Development Level

Tbio 70 | 10,625
Tchem 14 | 1,890
Tdark 9 | 7,003
Tclin 3 | 602

IMPC Term

decreased body weight 5 | 174
decreased total body fat amoun... 4 | 186
decreased circulating choleste... 3 | 85
decreased threshold for audito... 3 | 32
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
abnormal heart morphology 2 | 51
abnormal sleep behavior 2 | 63
abnormal tail morphology 2 | 17
abnormal tibia morphology 2 | 14
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased circulating lipase l... 2 | 2
decreased heart weight 2 | 44
decreased lean body mass 2 | 195
enlarged heart 2 | 111
increased or absent threshold ... 2 | 128
abnormal body size 1 | 1
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 3
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 8
abnormal response to tactile s... 1 | 16
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased Ly6C high monocyte n... 1 | 12
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 43
increased circulating fructosa... 1 | 11
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased heart rate 1 | 17
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
shortened RR interval 1 | 19
thick tail 1 | 1
thrombocytopenia 1 | 46

Disease

ovarian cancer 54 | 8,484
psoriasis 45 | 6,685
osteosarcoma 40 | 7,933
medulloblastoma, large-cell 37 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,795
Zellweger Syndrome 30 | 38
glioblastoma 29 | 5,572
atypical teratoid / rhabdoid tumor 27 | 4,369
lung cancer 25 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
malignant mesothelioma 21 | 3,162
ependymoma 20 | 2,514
ulcerative colitis 20 | 2,087
Adrenoleukodystrophy 19 | 31
Peroxisomal disease 19 | 20
Chondrodysplasia punctata 18 | 41
invasive ductal carcinoma 18 | 2,950
Infantile refsum disease 17 | 19
interstitial cystitis 17 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
oligodendroglioma 16 | 2,849
pediatric high grade glioma 15 | 2,712
astrocytic glioma 14 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
Adrenoleukodystrophy, Neonatal 13 | 13
Infantile Refsum Disease (disorder) 13 | 13
Pick disease 13 | 1,893
primitive neuroectodermal tumor 13 | 3,031
Atopic dermatitis 12 | 944
Refsum disease 12 | 21
ductal carcinoma in situ 12 | 1,745
pilocytic astrocytoma 12 | 3,086
pituitary cancer 12 | 1,972
Breast cancer 11 | 3,094
Peroxisome biogenesis disorders 11 | 11
astrocytoma 11 | 1,493
diabetes mellitus 11 | 1,663
lung carcinoma 11 | 2,844
pancreatic cancer 11 | 2,300
Multiple myeloma 10 | 1,327
posterior fossa group B ependymoma 10 | 1,530
subependymal giant cell astrocytoma 10 | 2,287
tuberculosis 10 | 1,557
Rhizomelic chondrodysplasia punctata 9 | 11
acute quadriplegic myopathy 9 | 1,157
lung adenocarcinoma 9 | 2,713
non-small cell lung cancer 9 | 2,798
Waldenstrons macroglobulinemia 8 | 765
adult high grade glioma 8 | 2,148
colon cancer 8 | 1,475
group 4 medulloblastoma 8 | 1,875
medulloblastoma 7 | 1,524
Cataract 6 | 104
Intellectual disability 6 | 573
Obesity 6 | 616
active Crohn's disease 6 | 918
acute myeloid leukemia 6 | 780
aldosterone-producing adenoma 6 | 664
cystic fibrosis 6 | 1,665
group 3 medulloblastoma 6 | 2,254
nephrosclerosis 6 | 329
posterior fossa group A ependymoma 6 | 1,511
primary pancreatic ductal adenocarcinoma 6 | 1,271
progressive supranuclear palsy 6 | 674
sonic hedgehog group medulloblastoma 6 | 1,482
spina bifida 6 | 1,064
Cancer 5 | 2,346
Carcinoma 5 | 2,147
Kidney disease 5 | 396
PEROXISOME BIOGENESIS DISORDER 2B 5 | 5
Rheumatoid Arthritis 5 | 1,160
cutaneous lupus erythematosus 5 | 1,056
juvenile dermatomyositis 5 | 1,189
pancreatic carcinoma 5 | 567
Alzheimer's disease 4 | 644
Colorectal Neoplasms 4 | 217
Down syndrome 4 | 548
Fatty liver disease 4 | 84
IGA Glomerulonephritis 4 | 454
Liver carcinoma 4 | 217
Peroxisomal acyl-CoA oxidase deficiency 4 | 4
Primary hyperoxaluria 4 | 15
Prostatic Neoplasms 4 | 471
adrenocortical carcinoma 4 | 1,427
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
gastric cancer 4 | 430
gastric carcinoma 4 | 832
hereditary spastic paraplegia 4 | 313
non primary Sjogren syndrome sicca 4 | 840
tuberculosis and treatment for 6 months 4 | 686
Cerebrovascular disease 3 | 231
Hypertension 3 | 287
Nephrocalcinosis 3 | 18
Polycystic Ovary Syndrome 3 | 332
Schizophrenia 3 | 501
glioblastoma multiforme 3 | 347
hepatocellular carcinoma 3 | 532
nasopharyngeal carcinoma 3 | 1,056
non diabetic and post-ischemic heart failure 3 | 200

Tissue

Blood and immune system 96 | 17,995
Cardiovascular System 96 | 17,958
Digestive Tract 96 | 18,473
Endocrine System 96 | 18,512
Female tissues 96 | 18,647
Liver and Pancreas 96 | 18,136
Male tissues 96 | 17,969
Nervous System 96 | 18,561
Urinary Tract 96 | 18,444
Respiratory system 95 | 17,484
Skin and soft tissues 95 | 18,115

Target Family

Enzyme 55 | 4,146
Non-IDG 34 | 11,971
Transporter 6 | 473
Kinase 1 | 634

Compartment GO Term

Microbody part 96 | 96
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal multifunctional enzyme type 2 HSD17B4 Tbio Non-IDG -2.15826 152.2 203
Peroxisomal leader peptide-processing protease TYSND1 Tbio Enzyme -0.49732 3.53 45
Insulin-degrading enzyme IDE Tchem Enzyme -2.54789 384.2 283
Peroxisomal membrane protein 11A PEX11A Tbio Non-IDG -1.69751 54.6 104
Putative acyl-coenzyme A thioesterase 6 ACOT6 Tdark Enzyme 0.43 0.54 14
Peroxisomal acyl-coenzyme A oxidase 3 ACOX3 Tdark Enzyme -1.21608 14.6 47
Peroxisomal membrane protein PMP34 SLC25A17 Tbio Transporter -2.13362 106.2 64
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.78634 57.0 688
Ubiquitin-conjugating enzyme E2 D2 UBE2D2 Tbio Non-IDG -2.06903 107.6 211
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.69037 4.43 94