Development Level

Tbio 126 | 11,445
Tchem 41 | 1,598
Tdark 15 | 6,588
Tclin 13 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 7 | 499
decreased body weight 6 | 161
decreased vertical activity 6 | 208
increased total body fat amoun... 6 | 134
decreased mean corpuscular vol... 5 | 79
abnormal heart morphology 4 | 162
abnormal lens morphology 4 | 81
cataract 4 | 92
decreased circulating choleste... 4 | 93
enlarged heart 4 | 210
increased circulating alkaline... 4 | 122
abnormal behavior 3 | 298
decreased circulating aspartat... 3 | 34
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased circulating bilirubi... 3 | 16
increased circulating choleste... 3 | 66
increased heart weight 3 | 62
increased red blood cell distr... 3 | 34
increased startle reflex 3 | 112
male infertility 3 | 123
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart left ventricle ... 2 | 16
abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
abnormal tibia morphology 2 | 14
abnormal vertebrae morphology 2 | 18
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating calcium ... 2 | 36
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
increased circulating amylase ... 2 | 25
increased circulating creatini... 2 | 38
increased circulating phosphat... 2 | 26
increased heart rate 2 | 23
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
small testis 2 | 58
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal neural tube closure 1 | 46
abnormal response to new envir... 1 | 10
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 128 | 11,493
ovarian cancer 109 | 8,520
psoriasis 92 | 6,694
osteosarcoma 82 | 7,950
medulloblastoma, large-cell 71 | 6,241
diabetes mellitus 68 | 1,728
Obesity 66 | 678
glioblastoma 63 | 5,792
lung cancer 58 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 55 | 1,962
atypical teratoid / rhabdoid tumor 53 | 5,112
invasive ductal carcinoma 53 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,291
malignant mesothelioma 48 | 3,232
Autosomal recessive predisposition 47 | 1,442
ependymoma 45 | 4,679
Cancer 43 | 2,499
ulcerative colitis 43 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,955
ductal carcinoma in situ 40 | 1,745
Fatty liver disease 39 | 103
tuberculosis 38 | 2,010
Schizophrenia 37 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
group 3 medulloblastoma 36 | 4,104
adult high grade glioma 35 | 3,801
lung carcinoma 35 | 2,843
interstitial cystitis 34 | 2,312
Lipid metabolism disorder 33 | 114
primitive neuroectodermal tumor 33 | 3,035
Atherosclerosis 32 | 291
Hepatomegaly 32 | 285
Seizures 32 | 596
lung adenocarcinoma 32 | 2,716
Breast cancer 31 | 3,578
Muscle hypotonia 31 | 571
Zellweger syndrome 31 | 37
Epilepsy 29 | 792
Hypertension 29 | 396
Hyperglycemia 28 | 137
Liver Cirrhosis, Experimental 28 | 769
non-small cell lung cancer 28 | 2,890
Astrocytoma, Pilocytic 27 | 3,081
astrocytic glioma 27 | 2,597
pituitary cancer 27 | 1,972
Atopic dermatitis 25 | 952
Pick disease 25 | 1,894
Short stature 25 | 531
astrocytoma 25 | 1,146
oligodendroglioma 25 | 2,850
Hypertensive disease 24 | 292
Kidney disease 24 | 430
adrenocortical carcinoma 24 | 1,428
pancreatic cancer 24 | 2,398
subependymal giant cell astrocytoma 24 | 2,287
Cataract 23 | 297
Failure to gain weight 23 | 365
Multiple myeloma 23 | 1,332
Pediatric failure to thrive 23 | 365
acute quadriplegic myopathy 23 | 1,158
breast carcinoma 23 | 1,638
Chemical and Drug Induced Liver Injury 22 | 195
Coronary artery disease 22 | 268
colon cancer 22 | 1,478
Alzheimer's disease 21 | 658
Concave bridge of nose 21 | 195
Depressed nasal bridge 21 | 195
Depressed nasal root/bridge 21 | 195
Infantile Refsum disease 21 | 23
Kidney cancer 21 | 2,613
Liver disease 21 | 237
Peroxisomal disease 21 | 22
cystic fibrosis 21 | 1,696
Cognitive delay 20 | 608
Diabetes Mellitus, Experimental 20 | 108
Global developmental delay 20 | 608
Heart failure 20 | 162
Mental and motor retardation 20 | 608
Muscle Spasticity 20 | 195
Bipolar Disorder 19 | 666
Cerebellar Ataxia 19 | 304
Diabetes Mellitus, Non-Insulin-Dependent 19 | 145
Fatty Liver 19 | 70
Heart disease 19 | 306
Hyperinsulinism 19 | 133
Liver diseases 19 | 87
Polycystic ovary syndrome 19 | 360
Prostatic Neoplasms 19 | 495
Retinitis Pigmentosa 19 | 226
Rheumatoid arthritis 19 | 1,191
Sensorineural Hearing Loss (disorder) 19 | 284
Feeding difficulties in infancy 18 | 175
Lens Opacities 18 | 231
Liver carcinoma 18 | 240
Low Vision 18 | 174
Nystagmus 18 | 317
Optic Atrophy 18 | 242
Visual Impairment 18 | 174
active ulcerative colitis 18 | 764
fibroadenoma 18 | 559

Tissue

Endocrine System 193 | 18,159
Digestive Tract 192 | 17,369
Liver and Pancreas 192 | 16,750
Female tissues 190 | 17,400
Skin and soft tissues 190 | 17,230
Blood and immune system 188 | 16,909
Urinary Tract 188 | 16,678
Male tissues 187 | 17,142
Nervous System 184 | 16,725
Respiratory system 184 | 16,393
Cardiovascular System 176 | 15,192

Target Family

Enzyme 99 | 4,145
Non-IDG 69 | 12,091
Nuclear Receptor 10 | 48
Transporter 8 | 473
Transcription Factor 6 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Microbody 195 | 195
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38
Fatty acyl-CoA reductase 1 FAR1 Tbio Enzyme -1.65427 43.8 27
Nucleoside diphosphate-linked moiety X motif 19 NUDT19 Tdark Non-IDG 0.90 0.09 79
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Peroxisomal membrane protein 4 PXMP4 Tdark Non-IDG -0.51334 4.00 99
Peroxisome assembly factor 2 PEX6 Tbio Enzyme -1.89379 79.8 148