Development Level

Tbio 3,655 | 11,445
Tdark 1,676 | 6,588
Tchem 756 | 1,598
Tclin 467 | 613

Collection

RFA-RM-18-021 208 | 328
GPCR: IDG Consortium (Targets) 124 | 126
Ion Channel: IDG Consortium (T... 91 | 99
GPCR: IDG Consortium (Complete... 25 | 25
Kinase: IDG Consortium (Target... 16 | 125
Kinase: IDG Consortium (Comple... 4 | 37

IMPC Phenotype

preweaning lethality, complete... 281 | 979
preweaning lethality, incomple... 168 | 499
abnormal behavior 116 | 298
embryonic lethality prior to t... 95 | 278
decreased total body fat amoun... 84 | 207
decreased vertical activity 83 | 208
embryonic lethality prior to o... 80 | 239
enlarged heart 79 | 210
abnormal embryo size 71 | 220
increased lean body mass 70 | 172
abnormal bone structure 68 | 187
hyperactivity 64 | 148
decreased body weight 60 | 161
decreased bone mineral content 60 | 151
increased total body fat amoun... 60 | 134
abnormal heart morphology 56 | 162
decreased lean body mass 50 | 135
abnormal seminal vesicle morph... 49 | 114
hypoactivity 47 | 132
increased circulating alkaline... 45 | 122
increased startle reflex 44 | 112
decreased bone mineral density 43 | 126
decreased grip strength 42 | 116
increased bone mineral content 39 | 108
increased or absent threshold ... 37 | 101
decreased circulating choleste... 36 | 93
decreased circulating glucose ... 36 | 126
embryonic growth retardation 36 | 106
decreased lymphocyte cell numb... 34 | 83
increased mean corpuscular hem... 34 | 96
increased mean corpuscular vol... 34 | 92
cataract 32 | 92
improved glucose tolerance 32 | 79
decreased circulating HDL chol... 31 | 68
abnormal gait 30 | 69
abnormal lens morphology 30 | 81
abnormal sleep behavior 30 | 70
decreased prepulse inhibition 30 | 82
impaired glucose tolerance 30 | 75
decreased body length 29 | 101
decreased circulating triglyce... 29 | 79
decreased fasted circulating g... 29 | 65
increased circulating sodium l... 29 | 71
decreased circulating insulin ... 28 | 76
decreased circulating serum al... 28 | 82
abnormal retina morphology 27 | 71
decreased hemoglobin content 27 | 68
increased fasted circulating g... 27 | 76
increased heart weight 27 | 62
increased monocyte cell number 27 | 63
small superior vagus ganglion 27 | 74
abnormal eye morphology 26 | 68
decreased mean corpuscular vol... 26 | 79
abnormal kidney morphology 25 | 65
decreased startle reflex 25 | 75
increased circulating HDL chol... 25 | 80
prenatal lethality prior to he... 25 | 87
short tibia 25 | 97
limb grasping 24 | 41
decreased leukocyte cell numbe... 23 | 73
male infertility 23 | 123
abnormal behavioral response t... 22 | 66
decreased circulating creatini... 22 | 39
decreased erythrocyte cell num... 22 | 62
abnormal epididymis morphology 21 | 42
increased bone mineral density 21 | 72
hydrometra 20 | 53
increased circulating choleste... 20 | 66
increased circulating triglyce... 20 | 42
increased neutrophil cell numb... 20 | 46
decreased circulating LDL chol... 19 | 38
decreased heart weight 19 | 27
thrombocytopenia 19 | 56
abnormal spleen morphology 18 | 55
cardiovascular system phenotyp... 18 | 36
decreased circulating alkaline... 18 | 46
edema 18 | 59
enlarged epididymis 18 | 31
increased blood urea nitrogen ... 18 | 48
increased circulating calcium ... 18 | 34
increased leukocyte cell numbe... 18 | 47
abnormal coat-hair pigmentatio... 17 | 64
abnormal neural tube closure 17 | 46
decreased mean corpuscular hem... 17 | 50
enlarged spleen 17 | 41
increased circulating chloride... 17 | 41
prolonged QT interval 17 | 38
tremors 17 | 39
abnormal skin morphology 16 | 50
decreased circulating alanine ... 16 | 47
decreased circulating total pr... 16 | 49
decreased neutrophil cell numb... 16 | 42
increased mean platelet volume 15 | 45
pallor 15 | 34
small testis 15 | 58
decreased circulating calcium ... 14 | 36
decreased red blood cell distr... 14 | 41
increased hemoglobin content 14 | 45
increased prepulse inhibition 14 | 32
prolonged ST segment 14 | 36

Disease

Carcinoma 4,198 | 11,493
ovarian cancer 2,799 | 8,520
osteosarcoma 2,623 | 7,950
psoriasis 2,372 | 6,694
medulloblastoma, large-cell 2,192 | 6,241
glioblastoma 2,144 | 5,792
atypical teratoid / rhabdoid tumor 1,875 | 5,112
ependymoma 1,722 | 4,679
lung cancer 1,646 | 4,740
adult high grade glioma 1,456 | 3,801
Astrocytoma, Pilocytic 1,340 | 3,081
lung carcinoma 1,292 | 2,843
group 3 medulloblastoma 1,261 | 4,104
Breast cancer 1,259 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 1,186 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 1,130 | 2,955
invasive ductal carcinoma 1,128 | 2,951
non-small cell lung cancer 1,100 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 1,089 | 2,989
lung adenocarcinoma 1,079 | 2,716
malignant mesothelioma 1,076 | 3,232
Cancer 1,072 | 2,499
oligodendroglioma 1,059 | 2,850
interstitial cystitis 1,050 | 2,312
primitive neuroectodermal tumor 1,026 | 3,035
Kidney cancer 999 | 2,613
pancreatic cancer 963 | 2,398
astrocytic glioma 935 | 2,597
subependymal giant cell astrocytoma 887 | 2,287
tuberculosis 835 | 2,010
pituitary cancer 788 | 1,972
ulcerative colitis 769 | 1,819
pancreatic ductal adenocarcinoma liver metastasis 757 | 1,962
diabetes mellitus 736 | 1,728
ductal carcinoma in situ 694 | 1,745
cystic fibrosis 690 | 1,696
Pick disease 685 | 1,894
group 4 medulloblastoma 663 | 1,855
Autosomal recessive predisposition 618 | 1,442
breast carcinoma 613 | 1,638
Schizophrenia 582 | 1,160
colon cancer 521 | 1,478
cutaneous lupus erythematosus 484 | 1,057
adrenocortical carcinoma 482 | 1,428
Rheumatoid arthritis 473 | 1,191
Multiple myeloma 442 | 1,332
astrocytoma 438 | 1,146
primary pancreatic ductal adenocarcinoma 436 | 1,109
active Crohn's disease 413 | 922
juvenile dermatomyositis 390 | 1,187
Epilepsy 384 | 792
pediatric high grade glioma 382 | 1,064
acute quadriplegic myopathy 381 | 1,158
Intellectual disability 363 | 1,016
active ulcerative colitis 350 | 764
Bipolar Disorder 343 | 666
Liver Cirrhosis, Experimental 338 | 769
Obesity 337 | 678
spina bifida 336 | 1,074
Alzheimer's disease 335 | 658
dermatomyositis 333 | 966
nasopharyngeal carcinoma 332 | 1,058
Melanoma 331 | 711
Atopic dermatitis 327 | 952
gastric carcinoma 312 | 807
non primary Sjogren syndrome sicca 311 | 891
primary Sjogren syndrome 305 | 735
esophageal adenocarcinoma 300 | 737
Multiple Sclerosis 297 | 540
Seizures 269 | 596
Kidney disease 268 | 430
Liver cancer 261 | 604
Duchenne muscular dystrophy 256 | 601
aldosterone-producing adenoma 255 | 665
medulloblastoma 255 | 720
Hypertension 247 | 396
Skin cancer 245 | 469
mucosa-associated lymphoid tissue lymphoma 243 | 484
Down syndrome 241 | 499
Dull intelligence 239 | 645
Low intelligence 239 | 645
Mental Retardation 239 | 645
Mental deficiency 239 | 645
Poor school performance 239 | 645
acute myeloid leukemia 231 | 783
Cognitive delay 230 | 608
Global developmental delay 230 | 608
Mental and motor retardation 230 | 608
Muscle hypotonia 230 | 571
Depressive disorder 227 | 409
fibroadenoma 226 | 559
Asthma 219 | 385
Waldenstrons macroglobulinemia 217 | 765
progressive supranuclear palsy 217 | 676
Anemia 211 | 365
Prostatic Neoplasms 209 | 495
pancreatic carcinoma 209 | 562
Arthritis 208 | 290
Hypersensitivity reaction type II disease 204 | 253
Parkinson's disease 201 | 392

Tissue

Endocrine System 5,976 | 18,159
Digestive Tract 5,737 | 17,369
Female tissues 5,721 | 17,400
Skin and soft tissues 5,648 | 17,230
Male tissues 5,637 | 17,142
Nervous System 5,547 | 16,725
Blood and immune system 5,545 | 16,909
Liver and Pancreas 5,536 | 16,750
Urinary Tract 5,529 | 16,678
Respiratory system 5,356 | 16,393
Cardiovascular System 4,910 | 15,192

Target Family

Non-IDG 3,433 | 12,091
Enzyme 1,282 | 4,145
Transporter 458 | 473
GPCR 397 | 408
oGPCR 380 | 421
Ion Channel 330 | 344
Kinase 195 | 634
Transcription Factor 63 | 1,400
Epigenetic 10 | 242
Nuclear Receptor 6 | 48

Compartment GO Term

Membrane part 6,554 | 6,554
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
UPF0606 protein KIAA1549 KIAA1549 Tbio Non-IDG -1.67668 47.8 19
WD repeat domain phosphoinositide-interacting protein 4 WDR45 Tbio Non-IDG -1.29355 17.4 93
GPI mannosyltransferase 4 PIGZ Tdark Enzyme -1.18571 13.8 39
Mitochondrial coenzyme A transporter SLC25A42 SLC25A42 Tbio Transporter -0.53750 4.06 29
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16