Development Level

Tbio 8 | 11,651
Tdark 4 | 6,593

IMPC Phenotype

male infertility 3 | 123
female infertility 2 | 60
abnormal heart morphology 1 | 162
abnormal spleen morphology 1 | 55
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
increased circulating HDL chol... 1 | 80
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
small testis 1 | 58

Disease

Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
Cancer 8 | 2,499
Lynch syndrome 8 | 35
Adenoma 7 | 167
Familial adenomatous polyposis 7 | 32
Sebaceous adenoma 6 | 26
glioblastoma 5 | 5,792
Abdominal Pain 4 | 98
Anxiety 4 | 136
Anxiety disease 4 | 113
Attention deficit hyperactivity disorder 4 | 278
Constipation 4 | 181
Death in early adulthood 4 | 24
Death in early childhood 4 | 82
Death in infancy 4 | 82
Depressive disorder 4 | 409
Dyschezia 4 | 135
Epilepsy 4 | 792
Fatigue 4 | 182
Gastrointestinal Hemorrhage 4 | 52
Hereditary Nonpolyposis Colorectal Cancer 4 | 11
Intermittent migraine headaches 4 | 68
Intracranial hypertension 4 | 32
Irritation - emotion 4 | 68
Malabsorption 4 | 82
Malignant tumor of colon 4 | 19
Migraine Disorders 4 | 76
Muscle Hypertonia 4 | 88
Muscle hypotonia 4 | 571
Nausea and vomiting 4 | 97
Rectal Neoplasms 4 | 18
Seizures 4 | 596
Weight decreased 4 | 103
Colorectal Neoplasms, Hereditary Nonpolyposis 3 | 9
Hereditary Nonpolyposis Colorectal Neoplasms 3 | 8
medulloblastoma 3 | 720
psoriasis 3 | 6,694
Abnormality of the abdomen 2 | 14
Autosomal recessive predisposition 2 | 1,442
Axillary freckling 2 | 5
Basal cell carcinoma 2 | 54
Basal cell nevi 2 | 23
Birthmark 2 | 35
Breast cancer 2 | 3,578
Cafe-au-Lait Spots 2 | 37
Colorectal Neoplasms 2 | 243
Hematologic Neoplasms 2 | 22
Hereditary nonpolyposis colorectal carcinoma 2 | 18
Hyperpigmented macules 2 | 42
Leukemia 2 | 104
Lymphoma 2 | 81
Male infertility 2 | 206
Neoplasm Metastasis 2 | 168
Neuroblastoma 2 | 80
Rhabdomyosarcoma 2 | 39
Turcot syndrome 2 | 5
Turcot syndrome (disorder) 2 | 5
ependymoma 2 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
ovarian neoplasm 2 | 99
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
Acquired metabolic disease 1 | 336
Bloom syndrome 1 | 29
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 7 (disorder) 1 | 1
COPD 1 | 118
Cafe au lait spots, multiple 1 | 17
Carcinoma of colon 1 | 32
Colon diverticulum anatomic structure 1 | 15
Colonic Neoplasms 1 | 142
Colorectal Cancer, Hereditary Nonpolyposis, Type 7 1 | 1
Colorectal cancer 1 | 25
Diverticular disease of colon 1 | 15
Endometrial Neoplasms 1 | 55
Endometrial cancer 1 | 311
Endometrial carcinoma 1 | 15
Esophageal Neoplasms 1 | 69
Fanconi anemia 1 | 56
Fibrous skin tumor of tuberous sclerosis 1 | 18
Increased gastric cancer 1 | 21
Intestinal benign neoplasm 1 | 12
Lynch Syndrome 1 1 | 4
Lynch syndrome I (site-specific colonic cancer) 1 | 3
Neuroectodermal Tumor, Primitive 1 | 8
Neuroectodermal Tumors, Primitive 1 | 8
Ovarian Neoplasms 1 | 102
Pain agnosia 1 | 104
Peutz-Jeghers syndrome 1 | 21
Seckel syndrome 1 | 34
Smooth muscle tumor 1 | 13
Stomach Neoplasms 1 | 300
Uterine fibroid 1 | 28
Xeroderma pigmentosum group F 1 | 22
active Crohn's disease 1 | 922
breast carcinoma 1 | 1,638
progressive supranuclear palsy 1 | 676

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 7 | 4,145
Non-IDG 4 | 12,091
Transcription Factor 1 | 1,400

Compartment GO Term

MutLgamma complex 12 | 12
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA mismatch repair protein Mlh3 MLH3 Tbio Non-IDG -1.78372 64.5 112
DNA mismatch repair protein Mlh1 MLH1 Tbio Non-IDG -3.34283 2352.6 495
E3 ubiquitin-protein ligase CCNB1IP1 CCNB1IP1 Tbio Enzyme -1.11738 15.2 152
Crossover junction endonuclease EME1 EME1 Tbio Enzyme -1.69458 48.2 143
Putative postmeiotic segregation increased 2-like protein 1 PMS2P1 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 3 PMS2P3 Tdark Enzyme -2.19299 339.5 0
Probable E3 SUMO-protein ligase RNF212 RNF212 Tbio Enzyme -0.94925 8.45 87
Putative postmeiotic segregation increased 2-like protein 11 PMS2P11 Tdark Enzyme -2.19299 339.5 0
Cyclin N-terminal domain-containing protein 1 CNTD1 Tbio Non-IDG -0.70615 5.39 69
Protein PMS2CL PMS2CL Tdark Non-IDG -2.19299 339.5 0