Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal tail morphology 1 | 25
decreased circulating glucose ... 1 | 126
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating glucose ... 1 | 24
prenatal lethality prior to he... 1 | 87
syndactyly 1 | 23

Disease

Carcinoma 10 | 11,493
psoriasis 10 | 6,694
group 3 medulloblastoma 9 | 4,104
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
ovarian cancer 9 | 8,520
primitive neuroectodermal tumor 9 | 3,035
Breast cancer 8 | 3,578
adrenocortical carcinoma 8 | 1,428
glioblastoma 8 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
atypical teratoid / rhabdoid tumor 7 | 5,112
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
lung adenocarcinoma 7 | 2,716
osteosarcoma 7 | 7,950
pancreatic cancer 7 | 2,398
Atopic dermatitis 6 | 952
Endometriosis 6 | 540
adult high grade glioma 6 | 3,801
colon cancer 6 | 1,478
malignant mesothelioma 6 | 3,232
nasopharyngeal carcinoma 6 | 1,058
Cancer 5 | 2,499
Intellectual disability 5 | 1,016
Muscle biopsy shows dystrophic changes 5 | 39
Muscular dystrophy 5 | 75
ependymoma 5 | 4,679
Abnormality of vision 4 | 40
Abnormally small eyeball 4 | 97
Ascites 4 | 22
Cataract 4 | 297
Clouding of corneal stroma 4 | 50
Cognitive delay 4 | 608
Congenital Epicanthus 4 | 177
Corneal Opacity 4 | 53
Dandy-Walker Syndrome 4 | 39
Decreased size of eyeball 4 | 97
Dull intelligence 4 | 645
Glaucoma 4 | 239
Global developmental delay 4 | 608
Hypoplastic mandible condyle 4 | 275
Increased nuchal translucency 4 | 6
Lens Opacities 4 | 231
Low intelligence 4 | 645
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 4 | 5
Mandibular hypoplasia 4 | 275
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Micrognathism 4 | 275
Microphthalmos 4 | 100
Polyhydramnios 4 | 108
Poor school performance 4 | 645
Short stature 4 | 531
Small head 4 | 374
Triangular face 4 | 58
mosaic variegated aneuploidy syndrome 1 4 | 4
Autosomal recessive predisposition 3 | 1,442
Fetal Growth Retardation 3 | 189
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Kidney cancer 3 | 2,613
Phenotypic variability 3 | 150
pediatric high grade glioma 3 | 1,064
Astrocytoma, Pilocytic 2 | 3,081
Carcinoma of colon 2 | 32
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Low Birth Weights 2 | 69
Microcephaly 2 | 166
Mitral valve stenosis 2 | 14
Roberts syndrome 2 | 15
Small for gestational age (disorder) 2 | 69
Stomach Neoplasms 2 | 300
Waldenstrons macroglobulinemia 2 | 765
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
ulcerative colitis 2 | 1,819
Animal Mammary Neoplasms 1 | 136
Atrial Septal Defects 1 | 85
Breast Neoplasms 1 | 445
Cardiac conduction abnormalities 1 | 78
Colorectal Neoplasms 1 | 243
Esophageal Squamous Cell Carcinoma 1 | 77
Hyperhomocysteinemia 1 | 37
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Squamous cell carcinoma of esophagus 1 | 77

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 8 | 12,091
Kinase 3 | 634

Compartment GO Term

Mitotic spindle assembly check... 11 | 11
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 57 kDa CEP57 Tbio Non-IDG -0.98216 11.8 177
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Kinetochore scaffold 1 KNL1 Tbio Non-IDG -2.20924 151.8 85
Dual specificity protein kinase TTK TTK Tchem Kinase -2.33639 219.1 336
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.60409 401.5 393
Mitotic checkpoint serine/threonine-protein kinase BUB1 BUB1 Tchem Kinase -2.31533 200.0 373
Mitotic checkpoint protein BUB3 BUB3 Tbio Non-IDG -1.93368 76.1 256
Centromere/kinetochore protein zw10 homolog ZW10 Tbio Non-IDG -1.64269 41.5 124
Protein zwilch homolog ZWILCH Tbio Non-IDG -1.07121 9.32 112
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta BUB1B Tbio Kinase -2.50682 309.1 479