Development Level

Tbio 12 | 10,625
Tdark 9 | 7,003
Tchem 1 | 1,890

IMPC Phenotype

preweaning lethality, complete... 4 | 633
abnormal coat-hair pigmentatio... 1 | 54
abnormal seminal vesicle morph... 1 | 47
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
impaired glucose tolerance 1 | 52
increased grip strength 1 | 83
prenatal lethality prior to he... 1 | 64

Disease

osteosarcoma 11 | 7,933
ovarian cancer 10 | 8,491
Congenital disorder of glycosylation 8 | 53
glioblastoma 7 | 5,572
psoriasis 6 | 6,685
Congenital muscular dystrophy 5 | 25
medulloblastoma, large-cell 5 | 6,234
Breast cancer 4 | 3,098
lung cancer 4 | 4,473
lung carcinoma 4 | 2,844
malignant mesothelioma 4 | 3,163
pilocytic astrocytoma 4 | 3,086
Intellectual disability 3 | 573
Lissencephaly 3 | 61
Microcephaly 3 | 149
Multiple myeloma 3 | 1,327
Muscular dystrophy 3 | 48
Walker-Warburg syndrome 3 | 18
atypical teratoid/rhabdoid tumor 3 | 1,095
ependymoma 3 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
non primary Sjogren syndrome sicca 3 | 840
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
Alpha 1-antitrypsin deficiency 2 | 10
Congenital muscular dystrophy (disorder) 2 | 8
Hydrocephalus 2 | 60
Muscle eye brain disease 2 | 8
Muscle-eye-brain disease 2 | 8
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain and Eye Anomalies), Type A, 1 2 | 6
Paroxysmal nocturnal hemoglobinuria 2 | 11
Rheumatoid Arthritis 2 | 1,170
Walker-Warburg congenital muscular dystrophy 2 | 14
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
limb-girdle muscular dystrophy 2 | 36
lung adenocarcinoma 2 | 2,714
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
primitive neuroectodermal tumor 2 | 3,031
sonic hedgehog group medulloblastoma 2 | 1,482
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
ulcerative colitis 2 | 2,087
Amyotrophic lateral sclerosis type 3 1 | 15
Bipolar Disorder 1 | 266
Botulism 1 | 20
Carpenter syndrome 1 | 13
Chromosome 17q12 deletion syndrome 1 | 16
Congenital disorder of glycosylation 1G 1 | 1
Congenital disorder of glycosylation 1K 1 | 1
Congenital disorder of glycosylation type 1G 1 | 1
Congenital disorder of glycosylation type 1K 1 | 1
Congenital muscular dystrophy-dystroglycanopathy with brain and eye anomalies, type A2 1 | 1
Congenital myasthenic syndrome 1 | 28
Cystinosis 1 | 15
Disease Progression 1 | 125
Early infantile epileptic encephalopathy with suppression bursts 1 | 18
Erythromelalgia 1 | 8
Fukuyama congenital muscular dystrophy 1 | 6
Gaucher's disease 1 | 25
Hepatic vein thrombosis 1 | 8
Hirschsprung's disease 1 | 44
Intracranial aneurysm 1 | 20
Juvenile Myelomonocytic Leukemia 1 | 21
Leber congenital amaurosis 1 | 72
Limb-girdle muscular dystrophy-dystroglycanopathy, type C1 1 | 1
Limb-girdle muscular dystrophy-dystroglycanopathy, type C2 1 | 1
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K 1 | 1
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE ANOMALIES), TYPE A, 2 1 | 1
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 1 1 | 1
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 2 1 | 1
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (LIMB-GIRDLE), TYPE C, 2 1 | 1
Mammary Neoplasms 1 | 410
Muscle biopsy shows dystrophic changes 1 | 2
Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A1 1 | 1
Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A2 1 | 1
Muscular dystrophy-dystroglycanopathy congenital with mental retardation B1 1 | 1
Muscular dystrophy-dystroglycanopathy congenital with mental retardation B2 1 | 1
Muscular dystrophy-dystroglycanopathy limb-girdle C1 1 | 1
Muscular dystrophy-dystroglycanopathy limb-girdle C2 1 | 1
Myelofibrosis 1 | 13
Myopathy 1 | 128
Neoplastic Cell Transformation 1 | 81
Neuropathy 1 | 210
Ohtahara syndrome 1 | 4
Polycythemia Vera 1 | 24
Portal vein thrombosis 1 | 9
Presbyopia 1 | 19
Prostatic Intraepithelial Neoplasias 1 | 11
Ptosis 1 | 42
Pyelonephritis 1 | 12
Stomach Neoplasms 1 | 282
Thrombocytosis 1 | 8
Venous Thrombosis 1 | 21
Williams-Beuren syndrome 1 | 45
sarcoidosis 1 | 368

Tissue

Blood and immune system 22 | 17,994
Cardiovascular System 22 | 17,957
Digestive Tract 22 | 18,472
Endocrine System 22 | 18,511
Female tissues 22 | 18,646
Liver and Pancreas 22 | 18,135
Male tissues 22 | 17,968
Nervous System 22 | 18,560
Respiratory system 22 | 17,483
Skin and soft tissues 22 | 18,114
Urinary Tract 22 | 18,443

Target Family

Enzyme 19 | 4,146
Non-IDG 2 | 11,969
Kinase 1 | 634

Compartment GO Term

Mannosyltransferase complex 22 | 22
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

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