Development Level

Tbio 680 | 11,445
Tdark 160 | 6,588
Tchem 109 | 1,598
Tclin 87 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 115 | 979
embryonic lethality prior to o... 33 | 239
embryonic lethality prior to t... 31 | 278
abnormal behavior 18 | 298
preweaning lethality, incomple... 18 | 499
abnormal embryo size 14 | 220
decreased total body fat amoun... 14 | 207
decreased vertical activity 12 | 208
embryonic growth retardation 12 | 106
increased lean body mass 12 | 172
increased total body fat amoun... 12 | 134
decreased body weight 11 | 161
decreased bone mineral content 11 | 151
hyperactivity 11 | 148
cataract 10 | 92
decreased lean body mass 9 | 135
enlarged heart 9 | 210
increased mean corpuscular hem... 9 | 96
prenatal lethality prior to he... 9 | 87
abnormal bone structure 8 | 187
abnormal lens morphology 8 | 81
decreased circulating glucose ... 8 | 126
hypoactivity 7 | 132
abnormal heart morphology 6 | 162
decreased bone mineral density 6 | 126
decreased circulating LDL chol... 6 | 38
decreased circulating alkaline... 6 | 46
decreased circulating total pr... 6 | 49
decreased grip strength 6 | 116
decreased mean corpuscular vol... 6 | 79
increased circulating alkaline... 6 | 122
increased circulating choleste... 6 | 66
increased startle reflex 6 | 112
pallor 6 | 34
abnormal seminal vesicle morph... 5 | 114
abnormal sleep behavior 5 | 70
decreased body length 5 | 101
decreased circulating HDL chol... 5 | 68
decreased circulating choleste... 5 | 93
decreased fasted circulating g... 5 | 65
increased circulating HDL chol... 5 | 80
increased circulating phosphat... 5 | 26
increased circulating sodium l... 5 | 71
increased fasted circulating g... 5 | 76
increased heart weight 5 | 62
persistence of hyaloid vascula... 5 | 33
small testis 5 | 58
thrombocytopenia 5 | 56
abnormal coat-hair pigmentatio... 4 | 64
abnormal cranium morphology 4 | 36
abnormal gait 4 | 69
abnormal neural tube closure 4 | 46
abnormal skin morphology 4 | 50
abnormal testis morphology 4 | 43
decreased circulating creatini... 4 | 39
decreased circulating phosphat... 4 | 27
decreased circulating serum al... 4 | 82
decreased mean platelet volume 4 | 25
decreased red blood cell distr... 4 | 41
decreased startle reflex 4 | 75
decreased total retina thickne... 4 | 17
increased circulating bilirubi... 4 | 16
male infertility 4 | 123
small superior vagus ganglion 4 | 74
abnormal embryo turning 3 | 31
abnormal epididymis morphology 3 | 42
abnormal retina morphology 3 | 71
abnormal tooth morphology 3 | 24
decreased circulating aspartat... 3 | 34
decreased circulating chloride... 3 | 30
decreased circulating insulin ... 3 | 76
decreased erythrocyte cell num... 3 | 62
decreased heart weight 3 | 27
decreased hematocrit 3 | 46
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
decreased prepulse inhibition 3 | 82
enlarged epididymis 3 | 31
impaired righting response 3 | 26
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased circulating calcium ... 3 | 34
increased circulating serum al... 3 | 22
increased circulating total pr... 3 | 28
increased hemoglobin content 3 | 45
increased mean corpuscular vol... 3 | 92
increased prepulse inhibition 3 | 32
increased red blood cell distr... 3 | 34
pale yolk sac 3 | 25
short tibia 3 | 97
abnormal heart left ventricle ... 2 | 16
abnormal lung morphology 2 | 26
abnormal skin coloration 2 | 25
abnormal vertebrae morphology 2 | 18
decreased circulating calcium ... 2 | 36
decreased circulating iron lev... 2 | 32
decreased circulating potassiu... 2 | 20
impaired glucose tolerance 2 | 75
increased monocyte cell number 2 | 63

Disease

ovarian cancer 562 | 8,520
Carcinoma 479 | 11,493
osteosarcoma 438 | 7,950
lung cancer 322 | 4,740
psoriasis 318 | 6,694
medulloblastoma, large-cell 310 | 6,241
glioblastoma 266 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 236 | 1,962
atypical teratoid / rhabdoid tumor 234 | 5,112
ependymoma 208 | 4,679
Autosomal recessive predisposition 193 | 1,442
group 3 medulloblastoma 179 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 175 | 3,291
Multiple myeloma 172 | 1,332
adult high grade glioma 168 | 3,801
Breast cancer 167 | 3,578
malignant mesothelioma 155 | 3,232
Cancer 151 | 2,499
non-small cell lung cancer 148 | 2,890
astrocytic glioma 144 | 2,597
invasive ductal carcinoma 140 | 2,951
lung adenocarcinoma 130 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 124 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 123 | 2,989
oligodendroglioma 122 | 2,850
diabetes mellitus 121 | 1,728
Epilepsy 116 | 792
primitive neuroectodermal tumor 116 | 3,035
Muscle hypotonia 113 | 571
Cognitive delay 107 | 608
Global developmental delay 107 | 608
Mental and motor retardation 107 | 608
lung carcinoma 106 | 2,843
Astrocytoma, Pilocytic 105 | 3,081
tuberculosis 104 | 2,010
ulcerative colitis 103 | 1,819
Pick disease 101 | 1,894
Seizures 101 | 596
pancreatic cancer 100 | 2,398
group 4 medulloblastoma 95 | 1,855
breast carcinoma 89 | 1,638
Schizophrenia 88 | 1,160
subependymal giant cell astrocytoma 87 | 2,287
Leigh disease 86 | 100
Cerebellar Ataxia 85 | 304
Intellectual disability 85 | 1,016
interstitial cystitis 84 | 2,312
Acidosis, Lactic 81 | 97
non primary Sjogren syndrome sicca 81 | 891
Lactic acidemia 80 | 95
Obesity 80 | 678
ductal carcinoma in situ 79 | 1,745
Waldenstrons macroglobulinemia 74 | 765
Dull intelligence 73 | 645
Low intelligence 73 | 645
Mental Retardation 73 | 645
Mental deficiency 73 | 645
Poor school performance 73 | 645
Failure to gain weight 72 | 365
Neurodegenerative disease 72 | 414
Pediatric failure to thrive 72 | 365
acute myeloid leukemia 69 | 783
colon cancer 69 | 1,478
Alzheimer's disease 68 | 658
adrenocortical carcinoma 68 | 1,428
cystic fibrosis 68 | 1,696
pituitary cancer 67 | 1,972
Optic Atrophy 65 | 242
Hypoglycemia 61 | 152
Liver Cirrhosis, Experimental 61 | 769
Dystonia 60 | 164
astrocytoma 58 | 1,146
Blepharoptosis 56 | 231
Kidney cancer 56 | 2,613
Rheumatoid arthritis 56 | 1,191
Neuropathy 54 | 261
Parkinson's disease 54 | 392
acute quadriplegic myopathy 54 | 1,158
dermatomyositis 54 | 966
Nystagmus 53 | 317
Diabetes mellitus type 2 52 | 69
Sensorineural Hearing Loss (disorder) 52 | 284
Treatment Refractory Type 2 Diabetes Mellitus 51 | 53
aldosterone-producing adenoma 51 | 665
Anemia 50 | 365
Increased serum lactate 50 | 60
Toxic encephalopathy 50 | 141
Hyperreflexia 49 | 209
Infantile onset 49 | 238
Vomiting 48 | 116
Bipolar Disorder 47 | 666
Breast Neoplasms 47 | 445
Mammary Neoplasms 47 | 425
pediatric high grade glioma 47 | 1,064
Dystonic disease 46 | 106
Muscle Weakness 46 | 170
Hypertrophic Cardiomyopathy 45 | 117
Stomach Neoplasms 45 | 300
Phenotypic variability 44 | 150
juvenile dermatomyositis 44 | 1,187

Tissue

Endocrine System 1,023 | 18,159
Digestive Tract 1,015 | 17,369
Skin and soft tissues 1,010 | 17,230
Female tissues 1,009 | 17,400
Blood and immune system 1,006 | 16,909
Liver and Pancreas 1,006 | 16,750
Male tissues 1,006 | 17,142
Urinary Tract 1,005 | 16,678
Nervous System 1,004 | 16,725
Respiratory system 990 | 16,393
Cardiovascular System 984 | 15,192

Target Family

Enzyme 514 | 4,145
Non-IDG 394 | 12,091
Transporter 65 | 473
Kinase 41 | 634
Transcription Factor 8 | 1,400
Epigenetic 6 | 242
GPCR 3 | 408
Nuclear Receptor 3 | 48
Ion Channel 2 | 344

Compartment GO Term

Mitochondrial part 1,036 | 1,036
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
DnaJ homolog subfamily C member 15 DNAJC15 Tbio Non-IDG -1.67016 50.2 31
MICOS complex subunit MIC13 C19orf70 Tbio Non-IDG -1.22343 17.5 18
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Solute carrier family 25 member 47 SLC25A47 Tbio Transporter 0.03 0.48 83
BRI3-binding protein BRI3BP Tbio Non-IDG -0.63682 5.24 115
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial MCCC1 Tbio Enzyme -1.91194 82.4 102
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 Tclin Enzyme -0.62794 3.79 65