Development Level

Tdark 38 | 7,003
Tbio 17 | 10,625

IMPC Phenotype

embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
preweaning lethality, complete... 2 | 633
abnormal embryo size 1 | 112
decreased circulating glucose ... 1 | 121
embryonic growth retardation 1 | 28

Disease

ovarian cancer 34 | 8,491
osteosarcoma 22 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
lung cancer 13 | 4,473
Breast cancer 10 | 3,098
non primary Sjogren syndrome sicca 9 | 840
Multiple myeloma 8 | 1,327
non-small cell lung cancer 8 | 2,798
psoriasis 8 | 6,685
acute myeloid leukemia 6 | 785
glioblastoma 6 | 5,572
group 3 medulloblastoma 6 | 2,254
medulloblastoma, large-cell 6 | 6,234
colon cancer 5 | 1,475
pediatric high grade glioma 5 | 2,712
astrocytic glioma 4 | 2,241
atypical teratoid / rhabdoid tumor 4 | 4,369
lung adenocarcinoma 4 | 2,714
Mammary Neoplasms 3 | 410
breast carcinoma 3 | 1,614
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
invasive ductal carcinoma 3 | 2,950
nasopharyngeal carcinoma 3 | 1,056
primitive neuroectodermal tumor 3 | 3,031
sonic hedgehog group medulloblastoma 3 | 1,482
Brain glioma 2 | 10
Combined oxidative phosphorylation deficiency 2 | 8
Pick disease 2 | 1,893
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
cystic fibrosis 2 | 1,670
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,663
group 4 medulloblastoma 2 | 1,875
hereditary spastic paraplegia 2 | 313
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung carcinoma 2 | 2,844
posterior fossa group B ependymoma 2 | 1,530
Acquired metabolic disease 1 | 267
Allergic rhinitis 1 | 92
Amyotrophic lateral sclerosis type 5 1 | 14
Ankylosing spondylitis 1 | 138
Attention deficit hyperactivity disorder 1 | 156
Axonal neuropathy 1 | 17
Beckwith-Wiedemann syndrome 1 | 46
Cardiovascular system disease 1 | 194
Charcot-Marie-Tooth disease 1 | 74
DiGeorge syndrome 1 | 46
Diarrhea 1 | 155
Disease Progression 1 | 125
Down syndrome 1 | 548
Dyslexia 1 | 36
Enamel caries 1 | 8
Gastroenteritis 1 | 46
Gastroparesis 1 | 20
Gaucher disease type 1 1 | 171
Genital herpes 1 | 10
Gilles de la Tourette syndrome 1 | 47
Kidney papillary necrosis 1 | 2
Leber hereditary optic neuropathy 1 | 17
Leigh disease 1 | 81
Lymphoblastic lymphoma 1 | 2
Melanoma 1 | 261
Migraine Disorders 1 | 26
Mitochondrial DNA depletion syndrome 7 1 | 2
Mitochondrial Encephalomyopathies 1 | 11
Mouth Neoplasms 1 | 44
Multiple Sclerosis 1 | 498
Muscle Weakness 1 | 92
Neurodegenerative disease 1 | 383
Ophthalmoplegia 1 | 18
Optic atrophy 1 | 43
Osteoarthritis 1 | 96
Osteoporosis 1 | 259
Paraplegia 1 | 71
Schizophrenia 1 | 503
Silicosis 1 | 10
Specific language impairment 1 | 31
Squamous cell carcinoma 1 | 96
Stomach Neoplasms 1 | 282
Thoracic outlet syndrome 1 | 8
Thrombophilia 1 | 37
Velocardiofacial syndrome 1 | 45
Waldenstrons macroglobulinemia 1 | 764
adrenocortical carcinoma 1 | 1,427
atypical teratoid/rhabdoid tumor 1 | 1,095
ductal carcinoma in situ 1 | 1,745
gastric cancer 1 | 436
hepatocellular carcinoma 1 | 550
inflammatory breast cancer 1 | 404
medulloblastoma 1 | 1,524
nephrosclerosis 1 | 329
pilocytic astrocytoma 1 | 3,086
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
tuberculosis 1 | 1,563
tuberculosis and treatment for 6 months 1 | 686
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 55 | 17,994
Cardiovascular System 55 | 17,957
Digestive Tract 55 | 18,472
Endocrine System 55 | 18,511
Female tissues 55 | 18,646
Liver and Pancreas 55 | 18,135
Male tissues 55 | 17,968
Nervous System 55 | 18,560
Respiratory system 55 | 17,483
Urinary Tract 55 | 18,443
Skin and soft tissues 54 | 18,114

Target Family

Non-IDG 49 | 11,969
Enzyme 6 | 4,146

Compartment GO Term

Mitochondrial large ribosomal ... 55 | 55
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

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