Development Level

Tbio 52 | 11,651
Tclin 14 | 612
Tchem 5 | 1,388
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal gait 2 | 69
embryonic lethality prior to o... 2 | 239
improved glucose tolerance 2 | 79
increased heart weight 2 | 62
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
aorta dilation 1 | 3
decreased basophil cell number 1 | 16
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
shortened QT interval 1 | 4

Disease

Carcinoma 37 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 30 | 8,520
medulloblastoma, large-cell 27 | 6,241
psoriasis 25 | 6,694
Cerebellar Ataxia 22 | 304
lung cancer 22 | 4,740
Autosomal recessive predisposition 21 | 1,442
Neuropathy 21 | 261
diabetes mellitus 21 | 1,728
Acidosis, Lactic 19 | 97
Lactic acidemia 19 | 95
Mitochondrial myopathy 19 | 26
group 3 medulloblastoma 19 | 4,104
glioblastoma 18 | 5,792
Sensorineural Hearing Loss (disorder) 17 | 284
atypical teratoid / rhabdoid tumor 17 | 5,112
Cancer 16 | 2,499
Leigh disease 16 | 100
Optic Atrophy 16 | 242
Blepharoptosis 15 | 231
Heart failure 15 | 162
Myopathy 15 | 185
Lactic acidosis 14 | 51
Peripheral Neuropathy 14 | 134
Polyneuropathy 14 | 64
Ragged-red fibers 14 | 21
Schizophrenia 14 | 1,160
Diabetes Mellitus, Non-Insulin-Dependent 13 | 145
Dystonia 13 | 164
adult high grade glioma 13 | 3,801
ependymoma 13 | 4,679
Depressive disorder 12 | 409
Dystonic disease 12 | 106
Epilepsy 12 | 792
Hypertensive disease 12 | 292
Leber hereditary optic neuropathy 12 | 14
Mitochondrial Myopathies 12 | 21
Obesity 12 | 678
Short stature 12 | 531
ulcerative colitis 12 | 1,819
Blind spot located at fixation point 11 | 21
Cachexia 11 | 50
Chronic progressive external ophthalmoplegia 11 | 26
Decreased visual acuity, slowly progressive 11 | 13
Electrocardiogram abnormal 11 | 81
Increased serum lactate 11 | 60
MELAS syndrome 11 | 18
Mitochondrial respiratory chain defects 11 | 15
Muscle Weakness 11 | 170
Muscle hypotonia 11 | 571
Ophthalmoplegia 11 | 106
Scotoma, Central 11 | 21
Seizures 11 | 596
Slow decrease in visual acuity 11 | 13
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
primitive neuroectodermal tumor 11 | 3,035
Abnormal vision 10 | 52
Blurred vision 10 | 19
Brain Ischemia 10 | 110
Cardiac Arrhythmia 10 | 103
Cardiac conduction abnormalities 10 | 78
Cerebral atrophy 10 | 178
Conduction disorder of the heart 10 | 79
Creatine phosphokinase serum increased 10 | 110
Dementia 10 | 175
EKG abnormalities 10 | 78
Electrocardiogram change 10 | 78
Electromyogram abnormal 10 | 49
Elevated creatine kinase 10 | 110
Failure to gain weight 10 | 365
Highly variable severity 10 | 157
Leber's optic atrophy 10 | 10
Neurodegenerative disease 10 | 414
Optic Atrophy, Hereditary, Leber 10 | 14
Pediatric failure to thrive 10 | 365
Retinal telangiectasia 10 | 12
Scotoma, Centrocecal 10 | 11
Tonic - clonic seizures 10 | 44
Tortuous retinal vessels 10 | 15
Variable expressivity 10 | 157
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Abdominal Pain 9 | 98
Cognitive delay 9 | 608
Developmental regression 9 | 95
Diabetes mellitus type 2 9 | 69
Encephalopathies 9 | 43
Fatigue 9 | 182
Global developmental delay 9 | 608
Infantile onset 9 | 238
Loss of developmental milestones 9 | 95
Mental and motor retardation 9 | 608
Mental deterioration in childhood 9 | 95
Neurodevelopmental regression 9 | 95
Psychomotor regression 9 | 95
Psychomotor regression beginning in infancy 9 | 95
Psychomotor regression in infants 9 | 95
Psychomotor regression, progressive 9 | 95

Tissue

Endocrine System 71 | 18,159
Female tissues 70 | 17,400
Skin and soft tissues 70 | 17,230
Blood and immune system 69 | 16,909
Digestive Tract 69 | 17,369
Liver and Pancreas 69 | 16,750
Male tissues 69 | 17,142
Nervous System 69 | 16,725
Urinary Tract 69 | 16,678
Respiratory system 68 | 16,393
Cardiovascular System 66 | 15,192

Target Family

Enzyme 34 | 4,145
Non-IDG 28 | 12,091
Transcription Factor 4 | 1,400
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Mitochondrial chromosome 73 | 73
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
Protein Mpv17 MPV17 Tbio Non-IDG -1.67807 47.6 134
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial SUCLG1 Tbio Enzyme -2.00981 99.0 78
Dimethyladenosine transferase 1, mitochondrial TFB1M Tbio Enzyme -1.46427 30.6 104
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Twinkle protein, mitochondrial TWNK Tbio Non-IDG -2.18726 156.1 146
Catenin alpha-2 CTNNA2 Tbio Non-IDG -1.98557 99.5 74
Humanin MT-RNR2 Tdark Non-IDG 0.00000 0
Mitofusin-1 MFN1 Tbio Non-IDG -2.10909 104.1 0