Development Level

Tbio 51 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
hypoactivity 3 | 132
abnormal behavior 2 | 298
abnormal kidney morphology 2 | 65
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased circulating triglyce... 2 | 79
decreased prepulse inhibition 2 | 82
increased startle reflex 2 | 112
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating calcium ... 1 | 34
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
protruding tongue 1 | 3
thrombocytosis 1 | 27

Disease

ovarian cancer 38 | 8,520
osteosarcoma 27 | 7,950
Carcinoma 25 | 11,493
glioblastoma 21 | 5,792
medulloblastoma, large-cell 21 | 6,241
psoriasis 21 | 6,694
lung cancer 18 | 4,740
Astrocytoma, Pilocytic 15 | 3,081
Cancer 14 | 2,499
atypical teratoid / rhabdoid tumor 14 | 5,112
Multiple myeloma 13 | 1,332
adult high grade glioma 13 | 3,801
malignant mesothelioma 13 | 3,232
Breast cancer 12 | 3,578
ependymoma 12 | 4,679
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
non-small cell lung cancer 12 | 2,890
tuberculosis 12 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung carcinoma 10 | 2,843
subependymal giant cell astrocytoma 10 | 2,287
Autosomal recessive predisposition 9 | 1,442
Neurodegenerative disease 9 | 414
diabetes mellitus 9 | 1,728
interstitial cystitis 9 | 2,312
pancreatic cancer 9 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Pick disease 8 | 1,894
dermatomyositis 8 | 966
oligodendroglioma 8 | 2,850
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
Failure to gain weight 6 | 365
Pediatric failure to thrive 6 | 365
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
spina bifida 6 | 1,074
Alzheimer's disease 5 | 658
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
interstitial lung disease 5 | 298
ulcerative colitis 5 | 1,819
Bipolar Disorder 4 | 666
Dementia 4 | 175
Endometriosis 4 | 540
Melanoma 4 | 711
Muscle Spasticity 4 | 195
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
gastric cancer 4 | 459
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
Alcoholic Intoxication, Chronic 3 | 289
Allergic hypersensitivity disease 3 | 126
Amyotrophic lateral sclerosis type 3 3 | 17
Breast Neoplasms 3 | 445
Depressive disorder 3 | 409
Dermatitis 3 | 157
Down syndrome 3 | 499
Epilepsy 3 | 792
Fatigue 3 | 182
Hermansky-Pudlak syndrome 3 | 42
Hyperreflexia 3 | 209
Hypertension 3 | 396
Infertility 3 | 188
Liver Cirrhosis, Experimental 3 | 769
Lung disease 3 | 142
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Nerve Degeneration 3 | 121
Pneumonia 3 | 174
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Unipolar Depression 3 | 250
Urticaria 3 | 67
Vascular disease 3 | 319
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
aldosterone-producing adenoma 3 | 665
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
mucosa-associated lymphoid tissue lymphoma 3 | 484
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035

Tissue

Digestive Tract 60 | 17,369
Endocrine System 60 | 18,159
Female tissues 60 | 17,400
Skin and soft tissues 60 | 17,230
Urinary Tract 60 | 16,678
Blood and immune system 59 | 16,909
Male tissues 59 | 17,142
Nervous System 59 | 16,725
Respiratory system 59 | 16,393
Liver and Pancreas 58 | 16,750
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 39 | 12,091
Enzyme 18 | 4,145
Kinase 3 | 634
Epigenetic 1 | 242
Transporter 1 | 473

Compartment GO Term

Multivesicular body 62 | 62
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.67951 5.49 37
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Bone marrow stromal antigen 2 BST2 Tbio Non-IDG -2.59753 424.5 464
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.71624 54.4 193
Charged multivesicular body protein 1b CHMP1B Tbio Non-IDG -0.73722 3.70 71