Development Level

Tbio 34 | 10,625
Tchem 8 | 1,890
Tdark 5 | 7,003
Tclin 3 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

increased or absent threshold ... 2 | 128
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal placenta size 1 | 10
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
convulsive seizures 1 | 11
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased urine creatinine lev... 1 | 2
decreased vertical activity 1 | 22
edema 1 | 11
hemorrhage 1 | 12
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased CD8-positive, alpha-... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased erythrocyte cell num... 1 | 26
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
prenatal lethality prior to he... 1 | 64
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

osteosarcoma 27 | 7,933
ovarian cancer 24 | 8,491
Carcinoma 23 | 2,147
psoriasis 20 | 6,685
medulloblastoma, large-cell 18 | 6,234
glioblastoma 16 | 5,572
atypical teratoid / rhabdoid tumor 14 | 4,369
lung carcinoma 14 | 2,844
Cancer 12 | 2,346
acute quadriplegic myopathy 12 | 1,157
Breast cancer 11 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
lung cancer 11 | 4,473
malignant mesothelioma 11 | 3,163
pancreatic cancer 11 | 2,300
adult high grade glioma 10 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
invasive ductal carcinoma 10 | 2,950
subependymal giant cell astrocytoma 10 | 2,287
breast carcinoma 9 | 1,614
diabetes mellitus 9 | 1,663
lung adenocarcinoma 9 | 2,714
Hypertrophic Cardiomyopathy 8 | 56
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
non-small cell lung cancer 8 | 2,798
ulcerative colitis 8 | 2,087
Myopathy 7 | 128
juvenile dermatomyositis 7 | 1,189
pediatric high grade glioma 7 | 2,712
primitive neuroectodermal tumor 7 | 3,031
Amyotrophic Lateral Sclerosis 6 | 432
Cardiomyopathy 6 | 110
Dilated cardiomyopathy 6 | 51
Duchenne muscular dystrophy 6 | 602
Hypertension 6 | 293
Primary cutaneous amyloidosis 6 | 26
astrocytic glioma 6 | 2,241
cystic fibrosis 6 | 1,670
ependymoma 6 | 2,514
group 4 medulloblastoma 6 | 1,875
medulloblastoma 6 | 1,524
pilocytic astrocytoma 6 | 3,086
posterior fossa group B ependymoma 6 | 1,530
Becker muscular dystrophy 5 | 187
Cerebrovascular disease 5 | 231
Distal arthrogryposis 5 | 45
Familial isolated dilated cardiomyopathy 5 | 41
Heart disease 5 | 279
Sensorineural hearing loss 5 | 107
atypical teratoid/rhabdoid tumor 5 | 1,095
oligodendroglioma 5 | 2,849
posterior fossa group A ependymoma 5 | 1,511
primary pancreatic ductal adenocarcinoma 5 | 1,271
Cardiomyopathy, Dilated 4 | 47
Cardiomyopathy, Familial Hypertrophic, 1 4 | 6
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 4 | 10
Cardiomyopathy, Hypertrophic, Familial 4 | 21
Kidney disease 4 | 397
Multiple myeloma 4 | 1,327
Ophthalmoplegia 4 | 18
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,170
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
dermatomyositis 4 | 966
group 3 medulloblastoma 4 | 2,254
limb girdle muscular dystrophy 2A 4 | 156
non-small cell lung carcinoma 4 | 413
pancreatic carcinoma 4 | 567
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
spina bifida 4 | 1,064
Amebiasis 3 | 22
Cardiomyopathies 3 | 90
Clostridium difficile colitis 3 | 12
Gastrointestinal stromal tumor 3 | 61
Glaucoma 3 | 135
Impotence 3 | 45
Left ventricular noncompaction 3 | 23
Neoplasm Invasiveness 3 | 127
Neoplasm Metastasis 3 | 138
Nonsyndromic deafness 3 | 121
Pancreatic Neuroendocrine Tumor 3 | 45
Polycystic Ovary Syndrome 3 | 334
Renal Cell Carcinoma 3 | 199
Waldenstrons macroglobulinemia 3 | 764
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
hepatocellular carcinoma 3 | 550
Alzheimer's disease 2 | 644
Atopic dermatitis 2 | 944
Endometriosis 2 | 535
acute myeloid leukemia 2 | 785
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 557
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482

Tissue

Blood and immune system 50 | 17,994
Cardiovascular System 50 | 17,957
Digestive Tract 50 | 18,472
Endocrine System 50 | 18,511
Female tissues 50 | 18,646
Liver and Pancreas 50 | 18,135
Male tissues 50 | 17,968
Nervous System 50 | 18,560
Respiratory system 50 | 17,483
Skin and soft tissues 50 | 18,114
Urinary Tract 50 | 18,443

Target Family

Non-IDG 37 | 11,969
Kinase 7 | 634
Enzyme 5 | 4,146
Transporter 1 | 473

Compartment GO Term

Myosin II complex 50 | 50
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.09889 127.4 77
Titin TTN Tbio Kinase -3.21245 1643.9 116
Death-associated protein kinase 3 DAPK3 Tchem Kinase -1.64328 50.9 237
Supervillin SVIL Tbio Non-IDG -1.26012 20.6 63
Anillin ANLN Tbio Non-IDG -2.22802 168.1 144
WD and tetratricopeptide repeats protein 1 WDTC1 Tbio Non-IDG -4.42045 25187.6 85
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.83237 679.4 189
Myosin-9 MYH9 Tbio Non-IDG -2.98804 996.7 305
Myosin-10 MYH10 Tbio Non-IDG -1.75670 52.1 86
Myosin-1 MYH1 Tbio Non-IDG -1.89804 66.6 99