Development Level

Tbio 4 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
increased startle reflex 1 | 112

Disease

Carcinoma 4 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
Breast cancer 3 | 3,578
Cardiomyopathy, Dilated 3 | 83
Liver Cirrhosis, Experimental 3 | 769
ovarian cancer 3 | 8,520
Acquired scoliosis 2 | 281
Autosomal recessive predisposition 2 | 1,442
Bell Palsy 2 | 58
Blepharoptosis 2 | 231
Bulbar palsy 2 | 19
Bulbar weakness 2 | 19
Byzanthine arch palate 2 | 194
Cap Myopathy 2 | 2
Centrally nucleated skeletal muscle fibers 2 | 10
Congenital Fiber Type Disproportion 2 | 7
Congenital fiber-type disproportion 2 | 8
Congenital myopathy with fiber type disproportion 2 | 9
Contracture 2 | 96
Contracture of joint 2 | 93
Curvature of spine 2 | 282
Decreased to absent deep tendon reflexes 2 | 42
Deglutition Disorders 2 | 132
Distal arthrogryposis 2 | 42
Esophageal Neoplasms 2 | 69
Esophageal Squamous Cell Carcinoma 2 | 77
Facial Paresis 2 | 59
Facial diplegia 2 | 10
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Failure to gain weight 2 | 365
Feeding difficulties 2 | 127
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Generalized muscle weakness 2 | 57
Highly variable severity 2 | 157
Inflammatory myofibroblastic tumor 2 | 8
Long face 2 | 71
Lumbar lordosis 2 | 35
Motor delay 2 | 147
Muscle hypotonia 2 | 571
Myopathies, Structural, Congenital 2 | 15
Myopathy 2 | 185
Narrow face 2 | 54
Neck muscle weakness 2 | 17
Nemaline Myopathy, Childhood Onset 2 | 6
Nemaline myopathy 2 | 17
Nemaline myopathy 1 2 | 2
Nemaline myopathy 4 2 | 2
Nemaline rods 2 | 7
Neonatal Hypotonia 2 | 64
No development of motor milestones 2 | 147
Pectus excavatum 2 | 100
Pediatric failure to thrive 2 | 365
Prenatal onset 2 | 139
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Recurrent respiratory infections 2 | 141
Reduced fetal movement 2 | 51
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Respiratory insufficiency due to muscle weakness 2 | 37
Squamous cell carcinoma of esophagus 2 | 77
Thin face 2 | 54
Type 1 fibers relatively smaller than type 2 fibers 2 | 5
Variable expressivity 2 | 157
Weak cry 2 | 17
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
tuberculosis and treatment for 6 months 2 | 409
Animal Mammary Neoplasms 1 | 136
Cardiomyopathy 1 | 116
Class III malocclusion 1 | 78
Clubfoot 1 | 39
Congestive heart failure 1 | 113
Downward slant of palpebral fissure 1 | 158
Heart failure 1 | 162
Hemolytic anemia 1 | 77
Hypertrophic Cardiomyopathy 1 | 117
Hypertrophy of lower jaw 1 | 78
Increased size of mandible 1 | 78
Lower limb atrophy 1 | 8
Lower limb muscle hypotrophy 1 | 8
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mandibular hyperplasia 1 | 78
Muscle atrophy, lower limb, distal 1 | 8
Neoplasm Metastasis 1 | 168
Overlapping fingers 1 | 10
Weight Gain 1 | 100
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 4 | 12,091

Compartment GO Term

Muscle thin filament tropomyos... 4 | 4
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
Tropomyosin alpha-1 chain TPM1 Tbio Non-IDG -2.19537 154.3 227
Tropomyosin beta chain TPM2 Tbio Non-IDG -2.36824 225.4 193
Tropomyosin alpha-3 chain TPM3 Tbio Non-IDG -2.29065 184.1 140