Development Level

Tbio 126 | 11,445
Tdark 28 | 6,588
Tchem 22 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 10 | 499
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 6 | 278
abnormal behavior 5 | 298
abnormal embryo size 5 | 220
decreased total body fat amoun... 5 | 207
short tibia 5 | 97
increased circulating alkaline... 4 | 122
increased mean corpuscular hem... 4 | 96
increased total body fat amoun... 4 | 134
abnormal bone structure 3 | 187
abnormal retina morphology 3 | 71
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 53
decreased circulating serum al... 3 | 82
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased fasted circulating g... 3 | 76
increased neutrophil cell numb... 3 | 46
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal embryo turning 2 | 31
abnormal kidney morphology 2 | 65
abnormal skin morphology 2 | 50
cataract 2 | 92
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased hematocrit 2 | 46
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal lip morphology 1 | 2
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased brain size 1 | 4
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
edema 1 | 59
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 115 | 11,493
ovarian cancer 109 | 8,520
osteosarcoma 87 | 7,950
medulloblastoma, large-cell 82 | 6,241
glioblastoma 81 | 5,792
atypical teratoid / rhabdoid tumor 69 | 5,112
lung cancer 61 | 4,740
group 3 medulloblastoma 59 | 4,104
psoriasis 57 | 6,694
ependymoma 55 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,291
adult high grade glioma 54 | 3,801
primitive neuroectodermal tumor 50 | 3,035
Breast cancer 46 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,989
invasive ductal carcinoma 43 | 2,951
malignant mesothelioma 38 | 3,232
non-small cell lung cancer 38 | 2,890
Cancer 37 | 2,499
pancreatic cancer 37 | 2,398
Astrocytoma, Pilocytic 36 | 3,081
Kidney cancer 35 | 2,613
oligodendroglioma 33 | 2,850
lung adenocarcinoma 31 | 2,716
breast carcinoma 30 | 1,638
adrenocortical carcinoma 28 | 1,428
ductal carcinoma in situ 28 | 1,745
Multiple myeloma 26 | 1,332
colon cancer 26 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
astrocytic glioma 25 | 2,597
lung carcinoma 25 | 2,843
subependymal giant cell astrocytoma 25 | 2,287
tuberculosis 22 | 2,010
Atopic dermatitis 21 | 952
ulcerative colitis 21 | 1,819
Pick disease 20 | 1,894
group 4 medulloblastoma 20 | 1,855
interstitial cystitis 20 | 2,312
nasopharyngeal carcinoma 20 | 1,058
Endometriosis 19 | 540
acute quadriplegic myopathy 19 | 1,158
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Intellectual disability 18 | 1,016
Waldenstrons macroglobulinemia 17 | 765
astrocytoma 17 | 1,146
diabetes mellitus 16 | 1,728
juvenile dermatomyositis 15 | 1,187
pituitary cancer 15 | 1,972
primary pancreatic ductal adenocarcinoma 15 | 1,109
Autosomal recessive predisposition 14 | 1,442
progressive supranuclear palsy 14 | 676
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
Rheumatoid arthritis 13 | 1,191
pediatric high grade glioma 12 | 1,064
primary Sjogren syndrome 12 | 735
spina bifida 12 | 1,074
dermatomyositis 11 | 966
non primary Sjogren syndrome sicca 11 | 891
Breast Neoplasms 9 | 445
Obesity 9 | 678
active Crohn's disease 9 | 922
Bipolar Disorder 8 | 666
Liver Cirrhosis, Experimental 8 | 769
Mammary Neoplasms 8 | 425
Microcephaly 8 | 166
Schizophrenia 8 | 1,160
esophageal adenocarcinoma 8 | 737
gastric carcinoma 8 | 807
medulloblastoma 8 | 720
posterior fossa group A ependymoma 8 | 468
Duchenne muscular dystrophy 7 | 601
Nystagmus 7 | 317
Vascular disease 7 | 319
acute myeloid leukemia 7 | 783
cystic fibrosis 7 | 1,696
sonic hedgehog group medulloblastoma 7 | 467
Cataract 6 | 297
Melanoma 6 | 711
Neurodegenerative disease 6 | 414
Paraplegia 6 | 74
Renal Cell Carcinoma 6 | 214
cutaneous lupus erythematosus 6 | 1,057
hereditary spastic paraplegia 6 | 318
tuberculosis and treatment for 6 months 6 | 409
Cognitive delay 5 | 608
Down syndrome 5 | 499
Global developmental delay 5 | 608
Lens Opacities 5 | 231
Mental and motor retardation 5 | 608
Retinitis Pigmentosa 5 | 226
Small head 5 | 374
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
chronic rhinosinusitis 5 | 512
fibroadenoma 5 | 559

Tissue

Endocrine System 173 | 18,159
Digestive Tract 172 | 17,369
Blood and immune system 171 | 16,909
Female tissues 171 | 17,400
Male tissues 171 | 17,142
Nervous System 171 | 16,725
Skin and soft tissues 171 | 17,230
Urinary Tract 171 | 16,678
Liver and Pancreas 170 | 16,750
Respiratory system 168 | 16,393
Cardiovascular System 166 | 15,192

Target Family

Non-IDG 118 | 12,091
Enzyme 38 | 4,145
Kinase 13 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 2 | 344
Transporter 1 | 473
oGPCR 1 | 421

Compartment GO Term

Midbody 178 | 178
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Tetratricopeptide repeat protein 19, mitochondrial TTC19 Tbio Non-IDG -0.95371 10.6 38
MIT domain-containing protein 1 MITD1 Tbio Non-IDG -0.25556 2.10 59
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Zinc finger protein 330 ZNF330 Tdark Non-IDG -0.41913 3.06 28
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99