Development Level

Tbio 107 | 10,625
Tchem 31 | 1,890
Tdark 17 | 7,003
Tclin 10 | 602

IMPC Term

decreased body weight 7 | 174
decreased total body fat amoun... 4 | 186
preweaning lethality, complete... 4 | 633
decreased circulating choleste... 3 | 85
decreased heart weight 3 | 44
increased circulating chloride... 3 | 43
abnormal behavior 2 | 226
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal tail morphology 2 | 17
abnormal tibia morphology 2 | 14
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased circulating creatini... 2 | 31
decreased lean body mass 2 | 195
enlarged heart 2 | 111
hypoactivity 2 | 89
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
abnormal body size 1 | 1
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating fructosa... 1 | 31
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
improved glucose tolerance 1 | 56
increased Ly6C high monocyte n... 1 | 12
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased granulocyte number 1 | 8
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
shortened RR interval 1 | 19
small testis 1 | 37
thick tail 1 | 1
thrombocytopenia 1 | 46

Disease

ovarian cancer 94 | 8,492
osteosarcoma 74 | 7,933
psoriasis 74 | 6,685
medulloblastoma, large-cell 60 | 6,234
glioblastoma 47 | 5,572
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,795
lung cancer 45 | 4,473
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,289
diabetes mellitus 40 | 1,663
atypical teratoid / rhabdoid tumor 39 | 4,369
ulcerative colitis 38 | 2,087
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,956
invasive ductal carcinoma 36 | 2,950
malignant mesothelioma 36 | 3,163
Obesity 32 | 616
Zellweger Syndrome 31 | 38
interstitial cystitis 30 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
Cancer 29 | 2,346
ductal carcinoma in situ 27 | 1,745
astrocytoma 26 | 1,493
ependymoma 26 | 2,514
lung adenocarcinoma 26 | 2,714
Metabolic syndrome X 25 | 155
oligodendroglioma 25 | 2,849
primitive neuroectodermal tumor 25 | 3,031
lung carcinoma 24 | 2,844
tuberculosis 24 | 1,563
Breast cancer 23 | 3,099
Multiple myeloma 22 | 1,328
astrocytic glioma 22 | 2,241
pancreatic cancer 22 | 2,300
Infantile refsum disease 21 | 23
pediatric high grade glioma 21 | 2,712
pituitary cancer 21 | 1,972
subependymal giant cell astrocytoma 21 | 2,287
Adrenoleukodystrophy 20 | 31
Peroxisomal disease 20 | 20
Pick disease 20 | 1,893
group 4 medulloblastoma 20 | 1,875
non-small cell lung cancer 20 | 2,798
posterior fossa group B ependymoma 20 | 1,530
Atherosclerosis 19 | 275
Atopic dermatitis 19 | 944
Fatty liver disease 19 | 86
pilocytic astrocytoma 19 | 3,086
Chondrodysplasia punctata 18 | 41
colon cancer 18 | 1,475
Hyperglycemia 17 | 120
Lipid metabolism disorder 17 | 102
acute quadriplegic myopathy 17 | 1,157
cystic fibrosis 16 | 1,670
Alzheimer's disease 15 | 644
Hypertension 15 | 293
Hypertensive disease 15 | 193
Kidney disease 15 | 397
Prostatic Neoplasms 15 | 471
Waldenstrons macroglobulinemia 15 | 765
Diabetes Mellitus, Experimental 14 | 106
Neonatal adrenoleukodystrophy 14 | 14
Rheumatoid Arthritis 14 | 1,171
adrenocortical carcinoma 14 | 1,427
Adrenoleukodystrophy, Neonatal 13 | 13
Diabetes Mellitus, Non-Insulin-Dependent 13 | 161
Heart disease 13 | 279
Hyperinsulinism 13 | 63
Infantile Refsum Disease (disorder) 13 | 13
adult high grade glioma 13 | 2,148
Cerebrovascular disease 12 | 231
Coronary artery disease 12 | 240
Drug-Induced Liver Injury 12 | 118
Heart failure 12 | 80
Liver disease 12 | 219
Parkinson's disease 12 | 364
Refsum disease 12 | 21
active Crohn's disease 12 | 918
breast carcinoma 12 | 1,614
medulloblastoma 12 | 1,524
Fatty Liver 11 | 48
Liver carcinoma 11 | 217
Peroxisome Biogenesis Disorder 1A (Zellweger) 11 | 12
Peroxisome Biogenesis Disorder 3B 11 | 11
Peroxisome biogenesis disorders 11 | 11
Polycystic Ovary Syndrome 11 | 335
Asthma 10 | 349
Cholestasis 10 | 93
Kidney Failure, Chronic 10 | 45
Osteoporosis 10 | 259
Reperfusion Injury 10 | 84
aldosterone-producing adenoma 10 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
posterior fossa group A ependymoma 10 | 1,511
primary pancreatic ductal adenocarcinoma 10 | 1,271
progressive supranuclear palsy 10 | 674
sonic hedgehog group medulloblastoma 10 | 1,482
Carcinoma 9 | 2,147
Down syndrome 9 | 548
acute myeloid leukemia 9 | 785
cutaneous lupus erythematosus 9 | 1,056
nephrosclerosis 9 | 329

Tissue

Blood and immune system 164 | 17,995
Cardiovascular System 164 | 17,958
Digestive Tract 164 | 18,473
Endocrine System 164 | 18,512
Female tissues 164 | 18,647
Liver and Pancreas 164 | 18,136
Nervous System 164 | 18,561
Skin and soft tissues 164 | 18,115
Urinary Tract 164 | 18,444
Male tissues 163 | 17,969
Respiratory system 162 | 17,484

Target Family

Enzyme 93 | 4,146
Non-IDG 57 | 11,969
Nuclear Receptor 7 | 48
Transporter 6 | 473
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Microbody 165 | 165
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.72649 574.1 155
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.20444 1.52 22
Alpha-methylacyl-CoA racemase AMACR Tbio Enzyme -2.45535 296.1 443
3-ketoacyl-CoA thiolase, mitochondrial ACAA2 Tbio Enzyme -1.77673 54.1 135
Tetratricopeptide repeat protein 1 TTC1 Tbio Non-IDG -1.48841 30.8 122
Transmembrane protein 135 TMEM135 Tdark Non-IDG -0.56834 3.33 30
Peroxisomal 2,4-dienoyl-CoA reductase DECR2 Tbio Enzyme -1.34292 21.9 82
Glutathione S-transferase kappa 1 GSTK1 Tchem Enzyme -1.04892 10.3 219
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.66772 4499.1 1649
Fatty acid-binding protein, adipocyte FABP4 Tchem Non-IDG -2.68687 545.4 550