Development Level

Tbio 73 | 11,445
Tchem 26 | 1,598
Tdark 9 | 6,588
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 19 | 979
abnormal embryo size 6 | 220
preweaning lethality, incomple... 6 | 499
decreased total body fat amoun... 5 | 207
embryonic lethality prior to o... 5 | 239
abnormal behavior 4 | 298
increased lean body mass 4 | 172
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased bone mineral density 3 | 126
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
increased bone mineral density 3 | 72
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal pericardium morpholog... 2 | 26
abnormal retina morphology 2 | 71
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating creatini... 2 | 38
irregularly shaped pupil 2 | 7
male infertility 2 | 123
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tooth morphology 1 | 24
absent spleen 1 | 3
anophthalmia 1 | 33
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
edema 1 | 59
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased thermal nociceptive ... 1 | 9
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 77 | 11,493
ovarian cancer 64 | 8,520
osteosarcoma 54 | 7,950
group 3 medulloblastoma 45 | 4,104
Cancer 42 | 2,499
lung cancer 38 | 4,740
medulloblastoma, large-cell 36 | 6,241
psoriasis 34 | 6,694
atypical teratoid / rhabdoid tumor 32 | 5,112
malignant mesothelioma 30 | 3,232
Kidney cancer 28 | 2,613
glioblastoma 27 | 5,792
primitive neuroectodermal tumor 23 | 3,035
Breast cancer 21 | 3,578
Intellectual disability 20 | 1,016
ependymoma 19 | 4,679
invasive ductal carcinoma 18 | 2,951
Multiple myeloma 16 | 1,332
non-small cell lung cancer 16 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
adult high grade glioma 14 | 3,801
oligodendroglioma 14 | 2,850
Pick disease 13 | 1,894
astrocytic glioma 13 | 2,597
dermatomyositis 13 | 966
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Liver cancer 11 | 604
Schizophrenia 11 | 1,160
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
juvenile dermatomyositis 11 | 1,187
adrenocortical carcinoma 10 | 1,428
lung adenocarcinoma 10 | 2,716
Dull intelligence 9 | 645
Low intelligence 9 | 645
Melanoma 9 | 711
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
pancreatic cancer 9 | 2,398
Breast Neoplasms 8 | 445
Immune system cancer 8 | 140
Kabuki syndrome 8 | 27
Lymphoid leukemia 8 | 160
Mammary Neoplasms 8 | 425
Muscle hypotonia 8 | 571
breast carcinoma 8 | 1,638
pediatric high grade glioma 8 | 1,064
spina bifida 8 | 1,074
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
Adenoid Cystic Carcinoma 7 | 99
Carcinoma, Adenoid Cystic 7 | 99
Epilepsy 7 | 792
Short stature 7 | 531
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
ductal carcinoma in situ 7 | 1,745
Astrocytoma, Pilocytic 6 | 3,081
Autism spectrum disorder 6 | 101
Bladder Neoplasm 6 | 112
Cleft Palate 6 | 271
Cognitive delay 6 | 608
Failure to gain weight 6 | 365
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Neurodevelopmental Disorders 6 | 70
Pediatric failure to thrive 6 | 365
Stomach Neoplasms 6 | 300
Urinary Bladder Neoplasms 6 | 114
cystic fibrosis 6 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Acquired scoliosis 5 | 281
Alzheimer's disease 5 | 658
Autism Spectrum Disorders 5 | 75
Byzanthine arch palate 5 | 194
Conductive hearing loss 5 | 123
Congenital Epicanthus 5 | 177
Curvature of spine 5 | 282
Leukemia 5 | 104
Leukemia, Myelocytic, Acute 5 | 120
Orbital separation excessive 5 | 244
Seizures 5 | 596
Small head 5 | 374
Strabismus 5 | 270
acute myeloid leukemia 5 | 783
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
non primary Sjogren syndrome sicca 5 | 891
Broad flat nasal bridge 4 | 236
Endometrial cancer 4 | 311
Nasal bridge wide 4 | 236
Ventricular Septal Defects 4 | 119
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676

Tissue

Blood and immune system 110 | 16,909
Endocrine System 110 | 18,159
Female tissues 110 | 17,400
Male tissues 110 | 17,142
Respiratory system 110 | 16,393
Skin and soft tissues 110 | 17,230
Digestive Tract 109 | 17,369
Liver and Pancreas 109 | 16,750
Nervous System 109 | 16,725
Urinary Tract 109 | 16,678
Cardiovascular System 106 | 15,192

Target Family

Non-IDG 48 | 12,091
Epigenetic 39 | 242
Enzyme 15 | 4,145
TF/Epigenetic 4 | 38
Transcription Factor 4 | 1,400
Kinase 2 | 634

Compartment GO Term

Methyltransferase complex 112 | 112
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59
RNMT-activating mini protein FAM103A1 Tbio Non-IDG -0.24304 0.91 14
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
DPY30 domain-containing protein 1 DYDC1 Tbio Non-IDG -0.70377 5.09 133
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.48801 2.91 109
N6-adenosine-methyltransferase catalytic subunit METTL3 Tbio Enzyme -1.76174 60.5 94
Histone-lysine N-methyltransferase SETD7 SETD7 Tchem Epigenetic -2.13644 139.8 343
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125