastoma, large-cell 22 | 6,241
glioblastoma 20 | 5,792
Breast cancer 18 | 3,578
acute quadriplegic myopathy 16 | 1,158
ependymoma 16 | 4,679
lung carcinoma 15 | 2,843
Cancer 14 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
adult high grade glioma 12 | 3,801
diabetes mellitus 12 | 1,728
lung adenocarcinoma 12 | 2,716
lung cancer 12 | 4,740
malignant mesothelioma 12 | 3,232
Skin cancer 11 | 469
breast carcinoma 11 | 1,638
group 4 medulloblastoma 11 | 1,855
pancreatic cancer 11 | 2,398
subependymal giant cell astrocytoma 11 | 2,287
Melanoma 10 | 711
invasive ductal carcinoma 10 | 2,951
Duchenne muscular dystrophy 9 | 601
Hypertrophic Cardiomyopathy 9 | 117
Liver cancer 9 | 604
astrocytic glioma 9 | 2,597
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Distal arthrogryposis 8 | 42
Hypertension 8 | 396
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
juvenile dermatomyositis 8 | 1,187
pediatric high grade glioma 8 | 1,064
Cerebrovascular disease 7 | 238
Dilated cardiomyopathy 7 | 56
Heart disease 7 | 306
Myopathy 7 | 185
Primary cutaneous amyloidosis 7 | 29
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
ulcerative colitis 7 | 1,819
Amyotrophic lateral sclerosis 6 | 451
Becker muscular dystrophy 6 | 191
Cardiomyopathy 6 | 116
Endometrial cancer 6 | 311
Kidney disease 6 | 430
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
cystic fibrosis 6 | 1,696
limb girdle muscular dystrophy 2A 6 | 213
Amyloidosis 5 | 67
Cardiomyopathy, Dilated 5 | 83
Familial isolated dilated cardiomyopathy 5 | 41
LEFT VENTRICULAR NONCOMPACTION 10 5 | 40
LEFT VENTRICULAR NONCOMPACTION 8 5 | 40
Schizophrenia 5 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer's disease 4 | 658
Blepharoptosis 4 | 231
Cardiomyopathy, Familial Hypertrophic, 1 4 | 6
Epilepsy 4 | 792
Focal glomerulosclerosis 4 | 37
Glomerulosclerosis, Focal Segmental 4 | 28
Impotence 4 | 42
MYH-9 related disease 4 | 12
Neoplasm Invasiveness 4 | 161
Ophthalmoplegia 4 | 106
Pertussis 4 | 20
Proteinuria 4 | 144
Rheumatoid arthritis 4 | 1,191
Sensorineural hearing loss 4 | 106
dermatomyositis 4 | 966
medulloblastoma 4 | 720
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Arthrogryposis 3 | 54
Byzanthine arch palate 3 | 194
Coronary artery disease 3 | 268
Generalized muscle weakness 3 | 57
Glaucoma 3 | 239
Polycystic ovary syndrome 3 | 360
Proximal muscle weakness 3 | 47
Proximal neurogenic muscle weakness 3 | 47
Toxic encephalopathy 3 | 141
Ventricular arrhythmia 3 | 27
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
hepatocellular carcinoma 3 | 547
hereditary spastic paraplegia 3 | 318

Tissue

Endocrine System 59 | 18,159
Digestive Tract 58 | 17,369
Skin and soft tissues 58 | 17,230
Male tissues 56 | 17,142
Blood and immune system 55 | 16,909
Urinary Tract 55 | 16,678
Cardiovascular System 54 | 15,192
Female tissues 54 | 17,400
Nervous System 54 | 16,725
Liver and Pancreas 53 | 16,750
Respiratory system 50 | 16,393

Target Family

Non-IDG 46 | 12,091
Kinase 7 | 634
Enzyme 5 | 4,145
Transporter 1 | 473

Compartment GO Term

Myosin II complex 59 | 59
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WD and tetratricopeptide repeats protein 1 WDTC1 Tbio Non-IDG -4.42806 25979.1 103
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0
Calmodulin-1 CALM3 Tclin Non-IDG -3.59093 5859.5 0
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Myomesin-2 MYOM2 Tbio Non-IDG -3.36742 2270.3 100
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Titin TTN Tbio Kinase -3.24415 1743.0 123
Protein phosphatase 1 regulatory subunit 12A PPP1R12A Tbio Enzyme -3.12546 1290.6 406