Development Level

Tclin 47 | 613
Tbio 44 | 11,445
Tdark 6 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 23 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 7 | 278
abnormal embryo size 6 | 220
embryonic growth retardation 4 | 106
pallor 4 | 34
cataract 3 | 92
abnormal behavior 2 | 298
abnormal embryo turning 2 | 31
abnormal lens morphology 2 | 81
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
decreased bone mineral content 2 | 151
decreased vertical activity 2 | 208
increased circulating sodium l... 2 | 71
prenatal lethality prior to he... 2 | 87
abnormal allantois morphology 1 | 8
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryonic autopod pla... 1 | 2
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube morpholog... 1 | 12
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 5
abnormal sensory capabilities-... 1 | 8
abnormal tail bud morphology 1 | 8
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
abnormal vitreous body morphol... 1 | 10
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased total retina thickne... 1 | 17
enlarged heart atrium 1 | 4
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale liver 1 | 6
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
vertebral fusion 1 | 23

Disease

ovarian cancer 57 | 8,520
Diabetes mellitus type 2 46 | 69
Treatment Refractory Type 2 Diabetes Mellitus 46 | 53
Cerebellar Ataxia 37 | 304
Multiple myeloma 37 | 1,332
Autosomal recessive predisposition 35 | 1,442
Leigh disease 34 | 100
osteosarcoma 33 | 7,950
Mitochondrial complex I deficiency 30 | 46
Acidosis, Lactic 28 | 97
Lactic acidemia 28 | 95
Sensorineural Hearing Loss (disorder) 27 | 284
Blepharoptosis 26 | 231
Carcinoma 26 | 11,493
Nystagmus 25 | 317
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Cognitive delay 24 | 608
Epilepsy 24 | 792
Global developmental delay 24 | 608
Mental and motor retardation 24 | 608
Seizures 24 | 596
Highly variable clinical phenotype 23 | 150
Highly variable phenotype and severity 23 | 150
Highly variable phenotype, even within families 23 | 150
Phenotypic variability 23 | 150
Failure to gain weight 22 | 365
Hyperreflexia 22 | 209
Increased serum lactate 22 | 60
Muscle Weakness 22 | 170
Muscle hypotonia 22 | 571
Pediatric failure to thrive 22 | 365
psoriasis 22 | 6,694
Dystonia 21 | 164
Mitochondrial Complex 1 Deficiency 21 | 28
Muscle Spasticity 21 | 195
Optic Atrophy 21 | 242
Strabismus 21 | 270
CSF lactate increased 20 | 33
Dystonic disease 20 | 106
Respiratory Failure 20 | 104
lung cancer 20 | 4,740
Developmental regression 19 | 95
Loss of developmental milestones 19 | 95
Mental deterioration in childhood 19 | 95
Neurodevelopmental regression 19 | 95
Psychomotor regression 19 | 95
Psychomotor regression beginning in infancy 19 | 95
Psychomotor regression in infants 19 | 95
Psychomotor regression, progressive 19 | 95
Abnormal mitochondria in muscle tissue 18 | 20
Hypertrophic Cardiomyopathy 18 | 117
Leigh syndrome 18 | 28
NADH:Q(1) Oxidoreductase deficiency 18 | 24
Ophthalmoplegia 17 | 106
astrocytic glioma 17 | 2,597
medulloblastoma, large-cell 17 | 6,241
Dull intelligence 16 | 645
Hypoglycemia 16 | 152
Intellectual disability 16 | 1,016
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
ependymoma 16 | 4,679
glioblastoma 16 | 5,792
Atrophy of cerebellum 15 | 103
Babinski Reflex 15 | 100
Cerebellar degeneration 15 | 103
Impaired exercise tolerance 15 | 42
Infratentorial atrophy 15 | 103
Dysarthria 14 | 192
Retinitis Pigmentosa 14 | 226
atypical teratoid / rhabdoid tumor 14 | 5,112
diabetes mellitus 14 | 1,728
Decreased tendon reflex 13 | 122
Feeding difficulties in infancy 13 | 175
Infantile onset 13 | 238
Liver Failure 13 | 73
Neurogenic Muscular Atrophy 13 | 139
Neurogenic muscle atrophy, especially in the lower limbs 13 | 139
Skeletal muscle atrophy 13 | 139
X-linked dominant 13 | 57
muscle degeneration 13 | 139
Acute necrotizing encephalopathy 12 | 14
Blind Vision 12 | 111
Blindness, Legal 12 | 110
Brain Edema 12 | 50
Cerebral Edema 12 | 30
Comatose 12 | 56
Growth delay 12 | 114
Growth failure 12 | 114
Growth retardation 12 | 115
Lethargy 12 | 77
Leukodystrophy 12 | 55
Pallor of optic disc 12 | 39
Poor growth 12 | 114
Progressive macrocephaly 12 | 18
Very poor growth 12 | 114
Vomiting 12 | 116
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291

Tissue

Blood and immune system 98 | 16,909
Cardiovascular System 98 | 15,192
Digestive Tract 98 | 17,369
Endocrine System 98 | 18,159
Female tissues 98 | 17,400
Liver and Pancreas 98 | 16,750
Male tissues 98 | 17,142
Nervous System 98 | 16,725
Skin and soft tissues 98 | 17,230
Urinary Tract 98 | 16,678
Respiratory system 96 | 16,393

Target Family

Enzyme 75 | 4,145
Non-IDG 22 | 12,091
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Mitochondrial respiratory chai... 99 | 99
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..