Development Level

Tbio 23 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
cardiovascular system phenotyp... 2 | 36
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
impaired glucose tolerance 2 | 75
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
cataract 1 | 92
convulsive seizures 1 | 13
decreased circulating lactate ... 1 | 3
decreased coping response 1 | 8
decreased exploration in new e... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased grip strength 1 | 41
increased heart rate 1 | 23
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
shortened RR interval 1 | 17
thrombocytopenia 1 | 56

Disease

Carcinoma 24 | 11,493
ovarian cancer 18 | 8,520
medulloblastoma, large-cell 16 | 6,241
osteosarcoma 15 | 7,950
group 3 medulloblastoma 14 | 4,104
glioblastoma 13 | 5,792
Kidney cancer 12 | 2,613
psoriasis 12 | 6,694
Breast cancer 11 | 3,578
ependymoma 11 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung cancer 10 | 4,740
primitive neuroectodermal tumor 10 | 3,035
adrenocortical carcinoma 9 | 1,428
Cancer 8 | 2,499
Intellectual disability 8 | 1,016
atypical teratoid / rhabdoid tumor 8 | 5,112
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
nasopharyngeal carcinoma 6 | 1,058
Atopic dermatitis 5 | 952
Endometriosis 5 | 540
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
juvenile dermatomyositis 5 | 1,187
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
Microcephaly 4 | 166
Pick disease 4 | 1,894
astrocytic glioma 4 | 2,597
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,478
interstitial cystitis 4 | 2,312
pediatric high grade glioma 4 | 1,064
Anteverted nostril 3 | 191
Autosomal recessive predisposition 3 | 1,442
Bardet-Biedl syndrome 3 | 51
Conductive hearing loss 3 | 123
Congenital hypoplasia of penis 3 | 176
Cornelia de Lange syndrome 3 | 21
Delayed bone age 3 | 136
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Leukemia, Myeloid 3 | 18
Low intelligence 3 | 645
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 3 | 16
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephalic osteodysplastic primordial dwarfism type II 3 | 13
Myeloid Leukemia 3 | 19
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Sensorineural Hearing Loss (disorder) 3 | 284
Severe mental retardation (I.Q. 20-34) 3 | 99
Small head 3 | 374
cystic fibrosis and chronic rhinosinusitis 3 | 214
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
tuberculosis 3 | 2,010
Absent auditory canals 2 | 23
Adenoid Cystic Carcinoma 2 | 99
Bilateral fifth finger clinodactyly 2 | 110
Bilateral single transverse palmar creases 2 | 34
Bladder Neoplasm 2 | 112
Byzanthine arch palate 2 | 194
Carcinoma, Adenoid Cystic 2 | 99
Concave bridge of nose 2 | 195
Curvature of little finger 2 | 110
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Failure to gain weight 2 | 365
Gastroesophageal reflux disease 2 | 110
Long philtrum 2 | 137
Micromelia 2 | 58
Muscle Hypertonia 2 | 88
Myopia 2 | 176
Pediatric failure to thrive 2 | 365
Short nose 2 | 132
Small nose 2 | 132
Speech Disorders 2 | 58
Syndactyly of the toes 2 | 45
Thin lips 2 | 49
Urinary Bladder Neoplasms 2 | 114
Waldenstrons macroglobulinemia 2 | 765
medulloblastoma 2 | 720

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Urinary Tract 30 | 16,678
Blood and immune system 29 | 16,909
Cardiovascular System 29 | 15,192
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230

Target Family

Non-IDG 21 | 12,091
Enzyme 5 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400
oGPCR 1 | 421

Compartment GO Term

Mitotic spindle pole 30 | 30
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.47449 292.2 200
CDK5 regulatory subunit-associated protein 2 CDK5RAP2 Tbio Non-IDG -1.70804 54.4 81
WD repeat-containing protein 62 WDR62 Tbio Non-IDG -1.43806 35.5 33
Protein FAM161A FAM161A Tbio Non-IDG -1.10138 14.2 50
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.10209 115.2 244
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.52453 32.7 40