Development Level

Tdark 37 | 6,588
Tbio 20 | 11,445

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 5 | 239
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
decreased NK T cell number 1 | 2
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased fasted circulating g... 1 | 76
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
preweaning lethality, incomple... 1 | 499
thick ventricular wall 1 | 7

Disease

ovarian cancer 35 | 8,520
osteosarcoma 23 | 7,950
lung cancer 14 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Carcinoma 11 | 11,493
Breast cancer 10 | 3,578
group 3 medulloblastoma 9 | 4,104
non primary Sjogren syndrome sicca 9 | 891
Multiple myeloma 8 | 1,332
non-small cell lung cancer 8 | 2,890
psoriasis 8 | 6,694
acute myeloid leukemia 6 | 783
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
atypical teratoid / rhabdoid tumor 5 | 5,112
colon cancer 5 | 1,478
pediatric high grade glioma 5 | 1,064
astrocytic glioma 4 | 2,597
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
Breast Neoplasms 3 | 445
Mammary Neoplasms 3 | 425
Retinitis pigmentosa 4 3 | 38
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
primitive neuroectodermal tumor 3 | 3,035
Brain glioma 2 | 7
Combined oxidative phosphorylation deficiency 2 | 14
Leigh disease 2 | 100
Melanoma 2 | 711
Pick disease 2 | 1,894
active Crohn's disease 2 | 922
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
hereditary spastic paraplegia 2 | 318
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Allergic rhinitis 1 | 94
Alzheimer's disease 1 | 658
Ankylosing spondylitis 1 | 140
Attention deficit hyperactivity disorder 1 | 278
Axonal neuropathy 1 | 27
Cardiomyopathy 1 | 116
Cardiovascular system disease 1 | 246
Charcot-Marie-Tooth disease 1 | 62
Diarrhea 1 | 253
Dilated cardiomyopathy 1 | 56
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Dyspnea 1 | 76
Elevated hepatic transaminases 1 | 81
Endometrial cancer 1 | 311
Failure to gain weight 1 | 365
Gaucher disease type 1 1 | 180
Hepatic enzyme increased 1 | 81
Hepatomegaly 1 | 285
Hyper-beta-alaninemia 1 | 9
Hypertrophic Cardiomyopathy 1 | 117
Increased blood alanine 1 | 9
Increased serum alanine 1 | 9
Increased serum lactate 1 | 60
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Mental Depression 1 | 333
Mitochondrial Encephalomyopathies 1 | 7
Mouth Neoplasms 1 | 55
Neurodegenerative disease 1 | 414
Ophthalmoplegia 1 | 106
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Paraplegia 1 | 74
Pediatric failure to thrive 1 | 365
Squamous cell carcinoma 1 | 129
Stomach Neoplasms 1 | 300
Subclinical abnormal liver function tests 1 | 81
Thrombophilia 1 | 38
Transaminases increased 1 | 81
Waldenstrons macroglobulinemia 1 | 765
Wilson-Turner syndrome 1 | 14
Wolcott-Rallison syndrome 1 | 10
adrenocortical carcinoma 1 | 1,428
hepatocellular carcinoma 1 | 547
inflammatory breast cancer 1 | 286
nephrosclerosis 1 | 333
posterior fossa group B ependymoma 1 | 416
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 56 | 16,909
Cardiovascular System 56 | 15,192
Digestive Tract 56 | 17,369
Endocrine System 56 | 18,159
Female tissues 56 | 17,400
Liver and Pancreas 56 | 16,750
Male tissues 56 | 17,142
Nervous System 56 | 16,725
Respiratory system 56 | 16,393
Skin and soft tissues 56 | 17,230
Urinary Tract 56 | 16,678

Target Family

Non-IDG 50 | 12,091
Enzyme 6 | 4,145
Kinase 1 | 634

Compartment GO Term

Mitochondrial large ribosomal ... 57 | 57
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
39S ribosomal protein L22, mitochondrial MRPL22 Tdark Non-IDG 0.70 0.21 64
Uncharacterized protein C2orf15 C2orf15 Tdark Non-IDG 1.32 0.05 16
39S ribosomal protein L45, mitochondrial MRPL45 Tdark Non-IDG 0.51 0.23 0
39S ribosomal protein L49, mitochondrial MRPL49 Tbio Non-IDG -2.76367 555.1 76
39S ribosomal protein L11, mitochondrial MRPL11 Tdark Non-IDG -0.63555 3.41 198
39S ribosomal protein L20, mitochondrial MRPL20 Tdark Non-IDG 1.23 0.05 48
39S ribosomal protein L32, mitochondrial MRPL32 Tdark Non-IDG 0.18 0.93 52
39S ribosomal protein L9, mitochondrial MRPL9 Tdark Non-IDG 1.00 0.05 133
39S ribosomal protein L14, mitochondrial MRPL14 Tdark Non-IDG 0.00000 79
39S ribosomal protein L54, mitochondrial MRPL54 Tdark Non-IDG 0.00000 120