Development Level

Tbio 107 | 10,625
Tchem 31 | 1,890
Tdark 17 | 7,003
Tclin 10 | 602

IMPC Term

decreased body weight 7 | 174
decreased total body fat amoun... 4 | 186
preweaning lethality, complete... 4 | 633
decreased circulating choleste... 3 | 85
decreased heart weight 3 | 44
increased circulating chloride... 3 | 43
abnormal behavior 2 | 226
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal tail morphology 2 | 17
abnormal tibia morphology 2 | 14
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased circulating creatini... 2 | 31
decreased lean body mass 2 | 195
enlarged heart 2 | 111
hypoactivity 2 | 89
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
abnormal body size 1 | 1
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating fructosa... 1 | 31
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
improved glucose tolerance 1 | 56
increased Ly6C high monocyte n... 1 | 12
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased granulocyte number 1 | 8
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
shortened RR interval 1 | 19
small testis 1 | 37
thick tail 1 | 1
thrombocytopenia 1 | 46

Disease

ovarian cancer 94 | 8,484
osteosarcoma 74 | 7,933
psoriasis 74 | 6,685
medulloblastoma, large-cell 60 | 6,234
glioblastoma 47 | 5,572
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,795
lung cancer 45 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,289
diabetes mellitus 40 | 1,663
atypical teratoid / rhabdoid tumor 39 | 4,369
ulcerative colitis 38 | 2,087
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,956
invasive ductal carcinoma 36 | 2,950
malignant mesothelioma 36 | 3,162
Obesity 32 | 616
Zellweger Syndrome 31 | 38
interstitial cystitis 30 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
Cancer 29 | 2,346
ductal carcinoma in situ 27 | 1,745
astrocytoma 26 | 1,493
ependymoma 26 | 2,514
lung adenocarcinoma 26 | 2,713
Metabolic syndrome X 25 | 155
oligodendroglioma 25 | 2,849
primitive neuroectodermal tumor 25 | 3,031
lung carcinoma 24 | 2,844
tuberculosis 24 | 1,557
Breast cancer 23 | 3,094
Multiple myeloma 22 | 1,327
astrocytic glioma 22 | 2,241
pancreatic cancer 22 | 2,300
pediatric high grade glioma 21 | 2,712
pituitary cancer 21 | 1,972
subependymal giant cell astrocytoma 21 | 2,287
Adrenoleukodystrophy 20 | 31
Peroxisomal disease 20 | 20
Pick disease 20 | 1,893
group 4 medulloblastoma 20 | 1,875
non-small cell lung cancer 20 | 2,798
posterior fossa group B ependymoma 20 | 1,530
Atherosclerosis 19 | 275
Atopic dermatitis 19 | 944
pilocytic astrocytoma 19 | 3,086
Chondrodysplasia punctata 18 | 41
Fatty liver disease 18 | 84
colon cancer 18 | 1,475
Hyperglycemia 17 | 120
Infantile refsum disease 17 | 19
Lipid metabolism disorder 17 | 102
acute quadriplegic myopathy 17 | 1,157
cystic fibrosis 16 | 1,665
Alzheimer's disease 15 | 644
Hypertensive disease 15 | 193
Kidney disease 15 | 396
Prostatic Neoplasms 15 | 471
Waldenstrons macroglobulinemia 15 | 765
Diabetes Mellitus, Experimental 14 | 106
Hypertension 14 | 287
Rheumatoid Arthritis 14 | 1,160
adrenocortical carcinoma 14 | 1,427
Adrenoleukodystrophy, Neonatal 13 | 13
Diabetes Mellitus, Non-Insulin-Dependent 13 | 157
Heart disease 13 | 279
Hyperinsulinism 13 | 63
Infantile Refsum Disease (disorder) 13 | 13
adult high grade glioma 13 | 2,148
Cerebrovascular disease 12 | 231
Coronary artery disease 12 | 240
Drug-Induced Liver Injury 12 | 118
Heart failure 12 | 80
Liver disease 12 | 219
Parkinson's disease 12 | 364
Refsum disease 12 | 21
active Crohn's disease 12 | 918
breast carcinoma 12 | 1,614
medulloblastoma 12 | 1,524
Fatty Liver 11 | 48
Liver carcinoma 11 | 217
Peroxisome biogenesis disorders 11 | 11
Polycystic Ovary Syndrome 11 | 332
Asthma 10 | 349
Cholestasis 10 | 93
Kidney Failure, Chronic 10 | 45
Osteoporosis 10 | 257
Reperfusion Injury 10 | 84
aldosterone-producing adenoma 10 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
posterior fossa group A ependymoma 10 | 1,511
primary pancreatic ductal adenocarcinoma 10 | 1,271
progressive supranuclear palsy 10 | 674
sonic hedgehog group medulloblastoma 10 | 1,482
Carcinoma 9 | 2,147
Colorectal Neoplasms 9 | 217
Down syndrome 9 | 548
Inflammation 9 | 109
Rhizomelic chondrodysplasia punctata 9 | 11
acute myeloid leukemia 9 | 780
cutaneous lupus erythematosus 9 | 1,056
nephrosclerosis 9 | 329

Tissue

Blood and immune system 164 | 17,995
Cardiovascular System 164 | 17,958
Digestive Tract 164 | 18,473
Endocrine System 164 | 18,512
Female tissues 164 | 18,647
Liver and Pancreas 164 | 18,136
Nervous System 164 | 18,561
Skin and soft tissues 164 | 18,115
Urinary Tract 164 | 18,444
Male tissues 163 | 17,969
Respiratory system 162 | 17,484

Target Family

Enzyme 93 | 4,146
Non-IDG 57 | 11,971
Nuclear Receptor 7 | 48
Transporter 6 | 473
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Microbody 165 | 165
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
Peroxisomal multifunctional enzyme type 2 HSD17B4 Tbio Non-IDG -2.15826 152.2 203
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Peroxisomal leader peptide-processing protease TYSND1 Tbio Enzyme -0.49732 3.53 45
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
Insulin-degrading enzyme IDE Tchem Enzyme -2.54789 384.2 283
Mitochondrial brown fat uncoupling protein 1 UCP1 Tbio Non-IDG -3.04555 1148.0 252
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Peroxisomal membrane protein 11A PEX11A Tbio Non-IDG -1.69751 54.6 104
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648