Development Level

Tbio 114 | 10,625
Tchem 26 | 1,890
Tdark 26 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 20 | 633
increased or absent threshold ... 4 | 128
preweaning lethality, incomple... 4 | 260
abnormal embryo size 3 | 112
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
abnormal behavior 2 | 226
abnormal sleep behavior 2 | 63
decreased bone mineral content 2 | 157
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased red blood cell distr... 2 | 11
decreased startle reflex 2 | 48
hyperactivity 2 | 108
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased mean corpuscular hem... 2 | 93
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal lens morphology 1 | 73
abnormal limb morphology 1 | 7
abnormal outer ear morphology 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
absent pinna reflex 1 | 21
cyanosis 1 | 6
decreased B cell number 1 | 30
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased effector memory CD4-... 1 | 6
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
hemorrhage 1 | 12
impaired glucose tolerance 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 25
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality 1 | 16

Disease

ovarian cancer 88 | 8,492
osteosarcoma 78 | 7,933
medulloblastoma, large-cell 75 | 6,234
psoriasis 70 | 6,685
glioblastoma 67 | 5,572
atypical teratoid / rhabdoid tumor 59 | 4,369
lung cancer 55 | 4,473
pediatric high grade glioma 47 | 2,712
primitive neuroectodermal tumor 44 | 3,031
Carcinoma 42 | 2,147
group 3 medulloblastoma 42 | 2,254
Breast cancer 39 | 3,099
oligodendroglioma 38 | 2,849
malignant mesothelioma 37 | 3,163
non-small cell lung cancer 37 | 2,798
posterior fossa group B ependymoma 37 | 1,530
invasive ductal carcinoma 35 | 2,950
lung adenocarcinoma 35 | 2,714
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
nasopharyngeal carcinoma 30 | 1,056
pilocytic astrocytoma 30 | 3,086
adrenocortical carcinoma 29 | 1,427
Pick disease 27 | 1,893
lung carcinoma 26 | 2,844
colon cancer 25 | 1,475
breast carcinoma 24 | 1,614
ductal carcinoma in situ 24 | 1,745
ependymoma 23 | 2,514
Atopic dermatitis 21 | 944
pancreatic cancer 20 | 2,300
posterior fossa group A ependymoma 20 | 1,511
Cancer 19 | 2,346
astrocytoma 19 | 1,493
Endometriosis 18 | 535
Multiple myeloma 18 | 1,328
Primary ciliary dyskinesia 18 | 75
adult high grade glioma 18 | 2,148
astrocytic glioma 18 | 2,241
group 4 medulloblastoma 18 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
Situs Inversus 17 | 52
chronic rhinosinusitis 17 | 512
pituitary cancer 17 | 1,972
subependymal giant cell astrocytoma 17 | 2,287
sonic hedgehog group medulloblastoma 15 | 1,482
ulcerative colitis 15 | 2,087
IGA Glomerulonephritis 14 | 454
Neurodegenerative disease 14 | 383
acute myeloid leukemia 13 | 785
atypical teratoid/rhabdoid tumor 13 | 1,095
interstitial cystitis 13 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Alzheimer's disease 11 | 644
Kartagener Syndrome 11 | 32
diabetes mellitus 11 | 1,663
progressive supranuclear palsy 11 | 674
Microcephaly 10 | 149
juvenile dermatomyositis 10 | 1,189
medulloblastoma 10 | 1,524
spina bifida 10 | 1,064
Intellectual disability 9 | 573
Lissencephaly 9 | 61
acute quadriplegic myopathy 9 | 1,157
cutaneous lupus erythematosus 9 | 1,056
dermatomyositis 9 | 967
inflammatory breast cancer 9 | 404
tuberculosis 9 | 1,563
Ciliary Dyskinesia, Primary, 1 8 | 27
Kidney cancer 8 | 121
Male infertility 8 | 170
Neuropathy 8 | 210
Paraplegia 8 | 71
cystic fibrosis 8 | 1,670
gastric carcinoma 8 | 832
non-small cell lung carcinoma 8 | 413
Rheumatoid Arthritis 7 | 1,171
esophageal adenocarcinoma 7 | 737
hereditary spastic paraplegia 7 | 313
primary Sjogren syndrome 7 | 789
primary pancreatic ductal adenocarcinoma 7 | 1,271
Amyotrophic Lateral Sclerosis 6 | 432
Polydactyly 6 | 93
fibroadenoma 6 | 557
tuberculosis and treatment for 6 months 6 | 686
Asphyxiating thoracic dystrophy 5 | 34
Bronchiectasis 5 | 29
Cerebrovascular disease 5 | 231
Melanoma 5 | 261
Parkinson's disease 5 | 364
Waldenstrons macroglobulinemia 5 | 765
cystic fibrosis and chronic rhinosinusitis 5 | 213
Brain Ischemia 4 | 87
Down syndrome 4 | 548
Duchenne muscular dystrophy 4 | 602
Obesity 4 | 616
Schizophrenia 4 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
periodontitis 4 | 269
tuberculosis and treatment for 3 months 4 | 327

Tissue

Blood and immune system 167 | 17,995
Digestive Tract 167 | 18,473
Endocrine System 167 | 18,512
Female tissues 166 | 18,647
Nervous System 166 | 18,561
Skin and soft tissues 166 | 18,115
Cardiovascular System 165 | 17,958
Liver and Pancreas 165 | 18,136
Male tissues 165 | 17,969
Urinary Tract 165 | 18,444
Respiratory system 163 | 17,484

Target Family

Non-IDG 149 | 11,969
Enzyme 10 | 4,146
Kinase 7 | 634
Epigenetic 1 | 242

Compartment GO Term

Microtubule associated complex 167 | 167
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rab GTPase-activating protein 1 RABGAP1 Tbio Enzyme -0.67656 3.42 165
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.03835 107.4 139
Protein kintoun DNAAF2 Tbio Non-IDG -1.27669 17.1 22
Kinesin heavy chain isoform 5A KIF5A Tbio Non-IDG -1.65000 51.6 163
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.06059 1176.3 707
Cytoplasmic dynein 1 intermediate chain 2 DYNC1I2 Tbio Non-IDG -2.25048 162.2 87
Paxillin PXN Tchem Non-IDG -2.97313 849.9 1088
Echinoderm microtubule-associated protein-like 2 EML2 Tbio Non-IDG -0.54935 3.11 85
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.11321 131.9 241
Dynein intermediate chain 1, axonemal DNAI1 Tbio Non-IDG -1.85228 67.9 126