Development Level

Tbio 7 | 10,625
Tchem 1 | 1,890

IMPC Phenotype

preweaning lethality, complete... 2 | 633
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased exploration in new e... 1 | 56

Disease

ovarian cancer 7 | 8,491
lung cancer 4 | 4,473
osteosarcoma 4 | 7,933
colon cancer 3 | 1,475
glioblastoma 3 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
malignant mesothelioma 3 | 3,163
oligodendroglioma 3 | 2,849
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
psoriasis 3 | 6,685
ulcerative colitis 3 | 2,087
Multiple myeloma 2 | 1,327
Polycystic Ovary Syndrome 2 | 334
Rheumatoid Arthritis 2 | 1,170
atypical teratoid / rhabdoid tumor 2 | 4,369
cystic fibrosis 2 | 1,670
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 2,514
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung adenocarcinoma 2 | 2,714
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung cancer 2 | 2,798
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
tuberculosis 2 | 1,563
Acute fatty liver of pregnancy 1 | 1
Alzheimer's disease 1 | 644
Breast cancer 1 | 3,098
Cardiomyopathy 1 | 110
Cardiovascular system disease 1 | 194
Cholestasis 1 | 93
Cleft Lip 1 | 91
Cleft palate 1 | 125
Clonorchiasis 1 | 15
Colorectal Cancer 1 | 62
Congenital heart disease 1 | 63
Congenital hemolytic anemia 1 | 31
Coronary heart disease 1 | 59
Degenerative polyarthritis 1 | 93
Disseminated intravascular coagulation 1 | 32
Down syndrome 1 | 548
Fanconi syndrome 1 | 14
Gaucher disease type 1 1 | 171
Hemorrhagic thrombocythemia 1 | 8
Hepatic encephalopathy 1 | 25
Hepatic vein thrombosis 1 | 8
Hepatitis E 1 | 11
Homocystinuria 1 | 23
Hyperhomocysteinemia 1 | 34
Hyperinsulinemic hypoglycemia 1 | 17
Hyperinsulinism 1 | 63
Hypoglycemia 1 | 81
Kidney disease 1 | 397
Liver disease 1 | 219
Long-chain 3-hydroxyl-CoA dehydrogenase deficiency 1 | 1
Malignant mesothelioma of pleura 1 | 7
Maternal acute fatty liver of pregnancy 1 | 1
Megaloblastic anemia 1 | 18
Methylmalonic acidemia 1 | 39
Mitochondrial trifunctional protein deficiency 1 | 3
Muscle Weakness 1 | 92
Myocardial Ischemia 1 | 169
Neural Tube Defects 1 | 31
Neural tube defect, folate-sensitive 1 | 4
Neural tube defects, folate-sensitive 1 | 4
Parkinson's disease 1 | 364
Patent foramen ovale 1 | 9
Pathological gambling 1 | 16
Placental abruption 1 | 16
Polycythemia 1 | 19
Reye syndrome 1 | 11
Substance-Related Disorders 1 | 114
Thrombotic thrombocytopenic purpura 1 | 14
Urethral obstruction 1 | 4
Waldenstrons macroglobulinemia 1 | 764
Zellweger Syndrome 1 | 38
active Crohn's disease 1 | 918
acute quadriplegic myopathy 1 | 1,157
aldosterone-producing adenoma 1 | 664
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
fructose-1,6-bisphosphatase deficiency 1 | 8
gastric carcinoma 1 | 832
hemolytic-uremic syndrome 1 | 28
hepatocellular carcinoma 1 | 550
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
medulloblastoma 1 | 1,524
mucosa-associated lymphoid tissue lymphoma 1 | 480
nephrosclerosis 1 | 329
neural tube defect 1 | 8
pancreatic carcinoma 1 | 567
pituitary cancer 1 | 1,972
pre-eclampsia 1 | 67
sonic hedgehog group medulloblastoma 1 | 1,482
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 8 | 17,994
Cardiovascular System 8 | 17,957
Digestive Tract 8 | 18,472
Endocrine System 8 | 18,511
Female tissues 8 | 18,646
Liver and Pancreas 8 | 18,135
Male tissues 8 | 17,968
Nervous System 8 | 18,560
Respiratory system 8 | 17,483
Skin and soft tissues 8 | 18,114
Urinary Tract 8 | 18,443

Target Family

Enzyme 5 | 4,146
Non-IDG 3 | 11,969

Compartment GO Term

Mitochondrial fatty acid beta-... 8 | 8
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Enoyl-CoA delta isomerase 1, mitochondrial ECI1 Tbio Enzyme -2.64081 426.7 199
C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 Tbio Enzyme -1.94079 82.5 84
Mitochondrial 10-formyltetrahydrofolate dehydrogenase ALDH1L2 Tbio Enzyme -0.94861 7.94 52
Trifunctional purine biosynthetic protein adenosine-3 GART Tchem Non-IDG -2.25256 171.9 117
Peroxisomal bifunctional enzyme EHHADH Tbio Non-IDG -2.02453 101.2 161
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.97935 948.2 132
Monofunctional C1-tetrahydrofolate synthase, mitochondrial MTHFD1L Tbio Enzyme -1.65041 42.3 94
Bisphosphoglycerate mutase BPGM Tbio Enzyme -1.26416 17.9 163