Development Level

Tbio 103 | 11,445
Tdark 38 | 6,588
Tchem 10 | 1,598
Tclin 2 | 613

Collection

RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
abnormal behavior 5 | 298
preweaning lethality, complete... 5 | 979
male infertility 4 | 123
hyperactivity 3 | 148
abnormal coat appearance 2 | 31
abnormal embryo size 2 | 220
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased fasted circulating g... 2 | 76
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal embryonic autopod pla... 1 | 2
abnormal facial morphology 1 | 17
abnormal placenta morphology 1 | 5
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal testis morphology 1 | 43
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased heart rate 1 | 18
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
kyphosis 1 | 5
lordosis 1 | 1
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
unresponsive to tactile stimul... 1 | 8
vertebral transformation 1 | 12

Disease

Carcinoma 111 | 11,493
ependymoma 71 | 4,679
osteosarcoma 52 | 7,950
psoriasis 49 | 6,694
ovarian cancer 44 | 8,520
Primary ciliary dyskinesia 39 | 76
nasopharyngeal carcinoma 39 | 1,058
medulloblastoma, large-cell 36 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
chronic rhinosinusitis 35 | 512
glioblastoma 35 | 5,792
Situs Inversus 32 | 65
Breast cancer 30 | 3,578
Kidney cancer 29 | 2,613
group 3 medulloblastoma 29 | 4,104
lung cancer 28 | 4,740
lung adenocarcinoma 25 | 2,716
Kartagener Syndrome 23 | 38
Ciliary Motility Disorders 22 | 38
Male infertility 22 | 206
lung carcinoma 20 | 2,843
Autosomal recessive predisposition 19 | 1,442
adult high grade glioma 19 | 3,801
pituitary cancer 17 | 1,972
Astrocytoma, Pilocytic 16 | 3,081
interstitial cystitis 16 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
malignant mesothelioma 16 | 3,232
primitive neuroectodermal tumor 16 | 3,035
Ciliary Dyskinesia, Primary, 1 15 | 27
Pick disease 14 | 1,894
Polydactyly 14 | 107
invasive ductal carcinoma 14 | 2,951
astrocytic glioma 13 | 2,597
group 4 medulloblastoma 13 | 1,855
non-small cell lung cancer 13 | 2,890
pancreatic cancer 13 | 2,398
Recurrent respiratory infections 12 | 141
cystic fibrosis 12 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
oligodendroglioma 12 | 2,850
tuberculosis 12 | 2,010
Ciliopathy 11 | 71
Infertility 11 | 188
Liver cancer 11 | 604
Schizophrenia 11 | 1,160
Situs ambiguus 11 | 25
Bronchiectasis 10 | 64
Hydrocephalus 10 | 152
cystic fibrosis and chronic rhinosinusitis 10 | 214
ulcerative colitis 10 | 1,819
Hypertensive disease 9 | 292
Retinitis Pigmentosa 9 | 226
Sinusitis 9 | 65
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
Hypogonadism 8 | 173
Nephronophthisis 8 | 80
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
pediatric high grade glioma 8 | 1,064
primary pancreatic ductal adenocarcinoma 8 | 1,109
progressive supranuclear palsy 8 | 676
Alzheimer's disease 7 | 658
Bardet-Biedl syndrome 7 | 51
Congenital hypoplasia of penis 7 | 176
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Obesity 7 | 678
Poor school performance 7 | 645
atypical teratoid/rhabdoid tumor 7 | 357
diabetes mellitus 7 | 1,728
non primary Sjogren syndrome sicca 7 | 891
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
posterior fossa group B ependymoma 7 | 416
subependymal giant cell astrocytoma 7 | 2,287
Cognitive delay 6 | 608
Congenital hypoplasia of ovary 6 | 30
Electroretinogram abnormal 6 | 95
Global developmental delay 6 | 608
Hypoplastic ovary 6 | 30
Increase in blood pressure 6 | 119
Mental and motor retardation 6 | 608
Nystagmus 6 | 317
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
active ulcerative colitis 6 | 764
spina bifida 6 | 1,074
Asthma 5 | 385
Bipolar Disorder 5 | 666
Cancer 5 | 2,499
Endometriosis 5 | 540
Multicystic Dysplastic Kidney 5 | 52
Multiple myeloma 5 | 1,332
Ulnar polydactyly of fingers 5 | 47

Tissue

Endocrine System 151 | 18,159
Female tissues 136 | 17,400
Male tissues 133 | 17,142
Digestive Tract 132 | 17,369
Skin and soft tissues 132 | 17,230
Nervous System 129 | 16,725
Respiratory system 128 | 16,393
Liver and Pancreas 127 | 16,750
Urinary Tract 125 | 16,678
Blood and immune system 121 | 16,909
Cardiovascular System 96 | 15,192

Target Family

Non-IDG 108 | 12,091
Enzyme 16 | 4,145
Transporter 8 | 473
Ion Channel 7 | 344
Transcription Factor 6 | 1,400
GPCR 5 | 408
Kinase 3 | 634

Compartment GO Term

Motile cilium 153 | 153
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.90119 75.2 94
Methyl-CpG-binding domain protein 1 MBD1 Tbio Transcription Factor -2.23809 171.1 297
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Cation channel sperm-associated protein subunit zeta CATSPERZ Tdark Non-IDG 0.15 0.79 0
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
Cilia- and flagella-associated protein 73 CFAP73 Tdark Non-IDG 0.00000 21
T-complex protein 11 homolog TCP11 Tbio Non-IDG -1.26152 18.0 80