Development Level

Tbio 117 | 10,625
Tchem 50 | 1,890
Tclin 28 | 602
Tdark 5 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

preweaning lethality, complete... 10 | 633
abnormal behavior 5 | 226
decreased body weight 5 | 174
increased body weight 5 | 42
preweaning lethality, incomple... 5 | 260
decreased grip strength 4 | 123
embryonic lethality prior to t... 4 | 187
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal limb bud morphology 2 | 15
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal vibrissa morphology 2 | 17
corneal opacity 2 | 25
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
hemorrhage 2 | 12
hypoactivity 2 | 89
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased grip strength 2 | 83
male infertility 2 | 62
premature death 2 | 5
abnormal QRS complex 1 | 25
abnormal coping response 1 | 12
abnormal eyelid morphology 1 | 6
abnormal femur morphology 1 | 14
abnormal forced expiratory flo... 1 | 1
abnormal hair growth 1 | 8
abnormal limb morphology 1 | 7
abnormal placenta morphology 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal skin coloration 1 | 18
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
absent teeth 1 | 4
absent vibrissae 1 | 14
brachydactyly 1 | 2
cardiovascular system phenotyp... 1 | 35
cyanosis 1 | 6
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased body temperature 1 | 2
decreased cardiac muscle contr... 1 | 5
decreased circulating HDL chol... 1 | 77
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased tidal volume 1 | 1
edema 1 | 11
enlarged adrenal glands 1 | 3
enlarged heart 1 | 111
enlarged kidney 1 | 7
enlarged spleen 1 | 26
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
hydrops fetalis 1 | 22
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased CD4-positive, alpha ... 1 | 15
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased rib number 1 | 41
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
microcephaly 1 | 3
narrow eye opening 1 | 15
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
respiratory system phenotype 1 | 2
shortened ST segment 1 | 9
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

ovarian cancer 137 | 8,491
osteosarcoma 103 | 7,933
glioblastoma 91 | 5,572
psoriasis 91 | 6,685
Cancer 89 | 2,346
lung cancer 82 | 4,473
medulloblastoma, large-cell 81 | 6,234
lung carcinoma 75 | 2,844
Breast cancer 63 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,289
invasive ductal carcinoma 62 | 2,950
pilocytic astrocytoma 61 | 3,086
lung adenocarcinoma 57 | 2,714
pancreatic cancer 57 | 2,300
diabetes mellitus 55 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,988
malignant mesothelioma 53 | 3,163
interstitial cystitis 52 | 2,299
non-small cell lung cancer 52 | 2,798
subependymal giant cell astrocytoma 51 | 2,287
atypical teratoid / rhabdoid tumor 50 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,956
ulcerative colitis 48 | 2,087
oligodendroglioma 47 | 2,849
pediatric high grade glioma 46 | 2,712
primary pancreatic ductal adenocarcinoma 40 | 1,271
cutaneous lupus erythematosus 39 | 1,056
Carcinoma 38 | 2,147
cystic fibrosis 38 | 1,670
group 4 medulloblastoma 38 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
colon cancer 37 | 1,475
tuberculosis 36 | 1,563
breast carcinoma 35 | 1,614
astrocytoma 34 | 1,493
astrocytic glioma 32 | 2,241
ductal carcinoma in situ 32 | 1,745
primitive neuroectodermal tumor 32 | 3,031
pituitary cancer 31 | 1,972
Alzheimer's disease 30 | 644
dermatomyositis 29 | 966
group 3 medulloblastoma 29 | 2,254
gastric carcinoma 28 | 832
juvenile dermatomyositis 28 | 1,189
posterior fossa group A ependymoma 28 | 1,511
Pick disease 27 | 1,893
Kidney disease 26 | 397
Obesity 26 | 616
acute quadriplegic myopathy 26 | 1,157
Rheumatoid Arthritis 25 | 1,170
adrenocortical carcinoma 25 | 1,427
Duchenne muscular dystrophy 24 | 602
Hypertension 24 | 293
ependymoma 24 | 2,514
primary Sjogren syndrome 24 | 788
Multiple myeloma 23 | 1,327
Heart disease 22 | 279
Prostatic Neoplasms 22 | 471
adult high grade glioma 22 | 2,148
Waldenstrons macroglobulinemia 21 | 764
atypical teratoid/rhabdoid tumor 21 | 1,095
active Crohn's disease 20 | 918
sonic hedgehog group medulloblastoma 20 | 1,482
Coronary artery disease 19 | 240
Multiple Sclerosis 19 | 498
Down syndrome 18 | 548
IGA Glomerulonephritis 18 | 454
esophageal adenocarcinoma 18 | 737
Atherosclerosis 17 | 275
Cerebrovascular disease 17 | 231
Neurodegenerative disease 17 | 383
Mammary Neoplasms 16 | 410
Schizophrenia 16 | 503
Vascular disease 16 | 281
active ulcerative colitis 16 | 477
posterior fossa group B ependymoma 16 | 1,530
Lung disease 15 | 136
fibroadenoma 15 | 557
medulloblastoma 15 | 1,524
mucosa-associated lymphoid tissue lymphoma 15 | 480
nasopharyngeal carcinoma 15 | 1,056
sarcoidosis 15 | 368
Arthritis 14 | 248
Asthma 14 | 349
Neoplasm Invasiveness 14 | 127
Stomach Neoplasms 14 | 282
aldosterone-producing adenoma 14 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 499
Brain disease 13 | 84
Lung Neoplasms 13 | 171
Anemia 12 | 252
Colorectal Neoplasms 12 | 217
Crohn's disease 12 | 304
Hypersensitivity reaction type II disease 12 | 235
Neoplasm Metastasis 12 | 138
Parkinson's disease 12 | 364
Polycystic Ovary Syndrome 12 | 334
Reperfusion Injury 12 | 84
Toxic encephalopathy 12 | 131
pancreatic carcinoma 12 | 567

Tissue

Blood and immune system 198 | 17,994
Cardiovascular System 198 | 17,957
Digestive Tract 198 | 18,472
Endocrine System 198 | 18,511
Liver and Pancreas 198 | 18,135
Nervous System 198 | 18,560
Urinary Tract 198 | 18,443
Female tissues 197 | 18,646
Male tissues 196 | 17,968
Respiratory system 196 | 17,483
Skin and soft tissues 196 | 18,114

Target Family

Non-IDG 107 | 11,969
Enzyme 42 | 4,146
Kinase 25 | 634
Ion Channel 11 | 341
GPCR 6 | 408
Transporter 6 | 473
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

Compartment GO Term

Membrane raft 200 | 200
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Alternative prion protein PRNP Tbio Non-IDG -3.44085 5471.9 0
AT-rich interactive domain-containing protein 3A ARID3A Tbio Transcription Factor -2.07434 111.0 153
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Proteinase-activated receptor 1 F2R Tclin GPCR -2.76897 534.6 399
Dipeptidyl peptidase 4 DPP4 Tclin Enzyme -3.60140 4091.0 900
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.81736 519.3 441
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.08349 1170.6 213
Caspase recruitment domain-containing protein 11 CARD11 Tbio Enzyme -2.12968 129.2 231