Development Level

Tbio 134 | 11,651
Tdark 26 | 6,593
Tchem 14 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to t... 8 | 278
preweaning lethality, incomple... 8 | 499
decreased body length 5 | 101
decreased total body fat amoun... 5 | 207
male infertility 5 | 123
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
decreased bone mineral content 4 | 151
embryonic growth retardation 4 | 106
increased circulating alkaline... 4 | 122
abnormal embryo turning 3 | 31
abnormal head morphology 3 | 10
abnormal humerus morphology 3 | 11
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
edema 3 | 59
prenatal lethality prior to he... 3 | 87
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal pericardium morpholog... 2 | 26
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
abnormal brain morphology 1 | 13
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart looping 1 | 5
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
hydroencephaly 1 | 14
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale liver 1 | 6
prenatal lethality 1 | 28
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 137 | 11,493
ovarian cancer 95 | 8,520
osteosarcoma 86 | 7,950
group 3 medulloblastoma 59 | 4,104
psoriasis 59 | 6,694
medulloblastoma, large-cell 56 | 6,241
ependymoma 55 | 4,679
glioblastoma 50 | 5,792
lung cancer 49 | 4,740
atypical teratoid / rhabdoid tumor 46 | 5,112
Kidney cancer 42 | 2,613
malignant mesothelioma 40 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,291
adult high grade glioma 36 | 3,801
primitive neuroectodermal tumor 36 | 3,035
Breast cancer 35 | 3,578
Intellectual disability 30 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
Autosomal recessive predisposition 29 | 1,442
adrenocortical carcinoma 28 | 1,428
non-small cell lung cancer 28 | 2,890
oligodendroglioma 25 | 2,850
Pick disease 24 | 1,894
Astrocytoma, Pilocytic 23 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
invasive ductal carcinoma 23 | 2,951
Cancer 22 | 2,499
astrocytic glioma 21 | 2,597
Dull intelligence 20 | 645
Low intelligence 20 | 645
Mental Retardation 20 | 645
Mental deficiency 20 | 645
Poor school performance 20 | 645
lung adenocarcinoma 20 | 2,716
colon cancer 19 | 1,478
group 4 medulloblastoma 19 | 1,855
Microcephaly 18 | 166
ductal carcinoma in situ 18 | 1,745
nasopharyngeal carcinoma 18 | 1,058
pancreatic cancer 18 | 2,398
tuberculosis 18 | 2,010
Cognitive delay 17 | 608
Global developmental delay 17 | 608
Mental and motor retardation 17 | 608
lung carcinoma 17 | 2,843
Ciliopathy 16 | 71
posterior fossa group B ependymoma 16 | 416
subependymal giant cell astrocytoma 16 | 2,287
ulcerative colitis 16 | 1,819
Atopic dermatitis 15 | 952
Polydactyly 15 | 107
breast carcinoma 15 | 1,638
Joubert syndrome 14 | 66
Short stature 14 | 531
Small head 14 | 374
Nystagmus 12 | 317
Schizophrenia 12 | 1,160
interstitial cystitis 12 | 2,312
progressive supranuclear palsy 12 | 676
Epilepsy 11 | 792
Seizures 11 | 596
chronic rhinosinusitis 11 | 512
pituitary cancer 11 | 1,972
Congenital hypoplasia of penis 10 | 176
Endometriosis 10 | 540
Nephronophthisis 10 | 80
Obesity 10 | 678
Rheumatoid arthritis 10 | 1,191
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
non primary Sjogren syndrome sicca 10 | 891
tuberculosis and treatment for 6 months 10 | 409
Amyotrophic lateral sclerosis 9 | 451
Bardet-Biedl syndrome 9 | 51
Retinitis Pigmentosa 9 | 226
Seckel syndrome 9 | 34
active Crohn's disease 9 | 922
primary Sjogren syndrome 9 | 735
Asphyxiating thoracic dystrophy 8 | 44
Electroretinogram abnormal 8 | 95
Glaucoma 8 | 239
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 8 | 16
pediatric high grade glioma 8 | 1,064
Abnormality of retinal pigmentation 7 | 111
Cerebellar Ataxia 7 | 304
Cystic kidney disease 7 | 26
Hypertensive disease 7 | 292
Increase in blood pressure 7 | 119
Liver cancer 7 | 604
Low Vision 7 | 174
Meckel syndrome 7 | 46
Retinal Degeneration 7 | 106
Retinal pigment epithelial abnormality 7 | 111
Sloping forehead 7 | 46
Visual Impairment 7 | 174
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Cataract 6 | 297
dermatomyositis 6 | 966
gastric cancer 6 | 459
primary pancreatic ductal adenocarcinoma 6 | 1,109

Tissue

Endocrine System 170 | 18,159
Female tissues 169 | 17,400
Male tissues 168 | 17,142
Digestive Tract 167 | 17,369
Skin and soft tissues 167 | 17,230
Blood and immune system 165 | 16,909
Liver and Pancreas 165 | 16,750
Nervous System 165 | 16,725
Respiratory system 165 | 16,393
Urinary Tract 165 | 16,678
Cardiovascular System 159 | 15,192

Target Family

Non-IDG 143 | 12,091
Enzyme 21 | 4,145
Kinase 11 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Microtubule organizing center ... 177 | 177
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 295 kDa CEP295 Tdark Non-IDG -0.40512 3.13 13
Fidgetin FIGN Tbio Enzyme -1.34015 21.2 103
Centrosomal protein of 83 kDa CEP83 Tdark Non-IDG -0.47180 2.89 0
Poly [ADP-ribose] polymerase 3 PARP3 Tclin Enzyme -1.66230 41.9 193
Testis-specific serine kinase substrate TSKS Tbio Enzyme -0.99386 9.94 98
Tubulin epsilon chain TUBE1 Tbio Non-IDG -2.57316 368.1 99
Cilia- and flagella-associated protein 20 CFAP20 Tbio Non-IDG -1.78803 43.9 88
A-kinase anchor protein 9 AKAP9 Tbio Enzyme -2.22554 169.7 142
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Protein chibby homolog 1 CBY1 Tbio Non-IDG -2.29880 197.7 79