Development Level

Tbio 10 | 11,445

IMPC Phenotype

decreased bone mineral content 2 | 151
male infertility 2 | 123
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
shortened RR interval 1 | 17

Disease

Carcinoma 10 | 11,493
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 7 | 6,241
Kidney cancer 6 | 2,613
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
ovarian cancer 6 | 8,520
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Rheumatoid arthritis 5 | 1,191
ependymoma 5 | 4,679
osteosarcoma 5 | 7,950
Breast cancer 4 | 3,578
Cornelia de Lange syndrome 4 | 21
Leukemia, Myeloid 4 | 18
Myeloid Leukemia 4 | 19
adult high grade glioma 4 | 3,801
malignant mesothelioma 4 | 3,232
Abnormally low-pitched voice 3 | 6
Absent auditory canals 3 | 23
Absent external auditory canals 3 | 23
Anteverted nostril 3 | 191
Anxiety 3 | 136
Anxiety disease 3 | 113
Atresia of the external auditory canal 3 | 23
Atretic auditory canal 3 | 23
Attention deficit hyperactivity disorder 3 | 278
Bilateral fifth finger clinodactyly 3 | 110
Bilateral single transverse palmar creases 3 | 34
Bladder Neoplasm 3 | 112
Blepharitis 3 | 23
Blepharoptosis 3 | 231
Bowed and upward slanting eyebrows 3 | 41
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Bushy eyebrows 3 | 49
Byzanthine arch palate 3 | 194
Cancer 3 | 2,499
Cellulitis of eyelid 3 | 17
Cognitive delay 3 | 608
Concave bridge of nose 3 | 195
Conductive hearing loss 3 | 123
Corneal diameter decreased 3 | 47
Curvature of little finger 3 | 110
Cutis marmorata 3 | 32
Delayed bone age 3 | 136
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Downturned corners of mouth 3 | 48
Failure to gain weight 3 | 365
Feeding difficulties in infancy 3 | 175
Gastroesophageal reflux disease 3 | 110
Generalized hirsutism 3 | 36
Global developmental delay 3 | 608
Heartburn 3 | 78
Hypoplasia of nipple 3 | 16
Hypoplastic feet 3 | 66
Hypoplastic mandible condyle 3 | 275
Intrauterine retardation 3 | 176
Joint stiffness 3 | 84
Late tooth eruption 3 | 61
Long eyelashes 3 | 37
Long philtrum 3 | 137
Low anterior hairline 3 | 30
Low posterior hairline 3 | 52
Low-set, posteriorly rotated ears 3 | 110
Mental and motor retardation 3 | 608
Micromelia 3 | 58
Multicystic Dysplastic Kidney 3 | 52
Muscle Hypertonia 3 | 88
Myopia 3 | 176
Obsessive compulsive behavior 3 | 25
Pediatric failure to thrive 3 | 365
Penile hypospadias 3 | 106
Premature Birth 3 | 77
Premature birth of newborn 3 | 67
Proximally placed thumbs 3 | 17
Radioulnar synostosis 3 | 35
Sensorineural Hearing Loss (disorder) 3 | 284
Severe mental retardation (I.Q. 20-34) 3 | 99
Severe postnatal growth retardation 3 | 16
Short nose 3 | 132
Sleep disturbances 3 | 37
Small hand 3 | 36
Small labia majora 3 | 16
Small nose 3 | 132
Speech Disorders 3 | 58
Syndactyly of the toes 3 | 45
Synophrys 3 | 40
Thick, flared eyebrows 3 | 41
Thin lips 3 | 49
Urinary Bladder Neoplasms 3 | 114
Vesico-Ureteral Reflux 3 | 33
Waldenstrons macroglobulinemia 3 | 765
Wide skull shape 3 | 88
Widely spaced teeth 3 | 31
astrocytic glioma 3 | 2,597
lung adenocarcinoma 3 | 2,716
obsessive-compulsive disorder 3 | 61
oligodendroglioma 3 | 2,850

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 10 | 12,091

Compartment GO Term

Mitotic cohesin complex 10 | 10
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
Structural maintenance of chromosomes protein 1B SMC1B Tbio Non-IDG -1.33220 21.7 87
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.10209 115.2 244
Shugoshin 1 SGO1 Tbio Non-IDG -2.44224 279.8 148
Structural maintenance of chromosomes protein 1A SMC1A Tbio Non-IDG -1.84148 64.7 686
Shugoshin 2 SGO2 Tbio Non-IDG -1.31971 22.3 90
Sister chromatid cohesion protein PDS5 homolog A PDS5A Tbio Non-IDG -1.71103 53.7 172
Cohesin subunit SA-2 STAG2 Tbio Non-IDG -2.11039 130.4 227
Double-strand-break repair protein rad21 homolog RAD21 Tbio Non-IDG -2.27227 173.4 208
Meiotic recombination protein REC8 homolog REC8 Tbio Non-IDG -0.39877 2.78 163