Development Level

Tbio 199 | 11,445
Tchem 54 | 1,598
Tclin 35 | 613
Tdark 10 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 26 | 979
preweaning lethality, incomple... 16 | 499
abnormal behavior 10 | 298
decreased vertical activity 8 | 208
embryonic lethality prior to t... 8 | 278
decreased total body fat amoun... 7 | 207
abnormal heart morphology 6 | 162
decreased leukocyte cell numbe... 6 | 73
enlarged heart 6 | 210
decreased body weight 5 | 161
embryonic lethality prior to o... 5 | 239
hyperactivity 5 | 148
abnormal sleep behavior 4 | 70
abnormal vibrissa morphology 4 | 25
cardiovascular system phenotyp... 4 | 36
improved glucose tolerance 4 | 79
increased neutrophil cell numb... 4 | 46
increased startle reflex 4 | 112
thrombocytopenia 4 | 56
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
abnormal pericardium morpholog... 3 | 26
cataract 3 | 92
decreased circulating triglyce... 3 | 79
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
edema 3 | 59
hydrometra 3 | 53
increased blood urea nitrogen ... 3 | 48
increased body weight 3 | 25
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased heart weight 3 | 62
increased lymphocyte cell numb... 3 | 32
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
persistence of hyaloid vascula... 3 | 33
small superior vagus ganglion 3 | 74
abnormal cecum morphology 2 | 7
abnormal limb bud morphology 2 | 17
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal whole-body plethysmog... 2 | 4
absent pinna reflex 2 | 23
decreased grip strength 2 | 116
decreased heart rate variabili... 2 | 13
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged cecum 2 | 5
enlarged uterus 2 | 11
hemorrhage 2 | 23
increased circulating alkaline... 2 | 122
increased circulating iron lev... 2 | 30
increased circulating sodium l... 2 | 71
increased eosinophil cell numb... 2 | 11
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
irregularly shaped pupil 2 | 7
male infertility 2 | 123
premature death 2 | 5
prenatal lethality prior to he... 2 | 87
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal placenta morphology 1 | 5
abnormal sensory capabilities-... 1 | 8
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
absent vibrissae 1 | 12
brachydactyly 1 | 19
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
limb grasping 1 | 41
polycystic kidney 1 | 15
scaly skin 1 | 4
thick skin 1 | 4

Disease

Carcinoma 214 | 11,493
ovarian cancer 185 | 8,520
osteosarcoma 147 | 7,950
psoriasis 135 | 6,694
glioblastoma 133 | 5,792
lung cancer 126 | 4,740
medulloblastoma, large-cell 124 | 6,241
Cancer 120 | 2,499
atypical teratoid / rhabdoid tumor 105 | 5,112
ependymoma 100 | 4,679
lung carcinoma 100 | 2,843
Breast cancer 93 | 3,578
Astrocytoma, Pilocytic 88 | 3,081
invasive ductal carcinoma 85 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
malignant mesothelioma 80 | 3,232
group 3 medulloblastoma 79 | 4,104
lung adenocarcinoma 78 | 2,716
oligodendroglioma 77 | 2,850
pancreatic cancer 76 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 75 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
non-small cell lung cancer 74 | 2,890
subependymal giant cell astrocytoma 72 | 2,287
diabetes mellitus 71 | 1,728
interstitial cystitis 71 | 2,312
astrocytic glioma 70 | 2,597
adult high grade glioma 69 | 3,801
Kidney cancer 67 | 2,613
tuberculosis 60 | 2,010
ulcerative colitis 56 | 1,819
primitive neuroectodermal tumor 55 | 3,035
Autosomal recessive predisposition 52 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 52 | 1,962
cystic fibrosis 50 | 1,696
Schizophrenia 49 | 1,160
ductal carcinoma in situ 49 | 1,745
Alzheimer's disease 47 | 658
colon cancer 47 | 1,478
breast carcinoma 46 | 1,638
cutaneous lupus erythematosus 45 | 1,057
Pick disease 44 | 1,894
pituitary cancer 44 | 1,972
group 4 medulloblastoma 42 | 1,855
primary pancreatic ductal adenocarcinoma 41 | 1,109
dermatomyositis 39 | 966
Liver Cirrhosis, Experimental 38 | 769
Kidney disease 36 | 430
astrocytoma 36 | 1,146
juvenile dermatomyositis 36 | 1,187
Obesity 34 | 678
acute quadriplegic myopathy 34 | 1,158
gastric carcinoma 33 | 807
pediatric high grade glioma 33 | 1,064
adrenocortical carcinoma 32 | 1,428
Multiple myeloma 31 | 1,332
Epilepsy 30 | 792
Hypertension 30 | 396
Rheumatoid arthritis 30 | 1,191
primary Sjogren syndrome 29 | 735
Coronary artery disease 28 | 268
Duchenne muscular dystrophy 28 | 601
Multiple Sclerosis 27 | 540
active ulcerative colitis 27 | 764
esophageal adenocarcinoma 27 | 737
Bipolar Disorder 26 | 666
Down syndrome 26 | 499
Seizures 26 | 596
mucosa-associated lymphoid tissue lymphoma 26 | 484
Intellectual disability 25 | 1,016
spina bifida 25 | 1,074
Atherosclerosis 24 | 291
Cerebrovascular disease 24 | 238
Depressive disorder 24 | 409
Heart disease 24 | 306
Neurodegenerative disease 24 | 414
Vascular disease 24 | 319
Waldenstrons macroglobulinemia 24 | 765
Arthritis 23 | 290
Prostatic Neoplasms 23 | 495
active Crohn's disease 23 | 922
Cognitive delay 22 | 608
Dull intelligence 22 | 645
Global developmental delay 22 | 608
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental and motor retardation 22 | 608
Mental deficiency 22 | 645
Poor school performance 22 | 645
Anemia 21 | 365
Melanoma 21 | 711
aldosterone-producing adenoma 20 | 665
Lung disease 19 | 142
Parkinson's disease 19 | 392
fibroadenoma 19 | 559
sarcoidosis 19 | 370
Asthma 18 | 385
Mental Depression 18 | 333
Stomach Neoplasms 18 | 300
nasopharyngeal carcinoma 18 | 1,058

Tissue

Endocrine System 293 | 18,159
Digestive Tract 292 | 17,369
Female tissues 291 | 17,400
Skin and soft tissues 289 | 17,230
Nervous System 285 | 16,725
Male tissues 284 | 17,142
Blood and immune system 283 | 16,909
Liver and Pancreas 283 | 16,750
Urinary Tract 283 | 16,678
Respiratory system 282 | 16,393
Cardiovascular System 270 | 15,192

Target Family

Non-IDG 185 | 12,091
Enzyme 52 | 4,145
Kinase 27 | 634
Ion Channel 13 | 344
GPCR 10 | 408
Transporter 7 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

Compartment GO Term

Membrane region 298 | 298
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Caveolae-associated protein 4 CAVIN4 Tbio Non-IDG -1.43474 31.1 70
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
Brain and acute leukemia cytoplasmic protein BAALC Tbio Non-IDG -1.65293 47.9 117
MARVEL domain-containing protein 1 MARVELD1 Tbio Non-IDG -1.58692 39.1 60
Caveolae-associated protein 2 CAVIN2 Tbio Non-IDG -2.85477 685.4 84
Cell migration-inducing and hyaluronan-binding protein CEMIP Tbio Non-IDG -1.58210 41.5 144
Reticulon-4 receptor-like 2 RTN4RL2 Tbio Non-IDG -1.11916 14.5 90