Development Level

Tbio 425 | 10,625
Tdark 109 | 7,003
Tchem 70 | 1,890
Tclin 13 | 602

Collection

Eligible Kinase Proteins 10 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 37 | 633
decreased lean body mass 12 | 195
decreased bone mineral content 10 | 157
decreased total body fat amoun... 10 | 186
embryonic lethality prior to t... 10 | 187
decreased body weight 9 | 174
abnormal behavior 8 | 226
increased or absent threshold ... 8 | 128
preweaning lethality, incomple... 8 | 260
decreased bone mineral density 7 | 126
increased mean corpuscular hem... 7 | 93
hyperactivity 6 | 108
hypoactivity 6 | 89
increased circulating alkaline... 6 | 119
increased leukocyte cell numbe... 6 | 37
abnormal embryo size 5 | 112
decreased body length 5 | 108
embryonic lethality prior to o... 5 | 148
increased circulating choleste... 5 | 53
increased grip strength 5 | 83
increased mean corpuscular vol... 5 | 91
increased total body fat amoun... 5 | 57
prenatal lethality prior to he... 5 | 64
abnormal bone structure 4 | 131
abnormal head morphology 4 | 10
abnormal lens morphology 4 | 73
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased circulating serum al... 4 | 79
decreased grip strength 4 | 123
decreased lumbar vertebrae num... 4 | 62
improved glucose tolerance 4 | 56
increased circulating HDL chol... 4 | 63
increased circulating iron lev... 4 | 25
increased exploration in new e... 4 | 56
increased fasted circulating g... 4 | 68
increased lean body mass 4 | 107
increased sacral vertebrae num... 4 | 62
abnormal kidney morphology 3 | 30
abnormal limb bud morphology 3 | 15
abnormal spleen morphology 3 | 36
abnormal tail morphology 3 | 17
decreased basophil cell number 3 | 11
hydrops fetalis 3 | 22
impaired glucose tolerance 3 | 52
increased body weight 3 | 42
increased bone mineral content 3 | 92
increased bone mineral density 3 | 52
increased circulating glucose ... 3 | 16
increased hematocrit 3 | 36
short tibia 3 | 82
abnormal bone mineralization 2 | 55
abnormal coat/ hair morphology 2 | 18
abnormal cranium morphology 2 | 32
abnormal embryo turning 2 | 15
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 14
abnormal neural tube closure 2 | 37
abnormal response to tactile s... 2 | 16
abnormal retina morphology 2 | 100
abnormal startle reflex 2 | 14
abnormal tail movements 2 | 12
abnormal testis morphology 2 | 30
cardiovascular system phenotyp... 2 | 35
cataract 2 | 26
decreased blood urea nitrogen ... 2 | 31
decreased circulating HDL chol... 2 | 77
decreased circulating bilirubi... 2 | 14
decreased circulating calcium ... 2 | 33
decreased circulating total pr... 2 | 41
decreased hematocrit 2 | 25
decreased leukocyte cell numbe... 2 | 54
edema 2 | 11
embryonic growth retardation 2 | 28
hemorrhage 2 | 12
immune system phenotype 2 | 17
increased NK cell number 2 | 19
increased circulating LDL chol... 2 | 15
increased circulating serum al... 2 | 25
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased startle reflex 2 | 38
male infertility 2 | 62
small testis 2 | 37
vertebral fusion 2 | 23
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
absent pinna reflex 1 | 21
corneal opacity 1 | 25
decreased circulating chloride... 1 | 32
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
increased rib number 1 | 41
limb grasping 1 | 35
prenatal lethality 1 | 16

Disease

ovarian cancer 359 | 8,484
osteosarcoma 316 | 7,933
medulloblastoma, large-cell 260 | 6,234
psoriasis 233 | 6,685
glioblastoma 229 | 5,572
atypical teratoid / rhabdoid tumor 188 | 4,369
lung cancer 182 | 4,466
primitive neuroectodermal tumor 155 | 3,031
Breast cancer 145 | 3,094
malignant mesothelioma 145 | 3,162
group 3 medulloblastoma 125 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 121 | 3,289
pediatric high grade glioma 121 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 114 | 2,988
oligodendroglioma 114 | 2,849
non-small cell lung cancer 109 | 2,798
invasive ductal carcinoma 106 | 2,950
Pick disease 103 | 1,893
Carcinoma 102 | 2,147
posterior fossa group B ependymoma 100 | 1,530
ependymoma 98 | 2,514
Cancer 93 | 2,346
lung adenocarcinoma 92 | 2,713
pilocytic astrocytoma 84 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 83 | 2,956
astrocytic glioma 82 | 2,241
adrenocortical carcinoma 77 | 1,427
pancreatic cancer 77 | 2,300
subependymal giant cell astrocytoma 75 | 2,287
adult high grade glioma 72 | 2,148
colon cancer 71 | 1,475
lung carcinoma 69 | 2,844
ductal carcinoma in situ 68 | 1,745
group 4 medulloblastoma 68 | 1,875
breast carcinoma 64 | 1,614
sonic hedgehog group medulloblastoma 62 | 1,482
posterior fossa group A ependymoma 61 | 1,511
astrocytoma 60 | 1,493
medulloblastoma 59 | 1,524
ulcerative colitis 58 | 2,087
atypical teratoid/rhabdoid tumor 57 | 1,095
nasopharyngeal carcinoma 57 | 1,056
pituitary cancer 53 | 1,972
Multiple myeloma 52 | 1,327
Intellectual disability 51 | 573
interstitial cystitis 50 | 2,299
tuberculosis 50 | 1,557
diabetes mellitus 49 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,795
acute quadriplegic myopathy 48 | 1,157
Rheumatoid Arthritis 44 | 1,160
Atopic dermatitis 40 | 944
chronic rhinosinusitis 39 | 512
dermatomyositis 38 | 933
juvenile dermatomyositis 38 | 1,189
progressive supranuclear palsy 38 | 674
tuberculosis and treatment for 6 months 38 | 686
Endometriosis 37 | 535
primary pancreatic ductal adenocarcinoma 36 | 1,271
Waldenstrons macroglobulinemia 35 | 765
spina bifida 35 | 1,064
Microcephaly 34 | 149
non primary Sjogren syndrome sicca 33 | 840
IGA Glomerulonephritis 32 | 454
Ciliopathy 31 | 57
active Crohn's disease 31 | 918
Obesity 29 | 616
Polydactyly 29 | 93
cystic fibrosis 28 | 1,665
Amyotrophic Lateral Sclerosis 27 | 431
Neurodegenerative disease 26 | 383
Joubert syndrome 25 | 61
Nephronophthisis 25 | 74
acute myeloid leukemia 25 | 780
Retinitis pigmentosa 24 | 153
pancreatic carcinoma 24 | 567
aldosterone-producing adenoma 23 | 664
cutaneous lupus erythematosus 23 | 1,056
hepatocellular carcinoma 23 | 532
primary Sjogren syndrome 23 | 789
Bardet-Biedl Syndrome 22 | 40
esophageal adenocarcinoma 22 | 737
gastric cancer 22 | 430
Mammary Neoplasms 21 | 410
Prostatic Neoplasms 21 | 471
hereditary spastic paraplegia 21 | 313
Alzheimer's disease 19 | 644
Down syndrome 19 | 548
Schizophrenia 19 | 501
gastric carcinoma 19 | 832
Asphyxiating thoracic dystrophy 18 | 32
Meckel syndrome 17 | 48
Parkinson's disease 17 | 364
fibroadenoma 17 | 557
non-small cell lung carcinoma 17 | 413
active ulcerative colitis 16 | 477
cystic fibrosis and chronic rhinosinusitis 16 | 213
Fundus dystrophy 15 | 77
Crohn's disease 13 | 304
Duchenne muscular dystrophy 13 | 602

Tissue

Blood and immune system 608 | 17,995
Endocrine System 608 | 18,512
Digestive Tract 607 | 18,473
Female tissues 607 | 18,647
Liver and Pancreas 607 | 18,136
Nervous System 607 | 18,561
Cardiovascular System 606 | 17,958
Male tissues 606 | 17,969
Urinary Tract 606 | 18,444
Skin and soft tissues 603 | 18,115
Respiratory system 601 | 17,484

Target Family

Non-IDG 435 | 11,971
Enzyme 99 | 4,146
Kinase 53 | 634
Transcription Factor 14 | 1,400
Epigenetic 7 | 242
Transporter 5 | 473
Ion Channel 3 | 341
Nuclear Receptor 1 | 48

Compartment GO Term

Microtubule organizing center 617 | 617
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Coiled-coil domain-containing protein 15 CCDC15 Tdark Non-IDG 0.00000 53
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
Ankyrin repeat domain-containing protein 26 ANKRD26 Tbio Non-IDG -1.28843 22.9 87
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.72231 55.8 158
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84