Development Level

Tbio 113 | 10,625
Tdark 27 | 7,003
Tchem 18 | 1,890
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to t... 6 | 187
abnormal behavior 5 | 226
decreased bone mineral content 5 | 157
decreased lean body mass 5 | 195
decreased total body fat amoun... 5 | 186
hyperactivity 4 | 108
increased mean corpuscular hem... 4 | 93
increased or absent threshold ... 4 | 128
abnormal head morphology 3 | 10
decreased body length 3 | 108
decreased body weight 3 | 174
decreased circulating choleste... 3 | 85
preweaning lethality, incomple... 3 | 260
abnormal bone structure 2 | 131
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal embryo turning 2 | 15
abnormal humerus morphology 2 | 11
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 33
decreased circulating glucose ... 2 | 121
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
embryonic growth retardation 2 | 28
hypoactivity 2 | 89
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal brain morphology 1 | 6
abnormal craniofacial morpholo... 1 | 12
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 20
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal tail morphology 1 | 17
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased basophil cell number 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating fructosa... 1 | 31
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lactate dehydrogenas... 1 | 14
decreased lumbar vertebrae num... 1 | 62
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
edema 1 | 11
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
hydroencephaly 1 | 6
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased CD8-positive, naive ... 1 | 3
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glycerol... 1 | 11
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
pale liver 1 | 5
polydactyly 1 | 22
prenatal lethality 1 | 16
short tibia 1 | 82
vertebral fusion 1 | 23

Disease

ovarian cancer 86 | 8,484
osteosarcoma 81 | 7,933
psoriasis 55 | 6,685
medulloblastoma, large-cell 54 | 6,234
glioblastoma 46 | 5,572
lung cancer 39 | 4,466
malignant mesothelioma 37 | 3,162
atypical teratoid / rhabdoid tumor 35 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
primitive neuroectodermal tumor 34 | 3,031
group 3 medulloblastoma 33 | 2,254
Carcinoma 32 | 2,147
posterior fossa group B ependymoma 31 | 1,530
Breast cancer 29 | 3,094
pediatric high grade glioma 29 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
adrenocortical carcinoma 25 | 1,427
ependymoma 24 | 2,514
non-small cell lung cancer 24 | 2,798
pilocytic astrocytoma 23 | 3,086
Cancer 22 | 2,346
Pick disease 22 | 1,893
oligodendroglioma 22 | 2,849
invasive ductal carcinoma 21 | 2,950
colon cancer 20 | 1,475
group 4 medulloblastoma 19 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
Intellectual disability 18 | 573
astrocytic glioma 18 | 2,241
lung adenocarcinoma 18 | 2,713
nasopharyngeal carcinoma 18 | 1,056
pancreatic cancer 18 | 2,300
Microcephaly 17 | 149
ductal carcinoma in situ 17 | 1,745
sonic hedgehog group medulloblastoma 17 | 1,482
ulcerative colitis 17 | 2,087
Atopic dermatitis 15 | 944
lung carcinoma 15 | 2,844
Joubert syndrome 13 | 61
breast carcinoma 13 | 1,614
posterior fossa group A ependymoma 13 | 1,511
subependymal giant cell astrocytoma 13 | 2,287
tuberculosis 13 | 1,557
Ciliopathy 12 | 57
Polydactyly 12 | 93
adult high grade glioma 12 | 2,148
interstitial cystitis 12 | 2,299
progressive supranuclear palsy 12 | 674
Nephronophthisis 11 | 74
astrocytoma 11 | 1,493
tuberculosis and treatment for 6 months 11 | 686
Endometriosis 10 | 535
chronic rhinosinusitis 10 | 512
non primary Sjogren syndrome sicca 10 | 840
Rheumatoid Arthritis 9 | 1,160
atypical teratoid/rhabdoid tumor 9 | 1,095
medulloblastoma 9 | 1,524
pituitary cancer 9 | 1,972
Bardet-Biedl Syndrome 8 | 40
Obesity 8 | 616
Seckel syndrome 8 | 34
diabetes mellitus 8 | 1,663
primary Sjogren syndrome 8 | 789
Asphyxiating thoracic dystrophy 7 | 32
Meckel syndrome 7 | 48
active Crohn's disease 7 | 918
Amyotrophic Lateral Sclerosis 6 | 431
Cystic kidney disease 6 | 25
IGA Glomerulonephritis 6 | 454
Neurodegenerative disease 6 | 383
Orofaciodigital syndrome 6 | 19
Paraplegia 6 | 71
Prostate cancer 6 | 172
Retinitis pigmentosa 6 | 153
Schizophrenia 6 | 501
Senior-Loken syndrome 6 | 21
gastric cancer 6 | 430
pancreatic carcinoma 6 | 567
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primary pancreatic ductal adenocarcinoma 6 | 1,271
Parkinson's disease 5 | 364
Polycystic kidney disease 5 | 54
acute quadriplegic myopathy 5 | 1,157
aldosterone-producing adenoma 5 | 664
dermatomyositis 5 | 933
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 532
spina bifida 5 | 1,064
Hydrolethalus syndrome 4 | 128
Leber congenital amaurosis 4 | 72
Mammary Neoplasms 4 | 410
Mammary Neoplasms, Experimental 4 | 150
Peripheral Neuropathy 4 | 303
Primary ciliary dyskinesia 4 | 73
Prostatic Neoplasms 4 | 471
Renal Cell Carcinoma 4 | 199
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 477
acute myeloid leukemia 4 | 780
inflammatory breast cancer 4 | 404

Tissue

Male tissues 155 | 17,969
Blood and immune system 154 | 17,995
Cardiovascular System 154 | 17,958
Digestive Tract 154 | 18,473
Endocrine System 154 | 18,512
Female tissues 154 | 18,647
Liver and Pancreas 154 | 18,136
Nervous System 154 | 18,561
Respiratory system 153 | 17,484
Urinary Tract 153 | 18,444
Skin and soft tissues 152 | 18,115

Target Family

Non-IDG 128 | 11,971
Enzyme 19 | 4,146
Kinase 12 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Microtubule organizing center ... 161 | 161
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.72231 55.8 158
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Coiled-coil domain-containing protein 92 CCDC92 Tdark Non-IDG 0.08 0.73 76
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23739 18.0 90
Coiled-coil domain-containing protein 14 CCDC14 Tbio Non-IDG 0.39 0.36 23
Serine/threonine-protein kinase Nek2 NEK2 Tchem Kinase -2.11711 141.2 305
Coiled-coil domain-containing protein 146 CCDC146 Tdark Non-IDG 0.90 0.11 67
Coiled-coil domain-containing protein 13 CCDC13 Tbio Non-IDG 0.70 0.64 56
GTP-binding nuclear protein Ran RAN Tbio Enzyme -2.52041 303.8 437