Development Level

Tbio 49 | 10,625
Tclin 12 | 602
Tchem 7 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 7 | 633
embryonic lethality prior to t... 3 | 187
abnormal embryo size 2 | 112
decreased rib number 2 | 59
embryonic lethality prior to o... 2 | 148
increased heart weight 2 | 37
abnormal behavior 1 | 226
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal kidney morphology 1 | 30
abnormal maxilla morphology 1 | 16
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placement of pupils 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal skin appearance 1 | 8
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
decreased circulating alanine ... 1 | 53
decreased circulating chloride... 1 | 32
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased heart weight 1 | 44
decreased startle reflex 1 | 48
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260

Disease

osteosarcoma 31 | 7,933
ovarian cancer 30 | 8,491
medulloblastoma, large-cell 27 | 6,234
psoriasis 24 | 6,685
lung cancer 23 | 4,473
glioblastoma 18 | 5,572
Mitochondrial myopathy 17 | 24
Neuropathy 17 | 210
atypical teratoid / rhabdoid tumor 17 | 4,369
Cancer 15 | 2,346
Leigh disease 15 | 81
ulcerative colitis 14 | 2,087
Leber hereditary optic neuropathy 13 | 17
Obesity 13 | 616
diabetes mellitus 13 | 1,663
Lactic acidosis 12 | 43
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
malignant mesothelioma 12 | 3,163
primitive neuroectodermal tumor 12 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
Chronic progressive external ophthalmoplegia 10 | 18
Leber's optic atrophy 10 | 10
Leigh syndrome 10 | 34
Neurodegenerative disease 10 | 383
Optic Atrophy, Hereditary, Leber 10 | 14
medulloblastoma 10 | 1,524
non-small cell lung cancer 10 | 2,798
pediatric high grade glioma 10 | 2,712
Alzheimer's disease 9 | 644
Diabetes mellitus type 2 9 | 69
Treatment Refractory Type 2 Diabetes Mellitus 9 | 53
ependymoma 9 | 2,514
group 3 medulloblastoma 9 | 2,254
interstitial cystitis 9 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
MELAS syndrome 8 | 17
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 8 | 9
Mitochondrial complex I deficiency 8 | 37
Multiple myeloma 8 | 1,327
Nonsyndromic deafness 8 | 121
lung adenocarcinoma 8 | 2,714
oligodendroglioma 8 | 2,849
pancreatic cancer 8 | 2,300
sonic hedgehog group medulloblastoma 8 | 1,482
Diabetes Mellitus, Experimental 7 | 106
Diabetes Mellitus, Non-Insulin-Dependent 7 | 161
Pearson syndrome 7 | 17
Peripheral Neuropathy 7 | 303
Stomach Neoplasms 7 | 282
adult high grade glioma 7 | 2,148
colon cancer 7 | 1,475
invasive ductal carcinoma 7 | 2,950
pilocytic astrocytoma 7 | 3,086
Breast cancer 6 | 3,098
Parkinson's disease 6 | 364
Pick disease 6 | 1,893
Prostatic Neoplasms 6 | 471
astrocytoma 6 | 1,493
cystic fibrosis 6 | 1,670
group 4 medulloblastoma 6 | 1,875
lung carcinoma 6 | 2,844
posterior fossa group A ependymoma 6 | 1,511
subependymal giant cell astrocytoma 6 | 2,287
Alpers syndrome 5 | 10
Atopic dermatitis 5 | 944
Heart failure 5 | 80
Hypertension 5 | 293
Hypertensive disease 5 | 193
Kidney disease 5 | 397
Malaria 5 | 140
Mammary Neoplasms 5 | 410
Mitochondrial Complex 1 Deficiency 5 | 28
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome 5 | 5
Myopathy 5 | 128
Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 1 5 | 5
Rheumatoid Arthritis 5 | 1,170
Sensorineural hearing loss 5 | 107
Vascular disease 5 | 281
astrocytic glioma 5 | 2,241
breast carcinoma 5 | 1,614
nasopharyngeal carcinoma 5 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Adenoma 4 | 165
Amyotrophic Lateral Sclerosis 4 | 432
Arthritis 4 | 248
Atherosclerosis 4 | 275
Cerebrovascular disease 4 | 231
Colonic Neoplasms 4 | 126
Coronary artery disease 4 | 240
Heart disease 4 | 279
Male infertility 4 | 170
Metabolic syndrome X 4 | 155
Methylmalonic acidemia 4 | 39
Mitochondrial Diseases 4 | 9
Pancreatic Neoplasm 4 | 79
acute quadriplegic myopathy 4 | 1,157
adrenocortical carcinoma 4 | 1,427
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
tuberculosis 4 | 1,563

Tissue

Blood and immune system 69 | 17,994
Cardiovascular System 69 | 17,957
Digestive Tract 69 | 18,472
Endocrine System 69 | 18,511
Female tissues 69 | 18,646
Nervous System 69 | 18,560
Skin and soft tissues 69 | 18,114
Urinary Tract 69 | 18,443
Liver and Pancreas 68 | 18,135
Male tissues 68 | 17,968
Respiratory system 67 | 17,483

Target Family

Enzyme 33 | 4,146
Non-IDG 27 | 11,969
Transcription Factor 4 | 1,400
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

Compartment GO Term

Mitochondrial chromosome 71 | 71
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Mpv17 MPV17 Tbio Non-IDG -1.63162 40.5 114
Pendrin SLC26A4 Tbio Transporter -2.65903 426.8 96
Catenin alpha-2 CTNNA2 Tbio Non-IDG -1.97005 96.0 66
Twinkle protein, mitochondrial TWNK Tbio Non-IDG -2.15938 144.6 127
Pre-B-cell leukemia transcription factor 2 PBX2 Tbio Transcription Factor -1.87943 70.2 152
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tchem Kinase -2.75634 590.2 473
Secreted protein C10orf99 C10orf99 Tbio Non-IDG -1.80584 63.7 3
Thymidine phosphorylase TYMP Tclin Enzyme -2.82420 666.7 283
Mitochondrial-derived peptide MOTS-c MT-RNR1 Tbio Non-IDG 0.00000 0
Cytochrome c oxidase subunit 3 MT-CO3 Tbio Enzyme -3.40472 2347.9 83