Development Level

Tbio 97 | 11,445
Tdark 13 | 6,588
Tchem 8 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased total body fat amoun... 7 | 207
preweaning lethality, complete... 6 | 979
abnormal behavior 5 | 298
increased circulating alkaline... 5 | 122
preweaning lethality, incomple... 5 | 499
abnormal lens morphology 4 | 81
increased or absent threshold ... 4 | 101
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
cardiovascular system phenotyp... 3 | 36
cataract 3 | 92
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
decreased grip strength 3 | 116
decreased mean corpuscular hem... 3 | 50
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
abnormal bone structure 2 | 187
abnormal femur morphology 2 | 14
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal sensory capabilities-... 2 | 8
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
increased prepulse inhibition 2 | 32
increased startle reflex 2 | 112
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal liver morphology 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal spleen morphology 1 | 55
absent adrenal gland 1 | 2
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
tremors 1 | 39

Disease

ovarian cancer 81 | 8,520
Carcinoma 80 | 11,493
osteosarcoma 64 | 7,950
glioblastoma 52 | 5,792
medulloblastoma, large-cell 49 | 6,241
psoriasis 48 | 6,694
atypical teratoid / rhabdoid tumor 41 | 5,112
ependymoma 36 | 4,679
Breast cancer 32 | 3,578
adult high grade glioma 32 | 3,801
Astrocytoma, Pilocytic 28 | 3,081
Cancer 28 | 2,499
Pick disease 28 | 1,894
astrocytic glioma 28 | 2,597
lung cancer 28 | 4,740
Multiple myeloma 26 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
oligodendroglioma 26 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
malignant mesothelioma 25 | 3,232
primitive neuroectodermal tumor 25 | 3,035
group 3 medulloblastoma 24 | 4,104
Kidney cancer 21 | 2,613
pancreatic cancer 21 | 2,398
invasive ductal carcinoma 20 | 2,951
lung adenocarcinoma 20 | 2,716
subependymal giant cell astrocytoma 20 | 2,287
acute quadriplegic myopathy 19 | 1,158
diabetes mellitus 19 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
non-small cell lung cancer 18 | 2,890
Cataract 8 multiple types 17 | 33
tuberculosis 17 | 2,010
Autosomal recessive predisposition 16 | 1,442
Intellectual disability 16 | 1,016
Neurodegenerative disease 15 | 414
lung carcinoma 15 | 2,843
pituitary cancer 15 | 1,972
interstitial cystitis 14 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
dermatomyositis 13 | 966
juvenile dermatomyositis 13 | 1,187
Rheumatoid arthritis 12 | 1,191
Waldenstrons macroglobulinemia 11 | 765
astrocytoma 11 | 1,146
group 4 medulloblastoma 11 | 1,855
Alzheimer's disease 10 | 658
ductal carcinoma in situ 10 | 1,745
primary pancreatic ductal adenocarcinoma 10 | 1,109
Schizophrenia 9 | 1,160
adrenocortical carcinoma 9 | 1,428
pediatric high grade glioma 9 | 1,064
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Vascular disease 8 | 319
active Crohn's disease 8 | 922
breast carcinoma 8 | 1,638
cystic fibrosis 8 | 1,696
hereditary spastic paraplegia 8 | 318
pancreatic carcinoma 8 | 562
ulcerative colitis 8 | 1,819
Dull intelligence 7 | 645
Epilepsy 7 | 792
Kidney disease 7 | 430
Liver Cirrhosis, Experimental 7 | 769
Liver cancer 7 | 604
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Parkinson's disease 7 | 392
Poor school performance 7 | 645
colon cancer 7 | 1,478
esophageal adenocarcinoma 7 | 737
progressive supranuclear palsy 7 | 676
Amyotrophic lateral sclerosis 6 | 451
Breast Neoplasms 6 | 445
Gaucher disease type 1 6 | 180
Major Depressive Disorder 6 | 301
Muscle hypotonia 6 | 571
Paraplegia 6 | 74
Prenatal onset 6 | 139
Renal Cell Carcinoma 6 | 214
Seizures 6 | 596
Short stature 6 | 531
medulloblastoma 6 | 720
Acquired scoliosis 5 | 281
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Curvature of spine 5 | 282
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Heart disease 5 | 306
Neoplasm Invasiveness 5 | 161
Stomach Neoplasms 5 | 300
Unipolar Depression 5 | 250
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
posterior fossa group B ependymoma 5 | 416
substance-related disorder 5 | 162

Tissue

Female tissues 119 | 17,400
Digestive Tract 118 | 17,369
Skin and soft tissues 118 | 17,230
Endocrine System 116 | 18,159
Male tissues 116 | 17,142
Blood and immune system 115 | 16,909
Liver and Pancreas 115 | 16,750
Nervous System 115 | 16,725
Respiratory system 115 | 16,393
Urinary Tract 115 | 16,678
Cardiovascular System 112 | 15,192

Target Family

Non-IDG 96 | 12,091
Enzyme 15 | 4,145
Kinase 4 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

Compartment GO Term

Membrane coat 120 | 120
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.99617 101.2 222
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
AP-5 complex subunit sigma-1 AP5S1 Tdark Non-IDG 0.00000 4
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
AP-5 complex subunit zeta-1 AP5Z1 Tbio Transcription Factor -0.53740 2.90 61
Synergin gamma SYNRG Tdark Non-IDG -1.69335 48.2 24
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168