Development Level

Tbio 148 | 11,651
Tchem 43 | 1,388
Tclin 34 | 612
Tdark 6 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 16 | 979
preweaning lethality, incomple... 13 | 499
abnormal behavior 8 | 298
decreased vertical activity 8 | 208
decreased leukocyte cell numbe... 6 | 73
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
abnormal vibrissa morphology 4 | 25
decreased body weight 4 | 161
enlarged heart 4 | 210
improved glucose tolerance 4 | 79
increased neutrophil cell numb... 4 | 46
abnormal bone structure 3 | 187
abnormal heart morphology 3 | 162
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
edema 3 | 59
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
increased blood urea nitrogen ... 3 | 48
increased body weight 3 | 25
increased heart weight 3 | 62
increased monocyte cell number 3 | 63
increased startle reflex 3 | 112
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal pericardium morpholog... 2 | 26
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
enlarged uterus 2 | 11
hemorrhage 2 | 23
hydrometra 2 | 53
increased eosinophil cell numb... 2 | 11
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased total body fat amoun... 2 | 134
irregularly shaped pupil 2 | 7
male infertility 2 | 123
premature death 2 | 5
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal epididymis morphology 1 | 42
abnormal eyelid morphology 1 | 7
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal head size 1 | 6
abnormal iris morphology 1 | 13
abnormal placenta morphology 1 | 5
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
corneal opacity 1 | 32
cyanosis 1 | 7
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
enlarged adrenal glands 1 | 3
enlarged cecum 1 | 5
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged PQ interval 1 | 5
scaly skin 1 | 4
small testis 1 | 58
thick skin 1 | 4

Disease

Carcinoma 163 | 11,493
ovarian cancer 146 | 8,520
osteosarcoma 117 | 7,950
glioblastoma 106 | 5,792
psoriasis 106 | 6,694
Cancer 103 | 2,499
lung cancer 100 | 4,740
medulloblastoma, large-cell 96 | 6,241
lung carcinoma 86 | 2,843
atypical teratoid / rhabdoid tumor 77 | 5,112
Breast cancer 76 | 3,578
Astrocytoma, Pilocytic 73 | 3,081
ependymoma 73 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 68 | 3,291
invasive ductal carcinoma 68 | 2,951
lung adenocarcinoma 67 | 2,716
group 3 medulloblastoma 66 | 4,104
pancreatic cancer 63 | 2,398
diabetes mellitus 62 | 1,728
malignant mesothelioma 62 | 3,232
interstitial cystitis 61 | 2,312
non-small cell lung cancer 61 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 60 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
oligodendroglioma 59 | 2,850
subependymal giant cell astrocytoma 59 | 2,287
adult high grade glioma 56 | 3,801
astrocytic glioma 51 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,962
Kidney cancer 47 | 2,613
tuberculosis 46 | 2,010
ulcerative colitis 46 | 1,819
colon cancer 44 | 1,478
cutaneous lupus erythematosus 44 | 1,057
Autosomal recessive predisposition 43 | 1,442
cystic fibrosis 43 | 1,696
Schizophrenia 42 | 1,160
breast carcinoma 40 | 1,638
primitive neuroectodermal tumor 39 | 3,035
ductal carcinoma in situ 37 | 1,745
pituitary cancer 36 | 1,972
primary pancreatic ductal adenocarcinoma 34 | 1,109
Alzheimer's disease 33 | 658
Liver Cirrhosis, Experimental 33 | 769
gastric carcinoma 32 | 807
group 4 medulloblastoma 32 | 1,855
dermatomyositis 31 | 966
juvenile dermatomyositis 31 | 1,187
Pick disease 30 | 1,894
Kidney disease 29 | 430
Obesity 29 | 678
acute quadriplegic myopathy 29 | 1,158
astrocytoma 29 | 1,146
Duchenne muscular dystrophy 28 | 601
Hypertension 28 | 396
adrenocortical carcinoma 28 | 1,428
Rheumatoid arthritis 26 | 1,191
active ulcerative colitis 26 | 764
Multiple Sclerosis 25 | 540
Bipolar Disorder 24 | 666
Coronary artery disease 24 | 268
Epilepsy 24 | 792
pediatric high grade glioma 24 | 1,064
primary Sjogren syndrome 24 | 735
Cerebrovascular disease 23 | 238
Multiple myeloma 23 | 1,332
Heart disease 22 | 306
Prostatic Neoplasms 22 | 495
Vascular disease 22 | 319
Waldenstrons macroglobulinemia 22 | 765
active Crohn's disease 22 | 922
Depressive disorder 21 | 409
Neurodegenerative disease 21 | 414
Seizures 21 | 596
Arthritis 20 | 290
Down syndrome 20 | 499
Atherosclerosis 19 | 291
esophageal adenocarcinoma 19 | 737
Lung disease 18 | 142
mucosa-associated lymphoid tissue lymphoma 18 | 484
Asthma 17 | 385
Melanoma 17 | 711
Mental Depression 17 | 333
Stomach Neoplasms 17 | 300
Anemia 16 | 365
Breast Neoplasms 16 | 445
Cognitive delay 16 | 608
Global developmental delay 16 | 608
Hypersensitivity reaction type II disease 16 | 253
Intellectual disability 16 | 1,016
Mammary Neoplasms 16 | 425
Mental and motor retardation 16 | 608
Parkinson's disease 16 | 392
aldosterone-producing adenoma 16 | 665
sarcoidosis 16 | 370
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510

Tissue

Digestive Tract 227 | 17,369
Endocrine System 227 | 18,159
Female tissues 225 | 17,400
Skin and soft tissues 225 | 17,230
Nervous System 223 | 16,725
Blood and immune system 221 | 16,909
Liver and Pancreas 221 | 16,750
Male tissues 220 | 17,142
Urinary Tract 220 | 16,678
Respiratory system 219 | 16,393
Cardiovascular System 210 | 15,192

Target Family

Non-IDG 129 | 12,091
Enzyme 45 | 4,145
Kinase 25 | 634
Ion Channel 14 | 344
GPCR 9 | 408
Transporter 6 | 473
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

Compartment GO Term

Membrane raft 231 | 231
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
E3 ubiquitin-protein ligase CBL-B CBLB Tbio Enzyme -0.82313 6.58 193
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform PPP2R1B Tbio Enzyme -1.20793 16.9 203
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.53932 4.30 895