Development Level

Tbio 86 | 10,625
Tchem 11 | 1,890
Tdark 11 | 7,003
Tclin 2 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

decreased total body fat amoun... 5 | 186
increased or absent threshold ... 5 | 128
abnormal behavior 4 | 226
abnormal lens morphology 4 | 73
increased circulating alkaline... 4 | 119
increased circulating HDL chol... 3 | 63
abnormal bone structure 2 | 131
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
cataract 2 | 26
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating fructosa... 2 | 31
decreased circulating serum al... 2 | 79
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
hyperactivity 2 | 108
increased circulating LDL chol... 2 | 15
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 93
preweaning lethality, complete... 2 | 633
thrombocytopenia 2 | 46
abnormal QRS complex 1 | 25
abnormal femur morphology 1 | 14
abnormal nail morphology 1 | 7
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
absent pinna reflex 1 | 21
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased heart rate variabili... 1 | 11
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired pupillary reflex 1 | 14
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate 1 | 17
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
male infertility 1 | 62
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
straub tail 1 | 26
thrombocytosis 1 | 23
tremors 1 | 34

Disease

ovarian cancer 72 | 8,491
osteosarcoma 58 | 7,933
glioblastoma 50 | 5,572
medulloblastoma, large-cell 48 | 6,234
psoriasis 45 | 6,685
atypical teratoid / rhabdoid tumor 38 | 4,369
pilocytic astrocytoma 29 | 3,086
Cancer 27 | 2,346
lung cancer 27 | 4,473
Breast cancer 26 | 3,098
Pick disease 26 | 1,893
oligodendroglioma 26 | 2,849
pediatric high grade glioma 26 | 2,712
Multiple myeloma 24 | 1,327
primitive neuroectodermal tumor 24 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
astrocytoma 21 | 1,493
malignant mesothelioma 21 | 3,163
diabetes mellitus 19 | 1,663
ependymoma 19 | 2,514
invasive ductal carcinoma 19 | 2,950
lung adenocarcinoma 19 | 2,714
subependymal giant cell astrocytoma 19 | 2,287
pancreatic cancer 18 | 2,300
acute quadriplegic myopathy 17 | 1,157
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
non-small cell lung cancer 17 | 2,798
astrocytic glioma 16 | 2,241
Carcinoma 15 | 2,147
lung carcinoma 15 | 2,844
medulloblastoma 15 | 1,524
tuberculosis 15 | 1,563
adult high grade glioma 14 | 2,148
pituitary cancer 14 | 1,972
interstitial cystitis 13 | 2,299
posterior fossa group B ependymoma 13 | 1,530
dermatomyositis 12 | 966
Waldenstrons macroglobulinemia 11 | 764
juvenile dermatomyositis 11 | 1,189
primary pancreatic ductal adenocarcinoma 11 | 1,271
Alzheimer's disease 10 | 644
Neurodegenerative disease 10 | 383
ductal carcinoma in situ 10 | 1,745
group 3 medulloblastoma 10 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Rheumatoid Arthritis 9 | 1,170
adrenocortical carcinoma 9 | 1,427
group 4 medulloblastoma 9 | 1,875
posterior fossa group A ependymoma 9 | 1,511
ulcerative colitis 9 | 2,087
breast carcinoma 8 | 1,614
Kidney disease 7 | 397
Parkinson's disease 7 | 364
Vascular disease 7 | 281
active Crohn's disease 7 | 918
cystic fibrosis 7 | 1,670
esophageal adenocarcinoma 7 | 737
progressive supranuclear palsy 7 | 674
Intellectual disability 6 | 573
colon cancer 6 | 1,475
pancreatic carcinoma 6 | 567
sonic hedgehog group medulloblastoma 6 | 1,482
Atopic dermatitis 5 | 944
Down syndrome 5 | 548
Duchenne muscular dystrophy 5 | 602
Mammary Neoplasms 5 | 410
Menkes disease 5 | 20
Renal Cell Carcinoma 5 | 199
interstitial lung disease 5 | 292
substance-related disorder 5 | 104
Amyotrophic Lateral Sclerosis 4 | 432
Anemia 4 | 252
Bladder Neoplasm 4 | 109
Diffuse large B-cell lymphoma 4 | 42
Gaucher disease type 1 4 | 171
Heart disease 4 | 279
Neoplasm Invasiveness 4 | 127
Neuropathy 4 | 210
Obesity 4 | 616
Pain agnosia 4 | 99
Prostatic Neoplasms 4 | 471
Stomach Neoplasms 4 | 282
active ulcerative colitis 4 | 477
acute T cell leukemia 4 | 17
atypical teratoid/rhabdoid tumor 4 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
gastric cancer 4 | 436
hereditary spastic paraplegia 4 | 313
non primary Sjogren syndrome sicca 4 | 840
urothelial carcinoma 4 | 318
Myocardial Ischemia 3 | 169
Schizophrenia 3 | 503
acute myeloid leukemia 3 | 785
aldosterone-producing adenoma 3 | 664
cutaneous lupus erythematosus 3 | 1,056
gastric carcinoma 3 | 832
hepatocellular carcinoma 3 | 550
mucosa-associated lymphoid tissue lymphoma 3 | 480
spina bifida 3 | 1,064

Tissue

Endocrine System 110 | 18,511
Blood and immune system 109 | 17,994
Cardiovascular System 109 | 17,957
Digestive Tract 109 | 18,472
Female tissues 109 | 18,646
Liver and Pancreas 109 | 18,135
Nervous System 109 | 18,560
Male tissues 108 | 17,968
Skin and soft tissues 108 | 18,114
Urinary Tract 108 | 18,443
Respiratory system 107 | 17,483

Target Family

Non-IDG 85 | 11,969
Enzyme 16 | 4,146
Kinase 4 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341
Transcription Factor 1 | 1,400

Compartment GO Term

Membrane coat 110 | 110
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adaptin ear-binding coat-associated protein 2 NECAP2 Tdark Non-IDG 0.03 1.26 31
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.70375 8561.3 896
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Disabled homolog 2 DAB2 Tbio Non-IDG -2.24622 174.6 226
Synergin gamma SYNRG Tdark Non-IDG -1.66612 46.4 22
AP-1 complex subunit mu-1 AP1M1 Tbio Non-IDG -1.18893 12.9 104
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.11491 14.8 25
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.43606 268.0 77
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.62399 398.9 288
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.63101 403.7 216