Development Level

Tbio 6 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal allantois morphology 1 | 8
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
embryonic lethality prior to t... 1 | 278

Disease

ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
lung cancer 4 | 4,740
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
malignant mesothelioma 3 | 3,232
osteosarcoma 3 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Multiple myeloma 2 | 1,332
Polycystic ovary syndrome 2 | 360
Rheumatoid arthritis 2 | 1,191
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
neural tube defect 2 | 9
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal amniotic fluid 1 | 6
Abnormal urinary amino-acid findings 1 | 38
Abnormality of metabolism/homeostasis 1 | 134
Acidosis, Lactic 1 | 97
Adenocarcinoma of lung 1 | 142
Adult Fanconi syndrome 1 | 12
Aminoaciduria 1 | 38
Bile duct adenoma 1 | 3
Budd-Chiari syndrome 1 | 12
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cardiovascular system disease 1 | 246
Chemical and Drug Induced Liver Injury 1 | 195
Cholecystitis 1 | 18
Cholelithiasis 1 | 33
Congenital heart disease 1 | 93
Congenital hemolytic anemia 1 | 32
Congestive heart failure 1 | 113
Degenerative polyarthritis 1 | 115
Disease Models, Animal 1 | 155
Disseminated intravascular coagulation 1 | 38
Elevated hepatic transaminases 1 | 81
Fanconi syndrome 1 | 14
Gaucher disease type 1 1 | 180
Generalized muscle weakness 1 | 57
Genu varum 1 | 29
Glycosuria 1 | 29
Heart failure 1 | 162
Hemolytic-Uremic Syndrome 1 | 30
Hepatic encephalopathy 1 | 27
Hepatic enzyme increased 1 | 81
Hepatitis E 1 | 11
Highly variable severity 1 | 157
Homocystinuria 1 | 21
Hydrops Fetalis 1 | 21
Hyperammonemia 1 | 30
Hyperhomocysteinemia 1 | 37
Hyperinsulinism 1 | 133
Hyperphosphaturia 1 | 21
Icterus 1 | 82
Lactic acidemia 1 | 95
Liver Dysfunction 1 | 99
Liver disease 1 | 237
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low Birth Weights 1 | 69
Malignant mesothelioma of pleura 1 | 7
Medium chain acyl-CoA dehydrogenase deficiency 1 | 13
Metabolic acidosis 1 | 90
Myoglobinuria 1 | 15
Neural Tube Defects 1 | 31
Neural tube defect, folate-sensitive 1 | 4
Neuropathy 1 | 261
Osteoarthritis 1 | 184
Patent foramen ovale 1 | 10
Pathological gambling 1 | 15
Peripheral Neuropathy 1 | 134
Placental abruption 1 | 18
Polycythemia 1 | 25
Pre-Eclampsia 1 | 68
Proteinuria 1 | 144
Respiratory Failure 1 | 104
Reye syndrome 1 | 11
Rhabdomyolysis 1 | 15
Rickets 1 | 49
Small for gestational age (disorder) 1 | 69
Subclinical abnormal liver function tests 1 | 81
Transaminases increased 1 | 81
Urethral obstruction 1 | 5
Variable expressivity 1 | 157
Very long chain acyl-CoA dehydrogenase deficiency 1 | 10
Zellweger syndrome 1 | 37

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 4 | 4,145
Non-IDG 3 | 12,091

Compartment GO Term

Mitochondrial fatty acid beta-... 7 | 7
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Enoyl-CoA delta isomerase 1, mitochondrial ECI1 Tbio Enzyme -2.67168 459.1 229
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.99704 989.4 151
Monofunctional C1-tetrahydrofolate synthase, mitochondrial MTHFD1L Tbio Enzyme -1.66972 40.2 102
Bisphosphoglycerate mutase BPGM Tbio Enzyme -1.29222 18.4 187
Peroxisomal bifunctional enzyme EHHADH Tbio Non-IDG -2.05616 109.3 204
Trifunctional purine biosynthetic protein adenosine-3 GART Tchem Non-IDG -2.26480 181.2 139
C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 Tbio Enzyme -1.97029 90.6 101