Development Level

Tbio 7 | 10,625
Tchem 2 | 1,890

Disease

osteosarcoma 6 | 7,933
ovarian cancer 6 | 8,484
Pyruvate decarboxylase deficiency 4 | 15
medulloblastoma, large-cell 4 | 6,234
Lactic acidosis 3 | 42
Leigh disease 3 | 81
Multiple myeloma 3 | 1,327
Carcinoma 2 | 2,147
Myocardial Ischemia 2 | 169
Pick disease 2 | 1,893
Pyruvate Dehydrogenase Complex Deficiency Disease 2 | 2
acute quadriplegic myopathy 2 | 1,157
atypical teratoid / rhabdoid tumor 2 | 4,369
ductal carcinoma in situ 2 | 1,745
glioblastoma 2 | 5,572
hereditary spastic paraplegia 2 | 313
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung adenocarcinoma 2 | 2,713
lung cancer 2 | 4,466
lung carcinoma 2 | 2,844
oligodendroglioma 2 | 2,849
subependymal giant cell astrocytoma 2 | 2,287
Acidosis, Lactic 1 | 4
Anismus 1 | 2
Blastic phase chronic myeloid leukemia 1 | 58
Cardia cancer 1 | 3
Cardiomyopathies 1 | 90
Chancroid 1 | 8
Cholangitis 1 | 20
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Coffin-Lowry syndrome 1 | 10
Degenerative polyarthritis 1 | 93
Disease Progression 1 | 125
Dysembryoplastic neuroepithelial tumor 1 | 10
Dystonia 1 | 77
Goldenhar syndrome 1 | 19
Hypersensitivity reaction type II disease 1 | 235
IGA Glomerulonephritis 1 | 454
Intellectual disability 1 | 573
Liver Cirrhosis 1 | 101
Periventricular leukomalacia 1 | 6
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Primary biliary cirrhosis 1 | 43
Prostatic Neoplasms 1 | 471
Pyruvate Dehydrogenase E1 Alpha Deficiency 1 | 1
Pyruvate Dehydrogenase E1-Beta Deficiency 1 | 1
Pyruvate Dehydrogenase E2 Deficiency 1 | 1
Pyruvate Dehydrogenase E3-Binding Protein Deficiency 1 | 1
Pyruvate Metabolism, Inborn Errors 1 | 1
Renal Cell Carcinoma 1 | 199
Retinoschisis 1 | 8
Stomach Neoplasms 1 | 282
Subcorneal pustular dermatosis 1 | 2
Ulnar neuropathy 1 | 7
active Crohn's disease 1 | 918
adult high grade glioma 1 | 2,148
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
dermatomyositis 1 | 933
ependymoma 1 | 2,514
group 4 medulloblastoma 1 | 1,875
inflammatory breast cancer 1 | 404
invasive ductal carcinoma 1 | 2,950
juvenile dermatomyositis 1 | 1,189
malignant mesothelioma 1 | 3,162
non-small cell lung cancer 1 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pilocytic astrocytoma 1 | 3,086
psoriasis 1 | 6,685
sonic hedgehog group medulloblastoma 1 | 1,482
systemic lupus erythematosus 1 | 156
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 9 | 17,995
Cardiovascular System 9 | 17,958
Digestive Tract 9 | 18,473
Endocrine System 9 | 18,512
Female tissues 9 | 18,647
Liver and Pancreas 9 | 18,136
Male tissues 9 | 17,969
Nervous System 9 | 18,561
Respiratory system 9 | 17,484
Skin and soft tissues 9 | 18,115
Urinary Tract 9 | 18,444

Target Family

Enzyme 5 | 4,146
Transcription Factor 2 | 1,400
Kinase 1 | 634
Non-IDG 1 | 11,971

Compartment GO Term

Mitochondrial pyruvate dehydro... 9 | 9
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

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