Development Level

Tbio 91 | 11,445
Tchem 19 | 1,598
Tclin 7 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 7 | 278
abnormal coat-hair pigmentatio... 6 | 64
embryonic lethality prior to o... 6 | 239
abnormal retina morphology 5 | 71
preweaning lethality, incomple... 5 | 499
decreased vertical activity 4 | 208
abnormal behavior 3 | 298
abnormal skin morphology 3 | 50
abnormal sleep behavior 3 | 70
decreased mean corpuscular hem... 3 | 50
increased circulating sodium l... 3 | 71
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased hemoglobin content 2 | 68
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal eye size 1 | 7
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal iris transilluminatio... 1 | 2
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal motor capabilities-co... 1 | 5
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
hydrometra 1 | 53
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating thyroxin... 1 | 7
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small superior vagus ganglion 1 | 74
small testis 1 | 58
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

ovarian cancer 76 | 8,520
Carcinoma 72 | 11,493
glioblastoma 63 | 5,792
osteosarcoma 60 | 7,950
ependymoma 51 | 4,679
medulloblastoma, large-cell 49 | 6,241
atypical teratoid / rhabdoid tumor 46 | 5,112
psoriasis 44 | 6,694
lung cancer 39 | 4,740
Cancer 36 | 2,499
Astrocytoma, Pilocytic 35 | 3,081
subependymal giant cell astrocytoma 35 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
malignant mesothelioma 34 | 3,232
invasive ductal carcinoma 31 | 2,951
oligodendroglioma 31 | 2,850
pancreatic cancer 31 | 2,398
Breast cancer 29 | 3,578
Multiple myeloma 29 | 1,332
adult high grade glioma 29 | 3,801
lung adenocarcinoma 29 | 2,716
astrocytic glioma 28 | 2,597
acute quadriplegic myopathy 27 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
lung carcinoma 27 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
non-small cell lung cancer 24 | 2,890
Oculocutaneous albinism 23 | 29
group 3 medulloblastoma 22 | 4,104
Hermansky-Pudlak syndrome 21 | 42
diabetes mellitus 21 | 1,728
pituitary cancer 21 | 1,972
primitive neuroectodermal tumor 21 | 3,035
ulcerative colitis 21 | 1,819
Autosomal recessive predisposition 20 | 1,442
Pick disease 19 | 1,894
pediatric high grade glioma 19 | 1,064
group 4 medulloblastoma 18 | 1,855
interstitial cystitis 18 | 2,312
cystic fibrosis 17 | 1,696
ductal carcinoma in situ 16 | 1,745
Schizophrenia 15 | 1,160
tuberculosis 15 | 2,010
astrocytoma 14 | 1,146
juvenile dermatomyositis 14 | 1,187
Kidney cancer 13 | 2,613
Melanoma 13 | 711
Nystagmus 13 | 317
Vascular disease 13 | 319
Waldenstrons macroglobulinemia 13 | 765
active Crohn's disease 13 | 922
cutaneous lupus erythematosus 13 | 1,057
Duchenne muscular dystrophy 12 | 601
Liver Cirrhosis, Experimental 12 | 769
Parkinson's disease 12 | 392
breast carcinoma 12 | 1,638
dermatomyositis 12 | 966
gastric carcinoma 12 | 807
Platelet storage pool deficiency 11 | 21
Rheumatoid arthritis 11 | 1,191
primary pancreatic ductal adenocarcinoma 11 | 1,109
Alzheimer's disease 10 | 658
Neurodegenerative disease 10 | 414
Prostatic Neoplasms 10 | 495
Bipolar Disorder 9 | 666
Carcinoma, Hepatocellular 9 | 228
Chediak-Higashi syndrome 9 | 26
Down syndrome 9 | 499
Griscelli syndrome 9 | 24
Intellectual disability 9 | 1,016
Low Vision 9 | 174
Photodysphoria 9 | 121
Photophobia 9 | 121
Skin cancer 9 | 469
Strabismus 9 | 270
Visual Impairment 9 | 174
colon cancer 9 | 1,478
nasopharyngeal carcinoma 9 | 1,058
Achromasia 8 | 11
Albinism 8 | 11
Epilepsy 8 | 792
Liver carcinoma 8 | 240
Ocular albinism 8 | 26
Pigmentary iris degeneration 8 | 20
Vitiligo 8 | 73
adrenocortical carcinoma 8 | 1,428
non primary Sjogren syndrome sicca 8 | 891
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Depression 7 | 333
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Myocardial Ischemia 7 | 169
Poor school performance 7 | 645
fibroadenoma 7 | 559
spina bifida 7 | 1,074

Tissue

Endocrine System 116 | 18,159
Female tissues 116 | 17,400
Skin and soft tissues 116 | 17,230
Urinary Tract 115 | 16,678
Liver and Pancreas 114 | 16,750
Male tissues 114 | 17,142
Blood and immune system 113 | 16,909
Digestive Tract 113 | 17,369
Nervous System 113 | 16,725
Respiratory system 113 | 16,393
Cardiovascular System 109 | 15,192

Target Family

Non-IDG 65 | 12,091
Enzyme 42 | 4,145
Transporter 8 | 473
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

Compartment GO Term

Melanosome 120 | 120
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Staphylococcal nuclease domain-containing protein 1 SND1 Tbio Epigenetic -2.35812 225.9 175
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Erythrocyte band 7 integral membrane protein STOM Tbio Non-IDG -2.27504 176.9 163
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
Biogenesis of lysosome-related organelles complex 1 subunit 3 BLOC1S3 Tbio Non-IDG -0.81676 0.00000 66