Development Level

Tbio 113 | 10,625
Tdark 27 | 7,003
Tchem 18 | 1,890
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to t... 6 | 187
abnormal behavior 5 | 226
decreased bone mineral content 5 | 157
decreased lean body mass 5 | 195
decreased total body fat amoun... 5 | 186
hyperactivity 4 | 108
increased mean corpuscular hem... 4 | 93
increased or absent threshold ... 4 | 128
abnormal head morphology 3 | 10
decreased body length 3 | 108
decreased body weight 3 | 174
decreased circulating choleste... 3 | 85
preweaning lethality, incomple... 3 | 260
abnormal bone structure 2 | 131
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal embryo turning 2 | 15
abnormal humerus morphology 2 | 11
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 33
decreased circulating glucose ... 2 | 121
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
embryonic growth retardation 2 | 28
hypoactivity 2 | 89
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal brain morphology 1 | 6
abnormal craniofacial morpholo... 1 | 12
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 20
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal tail morphology 1 | 17
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased basophil cell number 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating fructosa... 1 | 31
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lactate dehydrogenas... 1 | 14
decreased lumbar vertebrae num... 1 | 62
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
edema 1 | 11
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
hydroencephaly 1 | 6
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased CD8-positive, naive ... 1 | 3
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glycerol... 1 | 11
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
pale liver 1 | 5
polydactyly 1 | 22
prenatal lethality 1 | 16
short tibia 1 | 82
vertebral fusion 1 | 23

Disease

ovarian cancer 87 | 8,492
osteosarcoma 81 | 7,933
psoriasis 55 | 6,685
medulloblastoma, large-cell 54 | 6,234
glioblastoma 46 | 5,572
lung cancer 39 | 4,473
malignant mesothelioma 37 | 3,163
atypical teratoid / rhabdoid tumor 35 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
primitive neuroectodermal tumor 34 | 3,031
group 3 medulloblastoma 33 | 2,254
Carcinoma 32 | 2,147
posterior fossa group B ependymoma 31 | 1,530
Breast cancer 29 | 3,099
pediatric high grade glioma 29 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
adrenocortical carcinoma 25 | 1,427
ependymoma 24 | 2,514
non-small cell lung cancer 24 | 2,798
pilocytic astrocytoma 23 | 3,086
Cancer 22 | 2,346
Pick disease 22 | 1,893
oligodendroglioma 22 | 2,849
invasive ductal carcinoma 21 | 2,950
colon cancer 20 | 1,475
group 4 medulloblastoma 19 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
Intellectual disability 18 | 573
astrocytic glioma 18 | 2,241
lung adenocarcinoma 18 | 2,714
nasopharyngeal carcinoma 18 | 1,056
pancreatic cancer 18 | 2,300
Microcephaly 17 | 149
ductal carcinoma in situ 17 | 1,745
sonic hedgehog group medulloblastoma 17 | 1,482
ulcerative colitis 17 | 2,087
Atopic dermatitis 15 | 944
lung carcinoma 15 | 2,844
Joubert syndrome 13 | 62
breast carcinoma 13 | 1,614
posterior fossa group A ependymoma 13 | 1,511
subependymal giant cell astrocytoma 13 | 2,287
tuberculosis 13 | 1,563
Ciliopathy 12 | 57
Polydactyly 12 | 93
adult high grade glioma 12 | 2,148
interstitial cystitis 12 | 2,299
progressive supranuclear palsy 12 | 674
Nephronophthisis 11 | 74
astrocytoma 11 | 1,493
tuberculosis and treatment for 6 months 11 | 686
Endometriosis 10 | 535
chronic rhinosinusitis 10 | 512
non primary Sjogren syndrome sicca 10 | 840
Rheumatoid Arthritis 9 | 1,171
atypical teratoid/rhabdoid tumor 9 | 1,095
medulloblastoma 9 | 1,524
pituitary cancer 9 | 1,972
Bardet-Biedl Syndrome 8 | 40
Obesity 8 | 616
Seckel syndrome 8 | 35
diabetes mellitus 8 | 1,663
primary Sjogren syndrome 8 | 789
Asphyxiating thoracic dystrophy 7 | 34
Cystic kidney disease 7 | 26
Meckel syndrome 7 | 48
active Crohn's disease 7 | 918
Amyotrophic Lateral Sclerosis 6 | 432
IGA Glomerulonephritis 6 | 454
Neurodegenerative disease 6 | 383
Orofaciodigital syndrome 6 | 19
Paraplegia 6 | 71
Prostate cancer 6 | 172
Retinitis pigmentosa 6 | 156
Schizophrenia 6 | 503
Senior-Loken syndrome 6 | 22
gastric cancer 6 | 436
pancreatic carcinoma 6 | 567
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primary pancreatic ductal adenocarcinoma 6 | 1,271
Parkinson's disease 5 | 364
Polycystic kidney disease 5 | 54
acute quadriplegic myopathy 5 | 1,157
aldosterone-producing adenoma 5 | 664
dermatomyositis 5 | 967
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 550
spina bifida 5 | 1,064
Bardet-Biedl syndrome 1 4 | 22
Hydrolethalus syndrome 4 | 128
Leber congenital amaurosis 4 | 72
Mammary Neoplasms 4 | 410
Mammary Neoplasms, Experimental 4 | 150
Peripheral Neuropathy 4 | 303
Primary ciliary dyskinesia 4 | 75
Prostatic Neoplasms 4 | 471
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 477
acute myeloid leukemia 4 | 785
inflammatory breast cancer 4 | 404

Tissue

Male tissues 155 | 17,969
Blood and immune system 154 | 17,995
Cardiovascular System 154 | 17,958
Digestive Tract 154 | 18,473
Endocrine System 154 | 18,512
Female tissues 154 | 18,647
Liver and Pancreas 154 | 18,136
Nervous System 154 | 18,561
Respiratory system 153 | 17,484
Urinary Tract 153 | 18,444
Skin and soft tissues 152 | 18,115

Target Family

Non-IDG 128 | 11,969
Enzyme 19 | 4,146
Kinase 12 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Microtubule organizing center ... 161 | 161
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Hook homolog 3 HOOK3 Tbio Non-IDG -1.18684 0.00000 55
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.03835 107.4 139
Testis-specific serine/threonine-protein kinase 2 TSSK2 Tbio Kinase -1.03021 11.5 47
Gamma-tubulin complex component 2 TUBGCP2 Tdark Non-IDG -0.77055 4.80 96
WAS protein family homolog 1 WASHC1 Tbio Non-IDG -0.16688 1.80 3
Macrophage-capping protein CAPG Tbio Non-IDG -1.29740 22.4 235
Centrosomal protein of 120 kDa CEP120 Tbio Non-IDG -0.80256 7.31 42
Sodium channel and clathrin linker 1 SCLT1 Tdark Non-IDG -0.39314 1.23 79
Centromere protein J CENPJ Tbio Non-IDG -1.78980 57.1 86
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.06059 1176.3 707