Development Level

Tbio 29 | 11,651

IMPC Phenotype

decreased body length 2 | 101
abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 23 | 11,493
psoriasis 22 | 6,694
ependymoma 18 | 4,679
pancreatic cancer 18 | 2,398
glioblastoma 17 | 5,792
invasive ductal carcinoma 17 | 2,951
ovarian cancer 17 | 8,520
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
primary pancreatic ductal adenocarcinoma 16 | 1,109
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung carcinoma 15 | 2,843
malignant mesothelioma 14 | 3,232
medulloblastoma, large-cell 14 | 6,241
Duchenne muscular dystrophy 13 | 601
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
osteosarcoma 13 | 7,950
adult high grade glioma 12 | 3,801
lung adenocarcinoma 12 | 2,716
non-small cell lung cancer 12 | 2,890
lung cancer 11 | 4,740
pituitary cancer 11 | 1,972
Autosomal recessive predisposition 10 | 1,442
Kidney cancer 10 | 2,613
ductal carcinoma in situ 10 | 1,745
limb girdle muscular dystrophy 2A 10 | 213
ulcerative colitis 10 | 1,819
Atopic dermatitis 9 | 952
Joint stiffness 9 | 84
adrenocortical carcinoma 9 | 1,428
breast carcinoma 9 | 1,638
Weill-Marchesani syndrome 8 | 14
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
colon cancer 8 | 1,478
gastric carcinoma 8 | 807
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
juvenile dermatomyositis 8 | 1,187
primitive neuroectodermal tumor 8 | 3,035
Liver Cirrhosis, Experimental 7 | 769
Aortic aneurysm 6 | 38
Becker muscular dystrophy 6 | 191
Byzanthine arch palate 6 | 194
Cancer 6 | 2,499
Contracture 6 | 96
Cutis Laxa 6 | 39
Glaucoma 6 | 239
Joint laxity 6 | 54
Myopia 6 | 176
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
fascioscapulohumeral muscular dystrophy 6 | 100
medulloblastoma 6 | 720
Acquired metabolic disease 5 | 336
Acquired scoliosis 5 | 281
Contracture of joint 5 | 93
Curvature of spine 5 | 282
Down syndrome 5 | 499
Flexion contracture 5 | 93
Flexion contracture of proximal interphalangeal joint 5 | 75
Flexion contractures of joints 5 | 93
Generalized elastolysis 5 | 24
Hanging skin 5 | 24
Melanoma 5 | 711
Motor delay 5 | 147
No development of motor milestones 5 | 147
Orbital separation excessive 5 | 244
Pectus excavatum 5 | 100
Pulmonary emphysema 5 | 48
Round face 5 | 45
Round, full face 5 | 45
Short stature 5 | 531
Skin cancer 5 | 469
aldosterone-producing adenoma 5 | 665
cutaneous lupus erythematosus 5 | 1,057
interstitial lung disease 5 | 298
Aortic Valve Insufficiency 4 | 40
Arachnodactyly 4 | 49
Atherosclerosis 4 | 291
Bladder Diverticulum 4 | 15
Brachydactyly 4 | 156
Creatine phosphokinase serum increased 4 | 110
Elevated creatine kinase 4 | 110
Endometriosis 4 | 540
Hernia, Inguinal 4 | 89
Large intestine cancer 4 | 126
Liver cancer 4 | 604
Long philtrum 4 | 137
Mitral valve insufficiency 4 | 49
Polycystic ovary syndrome 4 | 360
Prominent ear 4 | 56
Prostatic Neoplasms 4 | 495
Protruding ears 4 | 56
astrocytic glioma 4 | 2,597
oligodendroglioma 4 | 2,850
pterygium 4 | 76
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Liver and Pancreas 28 | 16,750

Target Family

Non-IDG 25 | 12,091
Enzyme 4 | 4,145

Compartment GO Term

Microfibril 29 | 29
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Fibulin-2 FBLN2 Tbio Non-IDG -1.72650 54.6 170
EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 Tbio Non-IDG -2.17305 162.6 259
Decorin DCN Tbio Non-IDG -3.05208 1155.4 480
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Fibulin-1 FBLN1 Tbio Non-IDG -1.97380 101.1 218
Fibrillin-3 FBN3 Tbio Non-IDG -1.23024 15.7 16
A disintegrin and metalloproteinase with thrombospondin motifs 10 ADAMTS10 Tbio Enzyme -1.35665 21.7 120
Fibrillin-2 FBN2 Tbio Non-IDG -2.46578 287.6 123