Development Level

Tbio 29 | 11,178

IMPC Phenotype

decreased body length 2 | 101
abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 23 | 11,192
psoriasis 22 | 6,514
ependymoma 18 | 4,559
pancreatic cancer 18 | 2,322
glioblastoma 17 | 5,635
invasive ductal carcinoma 17 | 2,867
ovarian cancer 17 | 8,297
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,872
primary pancreatic ductal adenocarcinoma 16 | 1,071
Astrocytoma, Pilocytic 15 | 3,006
Breast cancer 15 | 3,469
atypical teratoid / rhabdoid tumor 15 | 4,971
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,902
lung carcinoma 15 | 2,755
malignant mesothelioma 14 | 3,135
medulloblastoma, large-cell 14 | 6,086
Duchenne muscular dystrophy 13 | 587
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,204
osteosarcoma 13 | 7,766
adult high grade glioma 12 | 3,701
lung adenocarcinoma 12 | 2,627
non-small cell lung cancer 12 | 2,799
lung cancer 11 | 4,607
pituitary cancer 11 | 1,915
Autosomal recessive predisposition 10 | 1,407
Kidney cancer 10 | 2,548
ductal carcinoma in situ 10 | 1,686
limb girdle muscular dystrophy 2A 10 | 208
ulcerative colitis 10 | 1,765
Atopic dermatitis 9 | 915
Joint stiffness 9 | 80
adrenocortical carcinoma 9 | 1,385
breast carcinoma 9 | 1,589
Weill-Marchesani syndrome 8 | 14
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 492
colon cancer 8 | 1,428
gastric carcinoma 8 | 781
group 3 medulloblastoma 8 | 4,002
interstitial cystitis 8 | 2,237
juvenile dermatomyositis 8 | 1,147
primitive neuroectodermal tumor 8 | 2,957
Liver Cirrhosis, Experimental 7 | 733
Aortic aneurysm 6 | 33
Becker muscular dystrophy 6 | 184
Byzanthine arch palate 6 | 194
Cancer 6 | 2,388
Contracture 6 | 95
Cutis Laxa 6 | 39
Glaucoma 6 | 232
Joint laxity 6 | 52
Myopia 6 | 175
cystic fibrosis 6 | 1,629
diabetes mellitus 6 | 1,683
fascioscapulohumeral muscular dystrophy 6 | 98
medulloblastoma 6 | 702
Acquired metabolic disease 5 | 329
Acquired scoliosis 5 | 274
Contracture of joint 5 | 92
Curvature of spine 5 | 275
Down syndrome 5 | 480
Flexion contracture 5 | 92
Flexion contracture of proximal interphalangeal joint 5 | 74
Flexion contractures of joints 5 | 92
Generalized elastolysis 5 | 24
Hanging skin 5 | 24
Melanoma 5 | 689
Motor delay 5 | 144
No development of motor milestones 5 | 144
Orbital separation excessive 5 | 240
Pectus excavatum 5 | 100
Pulmonary emphysema 5 | 44
Round face 5 | 43
Round, full face 5 | 43
Short stature 5 | 514
Skin cancer 5 | 451
aldosterone-producing adenoma 5 | 646
cutaneous lupus erythematosus 5 | 1,016
interstitial lung disease 5 | 287
Aortic Valve Insufficiency 4 | 39
Arachnodactyly 4 | 49
Atherosclerosis 4 | 276
Bladder Diverticulum 4 | 15
Brachydactyly 4 | 154
Creatine phosphokinase serum increased 4 | 110
Elevated creatine kinase 4 | 110
Endometriosis 4 | 521
Hernia, Inguinal 4 | 88
Large intestine cancer 4 | 123
Liver cancer 4 | 589
Long philtrum 4 | 137
Mitral valve insufficiency 4 | 48
Polycystic ovary syndrome 4 | 348
Prominent ear 4 | 55
Prostatic Neoplasms 4 | 472
Protruding ears 4 | 55
astrocytic glioma 4 | 2,530
oligodendroglioma 4 | 2,768
pterygium 4 | 71
subependymal giant cell astrocytoma 4 | 2,230
tuberculosis 4 | 1,963

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Liver and Pancreas 28 | 16,750

Target Family

Non-IDG 25 | 12,091
Enzyme 4 | 4,145

Compartment GO Term

Microfibril 29 | 29
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Microfibrillar-associated protein 2 MFAP2 Tbio Non-IDG -1.84472 72.8 129
A disintegrin and metalloproteinase with thrombospondin motifs 17 ADAMTS17 Tbio Enzyme -0.75238 5.23 49
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57
Fibulin-5 FBLN5 Tbio Non-IDG -2.32385 217.1 297
ADAMTS-like protein 2 ADAMTSL2 Tbio Non-IDG -0.99914 9.30 69
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.79687 61.3 32
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204