Development Level

Tbio 7 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal placement of pupils 1 | 6
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
increased bone mineral density 1 | 72
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 12 | 11,493
Cancer 10 | 2,499
Lynch syndrome 10 | 35
Adenoma 9 | 167
Familial adenomatous polyposis 9 | 32
ovarian cancer 9 | 8,520
Sebaceous adenoma 8 | 26
Abdominal Pain 5 | 98
Anxiety 5 | 136
Anxiety disease 5 | 113
Attention deficit hyperactivity disorder 5 | 278
Constipation 5 | 181
Death in early adulthood 5 | 24
Death in early childhood 5 | 82
Death in infancy 5 | 82
Depressive disorder 5 | 409
Dyschezia 5 | 135
Epilepsy 5 | 792
Fatigue 5 | 182
Gastrointestinal Hemorrhage 5 | 52
Hereditary Nonpolyposis Colorectal Cancer 5 | 11
Intermittent migraine headaches 5 | 68
Intracranial hypertension 5 | 32
Irritation - emotion 5 | 68
Malabsorption 5 | 82
Malignant tumor of colon 5 | 19
Migraine Disorders 5 | 76
Muscle Hypertonia 5 | 88
Muscle hypotonia 5 | 571
Nausea and vomiting 5 | 97
Rectal Neoplasms 5 | 18
Seizures 5 | 596
Weight decreased 5 | 103
glioblastoma 5 | 5,792
Abnormality of the abdomen 4 | 14
Autosomal recessive predisposition 4 | 1,442
Axillary freckling 4 | 5
Basal cell carcinoma 4 | 54
Basal cell nevi 4 | 23
Birthmark 4 | 35
Cafe-au-Lait Spots 4 | 37
Colorectal Neoplasms, Hereditary Nonpolyposis 4 | 9
Hematologic Neoplasms 4 | 22
Hereditary Nonpolyposis Colorectal Neoplasms 4 | 8
Hyperpigmented macules 4 | 42
Kidney cancer 4 | 2,613
Leukemia 4 | 104
Lymphoma 4 | 81
Neuroblastoma 4 | 80
Rhabdomyosarcoma 4 | 39
Turcot syndrome 4 | 5
Turcot syndrome (disorder) 4 | 5
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
medulloblastoma 4 | 720
Colorectal cancer 3 | 25
Endometrial carcinoma 3 | 15
Fibrous skin tumor of tuberous sclerosis 3 | 18
Increased gastric cancer 3 | 21
Lynch Syndrome 1 3 | 4
Muir-Torre syndrome 3 | 4
Stomach Neoplasms 3 | 300
Torre-Muir syndrome 3 | 3
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
ovarian neoplasm 3 | 99
psoriasis 3 | 6,694
Adenocarcinoma of duodenum 2 | 2
Adenocarcinoma of lung 2 | 142
Adenocarcinoma of lung (disorder) 2 | 60
Benign digestive system neoplasms 2 | 2
Breast cancer 2 | 3,578
Cafe au lait spots, multiple 2 | 17
Carcinoma of larynx 2 | 2
Colon diverticulum anatomic structure 2 | 15
Colorectal Neoplasms 2 | 243
Diverticular disease of colon 2 | 15
Duodenal Cancer 2 | 2
Endometrial Neoplasms 2 | 55
Endometrial cancer 2 | 311
Hereditary nonpolyposis colorectal carcinoma 2 | 18
Lynch syndrome I (site-specific colonic cancer) 2 | 3
Malignant genitourinary tract tumors 2 | 2
Microsatellite Instability 2 | 12
Neoplasm Metastasis 2 | 168
Ovarian Neoplasms 2 | 102
Prostatic Neoplasms 2 | 495
Sebaceous Adenocarcinoma 2 | 2
Xeroderma pigmentosum group F 2 | 22
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 5 | 12,091
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

MutSbeta complex 12 | 12
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative postmeiotic segregation increased 2-like protein 1 PMS2P1 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 3 PMS2P3 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 11 PMS2P11 Tdark Enzyme -2.19299 339.5 0
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
Structure-specific endonuclease subunit SLX4 SLX4 Tbio Enzyme -1.68794 61.7 56
Protein SLX4IP SLX4IP Tdark Non-IDG 0.44 0.60 18
Protein PMS2CL PMS2CL Tdark Non-IDG -2.19299 339.5 0
DNA mismatch repair protein Mlh1 MLH1 Tbio Non-IDG -3.34283 2352.6 495
DNA mismatch repair protein Msh2 MSH2 Tbio Non-IDG -3.15616 1465.0 503
DNA mismatch repair protein Msh3 MSH3 Tbio Non-IDG -2.44872 276.2 202