Development Level

Tbio 7 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

male infertility 2 | 123
abnormal heart morphology 1 | 162
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
female infertility 1 | 60
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
small testis 1 | 58

Disease

Carcinoma 11 | 11,493
Cancer 9 | 2,499
Lynch syndrome 9 | 35
ovarian cancer 9 | 8,520
Adenoma 8 | 167
Familial adenomatous polyposis 8 | 32
Sebaceous adenoma 7 | 26
Abdominal Pain 5 | 98
Anxiety 5 | 136
Anxiety disease 5 | 113
Attention deficit hyperactivity disorder 5 | 278
Constipation 5 | 181
Death in early adulthood 5 | 24
Death in early childhood 5 | 82
Death in infancy 5 | 82
Depressive disorder 5 | 409
Dyschezia 5 | 135
Epilepsy 5 | 792
Fatigue 5 | 182
Gastrointestinal Hemorrhage 5 | 52
Hereditary Nonpolyposis Colorectal Cancer 5 | 11
Intermittent migraine headaches 5 | 68
Intracranial hypertension 5 | 32
Irritation - emotion 5 | 68
Malabsorption 5 | 82
Malignant tumor of colon 5 | 19
Migraine Disorders 5 | 76
Muscle Hypertonia 5 | 88
Muscle hypotonia 5 | 571
Nausea and vomiting 5 | 97
Rectal Neoplasms 5 | 18
Seizures 5 | 596
Weight decreased 5 | 103
glioblastoma 5 | 5,792
Colorectal Neoplasms, Hereditary Nonpolyposis 4 | 9
Hereditary Nonpolyposis Colorectal Neoplasms 4 | 8
ependymoma 4 | 4,679
Abnormality of the abdomen 3 | 14
Autosomal recessive predisposition 3 | 1,442
Axillary freckling 3 | 5
Basal cell carcinoma 3 | 54
Basal cell nevi 3 | 23
Birthmark 3 | 35
Cafe-au-Lait Spots 3 | 37
Colorectal Neoplasms 3 | 243
Hematologic Neoplasms 3 | 22
Hyperpigmented macules 3 | 42
Kidney cancer 3 | 2,613
Leukemia 3 | 104
Lymphoma 3 | 81
Neuroblastoma 3 | 80
Rhabdomyosarcoma 3 | 39
Turcot syndrome 3 | 5
Turcot syndrome (disorder) 3 | 5
medulloblastoma 3 | 720
ovarian neoplasm 3 | 99
psoriasis 3 | 6,694
Adenocarcinoma of duodenum 2 | 2
Benign digestive system neoplasms 2 | 2
Benign genitourinary tract neoplasm 2 | 2
Cafe au lait spots, multiple 2 | 17
Carcinoma of larynx 2 | 2
Colon diverticulum anatomic structure 2 | 15
Colorectal cancer 2 | 25
Diverticular disease of colon 2 | 15
Duodenal Cancer 2 | 2
Fibrous skin tumor of tuberous sclerosis 2 | 18
Hereditary nonpolyposis colorectal carcinoma 2 | 18
Increased gastric cancer 2 | 21
Lynch Syndrome 1 2 | 4
Lynch syndrome I (site-specific colonic cancer) 2 | 3
Malignant genitourinary tract tumors 2 | 2
Muir-Torre syndrome 2 | 4
Neoplasm Metastasis 2 | 168
Ovarian Neoplasms 2 | 102
Sebaceous Adenocarcinoma 2 | 2
Stomach Neoplasms 2 | 300
Torre-Muir syndrome 2 | 3
breast carcinoma 2 | 1,638
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
Acquired metabolic disease 1 | 336
Carcinoma of colon 1 | 32
Colonic Neoplasms 1 | 142
Endometrial Neoplasms 1 | 55
Endometrial carcinoma 1 | 15
Epicondylitis 1 | 22
Esophageal Neoplasms 1 | 69
Fukuyama congenital muscular dystrophy 1 | 8
Glioma 1 | 74
Glioma Susceptibility 1 1 | 5
Infertility 1 | 188
Intestinal benign neoplasm 1 | 12
Neuroectodermal Tumor, Primitive 1 | 8
Pain agnosia 1 | 104
Peutz-Jeghers syndrome 1 | 21
Pilomatrixoma 1 | 12
Premature ovarian failure 1 | 65
Radiculopathy 1 | 14
Xeroderma pigmentosum 1 | 43

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 5 | 12,091
Transcription Factor 1 | 1,400

Compartment GO Term

MutLbeta complex 11 | 11
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative postmeiotic segregation increased 2-like protein 1 PMS2P1 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 3 PMS2P3 Tdark Enzyme -2.19299 339.5 0
Putative postmeiotic segregation increased 2-like protein 11 PMS2P11 Tdark Enzyme -2.19299 339.5 0
Probable ATP-dependent DNA helicase HFM1 HFM1 Tbio Enzyme -1.67709 47.0 59
Transducin-like enhancer protein 6 TLE6 Tbio Non-IDG -0.85496 7.12 62
Protein PMS2CL PMS2CL Tdark Non-IDG -2.19299 339.5 0
DNA mismatch repair protein Mlh1 MLH1 Tbio Non-IDG -3.34283 2352.6 495
DNA mismatch repair protein Mlh3 MLH3 Tbio Non-IDG -1.78372 64.5 112
DNA mismatch repair protein Msh2 MSH2 Tbio Non-IDG -3.15616 1465.0 503
Mismatch repair endonuclease PMS2 PMS2 Tbio Enzyme -2.19299 339.5 339