Development Level

Tdark 20 | 6,588
Tbio 11 | 11,445

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased circulating creatini... 1 | 38
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 18 | 8,520
lung cancer 13 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
osteosarcoma 12 | 7,950
Multiple myeloma 7 | 1,332
Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
glioblastoma 5 | 5,792
non primary Sjogren syndrome sicca 5 | 891
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
Disease Progression 3 | 136
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
Brain glioma 2 | 7
Breast cancer 2 | 3,578
Pseudoxanthoma elasticum 2 | 18
diabetes mellitus 2 | 1,728
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
Acidosis, Lactic 1 | 97
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Anemia 1 | 365
Autosomal recessive predisposition 1 | 1,442
Avian influenza 1 | 7
Brachydactyly 1 | 156
Campylobacteriosis 1 | 11
Cancer 1 | 2,499
Cockayne syndrome 1 | 60
Combined Oxidative Phosphorylation Deficiency 2 1 | 1
Combined oxidative phosphorylation defect type 2 1 | 2
Combined oxidative phosphorylation deficiency 1 | 14
Congenital anomaly of face 1 | 56
Coronary artery disease 1 | 268
Crohn's disease 1 | 321
Dilated ventricles (finding) 1 | 121
Disease Models, Animal 1 | 155
Distortion of face 1 | 46
Dysmorphic facies 1 | 46
Edema 1 | 81
Elevated hepatic transaminases 1 | 81
Epilepsy 1 | 792
Eumycotic mycetoma 1 | 3
Functional diarrhea 1 | 4
Funny looking face 1 | 46
Fusariosis 1 | 6
Hepatic enzyme increased 1 | 81
Hypokinesia 1 | 19
Increased serum lactate 1 | 60
Kidney cancer 1 | 2,613
Lactic acidemia 1 | 95
Lateral medullary syndrome 1 | 4
Leigh disease 1 | 100
Lethargy 1 | 77
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low Birth Weights 1 | 69
Megaloblastic anemia 1 | 18
Metabolic acidosis 1 | 90
Mitochondrial encephalomyopathy 1 | 15
Neonatal Hypotonia 1 | 64
Nonsyndromic deafness 1 | 142
Prenatal onset 1 | 139
Redundant neck skin 1 | 4
Rubeosis iridis 1 | 4
Small for gestational age (disorder) 1 | 69
Subclinical abnormal liver function tests 1 | 81
Subcutaneous mycosis 1 | 2
Tinea pedis 1 | 29
Transaminases increased 1 | 81
Waldenstrons macroglobulinemia 1 | 765
active ulcerative colitis 1 | 764
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
facial deformity 1 | 46
gastric cancer 1 | 459
glioblastoma multiforme 1 | 142
interstitial lung disease 1 | 298
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678

Target Family

Non-IDG 30 | 12,091
Enzyme 1 | 4,145

Compartment GO Term

Mitochondrial small ribosomal ... 31 | 31
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
28S ribosomal protein S16, mitochondrial MRPS16 Tbio Non-IDG -0.33244 1.70 61
28S ribosomal protein S28, mitochondrial MRPS28 Tdark Non-IDG 0.00000 1.00 56
28S ribosomal protein S26, mitochondrial MRPS26 Tdark Non-IDG -0.22018 1.24 61
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.92202 82.6 72
28S ribosomal protein S35, mitochondrial MRPS35 Tdark Non-IDG 0.00000 84
28S ribosomal protein S21, mitochondrial MRPS21 Tdark Non-IDG 0.60 0.25 0
28S ribosomal protein S10, mitochondrial MRPS10 Tdark Non-IDG -0.42752 2.60 107
28S ribosomal protein S6, mitochondrial MRPS6 Tdark Non-IDG 0.02 1.21 37
Translation initiation factor IF-3, mitochondrial MTIF3 Tbio Non-IDG -1.07965 13.0 181