Development Level

Tbio 75 | 10,625
Tchem 27 | 1,890
Tdark 10 | 7,003
Tclin 4 | 602

IMPC Term

preweaning lethality, complete... 9 | 633
decreased total body fat amoun... 6 | 186
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
decreased body length 3 | 108
decreased circulating HDL chol... 3 | 77
embryonic lethality prior to o... 3 | 148
increased grip strength 3 | 83
increased lean body mass 3 | 107
increased total body fat amoun... 3 | 57
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
cataract 2 | 26
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased rib number 2 | 59
hypoactivity 2 | 89
increased circulating creatini... 2 | 29
increased sacral vertebrae num... 2 | 62
male infertility 2 | 62
short tibia 2 | 82
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
corneal opacity 1 | 25
decreased body weight 1 | 174
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
fusion of vertebral arches 1 | 7
impaired pupillary reflex 1 | 14
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased cardiac muscle contr... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased heart rate 1 | 17
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
prenatal lethality prior to he... 1 | 64
prolonged PR interval 1 | 4
prolonged QRS complex duration 1 | 2
shortened PR interval 1 | 5
shortened RR interval 1 | 19
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 67 | 8,484
osteosarcoma 58 | 7,933
Cancer 43 | 2,346
lung cancer 37 | 4,466
medulloblastoma, large-cell 36 | 6,234
psoriasis 36 | 6,685
atypical teratoid / rhabdoid tumor 30 | 4,369
group 3 medulloblastoma 30 | 2,254
glioblastoma 29 | 5,572
malignant mesothelioma 28 | 3,162
Carcinoma 25 | 2,147
primitive neuroectodermal tumor 24 | 3,031
Multiple myeloma 19 | 1,327
Breast cancer 18 | 3,094
Intellectual disability 18 | 573
invasive ductal carcinoma 18 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
pediatric high grade glioma 17 | 2,712
ependymoma 16 | 2,514
non-small cell lung cancer 16 | 2,798
dermatomyositis 15 | 933
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
oligodendroglioma 15 | 2,849
Pick disease 14 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
Waldenstrons macroglobulinemia 13 | 765
lung adenocarcinoma 13 | 2,713
astrocytic glioma 12 | 2,241
acute quadriplegic myopathy 11 | 1,157
juvenile dermatomyositis 11 | 1,189
Rheumatoid Arthritis 10 | 1,160
adrenocortical carcinoma 10 | 1,427
diabetes mellitus 10 | 1,663
sonic hedgehog group medulloblastoma 10 | 1,482
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
colon cancer 9 | 1,475
group 4 medulloblastoma 9 | 1,875
medulloblastoma 9 | 1,524
spina bifida 9 | 1,064
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 1,557
Mammary Neoplasms 8 | 410
Melanoma 8 | 261
breast carcinoma 8 | 1,614
pancreatic cancer 8 | 2,300
Adenoid Cystic Carcinoma 7 | 99
Alzheimer's disease 7 | 644
adult high grade glioma 7 | 2,148
cystic fibrosis 7 | 1,665
ductal carcinoma in situ 7 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
pilocytic astrocytoma 7 | 3,086
Kabuki syndrome 6 | 27
Lupus erythematosus 6 | 80
Stomach Neoplasms 6 | 282
ulcerative colitis 6 | 2,087
Bladder Neoplasm 5 | 109
Leukemia 5 | 88
Liver carcinoma 5 | 217
Lymphoid leukemia 5 | 69
acute myeloid leukemia 5 | 780
lung carcinoma 5 | 2,844
non primary Sjogren syndrome sicca 5 | 840
primary pancreatic ductal adenocarcinoma 5 | 1,271
progressive supranuclear palsy 5 | 674
Adenocarcinoma 4 | 115
Adenoma 4 | 165
Asthma 4 | 349
Autistic Disorder 4 | 320
Craniofacial Abnormalities 4 | 147
Leukemia, Myelocytic, Acute 4 | 113
Lung Neoplasms 4 | 171
Sezary Syndrome 4 | 26
Squamous cell carcinoma of esophagus 4 | 82
Wolf-Hirschhorn syndrome 4 | 32
interstitial cystitis 4 | 2,299
nasopharyngeal carcinoma 4 | 1,056
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 1,511
posterior fossa group B ependymoma 4 | 1,530
Amyotrophic Lateral Sclerosis 3 | 431
Atopic dermatitis 3 | 944
Carcinoma, Transitional Cell 3 | 31
Corneal staphyloma 3 | 4
Crohn's disease 3 | 304
Down syndrome 3 | 548
Endometriosis 3 | 535
Glioma 3 | 65
Immune system cancer 3 | 38
Myeloid Leukemia 3 | 19
Neoplasm Invasiveness 3 | 127
Neoplastic Syndromes, Hereditary 3 | 48
Peripheral T-cell lymphoma 3 | 24
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 42
Prostatic Neoplasms 3 | 471
Vascular disease 3 | 281
active ulcerative colitis 3 | 477
hepatocellular carcinoma 3 | 532
non-small cell lung carcinoma 3 | 413

Tissue

Digestive Tract 114 | 18,473
Endocrine System 114 | 18,512
Female tissues 114 | 18,647
Liver and Pancreas 114 | 18,136
Blood and immune system 113 | 17,995
Cardiovascular System 113 | 17,958
Male tissues 113 | 17,969
Nervous System 113 | 18,561
Skin and soft tissues 112 | 18,115
Urinary Tract 112 | 18,444
Respiratory system 111 | 17,484

Target Family

Non-IDG 48 | 11,971
Epigenetic 39 | 242
Enzyme 18 | 4,146
TF/Epigenetic 4 | 38
Transcription Factor 4 | 1,400
Kinase 3 | 634

Compartment GO Term

Methyltransferase complex 116 | 116
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme 8561.3 896
Tumor suppressor ARF CDKN2A Tbio Non-IDG -3.90375 8561.3 896
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.50539 2727.0 1106
Menin MEN1 Tchem Non-IDG -3.19669 1706.1 336
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.13310 1415.1 1015
Histone-lysine N-methyltransferase EZH2 EZH2 Tchem Epigenetic -3.04311 1194.6 498
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG 1012.4 81
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.22924 1007.4 85
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OGT Tchem Enzyme -2.92944 916.6 217
Methylcytosine dioxygenase TET1 TET1 Tbio Enzyme -2.91558 843.1 141