Development Level

Tbio 71 | 11,445
Tchem 10 | 1,598
Tdark 8 | 6,588
Tclin 1 | 613

IMPC Phenotype

decreased body length 4 | 101
preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal tail morphology 2 | 25
abnormal tibia morphology 2 | 14
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hypoactivity 2 | 132
increased circulating bilirubi... 2 | 16
increased lean body mass 2 | 172
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
long tail 1 | 1
male infertility 1 | 123
mammalian phenotype 1 | 17
shortened RR interval 1 | 17
thick tail 1 | 1
thrombocytopenia 1 | 56

Disease

Carcinoma 58 | 11,493
ovarian cancer 49 | 8,520
psoriasis 43 | 6,694
osteosarcoma 36 | 7,950
medulloblastoma, large-cell 33 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,962
Zellweger syndrome 30 | 37
Autosomal recessive predisposition 29 | 1,442
glioblastoma 27 | 5,792
atypical teratoid / rhabdoid tumor 26 | 5,112
ependymoma 26 | 4,679
lung cancer 25 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Epilepsy 21 | 792
Infantile Refsum disease 21 | 23
Muscle hypotonia 21 | 571
Peroxisomal disease 21 | 22
Seizures 21 | 596
malignant mesothelioma 20 | 3,232
Cataract 19 | 297
Failure to gain weight 19 | 365
Pediatric failure to thrive 19 | 365
Short stature 19 | 531
Adrenoleukodystrophy 18 | 29
Chondrodysplasia punctata 18 | 41
Concave bridge of nose 18 | 195
Depressed nasal bridge 18 | 195
Depressed nasal root/bridge 18 | 195
Muscle Spasticity 18 | 195
Nystagmus 18 | 317
Sensorineural Hearing Loss (disorder) 18 | 284
invasive ductal carcinoma 18 | 2,951
Hepatomegaly 17 | 285
Low Vision 17 | 174
Retinitis Pigmentosa 17 | 226
Visual Impairment 17 | 174
adult high grade glioma 17 | 3,801
interstitial cystitis 17 | 2,312
Abnormal skeletal development 16 | 60
Abnormality of metabolism/homeostasis 16 | 134
Abnormality of retinal pigmentation 16 | 111
Cerebellar Ataxia 16 | 304
Cognitive delay 16 | 608
Developmental regression 16 | 95
Global developmental delay 16 | 608
Hypoplastic mandible condyle 16 | 275
Lens Opacities 16 | 231
Loss of developmental milestones 16 | 95
Mandibular hypoplasia 16 | 275
Mental and motor retardation 16 | 608
Mental deterioration in childhood 16 | 95
Micrognathism 16 | 275
Neurodevelopmental regression 16 | 95
Optic Atrophy 16 | 242
Osteochondrodysplasias 16 | 72
Psychomotor regression 16 | 95
Psychomotor regression beginning in infancy 16 | 95
Psychomotor regression in infants 16 | 95
Psychomotor regression, progressive 16 | 95
Retinal pigment epithelial abnormality 16 | 111
Small head 16 | 374
astrocytic glioma 16 | 2,597
Addison Disease 15 | 18
Adrenal cortical hypofunction 15 | 23
Anteverted nostril 15 | 191
Big calvaria 15 | 147
Blepharoptosis 15 | 231
Broad flat nasal bridge 15 | 236
Byzanthine arch palate 15 | 194
Congenital Epicanthus 15 | 177
Difficulties with night vision 15 | 87
Elevated levels of phytanic acid 15 | 15
High forehead 15 | 102
Increased head circumference 15 | 147
Increased size of cranium 15 | 147
Increased size of skull 15 | 147
Liver Failure 15 | 73
Nasal bridge wide 15 | 236
Night Blindness 15 | 101
Respiratory Insufficiency 15 | 132
Respiratory function loss 15 | 121
Stippled epiphyses 15 | 28
Strabismus 15 | 270
Tall forehead 15 | 102
Upward slant of palpebral fissure 15 | 75
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
oligodendroglioma 15 | 2,850
ulcerative colitis 15 | 1,819
Electroencephalogram abnormal 14 | 101
Feeding difficulties in infancy 14 | 175
Hyperreflexia 14 | 209
Icterus 14 | 82
Liver diseases 14 | 87
Long narrow head 14 | 75
Polymicrogyria 14 | 48
Premature Birth 14 | 77
ductal carcinoma in situ 14 | 1,745
primitive neuroectodermal tumor 14 | 3,035
tuberculosis 14 | 2,010

Tissue

Liver and Pancreas 89 | 16,750
Urinary Tract 89 | 16,678
Blood and immune system 88 | 16,909
Digestive Tract 88 | 17,369
Endocrine System 88 | 18,159
Skin and soft tissues 88 | 17,230
Female tissues 87 | 17,400
Nervous System 87 | 16,725
Male tissues 86 | 17,142
Respiratory system 86 | 16,393
Cardiovascular System 81 | 15,192

Target Family

Enzyme 51 | 4,145
Non-IDG 33 | 12,091
Transporter 6 | 473

Compartment GO Term

Microbody part 90 | 90
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Fatty acyl-CoA reductase 1 FAR1 Tbio Enzyme -1.65427 43.8 27
Nucleoside diphosphate-linked moiety X motif 19 NUDT19 Tdark Non-IDG 0.90 0.09 79
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Peroxisomal membrane protein 4 PXMP4 Tdark Non-IDG -0.51334 4.00 99
Peroxisome assembly factor 2 PEX6 Tbio Enzyme -1.89379 79.8 148
Lon protease homolog 2, peroxisomal LONP2 Tbio Enzyme -1.00177 8.20 100
Ketimine reductase mu-crystallin CRYM Tbio Enzyme -1.70644 52.5 199
ATP-binding cassette sub-family D member 3 ABCD3 Tbio Transporter -1.82051 64.2 166