Development Level

Tdark 56 | 6,588
Tbio 39 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
abnormal bone structure 2 | 187
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
decreased circulating glucose ... 1 | 126
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 61 | 8,520
osteosarcoma 36 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
lung cancer 27 | 4,740
Carcinoma 22 | 11,493
Multiple myeloma 17 | 1,332
psoriasis 17 | 6,694
non primary Sjogren syndrome sicca 15 | 891
Breast cancer 12 | 3,578
group 3 medulloblastoma 12 | 4,104
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
non-small cell lung cancer 11 | 2,890
acute myeloid leukemia 8 | 783
atypical teratoid / rhabdoid tumor 8 | 5,112
malignant mesothelioma 8 | 3,232
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
colon cancer 5 | 1,478
ependymoma 5 | 4,679
lung adenocarcinoma 5 | 2,716
pediatric high grade glioma 5 | 1,064
Brain glioma 4 | 7
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
invasive ductal carcinoma 4 | 2,951
Combined oxidative phosphorylation deficiency 3 | 14
Disease Progression 3 | 136
Leigh disease 3 | 100
Ophthalmoplegia 3 | 106
Optic Atrophy 3 | 242
Pick disease 3 | 1,894
Retinitis pigmentosa 4 3 | 38
Stomach Neoplasms 3 | 300
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 409
Acidosis, Lactic 2 | 97
Acquired metabolic disease 2 | 336
Adenocarcinoma of lung 2 | 142
Autosomal recessive predisposition 2 | 1,442
Disease Models, Animal 2 | 155
Elevated hepatic transaminases 2 | 81
Hepatic enzyme increased 2 | 81
Increased serum lactate 2 | 60
Lactic acidemia 2 | 95
Leber hereditary optic neuropathy 2 | 14
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Obesity 2 | 678
Pseudoxanthoma elasticum 2 | 18
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
primitive neuroectodermal tumor 2 | 3,035
Abnormal vision 1 | 52
Age related macular degeneration 1 | 72
Alcohol dependence 1 | 107
Amyotrophic lateral sclerosis type 5 1 | 13
Carcinoma, Squamous Cell 1 | 110
Cervical cancer 1 | 24
Charcot-Marie-Tooth disease 1 | 62
DiGeorge syndrome 1 | 47
Dyslexia 1 | 43
Dyspnea 1 | 76
Eastern equine encephalitis 1 | 16
Edema 1 | 81
Enamel caries 1 | 8
Esophageal atresia 1 | 43
Gastroenteritis 1 | 41
Gastroparesis 1 | 22
Gilles de la Tourette syndrome 1 | 47
Hemianopsia 1 | 15
Hemiparesis 1 | 34
Hereditary spherocytosis type 1 1 | 23
Hypercalcemia 1 | 59
Intermittent migraine headaches 1 | 68
Migraine Disorders 1 | 76
Neuronal ceroid lipofuscinosis 1 1 | 15
Peripheral Neuropathy 1 | 134
Pneumocystosis 1 | 17
Polyneuropathy 1 | 64
Specific language impairment 1 | 34
Static Tremor 1 | 21
Tonic - clonic seizures 1 | 44
Velocardiofacial syndrome 1 | 46

Tissue

Blood and immune system 94 | 16,909
Cardiovascular System 94 | 15,192
Digestive Tract 94 | 17,369
Endocrine System 94 | 18,159
Female tissues 94 | 17,400
Liver and Pancreas 94 | 16,750
Male tissues 94 | 17,142
Nervous System 94 | 16,725
Respiratory system 94 | 16,393
Skin and soft tissues 94 | 17,230
Urinary Tract 94 | 16,678

Target Family

Non-IDG 84 | 12,091
Enzyme 12 | 4,145

Compartment GO Term

Mitochondrial ribosome 96 | 96
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial ribosome-associated GTPase 1 MTG1 Tdark Enzyme -0.54103 1.89 89
39S ribosomal protein L22, mitochondrial MRPL22 Tdark Non-IDG 0.70 0.21 64
28S ribosomal protein S28, mitochondrial MRPS28 Tdark Non-IDG 0.00000 1.00 56
Uncharacterized protein C2orf15 C2orf15 Tdark Non-IDG 1.32 0.05 16
39S ribosomal protein L45, mitochondrial MRPL45 Tdark Non-IDG 0.51 0.23 0
39S ribosomal protein L49, mitochondrial MRPL49 Tbio Non-IDG -2.76367 555.1 76
39S ribosomal protein L11, mitochondrial MRPL11 Tdark Non-IDG -0.63555 3.41 198
39S ribosomal protein L20, mitochondrial MRPL20 Tdark Non-IDG 1.23 0.05 48
39S ribosomal protein L32, mitochondrial MRPL32 Tdark Non-IDG 0.18 0.93 52
39S ribosomal protein L9, mitochondrial MRPL9 Tdark Non-IDG 1.00 0.05 133