Development Level

Tbio 35 | 11,445
Tdark 5 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
embryonic lethality prior to o... 4 | 239
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
increased or absent threshold ... 2 | 101
pale yolk sac 2 | 25
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal motor capabilities-co... 1 | 5
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal tail bud morphology 1 | 8
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
increased body length 1 | 32
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
pale liver 1 | 6
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
small spleen 1 | 19
small superior vagus ganglion 1 | 74

Disease

osteosarcoma 30 | 7,950
ovarian cancer 25 | 8,520
Carcinoma 22 | 11,493
medulloblastoma, large-cell 14 | 6,241
psoriasis 14 | 6,694
group 3 medulloblastoma 11 | 4,104
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
Kidney cancer 7 | 2,613
astrocytic glioma 7 | 2,597
ependymoma 7 | 4,679
lung cancer 7 | 4,740
malignant mesothelioma 7 | 3,232
oligodendroglioma 7 | 2,850
Rheumatoid arthritis 6 | 1,191
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Breast cancer 5 | 3,578
Endometriosis 5 | 540
Liver cancer 5 | 604
Pick disease 5 | 1,894
astrocytoma 5 | 1,146
group 4 medulloblastoma 5 | 1,855
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
Intellectual disability 4 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
tuberculosis and treatment for 6 months 4 | 409
Breast Neoplasms 3 | 445
Cancer 3 | 2,499
Epilepsy 3 | 792
Mammary Neoplasms 3 | 425
Multiple myeloma 3 | 1,332
Schizophrenia 3 | 1,160
Seizures 3 | 596
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Autosomal recessive predisposition 2 | 1,442
Chronic myeloid leukemia 2 | 12
Cognitive delay 2 | 608
Congenital heart disease 2 | 93
Deglutition Disorders 2 | 132
Depressive disorder 2 | 409
Diffuse cerebral atrophy 2 | 8
Dull intelligence 2 | 645
Endometrial cancer 2 | 311
FG syndrome 2 | 16
Feeding difficulties 2 | 127
Global developmental delay 2 | 608
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Depression 2 | 333
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Neurodegenerative disease 2 | 414
Ohdo syndrome 2 | 5
Philadelphia chromosome-positive acute lymphoblastic leukemia 2 | 47
Physical aggression 2 | 76
Poor school performance 2 | 645
Progressive disorder 2 | 142
Waldenstrons macroglobulinemia 2 | 765
Xeroderma pigmentosum group B 2 | 20
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 3 months 2 | 179
ulcerative colitis 2 | 1,819
Action Tremor 1 | 22
Anteriorly placed anus 1 | 7
Apraxias 1 | 27
Biotinidase deficiency 1 | 14
Birthmark 1 | 35
Cafe-au-Lait Spots 1 | 37
Claw hand 1 | 26
Clonus 1 | 18
Deep philtrum 1 | 21
Depressed philtrum 1 | 21
Generalized hypotonia 1 | 37
Herpes simplex 1 | 18
Hypernasal voice 1 | 39
Hypoplasia of scrotum 1 | 24
Joint laxity 1 | 54
Narrow nose 1 | 20
Nasal voice 1 | 39
Pinched nasal bridge 1 | 14
Postnatal microcephaly 1 | 24
Single transverse palmar crease 1 | 29
Terminal tremor 1 | 20

Tissue

Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678

Target Family

Enzyme 31 | 4,145
Non-IDG 7 | 12,091
Kinase 3 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Mediator complex 42 | 42
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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