Development Level

Tbio 77 | 11,445
Tclin 15 | 613
Tchem 9 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 16 | 979
embryonic lethality prior to t... 5 | 278
abnormal embryo size 3 | 220
embryonic lethality prior to o... 3 | 239
abnormal gait 2 | 69
embryonic growth retardation 2 | 106
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased basophil cell number 1 | 16
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating calcium ... 1 | 34
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
shortened QT interval 1 | 4

Disease

Carcinoma 61 | 11,493
ovarian cancer 52 | 8,520
osteosarcoma 48 | 7,950
medulloblastoma, large-cell 38 | 6,241
psoriasis 35 | 6,694
lung cancer 34 | 4,740
Autosomal recessive predisposition 31 | 1,442
glioblastoma 28 | 5,792
Cerebellar Ataxia 27 | 304
Acidosis, Lactic 25 | 97
Lactic acidemia 25 | 95
group 3 medulloblastoma 25 | 4,104
diabetes mellitus 24 | 1,728
Neuropathy 23 | 261
atypical teratoid / rhabdoid tumor 22 | 5,112
Cancer 21 | 2,499
ependymoma 21 | 4,679
Multiple myeloma 20 | 1,332
Breast cancer 19 | 3,578
Mitochondrial myopathy 19 | 26
Muscle hypotonia 19 | 571
Sensorineural Hearing Loss (disorder) 19 | 284
Blepharoptosis 18 | 231
Optic Atrophy 18 | 242
adult high grade glioma 18 | 3,801
Cognitive delay 17 | 608
Epilepsy 17 | 792
Global developmental delay 17 | 608
Heart failure 17 | 162
Leigh disease 17 | 100
Mental and motor retardation 17 | 608
Failure to gain weight 16 | 365
Myopathy 16 | 185
Pediatric failure to thrive 16 | 365
Peripheral Neuropathy 16 | 134
Schizophrenia 16 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
Short stature 15 | 531
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Lactic acidosis 14 | 51
Polyneuropathy 14 | 64
Ragged-red fibers 14 | 21
Seizures 14 | 596
lung adenocarcinoma 14 | 2,716
non-small cell lung cancer 14 | 2,890
Diabetes Mellitus, Non-Insulin-Dependent 13 | 145
Dystonia 13 | 164
Increased serum lactate 13 | 60
Mitochondrial Myopathies 13 | 21
astrocytic glioma 13 | 2,597
malignant mesothelioma 13 | 3,232
primitive neuroectodermal tumor 13 | 3,035
ulcerative colitis 13 | 1,819
Chronic progressive external ophthalmoplegia 12 | 26
Creatine phosphokinase serum increased 12 | 110
Depressive disorder 12 | 409
Dystonic disease 12 | 106
Elevated creatine kinase 12 | 110
Hypertensive disease 12 | 292
Leber hereditary optic neuropathy 12 | 14
Muscle Weakness 12 | 170
Obesity 12 | 678
oligodendroglioma 12 | 2,850
Blind spot located at fixation point 11 | 21
Cachexia 11 | 50
Cerebral atrophy 11 | 178
Decreased visual acuity, slowly progressive 11 | 13
Electrocardiogram abnormal 11 | 81
Hepatomegaly 11 | 285
MELAS syndrome 11 | 18
Mitochondrial respiratory chain defects 11 | 15
Ophthalmoplegia 11 | 106
Scotoma, Central 11 | 21
Slow decrease in visual acuity 11 | 13
colon cancer 11 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Brain Ischemia 10 | 110
Cardiac Arrhythmia 10 | 103
Conduction disorder of the heart 10 | 79
Congestive heart failure 10 | 113
Dementia 10 | 175
Developmental regression 10 | 95
Electrocardiogram change 10 | 78
Electromyogram abnormal 10 | 49
Highly variable severity 10 | 157
Hypoglycemia 10 | 152
Infantile onset 10 | 238
Loss of developmental milestones 10 | 95
Mental deterioration in childhood 10 | 95
Neurodegenerative disease 10 | 414
Neurodevelopmental regression 10 | 95
Pick disease 10 | 1,894
Psychomotor regression 10 | 95
Psychomotor regression beginning in infancy 10 | 95
Psychomotor regression in infants 10 | 95
Psychomotor regression, progressive 10 | 95
Variable expressivity 10 | 157
Vomiting 10 | 116
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
pancreatic cancer 10 | 2,398

Tissue

Endocrine System 102 | 18,159
Blood and immune system 100 | 16,909
Digestive Tract 100 | 17,369
Female tissues 100 | 17,400
Skin and soft tissues 100 | 17,230
Liver and Pancreas 99 | 16,750
Male tissues 99 | 17,142
Nervous System 99 | 16,725
Urinary Tract 99 | 16,678
Respiratory system 98 | 16,393
Cardiovascular System 96 | 15,192

Target Family

Enzyme 53 | 4,145
Non-IDG 39 | 12,091
Transcription Factor 4 | 1,400
Transporter 3 | 473
Kinase 2 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Mitochondrial nucleoid 104 | 104
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298