Development Level

Tbio 3 | 10,625

IMPC Phenotype

decreased circulating lipase l... 2 | 2
decreased threshold for audito... 2 | 32
preweaning lethality, complete... 2 | 633
abnormal retina morphology 1 | 100
decreased bone mineral content 1 | 157
decreased circulating alkaline... 1 | 41
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating triglyce... 1 | 24
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 57
thrombocytopenia 1 | 46

Disease

Molybdenum cofactor deficiency, complementation group A 2 | 4
Molybdenum cofactor deficiency, complementation group B 2 | 2
Pick disease 2 | 1,893
glioblastoma 2 | 5,572
psoriasis 2 | 6,685
Atopic dermatitis 1 | 944
Breast cancer 1 | 3,098
Cancer 1 | 2,346
Combined molybdoflavoprotein enzyme deficiency 1 | 3
Diabetic Nephropathy 1 | 37
Diffuse large B-cell lymphoma 1 | 42
Disease Progression 1 | 125
Down syndrome 1 | 548
Endometriosis 1 | 535
Hydrolethalus syndrome 1 | 128
Hyperglycemia 1 | 120
Rheumatoid Arthritis 1 | 1,170
active Crohn's disease 1 | 918
astrocytoma 1 | 1,493
atypical teratoid / rhabdoid tumor 1 | 4,369
breast carcinoma 1 | 1,614
chronic lymphosyte leukemia 1 | 232
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,670
diabetes mellitus 1 | 1,663
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 2,514
fibroadenoma 1 | 557
group 3 medulloblastoma 1 | 2,254
group 4 medulloblastoma 1 | 1,875
hereditary spastic paraplegia 1 | 313
invasive ductal carcinoma 1 | 2,950
lung adenocarcinoma 1 | 2,714
lung cancer 1 | 4,473
malignant mesothelioma 1 | 3,163
medulloblastoma, large-cell 1 | 6,234
non-small cell lung cancer 1 | 2,798
oligodendroglioma 1 | 2,849
ovarian cancer 1 | 8,491
pancreatic cancer 1 | 2,300
pancreatic carcinoma 1 | 567
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pediatric high grade glioma 1 | 2,712
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,031
tuberculosis 1 | 1,563
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 3 | 17,994
Digestive Tract 3 | 18,472
Female tissues 3 | 18,646
Liver and Pancreas 3 | 18,135
Male tissues 3 | 17,968
Nervous System 3 | 18,560
Urinary Tract 3 | 18,443
Cardiovascular System 2 | 17,957
Endocrine System 2 | 18,511
Respiratory system 1 | 17,483
Skin and soft tissues 1 | 18,114

Target Family

Enzyme 2 | 4,146
Non-IDG 1 | 11,969

Compartment GO Term

Molybdopterin synthase complex 3 | 3
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thioredoxin-interacting protein TXNIP Tbio Non-IDG -2.41553 322.6 178
Molybdopterin synthase sulfur carrier subunit MOCS2 Tbio Enzyme -2.02533 193.7 72
Molybdopterin synthase catalytic subunit MOCS2 Tbio Enzyme -2.02533 193.7 72