Development Level

Tbio 117 | 10,625
Tchem 50 | 1,890
Tclin 28 | 602
Tdark 5 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 10 | 633
abnormal behavior 5 | 226
decreased body weight 5 | 174
increased body weight 5 | 42
preweaning lethality, incomple... 5 | 260
decreased grip strength 4 | 123
embryonic lethality prior to t... 4 | 187
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal limb bud morphology 2 | 15
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal vibrissa morphology 2 | 17
corneal opacity 2 | 25
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
hemorrhage 2 | 12
hypoactivity 2 | 89
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased grip strength 2 | 83
male infertility 2 | 62
premature death 2 | 5
abnormal QRS complex 1 | 25
abnormal coping response 1 | 12
abnormal eyelid morphology 1 | 6
abnormal femur morphology 1 | 14
abnormal forced expiratory flo... 1 | 1
abnormal hair growth 1 | 8
abnormal limb morphology 1 | 7
abnormal placenta morphology 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal skin coloration 1 | 18
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
absent teeth 1 | 4
absent vibrissae 1 | 14
brachydactyly 1 | 2
cardiovascular system phenotyp... 1 | 35
cyanosis 1 | 6
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased body temperature 1 | 2
decreased cardiac muscle contr... 1 | 5
decreased circulating HDL chol... 1 | 77
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased tidal volume 1 | 1
edema 1 | 11
enlarged adrenal glands 1 | 3
enlarged heart 1 | 111
enlarged kidney 1 | 7
enlarged spleen 1 | 26
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
hydrops fetalis 1 | 22
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased CD4-positive, alpha ... 1 | 15
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased rib number 1 | 41
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
microcephaly 1 | 3
narrow eye opening 1 | 15
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
respiratory system phenotype 1 | 2
shortened ST segment 1 | 9
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

ovarian cancer 137 | 8,484
osteosarcoma 103 | 7,933
glioblastoma 91 | 5,572
psoriasis 91 | 6,685
Cancer 89 | 2,346
lung cancer 82 | 4,466
medulloblastoma, large-cell 81 | 6,234
lung carcinoma 75 | 2,844
Breast cancer 63 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,289
invasive ductal carcinoma 62 | 2,950
pilocytic astrocytoma 61 | 3,086
lung adenocarcinoma 57 | 2,713
pancreatic cancer 57 | 2,300
diabetes mellitus 55 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,988
interstitial cystitis 52 | 2,299
malignant mesothelioma 52 | 3,162
non-small cell lung cancer 52 | 2,798
subependymal giant cell astrocytoma 51 | 2,287
atypical teratoid / rhabdoid tumor 50 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,956
ulcerative colitis 48 | 2,087
oligodendroglioma 47 | 2,849
pediatric high grade glioma 46 | 2,712
primary pancreatic ductal adenocarcinoma 40 | 1,271
cutaneous lupus erythematosus 39 | 1,056
Carcinoma 38 | 2,147
cystic fibrosis 38 | 1,665
group 4 medulloblastoma 38 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
colon cancer 37 | 1,475
tuberculosis 36 | 1,557
breast carcinoma 35 | 1,614
astrocytoma 34 | 1,493
astrocytic glioma 32 | 2,241
ductal carcinoma in situ 32 | 1,745
primitive neuroectodermal tumor 32 | 3,031
pituitary cancer 31 | 1,972
Alzheimer's disease 30 | 644
dermatomyositis 29 | 933
group 3 medulloblastoma 29 | 2,254
gastric carcinoma 28 | 832
juvenile dermatomyositis 28 | 1,189
posterior fossa group A ependymoma 28 | 1,511
Pick disease 27 | 1,893
Kidney disease 26 | 396
Obesity 26 | 616
acute quadriplegic myopathy 26 | 1,157
Rheumatoid Arthritis 25 | 1,160
adrenocortical carcinoma 25 | 1,427
Duchenne muscular dystrophy 24 | 602
Hypertension 24 | 287
ependymoma 24 | 2,514
primary Sjogren syndrome 24 | 789
Multiple myeloma 23 | 1,327
Heart disease 22 | 279
Prostatic Neoplasms 22 | 471
adult high grade glioma 22 | 2,148
Waldenstrons macroglobulinemia 21 | 765
atypical teratoid/rhabdoid tumor 21 | 1,095
active Crohn's disease 20 | 918
sonic hedgehog group medulloblastoma 20 | 1,482
Coronary artery disease 19 | 240
Multiple Sclerosis 19 | 498
Down syndrome 18 | 548
IGA Glomerulonephritis 18 | 454
esophageal adenocarcinoma 18 | 737
Atherosclerosis 17 | 275
Cerebrovascular disease 17 | 231
Neurodegenerative disease 17 | 383
Mammary Neoplasms 16 | 410
Schizophrenia 16 | 501
Vascular disease 16 | 281
active ulcerative colitis 16 | 477
posterior fossa group B ependymoma 16 | 1,530
Lung disease 15 | 132
fibroadenoma 15 | 557
medulloblastoma 15 | 1,524
mucosa-associated lymphoid tissue lymphoma 15 | 480
nasopharyngeal carcinoma 15 | 1,056
sarcoidosis 15 | 358
Arthritis 14 | 248
Asthma 14 | 349
Neoplasm Invasiveness 14 | 127
Stomach Neoplasms 14 | 282
aldosterone-producing adenoma 14 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 499
Brain disease 13 | 83
Lung Neoplasms 13 | 171
Anemia 12 | 252
Colorectal Neoplasms 12 | 217
Crohn's disease 12 | 304
Hypersensitivity reaction type II disease 12 | 235
Neoplasm Metastasis 12 | 138
Parkinson's disease 12 | 364
Polycystic Ovary Syndrome 12 | 332
Reperfusion Injury 12 | 84
Toxic encephalopathy 12 | 131
pancreatic carcinoma 12 | 567

Tissue

Blood and immune system 198 | 17,995
Cardiovascular System 198 | 17,958
Digestive Tract 198 | 18,473
Endocrine System 198 | 18,512
Liver and Pancreas 198 | 18,136
Nervous System 198 | 18,561
Urinary Tract 198 | 18,444
Female tissues 197 | 18,647
Male tissues 196 | 17,969
Respiratory system 196 | 17,484
Skin and soft tissues 196 | 18,115

Target Family

Non-IDG 107 | 11,971
Enzyme 42 | 4,146
Kinase 25 | 634
Ion Channel 11 | 341
GPCR 6 | 406
Transporter 6 | 473
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

Compartment GO Term

Membrane raft 200 | 200
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Blood vessel epicardial substance BVES Tbio Non-IDG -1.46376 36.1 156
Serpin H1 SERPINH1 Tbio Non-IDG -3.13545 1424.1 295
Phosphoglycerate kinase 1 PGK1 Tchem Kinase -2.77086 576.3 300
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Prohibitin PHB Tbio Non-IDG -2.65435 467.0 464