Development Level

Tbio 5,213 | 11,651
Tdark 1,987 | 6,593
Tchem 815 | 1,388
Tclin 515 | 612

Collection

RFA-RM-18-021 232 | 328
GPCR: IDG Consortium (Targets) 124 | 126
Ion Channel: IDG Consortium (T... 96 | 99
Kinase: IDG Consortium (Target... 35 | 125
GPCR: IDG Consortium (Complete... 25 | 25
Kinase: IDG Consortium (Comple... 9 | 37

IMPC Phenotype

preweaning lethality, complete... 415 | 979
preweaning lethality, incomple... 241 | 499
abnormal behavior 149 | 298
embryonic lethality prior to t... 133 | 278
decreased vertical activity 106 | 208
decreased total body fat amoun... 105 | 207
embryonic lethality prior to o... 105 | 239
enlarged heart 102 | 210
abnormal embryo size 99 | 220
abnormal bone structure 91 | 187
decreased body weight 85 | 161
increased lean body mass 85 | 172
hyperactivity 83 | 148
decreased bone mineral content 82 | 151
increased total body fat amoun... 80 | 134
abnormal heart morphology 74 | 162
decreased lean body mass 66 | 135
decreased bone mineral density 63 | 126
hypoactivity 63 | 132
abnormal seminal vesicle morph... 60 | 114
increased startle reflex 59 | 112
decreased circulating glucose ... 54 | 126
decreased grip strength 54 | 116
increased circulating alkaline... 54 | 122
embryonic growth retardation 53 | 106
increased bone mineral content 50 | 108
decreased body length 49 | 101
increased mean corpuscular hem... 49 | 96
increased or absent threshold ... 49 | 101
decreased circulating choleste... 45 | 93
increased mean corpuscular vol... 43 | 92
short tibia 43 | 97
cataract 42 | 92
improved glucose tolerance 42 | 79
decreased circulating insulin ... 41 | 76
decreased lymphocyte cell numb... 41 | 83
decreased prepulse inhibition 41 | 82
decreased startle reflex 40 | 75
abnormal retina morphology 39 | 71
decreased fasted circulating g... 39 | 65
decreased mean corpuscular vol... 39 | 79
abnormal gait 38 | 69
abnormal lens morphology 38 | 81
impaired glucose tolerance 38 | 75
male infertility 38 | 123
prenatal lethality prior to he... 38 | 87
decreased circulating serum al... 37 | 82
increased fasted circulating g... 37 | 76
decreased circulating triglyce... 36 | 79
increased circulating sodium l... 36 | 71
increased monocyte cell number 36 | 63
abnormal sleep behavior 35 | 70
small superior vagus ganglion 35 | 74
decreased circulating HDL chol... 34 | 68
abnormal eye morphology 33 | 68
edema 33 | 59
increased heart weight 33 | 62
decreased hemoglobin content 32 | 68
decreased leukocyte cell numbe... 32 | 73
abnormal kidney morphology 31 | 65
increased bone mineral density 31 | 72
increased circulating HDL chol... 31 | 80
limb grasping 30 | 41
thrombocytopenia 28 | 56
abnormal behavioral response t... 27 | 66
decreased erythrocyte cell num... 27 | 62
abnormal coat-hair pigmentatio... 26 | 64
abnormal epididymis morphology 26 | 42
abnormal skin morphology 26 | 50
increased leukocyte cell numbe... 26 | 47
increased neutrophil cell numb... 26 | 46
abnormal spleen morphology 25 | 55
decreased circulating creatini... 25 | 39
decreased mean corpuscular hem... 25 | 50
increased circulating chloride... 25 | 41
hydrometra 24 | 53
increased circulating choleste... 24 | 66
increased hematocrit 24 | 46
prolonged QT interval 24 | 38
small testis 24 | 58
abnormal neural tube closure 23 | 46
increased blood urea nitrogen ... 23 | 48
increased circulating triglyce... 23 | 42
increased hemoglobin content 23 | 45
tremors 23 | 39
abnormal testis morphology 22 | 43
decreased hematocrit 22 | 46
cardiovascular system phenotyp... 21 | 36
decreased circulating LDL chol... 21 | 38
decreased circulating alanine ... 21 | 47
decreased circulating alkaline... 21 | 46
decreased circulating total pr... 21 | 49
enlarged epididymis 21 | 31
enlarged spleen 21 | 41
increased circulating calcium ... 21 | 34
prolonged ST segment 21 | 36
decreased heart weight 20 | 27
decreased neutrophil cell numb... 20 | 42
increased grip strength 19 | 41
pallor 19 | 34

Disease

Carcinoma 5,459 | 11,493
ovarian cancer 3,843 | 8,520
osteosarcoma 3,550 | 7,950
psoriasis 3,158 | 6,694
medulloblastoma, large-cell 2,953 | 6,241
glioblastoma 2,867 | 5,792
atypical teratoid / rhabdoid tumor 2,489 | 5,112
ependymoma 2,296 | 4,679
lung cancer 2,233 | 4,740
adult high grade glioma 1,942 | 3,801
Astrocytoma, Pilocytic 1,727 | 3,081
group 3 medulloblastoma 1,715 | 4,104
Breast cancer 1,679 | 3,578
lung carcinoma 1,630 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 1,583 | 3,291
invasive ductal carcinoma 1,498 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 1,489 | 2,955
malignant mesothelioma 1,483 | 3,232
non-small cell lung cancer 1,476 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 1,450 | 2,989
Cancer 1,434 | 2,499
oligodendroglioma 1,430 | 2,850
lung adenocarcinoma 1,408 | 2,716
primitive neuroectodermal tumor 1,366 | 3,035
Kidney cancer 1,318 | 2,613
interstitial cystitis 1,305 | 2,312
astrocytic glioma 1,276 | 2,597
pancreatic cancer 1,263 | 2,398
subependymal giant cell astrocytoma 1,172 | 2,287
tuberculosis 1,049 | 2,010
pituitary cancer 995 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 994 | 1,962
ulcerative colitis 983 | 1,819
diabetes mellitus 944 | 1,728
Pick disease 927 | 1,894
group 4 medulloblastoma 914 | 1,855
ductal carcinoma in situ 899 | 1,745
cystic fibrosis 890 | 1,696
breast carcinoma 808 | 1,638
Autosomal recessive predisposition 804 | 1,442
Schizophrenia 725 | 1,160
colon cancer 695 | 1,478
adrenocortical carcinoma 642 | 1,428
Rheumatoid arthritis 631 | 1,191
Multiple myeloma 615 | 1,332
cutaneous lupus erythematosus 605 | 1,057
astrocytoma 585 | 1,146
primary pancreatic ductal adenocarcinoma 585 | 1,109
juvenile dermatomyositis 527 | 1,187
pediatric high grade glioma 523 | 1,064
acute quadriplegic myopathy 518 | 1,158
active Crohn's disease 513 | 922
spina bifida 499 | 1,074
Epilepsy 483 | 792
Intellectual disability 479 | 1,016
dermatomyositis 464 | 966
Liver Cirrhosis, Experimental 448 | 769
nasopharyngeal carcinoma 445 | 1,058
non primary Sjogren syndrome sicca 444 | 891
active ulcerative colitis 443 | 764
Atopic dermatitis 438 | 952
esophageal adenocarcinoma 422 | 737
Alzheimer's disease 417 | 658
Obesity 416 | 678
gastric carcinoma 414 | 807
Bipolar Disorder 413 | 666
Melanoma 408 | 711
primary Sjogren syndrome 389 | 735
Multiple Sclerosis 352 | 540
aldosterone-producing adenoma 342 | 665
Seizures 341 | 596
Liver cancer 332 | 604
Duchenne muscular dystrophy 328 | 601
acute myeloid leukemia 328 | 783
medulloblastoma 328 | 720
Hypertension 324 | 396
Kidney disease 324 | 430
Waldenstrons macroglobulinemia 322 | 765
Dull intelligence 308 | 645
Low intelligence 308 | 645
Mental Retardation 308 | 645
Mental deficiency 308 | 645
Poor school performance 308 | 645
Cognitive delay 298 | 608
Global developmental delay 298 | 608
Mental and motor retardation 298 | 608
Down syndrome 297 | 499
Muscle hypotonia 296 | 571
fibroadenoma 296 | 559
mucosa-associated lymphoid tissue lymphoma 294 | 484
progressive supranuclear palsy 292 | 676
Skin cancer 290 | 469
pancreatic carcinoma 286 | 562
Prostatic Neoplasms 278 | 495
Depressive disorder 274 | 409
Neurodegenerative disease 270 | 414
Asthma 262 | 385
autosomal dominant Emery-Dreifuss muscular dystrophy 260 | 510
Parkinson's disease 253 | 392
Short stature 251 | 531

Tissue

Endocrine System 7,883 | 18,159
Digestive Tract 7,630 | 17,369
Female tissues 7,615 | 17,400
Skin and soft tissues 7,537 | 17,230
Male tissues 7,485 | 17,142
Blood and immune system 7,410 | 16,909
Liver and Pancreas 7,382 | 16,750
Nervous System 7,375 | 16,725
Urinary Tract 7,365 | 16,678
Respiratory system 7,168 | 16,393
Cardiovascular System 6,627 | 15,192

Target Family

Non-IDG 4,703 | 12,091
Enzyme 1,803 | 4,145
Transporter 461 | 473
GPCR 398 | 408
oGPCR 380 | 421
Ion Channel 339 | 344
Kinase 296 | 634
Transcription Factor 108 | 1,400
Epigenetic 27 | 242
Nuclear Receptor 11 | 48
TF/Epigenetic 4 | 38

Compartment GO Term

Membrane 8,530 | 8,530
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Calcium uptake protein 3, mitochondrial MICU3 Tdark Non-IDG -0.21085 1.14 50
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418