Development Level

Tbio 140 | 11,445
Tdark 57 | 6,588
Tchem 26 | 1,598
Tclin 10 | 613

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 9 | 499
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating free fat... 3 | 31
decreased circulating glucose ... 3 | 126
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased startle reflex 3 | 112
small superior vagus ganglion 3 | 74
abnormal behavioral response t... 2 | 66
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal gait 2 | 69
abnormal joint morphology 2 | 23
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased KLRG1+ CD4 alpha bet... 2 | 5
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating sodium l... 2 | 22
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal iris pigmentation 1 | 4
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal skin pigmentation 1 | 1
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
brachydactyly 1 | 19
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating lipase l... 1 | 3
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged kidney 1 | 14
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating lipase l... 1 | 3
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
pallor 1 | 34
prenatal lethality 1 | 28
prolonged QRS complex duration 1 | 8
small kidney 1 | 16
syndactyly 1 | 23
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 148 | 11,493
ovarian cancer 134 | 8,520
osteosarcoma 105 | 7,950
medulloblastoma, large-cell 94 | 6,241
glioblastoma 91 | 5,792
ependymoma 80 | 4,679
psoriasis 80 | 6,694
atypical teratoid / rhabdoid tumor 79 | 5,112
lung cancer 76 | 4,740
adult high grade glioma 71 | 3,801
group 3 medulloblastoma 62 | 4,104
Breast cancer 56 | 3,578
malignant mesothelioma 56 | 3,232
non-small cell lung cancer 55 | 2,890
primitive neuroectodermal tumor 48 | 3,035
oligodendroglioma 47 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,989
subependymal giant cell astrocytoma 40 | 2,287
Astrocytoma, Pilocytic 39 | 3,081
astrocytic glioma 39 | 2,597
interstitial cystitis 37 | 2,312
lung carcinoma 37 | 2,843
Pick disease 36 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
invasive ductal carcinoma 36 | 2,951
lung adenocarcinoma 35 | 2,716
pancreatic cancer 34 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
colon cancer 30 | 1,478
pituitary cancer 30 | 1,972
Kidney cancer 29 | 2,613
adrenocortical carcinoma 27 | 1,428
Multiple myeloma 25 | 1,332
group 4 medulloblastoma 25 | 1,855
Autosomal recessive predisposition 24 | 1,442
tuberculosis 24 | 2,010
breast carcinoma 23 | 1,638
Cancer 22 | 2,499
ductal carcinoma in situ 21 | 1,745
nasopharyngeal carcinoma 21 | 1,058
spina bifida 21 | 1,074
Intellectual disability 20 | 1,016
cystic fibrosis 20 | 1,696
juvenile dermatomyositis 20 | 1,187
diabetes mellitus 19 | 1,728
progressive supranuclear palsy 19 | 676
primary pancreatic ductal adenocarcinoma 17 | 1,109
acute quadriplegic myopathy 16 | 1,158
ulcerative colitis 16 | 1,819
active Crohn's disease 15 | 922
Atopic dermatitis 14 | 952
medulloblastoma 14 | 720
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
astrocytoma 13 | 1,146
dermatomyositis 13 | 966
Epilepsy 12 | 792
Rheumatoid arthritis 12 | 1,191
cutaneous lupus erythematosus 12 | 1,057
non primary Sjogren syndrome sicca 12 | 891
Bipolar Disorder 11 | 666
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Seizures 11 | 596
Waldenstrons macroglobulinemia 11 | 765
gastric carcinoma 11 | 807
pediatric high grade glioma 11 | 1,064
posterior fossa group A ependymoma 11 | 468
Carcinoma of breast 10 | 11
Lissencephaly 10 | 69
Malignant tumor of ovary 10 | 25
Melanoma 10 | 711
Metastatic Breast Carcinoma 10 | 21
Metastatic Prostate Carcinoma 10 | 18
Neuroblastoma 10 | 80
fibroadenoma 10 | 559
hepatocellular carcinoma 10 | 547
transitional cell carcinoma 10 | 22
Alzheimer's disease 9 | 658
Breast Neoplasms 9 | 445
Duchenne muscular dystrophy 9 | 601
Endometriosis 9 | 540
HER2-positive carcinoma of breast 9 | 21
Kaposi's sarcoma 9 | 22
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Mammary Neoplasms 9 | 425
Nephroblastoma 9 | 51
Ocular hypertension 9 | 42
Rhabdomyosarcoma 9 | 39
Schizophrenia 9 | 1,160
Secondary malignant neoplasm of pancreas 9 | 10
active ulcerative colitis 9 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
sonic hedgehog group medulloblastoma 9 | 467

Tissue

Endocrine System 233 | 18,159
Female tissues 232 | 17,400
Digestive Tract 231 | 17,369
Male tissues 231 | 17,142
Nervous System 230 | 16,725
Urinary Tract 230 | 16,678
Skin and soft tissues 229 | 17,230
Liver and Pancreas 228 | 16,750
Respiratory system 226 | 16,393
Blood and immune system 225 | 16,909
Cardiovascular System 223 | 15,192

Target Family

Non-IDG 161 | 12,091
Enzyme 44 | 4,145
Transcription Factor 12 | 1,400
Kinase 8 | 634
Transporter 5 | 473
Ion Channel 2 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Microtubules 233 | 233
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Potassium voltage-gated channel subfamily E member 4 KCNE4 Tbio Ion Channel -1.17671 15.9 99
MAP7 domain-containing protein 1 MAP7D1 Tdark Non-IDG 0.27 0.84 52
Huntingtin-interacting protein K HYPK Tbio Non-IDG -0.84672 8.89 4
Calcyphosin-like protein CAPSL Tdark Non-IDG -0.31087 1.84 28
Cytoskeleton-associated protein 2 CKAP2 Tbio Non-IDG -2.30784 205.9 84
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 Tbio Enzyme -0.79764 6.35 32
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118