Development Level

Tbio 130 | 11,178
Tdark 26 | 6,569
Tchem 14 | 1,885
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to t... 8 | 278
preweaning lethality, incomple... 7 | 499
decreased body length 5 | 101
decreased total body fat amoun... 5 | 207
male infertility 5 | 123
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
decreased bone mineral content 4 | 151
embryonic growth retardation 4 | 106
increased circulating alkaline... 4 | 122
abnormal embryo turning 3 | 31
abnormal head morphology 3 | 10
abnormal humerus morphology 3 | 11
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
edema 3 | 59
prenatal lethality prior to he... 3 | 87
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal pericardium morpholog... 2 | 26
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
abnormal brain morphology 1 | 13
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart looping 1 | 5
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating fructosa... 1 | 30
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
hydroencephaly 1 | 14
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale liver 1 | 6
prenatal lethality 1 | 28
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 134 | 11,192
ovarian cancer 93 | 8,297
osteosarcoma 84 | 7,766
group 3 medulloblastoma 57 | 4,002
psoriasis 57 | 6,514
medulloblastoma, large-cell 53 | 6,086
ependymoma 52 | 4,559
glioblastoma 48 | 5,635
atypical teratoid / rhabdoid tumor 45 | 4,971
lung cancer 45 | 4,607
Kidney cancer 41 | 2,548
malignant mesothelioma 39 | 3,135
adult high grade glioma 35 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,204
primitive neuroectodermal tumor 34 | 2,957
Breast cancer 31 | 3,469
Intellectual disability 30 | 998
Autosomal recessive predisposition 29 | 1,407
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,902
adrenocortical carcinoma 26 | 1,385
non-small cell lung cancer 25 | 2,799
oligodendroglioma 24 | 2,768
Pick disease 23 | 1,856
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,872
Astrocytoma, Pilocytic 22 | 3,006
invasive ductal carcinoma 22 | 2,867
astrocytic glioma 21 | 2,530
Cancer 20 | 2,388
Dull intelligence 20 | 634
Low intelligence 20 | 634
Mental Retardation 20 | 634
Mental deficiency 20 | 634
Poor school performance 20 | 634
Microcephaly 18 | 166
lung adenocarcinoma 18 | 2,627
Cognitive delay 17 | 596
Global developmental delay 17 | 596
Mental and motor retardation 17 | 596
colon cancer 17 | 1,428
group 4 medulloblastoma 17 | 1,806
lung carcinoma 17 | 2,755
pancreatic cancer 17 | 2,322
tuberculosis 17 | 1,963
Ciliopathy 16 | 71
ductal carcinoma in situ 16 | 1,686
nasopharyngeal carcinoma 16 | 1,024
posterior fossa group B ependymoma 16 | 406
ulcerative colitis 16 | 1,765
Polydactyly 15 | 106
Atopic dermatitis 14 | 915
Joubert syndrome 14 | 66
Short stature 14 | 514
Small head 14 | 366
subependymal giant cell astrocytoma 14 | 2,230
breast carcinoma 13 | 1,589
Nystagmus 12 | 309
interstitial cystitis 12 | 2,237
Epilepsy 11 | 775
Seizures 11 | 584
chronic rhinosinusitis 11 | 505
pituitary cancer 11 | 1,915
Congenital hypoplasia of penis 10 | 168
Nephronophthisis 10 | 79
Obesity 10 | 655
Rheumatoid arthritis 10 | 1,156
Schizophrenia 10 | 1,136
diabetes mellitus 10 | 1,683
non primary Sjogren syndrome sicca 10 | 861
progressive supranuclear palsy 10 | 656
tuberculosis and treatment for 6 months 10 | 399
Amyotrophic lateral sclerosis 9 | 437
Bardet-Biedl syndrome 9 | 51
Endometriosis 9 | 521
Retinitis Pigmentosa 9 | 223
Seckel syndrome 9 | 34
active Crohn's disease 9 | 882
astrocytoma 9 | 1,113
primary Sjogren syndrome 9 | 710
Asphyxiating thoracic dystrophy 8 | 44
Electroretinogram abnormal 8 | 94
Glaucoma 8 | 232
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 8 | 16
pediatric high grade glioma 8 | 1,035
Abnormality of retinal pigmentation 7 | 109
Cerebellar Ataxia 7 | 302
Cystic kidney disease 7 | 25
Hypertensive disease 7 | 278
Increase in blood pressure 7 | 118
Low Vision 7 | 167
Meckel syndrome 7 | 46
Retinal Degeneration 7 | 103
Retinal pigment epithelial abnormality 7 | 109
Sloping forehead 7 | 46
Visual Impairment 7 | 167
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,911
Cataract 6 | 290
Muscle hypotonia 6 | 562
dermatomyositis 6 | 941
gastric cancer 6 | 445
primary pancreatic ductal adenocarcinoma 6 | 1,071

Tissue

Endocrine System 167 | 18,159
Female tissues 166 | 17,400
Male tissues 165 | 17,142
Digestive Tract 164 | 17,369
Skin and soft tissues 164 | 17,230
Blood and immune system 162 | 16,909
Liver and Pancreas 162 | 16,750
Nervous System 162 | 16,725
Respiratory system 162 | 16,393
Urinary Tract 162 | 16,678
Cardiovascular System 156 | 15,192

Target Family

Non-IDG 141 | 12,091
Enzyme 19 | 4,145
Kinase 11 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Microtubule organizing center ... 173 | 173
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrobin CNTROB Tbio Non-IDG -1.31192 23.3 151
Centrosomal protein of 104 kDa CEP104 Tbio Non-IDG -1.23064 17.5 69
Centriole, cilia and spindle-associated protein CCSAP Tbio Non-IDG -1.93256 89.5 55
Protein SFI1 homolog SFI1 Tdark Non-IDG -1.48977 32.1 21
Centrosomal protein of 192 kDa CEP192 Tbio Non-IDG -1.15560 13.3 34
Heat shock 70 kDa protein 6 HSPA6 Tchem Non-IDG -1.75259 92.5 173
Tau-tubulin kinase 2 TTBK2 Tbio Kinase -1.26107 19.5 146
SCL-interrupting locus protein STIL Tbio Non-IDG -1.99386 94.6 49
StAR-related lipid transfer protein 9 STARD9 Tbio Non-IDG -0.69167 5.48 21
Fas-binding factor 1 FBF1 Tbio Non-IDG 0.00000 27