Development Level

Tbio 5 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

increased circulating total pr... 1 | 28

Disease

osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Carcinoma 3 | 11,493
adult high grade glioma 3 | 3,801
medulloblastoma, large-cell 3 | 6,241
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
11 pairs of ribs 1 | 7
Abnormal foot bone ossification 1 | 3
Abnormal lung lobation 1 | 10
Abnormal maturation of the pelvis bone 1 | 3
Abnormal ossification involving bones of the feet 1 | 3
Abnormal ossification involving the femoral head and neck 1 | 2
Abnormal pelvis bone ossification 1 | 3
Abnormal vertebral ossification 1 | 5
Abnormality of cholesterol metabolism 1 | 3
Abnormality of the calcaneus 1 | 2
Abnormality of the gastric mucosa 1 | 2
Abnormality of the vertebral spinous processes 1 | 1
Absent or minimally ossified vertebral bodies 1 | 3
Absent toenails (anonychia) 1 | 7
Anterior rib punctate calcifications 1 | 1
Argentine hemorrhagic fever 1 | 10
Arthropathy 1 | 43
Barrel chest 1 | 12
Biliary cirrhosis 1 | 45
Bone marrow hypocellularity 1 | 20
CREST Syndrome 1 | 16
Calcification of trachea 1 | 3
Calcinosis 1 | 70
Calvarial defect 1 | 10
Cardiac arrest 1 | 36
Cranial defect 1 | 10
Decreased projection of midface 1 | 105
Defect of skull ossification 1 | 10
Diaphyseal thickening 1 | 11
Dry Eye Syndromes 1 | 8
Extramedullary Hematopoiesis (disorder) 1 | 5
Extramedullary erythropoiesis 1 | 5
Gastrointestinal Hemorrhage 1 | 52
HEM dysplasia 1 | 1
Hepatic calcification 1 | 2
Hepatosplenomegaly 1 | 22
Hereditary spherocytosis type 1 1 | 23
Horizontal sacrum 1 | 3
Hydrops Fetalis, Non-Immune 1 | 8
Hypoplastic fingernails 1 | 11
Hypoplastic vertebral bodies 1 | 7
Hyposegmentation of neutrophil nuclei 1 | 2
Hypotrophic midface 1 | 105
Increased bilirubin level (finding) 1 | 18
Irregular hyperpigmentation 1 | 33
Islets of Langerhans hyperplasia 1 | 11
Keratitis sicca 1 | 6
Keratoconjunctivitis sicca 1 | 25
Laryngeal calcification 1 | 2
Lethal skeletal dysplasia 1 | 6
Long clavicle 1 | 7
Meibomian cyst 1 | 4
Mesomelia 1 | 8
Metaphyseal cupping 1 | 10
Midface retrusion 1 | 105
Misalignment of teeth 1 | 8
Mucosal telangiectasiae 1 | 14
Multiple fractures present at birth 1 | 5
Myalgia 1 | 54
Neonatal Death 1 | 14
Onset of lymphedema around puberty 1 | 21
Palmar telangiectasia 1 | 2
Paranoid personality disorder 1 | 5
Patchy variation in bone mineral density 1 | 1
Pelger-Huet anomaly 1 | 8
Platyspondyly 1 | 56
Pleural effusion disorder 1 | 6
Progeria 1 | 25
Punctate vertebral calcifications 1 | 2
Reynolds syndrome 1 | 1
Sandal gap 1 | 24
Schizotypal personality disorder 1 | 7
Sclerodactyly 1 | 1
Scleroderma 1 | 7
Scleroderma-like secondary cutaneous sclerosis 1 | 7
Sclerosis of skull base 1 | 5
Severe hydrops fetalis 1 | 1
Severe short-limb dwarfism 1 | 4
Short phalanx of finger 1 | 32
Short ribs 1 | 30
Skull defect 1 | 10
Small midface 1 | 105
Spade-like hand 1 | 16
Splayed metaphyses 1 | 19
Sternal punctate calcifications 1 | 1
Stillbirth 1 | 17
Supernumerary vertebral ossification centers 1 | 2
White blood cell abnormality 1 | 1
Xerophthalmia 1 | 16
Xerostomia 1 | 42
joint abnormality 1 | 5

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Respiratory system 7 | 16,393
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Skin and soft tissues 6 | 17,230
Blood and immune system 5 | 16,909
Nervous System 5 | 16,725
Urinary Tract 5 | 16,678
Cardiovascular System 3 | 15,192

Target Family

Enzyme 3 | 4,145
Non-IDG 3 | 12,091
Epigenetic 1 | 242

Compartment GO Term

Male pronucleus 7 | 7
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylcytosine dioxygenase TET3 TET3 Tbio Enzyme -1.96016 82.2 167
Methyltransferase-like protein 23 METTL23 Tdark Enzyme -0.17609 1.92 6
Serine protease 27 PRSS27 Tbio Enzyme -2.20602 159.4 151
Voltage-dependent calcium channel beta subunit-associated regulatory protein CBARP Tbio Non-IDG -2.52425 329.4 58
Protein STPG4 STPG4 Tdark Non-IDG 0.00000 29
Lamin-B receptor LBR Tbio Epigenetic -3.02961 1057.1 134
Surfactant-associated protein 3 SFTA3 Tbio Non-IDG -1.83851 70.4 14