Development Level

Tbio 41 | 11,445
Tchem 9 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal blood vessel morpholo... 2 | 5
increased circulating sodium l... 2 | 71
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cardiovascular system phenotyp... 1 | 36
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
embryonic growth retardation 1 | 106
hypoactivity 1 | 132
increased body temperature 1 | 9
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 39 | 11,493
ovarian cancer 36 | 8,520
Cancer 32 | 2,499
lung cancer 29 | 4,740
group 3 medulloblastoma 27 | 4,104
osteosarcoma 27 | 7,950
Breast cancer 25 | 3,578
psoriasis 24 | 6,694
malignant mesothelioma 23 | 3,232
medulloblastoma, large-cell 23 | 6,241
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 20 | 5,112
Intellectual disability 18 | 1,016
Nijmegen breakage syndrome 18 | 24
Dull intelligence 17 | 645
Kidney cancer 17 | 2,613
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
ependymoma 17 | 4,679
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
Short stature 15 | 531
primitive neuroectodermal tumor 15 | 3,035
Ataxia telangiectasia 14 | 34
Autosomal recessive predisposition 14 | 1,442
Fanconi anemia 14 | 56
Small head 14 | 374
colon cancer 13 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
non-small cell lung cancer 13 | 2,890
Hereditary Breast and Ovarian Cancer Syndrome 12 | 14
Xeroderma pigmentosum 12 | 43
Chromosome Breakage 11 | 36
Bloom syndrome 10 | 29
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Werner syndrome 10 | 29
adult high grade glioma 10 | 3,801
lung adenocarcinoma 10 | 2,716
Increased chromosomal breakage 9 | 27
astrocytic glioma 9 | 2,597
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
nasopharyngeal carcinoma 9 | 1,058
Liver cancer 8 | 604
Prostatic Neoplasms 8 | 495
Schizophrenia 8 | 1,160
Seckel syndrome 8 | 34
Thrombocytopenia 8 | 197
Waldenstrons macroglobulinemia 8 | 765
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
Astrocytoma, Pilocytic 7 | 3,081
Cryptorchidism 7 | 296
Decreased platelet count 7 | 111
Epilepsy 7 | 792
Hypoplastic mandible condyle 7 | 275
Malignant neoplasm of breast 7 | 15
Mandibular hypoplasia 7 | 275
Microcephaly 7 | 166
Micrognathism 7 | 275
Pancreatic Neoplasm 7 | 85
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
ulcerative colitis 7 | 1,819
Acquired scoliosis 6 | 281
Anemia 6 | 365
Convex nasal ridge 6 | 37
Curvature of spine 6 | 282
Glioma 6 | 74
Hyperactive behavior 6 | 91
Leukopenia 6 | 72
Lymphoma 6 | 81
Lynch syndrome 6 | 35
Pancreatic Neoplasms 6 | 85
Pick disease 6 | 1,894
Prostate cancer 6 | 175
Seizures 6 | 596
pituitary cancer 6 | 1,972
Adenoid Cystic Carcinoma 5 | 99
Carcinoma, Adenoid Cystic 5 | 99
Colorectal Neoplasms 5 | 243
Endometriosis 5 | 540
Fetal Growth Retardation 5 | 189
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Ovarian Neoplasms 5 | 102
Severe combined immunodeficiency 5 | 51
Short palpebral fissure 5 | 38
Upward slant of palpebral fissure 5 | 75
adrenocortical carcinoma 5 | 1,428
hypopigmented skin patch 5 | 59
ovarian neoplasm 5 | 99
subependymal giant cell astrocytoma 5 | 2,287

Tissue

Endocrine System 50 | 18,159
Digestive Tract 49 | 17,369
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Nervous System 49 | 16,725
Skin and soft tissues 49 | 17,230
Urinary Tract 49 | 16,678
Blood and immune system 48 | 16,909
Cardiovascular System 48 | 15,192
Respiratory system 48 | 16,393

Target Family

Non-IDG 33 | 12,091
Enzyme 8 | 4,145
Kinase 5 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

Compartment GO Term

Mre11 complex 50 | 50
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein ARX ARX Tbio Transcription Factor -2.21255 163.7 328
DNA repair and recombination protein RAD54B RAD54B Tbio Non-IDG -1.41173 28.9 153
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
AF4/FMR2 family member 2 AFF2 Tbio Transcription Factor -2.47154 295.5 108
Interleukin-1 receptor accessory protein-like 1 IL1RAPL1 Tbio Non-IDG -1.81770 63.9 132
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
DNA ligase 4 LIG4 Tbio Enzyme -2.14909 140.9 204