Development Level

Tbio 3,348 | 10,625
Tdark 1,812 | 7,003
Tchem 851 | 1,890
Tclin 459 | 602

Collection

GPCR: IDG Consortium (Targets) 124 | 127
Ion Channel: IDG Consortium (Targets) 94 | 102
GPCR: IDG Consortium (Complete/Control) 26 | 26
Kinase: IDG Consortium (Targets) 16 | 125
Kinase: IDG Consortium (Complete/Control) 4 | 37

IMPC Phenotype

preweaning lethality, complete... 187 | 633
abnormal behavior 83 | 226
preweaning lethality, incomple... 82 | 260
decreased total body fat amoun... 76 | 186
decreased lean body mass 71 | 195
embryonic lethality prior to t... 65 | 187
decreased bone mineral content 64 | 157
decreased body weight 63 | 174
decreased bone mineral density 50 | 126
abnormal bone structure 49 | 131
embryonic lethality prior to o... 46 | 148
increased circulating alkaline... 46 | 119
decreased grip strength 44 | 123
hyperactivity 43 | 108
increased lean body mass 42 | 107
increased mean corpuscular hem... 40 | 93
increased or absent threshold ... 39 | 128
enlarged heart 38 | 111
decreased circulating choleste... 34 | 85
decreased circulating glucose ... 34 | 121
decreased circulating triglyce... 34 | 83
hypoactivity 33 | 89
increased mean corpuscular vol... 33 | 91
abnormal embryo size 32 | 112
abnormal retina morphology 32 | 100
decreased circulating HDL chol... 31 | 77
decreased circulating insulin ... 30 | 75
increased bone mineral content 30 | 92
increased circulating sodium l... 30 | 71
decreased body length 28 | 108
increased grip strength 27 | 83
increased fasted circulating g... 25 | 68
abnormal lens morphology 24 | 73
abnormal sleep behavior 24 | 63
decreased circulating alanine ... 24 | 53
decreased circulating serum al... 24 | 79
decreased fasted circulating g... 24 | 49
decreased prepulse inhibition 24 | 52
increased total body fat amoun... 24 | 57
abnormal bone mineralization 23 | 55
abnormal gait 23 | 51
improved glucose tolerance 23 | 56
impaired glucose tolerance 21 | 52
increased exploration in new e... 21 | 56
abnormal retinal pigmentation 20 | 61
cardiovascular system phenotyp... 20 | 35
decreased heart weight 20 | 44
decreased hemoglobin content 20 | 53
decreased rib number 20 | 59
increased circulating HDL chol... 20 | 63
short tibia 20 | 82
decreased eosinophil cell numb... 19 | 41
decreased mean corpuscular vol... 19 | 50
increased blood urea nitrogen ... 19 | 44
abnormal seminal vesicle morph... 18 | 47
decreased caudal vertebrae num... 18 | 49
decreased lumbar vertebrae num... 18 | 62
increased bone mineral density 18 | 52
increased circulating calcium ... 18 | 32
increased circulating choleste... 18 | 53
increased circulating potassiu... 18 | 31
increased heart weight 18 | 37
limb grasping 18 | 35
decreased circulating LDL chol... 17 | 37
enlarged epididymis 17 | 27
increased body weight 17 | 42
increased hemoglobin content 17 | 45
increased sacral vertebrae num... 17 | 62
thrombocytopenia 17 | 46
abnormal eye morphology 16 | 38
abnormal neural tube closure 16 | 37
prenatal lethality prior to he... 16 | 64
tremors 16 | 34
abnormal epididymis morphology 15 | 31
abnormal heart morphology 15 | 51
decreased leukocyte cell numbe... 15 | 54
decreased startle reflex 15 | 48
increased rib number 15 | 41
male infertility 15 | 62
abnormal QRS complex 14 | 25
abnormal behavioral response t... 14 | 52
decreased NK T cell number 14 | 28
decreased circulating calcium ... 14 | 33
decreased circulating creatini... 14 | 31
decreased circulating free fat... 14 | 39
decreased erythrocyte cell num... 14 | 43
increased circulating chloride... 14 | 43
decreased circulating alkaline... 13 | 41
increased hematocrit 13 | 36
increased leukocyte cell numbe... 13 | 37
straub tail 13 | 26
abnormal kidney morphology 12 | 30
decreased T cell number 12 | 31
decreased circulating aspartat... 12 | 27
decreased circulating total pr... 12 | 41
decreased mean corpuscular hem... 12 | 34
decreased monocyte cell number 12 | 28
increased startle reflex 12 | 38
abnormal coat-hair pigmentatio... 11 | 54
decreased circulating fructosa... 11 | 31

Disease

ovarian cancer 2,737 | 8,491
osteosarcoma 2,585 | 7,933
psoriasis 2,353 | 6,685
medulloblastoma, large-cell 2,175 | 6,234
glioblastoma 2,046 | 5,572
atypical teratoid / rhabdoid tumor 1,586 | 4,369
lung cancer 1,503 | 4,473
pilocytic astrocytoma 1,337 | 3,086
lung carcinoma 1,279 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 1,177 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 1,120 | 2,956
invasive ductal carcinoma 1,120 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 1,078 | 2,988
lung adenocarcinoma 1,064 | 2,714
Breast cancer 1,061 | 3,098
non-small cell lung cancer 1,051 | 2,798
oligodendroglioma 1,051 | 2,849
pediatric high grade glioma 1,051 | 2,712
malignant mesothelioma 1,042 | 3,163
interstitial cystitis 1,034 | 2,299
primitive neuroectodermal tumor 1,023 | 3,031
Cancer 994 | 2,346
ependymoma 915 | 2,514
pancreatic cancer 911 | 2,300
subependymal giant cell astrocytoma 884 | 2,287
ulcerative colitis 873 | 2,087
Carcinoma 866 | 2,147
astrocytic glioma 784 | 2,241
pituitary cancer 781 | 1,972
adult high grade glioma 777 | 2,148
diabetes mellitus 692 | 1,663
ductal carcinoma in situ 691 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 688 | 1,795
Pick disease 684 | 1,893
cystic fibrosis 674 | 1,670
group 4 medulloblastoma 669 | 1,875
tuberculosis 641 | 1,563
posterior fossa group A ependymoma 627 | 1,511
group 3 medulloblastoma 607 | 2,254
breast carcinoma 592 | 1,614
astrocytoma 574 | 1,493
medulloblastoma 562 | 1,524
colon cancer 516 | 1,475
primary pancreatic ductal adenocarcinoma 490 | 1,271
adrenocortical carcinoma 479 | 1,427
cutaneous lupus erythematosus 477 | 1,056
sonic hedgehog group medulloblastoma 469 | 1,482
Rheumatoid Arthritis 463 | 1,170
posterior fossa group B ependymoma 463 | 1,530
Multiple myeloma 436 | 1,327
active Crohn's disease 408 | 918
atypical teratoid/rhabdoid tumor 392 | 1,095
juvenile dermatomyositis 388 | 1,189
acute quadriplegic myopathy 377 | 1,157
dermatomyositis 332 | 966
nasopharyngeal carcinoma 325 | 1,056
Atopic dermatitis 323 | 944
primary Sjogren syndrome 323 | 788
spina bifida 323 | 1,064
gastric carcinoma 319 | 832
Alzheimer's disease 318 | 644
Obesity 310 | 616
esophageal adenocarcinoma 295 | 737
non primary Sjogren syndrome sicca 286 | 840
Multiple Sclerosis 284 | 498
Schizophrenia 278 | 503
Down syndrome 259 | 548
Duchenne muscular dystrophy 255 | 602
aldosterone-producing adenoma 251 | 664
Kidney disease 248 | 397
mucosa-associated lymphoid tissue lymphoma 241 | 480
acute myeloid leukemia 224 | 785
fibroadenoma 224 | 557
active ulcerative colitis 221 | 477
progressive supranuclear palsy 216 | 674
Waldenstrons macroglobulinemia 214 | 764
pancreatic carcinoma 211 | 567
Epilepsy 209 | 346
Asthma 203 | 349
Prostatic Neoplasms 201 | 471
Intellectual disability 197 | 573
Hypersensitivity reaction type II disease 191 | 235
Hypertension 191 | 293
tuberculosis and treatment for 6 months 190 | 686
autosomal dominant Emery-Dreifuss muscular dystrophy 188 | 499
Endometriosis 187 | 535
IGA Glomerulonephritis 185 | 454
Arthritis 183 | 248
Parkinson's disease 183 | 364
non-small cell lung carcinoma 182 | 413
Autistic Disorder 180 | 320
Neurodegenerative disease 178 | 383
Atherosclerosis 163 | 275
hepatocellular carcinoma 163 | 550
Vascular disease 162 | 281
Mammary Neoplasms 160 | 410
Heart disease 158 | 279
Liver disease 157 | 219
Anemia 156 | 252
sarcoidosis 150 | 368

Tissue

Female tissues 6,192 | 18,646
Urinary Tract 6,150 | 18,443
Nervous System 6,130 | 18,560
Endocrine System 6,117 | 18,511
Digestive Tract 6,088 | 18,472
Skin and soft tissues 5,980 | 18,114
Liver and Pancreas 5,940 | 18,135
Blood and immune system 5,874 | 17,994
Cardiovascular System 5,868 | 17,957
Male tissues 5,826 | 17,968
Respiratory system 5,739 | 17,483

Target Family

Non-IDG 3,382 | 11,969
Enzyme 1,260 | 4,146
Transporter 459 | 473
GPCR 399 | 408
oGPCR 380 | 421
Ion Channel 327 | 341
Kinase 191 | 634
Transcription Factor 57 | 1,400
Epigenetic 9 | 242
Nuclear Receptor 5 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

Membrane part 6,470 | 6,470
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.96873 85.2 108
5-hydroxytryptamine receptor 1E HTR1E Tchem GPCR -1.54352 34.9 99
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.64647 44.8 131
UDP-glucuronosyltransferase 2B15 UGT2B15 Tchem Enzyme -1.77071 60.2 66
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.13194 126.3 290
Synapse differentiation-inducing gene protein 1-like SYNDIG1L Tdark Non-IDG -0.55764 3.83 4
Neuron-specific protein family member 1 NSG1 Tbio Non-IDG -1.10592 14.0 156
Protein Mpv17 MPV17 Tbio Non-IDG -1.63162 40.5 114
T-cell surface protein tactile CD96 Tbio Non-IDG -2.03517 108.7 142